Click here to switch to the map view.

The map label for this gene is rsbRA [H]

Identifier: 159898418

GI number: 159898418

Start: 2282948

End: 2283982

Strand: Reverse

Name: rsbRA [H]

Synonym: Haur_1894

Alternate gene names: 159898418

Gene position: 2283982-2282948 (Counterclockwise)

Preceding gene: 159898427

Following gene: 159898417

Centisome position: 35.99

GC content: 50.14

Gene sequence:

>1035_bases
ATGTCGCAACCCACAGAGCAAGCGCTGGTCACCAAACGCCTGAAAACCACGGTTTACTGGCTACTCGGCGGTTCATTGAT
TTCGATGTTTTTGTATATGGTGTTGGGCGATTGGATCGCCGTCGGCAGCTTTGCAGTTACCAGTGGGTTGTTAGGCACGG
CTTATTGGCTCATCCTGCGCCAGCATAATCAATCGGCGGTAGTTTTGATGAACATGGCCGCACTATGTTTGGTGATTGTT
GGATCATTTCGCTTTTTCACCTTGCTCTCGATCGCTACGGTTACAATTATTTCGATTGTGCTGGTGCTGCCGTTTGTCGA
TAGCCGACGACTGCTCGGCATTTGTGGACTTGCATGGGTTGTTAGTATTATCAGCATCGCCAATCGGCTGCGGATCGATC
AATTTCCATGGGCCGAGATGCCAATTCGCGTTTCACTCAACTCGGTCTCGATTTTGGTGGTGATGGGCCTGCTCTGGCAA
ATTCATCGTCAACTAACCAATAGTCTGCAAGCCAGCGAACGCTCGAACCAAGCCTTACGCGCTAGCCAACAATCGCTCGA
ACAGCAGGTTGAACAGCGCACCGCCGCCCTGCAAAAAGCCCTACAAGAAGTGCAAGCCCAAGCCGACAGCCAAGCAGTAT
TGGCTCAACAACTAGCCGAGCAACAAACCACCATACGCAGCCTGAGTGTACCAATTTTGCCAATAACCCAGCATAGTTTG
GTTGTGCCATTAATTGGCGATTTGGATGCTGAACGCTTGGGCACATTGGTAGAACAAATTCTAACCAACCTCAAAAGTCA
ACGCACCCGCCATTTAATTCTTGATGTTACTGGTGTACCAACTTTAGATCGCGATGCTGGCCACAGTTTGCTCAAAGTTA
GCAACGCTGCTCGCTTGTTGGGAGCCAAAACCACCTTAATTGGCGTGCGGCCTGATGTGGCCGAAATGCTCGTGAGCATT
GGGCTTGATTTGCGCTCGATTGGCAGCGAAAAAGATTTACAAAGTGTGGTGTATGGCCTCGTTCGCCATGCCTAA

Upstream 100 bases:

>100_bases
TAGTGAACAACCATTCGCCGATAAACGAGCTTGCACTCAAGTATAAAACTAGGTATGCTTAAGCCGATTCTCCCCTTCCA
ACGGCAAAGGTAGGTGCGCA

Downstream 100 bases:

>100_bases
AATCTGCTATGATCAAATCAATTCGGCTCAGCTCATAAAGGAACATCTATGCTGCTCGTTGCTAGCTACCTTGCCCCAAG
CACCATTCATGGCATCGGTG

Product: anti-sigma-factor antagonist

Products: NA

Alternate protein names: Stressosome protein rsbRA [H]

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MSQPTEQALVTKRLKTTVYWLLGGSLISMFLYMVLGDWIAVGSFAVTSGLLGTAYWLILRQHNQSAVVLMNMAALCLVIV
GSFRFFTLLSIATVTIISIVLVLPFVDSRRLLGICGLAWVVSIISIANRLRIDQFPWAEMPIRVSLNSVSILVVMGLLWQ
IHRQLTNSLQASERSNQALRASQQSLEQQVEQRTAALQKALQEVQAQADSQAVLAQQLAEQQTTIRSLSVPILPITQHSL
VVPLIGDLDAERLGTLVEQILTNLKSQRTRHLILDVTGVPTLDRDAGHSLLKVSNAARLLGAKTTLIGVRPDVAEMLVSI
GLDLRSIGSEKDLQSVVYGLVRHA

Sequences:

>Translated_344_residues
MSQPTEQALVTKRLKTTVYWLLGGSLISMFLYMVLGDWIAVGSFAVTSGLLGTAYWLILRQHNQSAVVLMNMAALCLVIV
GSFRFFTLLSIATVTIISIVLVLPFVDSRRLLGICGLAWVVSIISIANRLRIDQFPWAEMPIRVSLNSVSILVVMGLLWQ
IHRQLTNSLQASERSNQALRASQQSLEQQVEQRTAALQKALQEVQAQADSQAVLAQQLAEQQTTIRSLSVPILPITQHSL
VVPLIGDLDAERLGTLVEQILTNLKSQRTRHLILDVTGVPTLDRDAGHSLLKVSNAARLLGAKTTLIGVRPDVAEMLVSI
GLDLRSIGSEKDLQSVVYGLVRHA
>Mature_343_residues
SQPTEQALVTKRLKTTVYWLLGGSLISMFLYMVLGDWIAVGSFAVTSGLLGTAYWLILRQHNQSAVVLMNMAALCLVIVG
SFRFFTLLSIATVTIISIVLVLPFVDSRRLLGICGLAWVVSIISIANRLRIDQFPWAEMPIRVSLNSVSILVVMGLLWQI
HRQLTNSLQASERSNQALRASQQSLEQQVEQRTAALQKALQEVQAQADSQAVLAQQLAEQQTTIRSLSVPILPITQHSLV
VPLIGDLDAERLGTLVEQILTNLKSQRTRHLILDVTGVPTLDRDAGHSLLKVSNAARLLGAKTTLIGVRPDVAEMLVSIG
LDLRSIGSEKDLQSVVYGLVRHA

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014792
- InterPro:   IPR002645 [H]

Pfam domain/function: PF08678 Rsbr_N; PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 37726; Mature: 37595

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQPTEQALVTKRLKTTVYWLLGGSLISMFLYMVLGDWIAVGSFAVTSGLLGTAYWLILR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QHNQSAVVLMNMAALCLVIVGSFRFFTLLSIATVTIISIVLVLPFVDSRRLLGICGLAWV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
VSIISIANRLRIDQFPWAEMPIRVSLNSVSILVVMGLLWQIHRQLTNSLQASERSNQALR
HHHHHHHHHHCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASQQSLEQQVEQRTAALQKALQEVQAQADSQAVLAQQLAEQQTTIRSLSVPILPITQHSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCE
VVPLIGDLDAERLGTLVEQILTNLKSQRTRHLILDVTGVPTLDRDAGHSLLKVSNAARLL
EEHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHH
GAKTTLIGVRPDVAEMLVSIGLDLRSIGSEKDLQSVVYGLVRHA
CCHHHEEECCCHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SQPTEQALVTKRLKTTVYWLLGGSLISMFLYMVLGDWIAVGSFAVTSGLLGTAYWLILR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QHNQSAVVLMNMAALCLVIVGSFRFFTLLSIATVTIISIVLVLPFVDSRRLLGICGLAWV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
VSIISIANRLRIDQFPWAEMPIRVSLNSVSILVVMGLLWQIHRQLTNSLQASERSNQALR
HHHHHHHHHHCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASQQSLEQQVEQRTAALQKALQEVQAQADSQAVLAQQLAEQQTTIRSLSVPILPITQHSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCE
VVPLIGDLDAERLGTLVEQILTNLKSQRTRHLILDVTGVPTLDRDAGHSLLKVSNAARLL
EEHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHH
GAKTTLIGVRPDVAEMLVSIGLDLRSIGSEKDLQSVVYGLVRHA
CCHHHEEECCCHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 11157946; 10329124 [H]