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The map label for this gene is yciC [H]

Identifier: 159898595

GI number: 159898595

Start: 2582192

End: 2583241

Strand: Reverse

Name: yciC [H]

Synonym: Haur_2074

Alternate gene names: 159898595

Gene position: 2583241-2582192 (Counterclockwise)

Preceding gene: 159898596

Following gene: 159898594

Centisome position: 40.7

GC content: 52.76

Gene sequence:

>1050_bases
ATGACGCGCTGTTTTGAAGGAGTTTCTATGAGCGAAGCACCAGCCATTCCGATGACGATTTTGACTGGCTTTTTAGGTGC
AGGGAAAACAACCGTCTTGAATCGCTTGTTGCGTGAGGCCCATGGTCGCAAAATCGCCGTGCTCGTCAACGATTTTGGCG
CGATTAATATCGATGCGCAGTTGGTCGTTGGTATTGAACGCAACGACATTGTAAATCTGGCGAATGGCTGTATTTGTTGT
ACGATTCGCGAAGATTTATTGACTGCGACGCTCGCATTGCTTGATCGTGCAGAGCGGCCTGATGCTATTATTGTGGAAGC
GAGTGGTATCTCTGACCCTCTGGCGATCGCATGGACCTTCCGTTCGCCCGCGTTACGCCCGCACATTACCCTTGATGCCA
TTGTGGCGGTCGTTGATGCTGAGCGCATTTACGAACAACGAGAACAGGTAATGCAGGTCGTTGATCAAATTGCTGCTGCC
GATATGGTGGTGATCAATAAAATCGATTTAGTTCCTCCTCTCCACATTCACGCGGTGATGACGTGGATTCAGTCCATCGT
ACCTCGTGCACGCATTGTGGCTGCGGAGTACGGCGATGTTCCTGTTCAGGTGCTTCTGGGAAGCGGCATCTATCGTATTG
CGTTGCTGCCGAATCAGGAAGTCCCTGAACCGCATACGCATCATCACGATCACGAATGGCAAACCTGGCACTATCAAACC
ACGCAACCATTTCATCTGCGCCGCCTGCAACATGCCTTGCACCACTTACCACCTTCCATTTTTCGCGCCAAAGGGATTGT
CGCTTTAGCCGAAGCACCGGACCGCCAAGCGATTGTTCAGGTTGTGGGCAACCGCGCGAGTGTGCAGCTGAGTACACCTT
GGGGGCTAACCAGCCCCTACAGCCAACTCGTGGTGATTGGCCAGCGCAAGCGTTTTGATGTCGTGGCCCTACGCCAGCAA
TTTCATGCCTGTTTGGCATCAGGTGATCACGAACTGTGCGATCAACGCCCAAGCGCCAATGCATGGTCGCACCCAGATCA
GGCTCCATGA

Upstream 100 bases:

>100_bases
GCAATCAACCGTCACCAGAACTCCGCACACCATCCACGGGAGACAAGGATCATCACCCATCATGTGCGTGTTGTCGGCCT
TATCCGTAGCGAGGAGCAGT

Downstream 100 bases:

>100_bases
GGGACATGTTCATGCAGCATCACCTAACAACGGGTGTGGCGGAACACTGGCTGGTTGGCGTGGAACAAAGCTTTCGTCAG
GCGCATCTGCGATGGACTCC

Product: cobalamin synthesis protein P47K

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MTRCFEGVSMSEAPAIPMTILTGFLGAGKTTVLNRLLREAHGRKIAVLVNDFGAINIDAQLVVGIERNDIVNLANGCICC
TIREDLLTATLALLDRAERPDAIIVEASGISDPLAIAWTFRSPALRPHITLDAIVAVVDAERIYEQREQVMQVVDQIAAA
DMVVINKIDLVPPLHIHAVMTWIQSIVPRARIVAAEYGDVPVQVLLGSGIYRIALLPNQEVPEPHTHHHDHEWQTWHYQT
TQPFHLRRLQHALHHLPPSIFRAKGIVALAEAPDRQAIVQVVGNRASVQLSTPWGLTSPYSQLVVIGQRKRFDVVALRQQ
FHACLASGDHELCDQRPSANAWSHPDQAP

Sequences:

>Translated_349_residues
MTRCFEGVSMSEAPAIPMTILTGFLGAGKTTVLNRLLREAHGRKIAVLVNDFGAINIDAQLVVGIERNDIVNLANGCICC
TIREDLLTATLALLDRAERPDAIIVEASGISDPLAIAWTFRSPALRPHITLDAIVAVVDAERIYEQREQVMQVVDQIAAA
DMVVINKIDLVPPLHIHAVMTWIQSIVPRARIVAAEYGDVPVQVLLGSGIYRIALLPNQEVPEPHTHHHDHEWQTWHYQT
TQPFHLRRLQHALHHLPPSIFRAKGIVALAEAPDRQAIVQVVGNRASVQLSTPWGLTSPYSQLVVIGQRKRFDVVALRQQ
FHACLASGDHELCDQRPSANAWSHPDQAP
>Mature_348_residues
TRCFEGVSMSEAPAIPMTILTGFLGAGKTTVLNRLLREAHGRKIAVLVNDFGAINIDAQLVVGIERNDIVNLANGCICCT
IREDLLTATLALLDRAERPDAIIVEASGISDPLAIAWTFRSPALRPHITLDAIVAVVDAERIYEQREQVMQVVDQIAAAD
MVVINKIDLVPPLHIHAVMTWIQSIVPRARIVAAEYGDVPVQVLLGSGIYRIALLPNQEVPEPHTHHHDHEWQTWHYQTT
QPFHLRRLQHALHHLPPSIFRAKGIVALAEAPDRQAIVQVVGNRASVQLSTPWGLTSPYSQLVVIGQRKRFDVVALRQQF
HACLASGDHELCDQRPSANAWSHPDQAP

Specific function: May bind GTP. Might act as metal chaperone (Potential). Contributes to optimal growth under starvation for zinc [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI126722884, Length=205, Percent_Identity=34.6341463414634, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI223941779, Length=195, Percent_Identity=35.3846153846154, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI148727351, Length=353, Percent_Identity=29.7450424929178, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI33469141, Length=205, Percent_Identity=34.1463414634146, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI146231952, Length=353, Percent_Identity=29.4617563739377, Blast_Score=118, Evalue=9e-27,
Organism=Homo sapiens, GI223941776, Length=192, Percent_Identity=33.3333333333333, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI119120938, Length=134, Percent_Identity=37.3134328358209, Blast_Score=96, Evalue=4e-20,
Organism=Escherichia coli, GI87082430, Length=305, Percent_Identity=31.4754098360656, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1788499, Length=215, Percent_Identity=30.6976744186047, Blast_Score=94, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6324356, Length=222, Percent_Identity=28.8288288288288, Blast_Score=100, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 38602; Mature: 38471

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRCFEGVSMSEAPAIPMTILTGFLGAGKTTVLNRLLREAHGRKIAVLVNDFGAINIDAQ
CCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEEECCCEEEECEE
LVVGIERNDIVNLANGCICCTIREDLLTATLALLDRAERPDAIIVEASGISDPLAIAWTF
EEEEECCCCHHHHCCCEEEEEEHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEEEE
RSPALRPHITLDAIVAVVDAERIYEQREQVMQVVDQIAAADMVVINKIDLVPPLHIHAVM
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHH
TWIQSIVPRARIVAAEYGDVPVQVLLGSGIYRIALLPNQEVPEPHTHHHDHEWQTWHYQT
HHHHHHCCHHEEEEECCCCCCEEEEECCCEEEEEECCCCCCCCCCCCCCCCCCCEEEECC
TQPFHLRRLQHALHHLPPSIFRAKGIVALAEAPDRQAIVQVVGNRASVQLSTPWGLTSPY
CCCHHHHHHHHHHHHCCHHHHHHCCEEEEECCCCHHHHHHHHCCCCEEEEECCCCCCCCC
SQLVVIGQRKRFDVVALRQQFHACLASGDHELCDQRPSANAWSHPDQAP
HHEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TRCFEGVSMSEAPAIPMTILTGFLGAGKTTVLNRLLREAHGRKIAVLVNDFGAINIDAQ
CCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEEECCCEEEECEE
LVVGIERNDIVNLANGCICCTIREDLLTATLALLDRAERPDAIIVEASGISDPLAIAWTF
EEEEECCCCHHHHCCCEEEEEEHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEEEE
RSPALRPHITLDAIVAVVDAERIYEQREQVMQVVDQIAAADMVVINKIDLVPPLHIHAVM
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHH
TWIQSIVPRARIVAAEYGDVPVQVLLGSGIYRIALLPNQEVPEPHTHHHDHEWQTWHYQT
HHHHHHCCHHEEEEECCCCCCEEEEECCCEEEEEECCCCCCCCCCCCCCCCCCCEEEECC
TQPFHLRRLQHALHHLPPSIFRAKGIVALAEAPDRQAIVQVVGNRASVQLSTPWGLTSPY
CCCHHHHHHHHHHHHCCHHHHHHCCEEEEECCCCHHHHHHHHCCCCEEEEECCCCCCCCC
SQLVVIGQRKRFDVVALRQQFHACLASGDHELCDQRPSANAWSHPDQAP
HHEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 9811636 [H]