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The map label for this gene is fabG [C]

Identifier: 159898375

GI number: 159898375

Start: 2152517

End: 2153257

Strand: Direct

Name: fabG [C]

Synonym: Haur_1851

Alternate gene names: 159898375

Gene position: 2152517-2153257 (Clockwise)

Preceding gene: 159898374

Following gene: 159898378

Centisome position: 33.92

GC content: 51.82

Gene sequence:

>741_bases
GTGCCACAGGATTTTAGTGGGCAAGTTGCCTTAGTAACTGGAGCTTCGCGCGGCATTGGAGCCGAAATTAGTCGCCAGCT
GGCGCAACGTGGAGCCGATATCGTGATTAATTATCGCAGCAAAGCCTCGCGAGCCGAAGCTGTTGCCAGCGAAATAACTG
CGCTTGGCCGGACTGCACTCCTGGCTCAGGCCGATTTAACCCAAATTAATGATTTGATTACCACCCAAACCCAAATTCAA
CAAGCCTTTGGCAAACTCGATTTGTTGGTACTCAATGCCAGCGGTGGCCTTGAAAAAGATAAACCCGCTAGCTACGCCAT
GGATCTCAATCTCACTGCTCAAGTGCAAACCGTCGAAACCATGTTGCCATTGATGCAAGCTGGCAGTTGCATTGTTTTCG
TCACCAGCCACTGGGCGCATTTCTATGGCGAACGACCAATTATCGCTGGCTACGAGCCAGTTGCTAGCAGCAAAAAAGCT
GGCGAAATGGCGCTGCGCGAACGGATTGATCAATTTACCCAGCGCGGAATTCATTTTTATGTGGTCAGCGGCGATATGAT
CGAAGGCACGATCACGCCCAAATTGCTTGATCGTGCCCAGCCTGGCTTTTTGGCCGCCCGCAAAGAACACAGCCCTGAGC
CAATTCCCACGATTGAAGAATTTGCCAGCGCGATTGTAGCAACCGCCGCCGATCGCAGCCAAGCCAATGGCCACACTGTG
TTCGTTGGGCCGATTATTTAA

Upstream 100 bases:

>100_bases
CCTCTACAATCTGACGACGAACCTCTAGCCCACTATTGTATAATCGTGCTAGCTTTCTCCAGTTTGGGGAAACCAACCGA
GCTACGTGAAAGGATCGTGT

Downstream 100 bases:

>100_bases
GATAACTTAATAAGGTAAATAAAGAATCCTCATGGCAGATATAATTGACTTCCATGAGGATTCTGTTTAGTAGTCTAGGG
CATCGATTTGAAAACTGAGT

Product: short-chain dehydrogenase/reductase SDR

Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]

Alternate protein names: ORFC [H]

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MPQDFSGQVALVTGASRGIGAEISRQLAQRGADIVINYRSKASRAEAVASEITALGRTALLAQADLTQINDLITTQTQIQ
QAFGKLDLLVLNASGGLEKDKPASYAMDLNLTAQVQTVETMLPLMQAGSCIVFVTSHWAHFYGERPIIAGYEPVASSKKA
GEMALRERIDQFTQRGIHFYVVSGDMIEGTITPKLLDRAQPGFLAARKEHSPEPIPTIEEFASAIVATAADRSQANGHTV
FVGPII

Sequences:

>Translated_246_residues
MPQDFSGQVALVTGASRGIGAEISRQLAQRGADIVINYRSKASRAEAVASEITALGRTALLAQADLTQINDLITTQTQIQ
QAFGKLDLLVLNASGGLEKDKPASYAMDLNLTAQVQTVETMLPLMQAGSCIVFVTSHWAHFYGERPIIAGYEPVASSKKA
GEMALRERIDQFTQRGIHFYVVSGDMIEGTITPKLLDRAQPGFLAARKEHSPEPIPTIEEFASAIVATAADRSQANGHTV
FVGPII
>Mature_245_residues
PQDFSGQVALVTGASRGIGAEISRQLAQRGADIVINYRSKASRAEAVASEITALGRTALLAQADLTQINDLITTQTQIQQ
AFGKLDLLVLNASGGLEKDKPASYAMDLNLTAQVQTVETMLPLMQAGSCIVFVTSHWAHFYGERPIIAGYEPVASSKKAG
EMALRERIDQFTQRGIHFYVVSGDMIEGTITPKLLDRAQPGFLAARKEHSPEPIPTIEEFASAIVATAADRSQANGHTVF
VGPII

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100 [C]

Molecular weight: Translated: 26422; Mature: 26291

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQDFSGQVALVTGASRGIGAEISRQLAQRGADIVINYRSKASRAEAVASEITALGRTAL
CCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHH
LAQADLTQINDLITTQTQIQQAFGKLDLLVLNASGGLEKDKPASYAMDLNLTAQVQTVET
HHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCEEEECCEEEHHHHHHH
MLPLMQAGSCIVFVTSHWAHFYGERPIIAGYEPVASSKKAGEMALRERIDQFTQRGIHFY
HHHHHHCCCEEEEEEHHHHHHHCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHCCEEEE
VVSGDMIEGTITPKLLDRAQPGFLAARKEHSPEPIPTIEEFASAIVATAADRSQANGHTV
EEECCEEECCCCHHHHHCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEE
FVGPII
EEECCC
>Mature Secondary Structure 
PQDFSGQVALVTGASRGIGAEISRQLAQRGADIVINYRSKASRAEAVASEITALGRTAL
CCCCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHH
LAQADLTQINDLITTQTQIQQAFGKLDLLVLNASGGLEKDKPASYAMDLNLTAQVQTVET
HHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCEEEECCEEEHHHHHHH
MLPLMQAGSCIVFVTSHWAHFYGERPIIAGYEPVASSKKAGEMALRERIDQFTQRGIHFY
HHHHHHCCCEEEEEEHHHHHHHCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHCCEEEE
VVSGDMIEGTITPKLLDRAQPGFLAARKEHSPEPIPTIEEFASAIVATAADRSQANGHTV
EEECCEEECCCCHHHHHCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEE
FVGPII
EEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]

Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8868443 [H]