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The map label for this gene is macB [H]

Identifier: 159898128

GI number: 159898128

Start: 1861123

End: 1862454

Strand: Direct

Name: macB [H]

Synonym: Haur_1604

Alternate gene names: 159898128

Gene position: 1861123-1862454 (Clockwise)

Preceding gene: 159898127

Following gene: 159898129

Centisome position: 29.32

GC content: 52.78

Gene sequence:

>1332_bases
ATGATGACAACGCTTGATGTGCAAACTGTTCCCACGCCCGCTCCCGCCGCCAGCGACGACATCCTATTTCAGCCGATTGA
AGCTAGCTCAAGTGGCTTTGGCAGCCTATGGGAAGTGGTGCGCATTTCGTTTGGCAGCCTGTTGGCTAATAAAGTGCGCT
CGTTGCTGACGATGTTGGGGGTGATTATTGGGGTGGCCTCGGTGGTTTCGTTGCTGGCGCTTGGCAACGGGGCAAGTGCT
TCGATTACTGGCGAAATTGAGGCAATTGGCACGAACGTCCTGACAATTTCGGCTGGCTCACAAAATCGTGGGCCTGGCAA
TGCGACTGCTGCCCAAAACTTGACGATGGACGATGCGCGGGCGATTGAAGCCTTGCAACTGCCAGTGATTGGCGTGGCTC
CCCAACTTAACTCAAATGCCCAAATTGTCGCCAAATCGGCGGATAAAAGCGCCCAAATTGTTGGCATAACTCCGTCGTTT
CAAGTGGTGAACAACTTGGCCATGCAACAGGGCAGTTTTATCACTGAGGAGCATTTACAAGGCGCAAATACCGTGATCGT
CTTGGGTTCGACCTTGGCCAAAGATTTATTTGGCAATGGTCAAGCGGTTGGCCAAACCGTGCGGATCAACAACCAAAGTT
TGCGCGTGGTGGGGGTGCTTACGCCGCAGGGTGGCAGTGCCTTTGGCTCGGAAGATGATCGGGCTTATATTCCGATTACC
ACGGCCCAAAAACGCCTGTTTAACGCCCGCACTCCTGATGGCAATGGCTATCGAGTTGGCTCGATTACGCTTTCGGCGAT
TAATGCTAGCGATCTTGATGCGCTGCAATCGCGGGTAAGCATGTTGCTGCGTGAGCGCCATCATCTCAAACTTGATGGTA
GCGCCGATGATTTTAATGTAATCAACCAAGCCGAAATTTTGGGCACGCTGACCACGATCACCTCAATGATGACCCTCTTT
CTGGCGGCGGTAGCGGGGATTTCGCTGCTGGTTGGCGGAATTGGGATTATGAATATTATGCTGGTGAGTGTGACCGAGCG
TACTCGAGAAATTGGTTTGCGCAAGGCTGTCGGCGCACGTAGCCATCATATTTTGATGCAATTTGTGGTTGAGGCGGCGG
TGCTGAGTATGACCGGCGGTATGATTGGCCTGATGCTTGGCAGCATTATTCCAATTGTCGTAACCCAAATGGGCTTGCTC
GATGCGCCGATTGATCTGCAAACTGTCGGAGTCGCGATCGGCTTCTCGCTGGGGGTTGGCTTGTTCTTTGGAATTTACCC
TGCTCAACGGGCCGCCAAATTGAACCCAATTGATGCCTTGCGCCACGAATAA

Upstream 100 bases:

>100_bases
TGCTGGTGACCCACGAACATGACGTGGCGGCCTATGCGGCGCGAGTGCTGACCATGCGCGATGGGCAGTTGATTGGCGAT
CAGCGTAATTAAAGGATGCA

Downstream 100 bases:

>100_bases
TGAGCGCCAAGCAATCCTCGCACAAATCCCTGTTTCATGTGGTTGAGACAGGGATTTTCGTTGGTTAACGGCTTAATAAT
CAGTACAATCAGCACCTAGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MMTTLDVQTVPTPAPAASDDILFQPIEASSSGFGSLWEVVRISFGSLLANKVRSLLTMLGVIIGVASVVSLLALGNGASA
SITGEIEAIGTNVLTISAGSQNRGPGNATAAQNLTMDDARAIEALQLPVIGVAPQLNSNAQIVAKSADKSAQIVGITPSF
QVVNNLAMQQGSFITEEHLQGANTVIVLGSTLAKDLFGNGQAVGQTVRINNQSLRVVGVLTPQGGSAFGSEDDRAYIPIT
TAQKRLFNARTPDGNGYRVGSITLSAINASDLDALQSRVSMLLRERHHLKLDGSADDFNVINQAEILGTLTTITSMMTLF
LAAVAGISLLVGGIGIMNIMLVSVTERTREIGLRKAVGARSHHILMQFVVEAAVLSMTGGMIGLMLGSIIPIVVTQMGLL
DAPIDLQTVGVAIGFSLGVGLFFGIYPAQRAAKLNPIDALRHE

Sequences:

>Translated_443_residues
MMTTLDVQTVPTPAPAASDDILFQPIEASSSGFGSLWEVVRISFGSLLANKVRSLLTMLGVIIGVASVVSLLALGNGASA
SITGEIEAIGTNVLTISAGSQNRGPGNATAAQNLTMDDARAIEALQLPVIGVAPQLNSNAQIVAKSADKSAQIVGITPSF
QVVNNLAMQQGSFITEEHLQGANTVIVLGSTLAKDLFGNGQAVGQTVRINNQSLRVVGVLTPQGGSAFGSEDDRAYIPIT
TAQKRLFNARTPDGNGYRVGSITLSAINASDLDALQSRVSMLLRERHHLKLDGSADDFNVINQAEILGTLTTITSMMTLF
LAAVAGISLLVGGIGIMNIMLVSVTERTREIGLRKAVGARSHHILMQFVVEAAVLSMTGGMIGLMLGSIIPIVVTQMGLL
DAPIDLQTVGVAIGFSLGVGLFFGIYPAQRAAKLNPIDALRHE
>Mature_443_residues
MMTTLDVQTVPTPAPAASDDILFQPIEASSSGFGSLWEVVRISFGSLLANKVRSLLTMLGVIIGVASVVSLLALGNGASA
SITGEIEAIGTNVLTISAGSQNRGPGNATAAQNLTMDDARAIEALQLPVIGVAPQLNSNAQIVAKSADKSAQIVGITPSF
QVVNNLAMQQGSFITEEHLQGANTVIVLGSTLAKDLFGNGQAVGQTVRINNQSLRVVGVLTPQGGSAFGSEDDRAYIPIT
TAQKRLFNARTPDGNGYRVGSITLSAINASDLDALQSRVSMLLRERHHLKLDGSADDFNVINQAEILGTLTTITSMMTLF
LAAVAGISLLVGGIGIMNIMLVSVTERTREIGLRKAVGARSHHILMQFVVEAAVLSMTGGMIGLMLGSIIPIVVTQMGLL
DAPIDLQTVGVAIGFSLGVGLFFGIYPAQRAAKLNPIDALRHE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=417, Percent_Identity=35.9712230215827, Blast_Score=206, Evalue=3e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 46189; Mature: 46189

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTTLDVQTVPTPAPAASDDILFQPIEASSSGFGSLWEVVRISFGSLLANKVRSLLTMLG
CCEEEEEEECCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIIGVASVVSLLALGNGASASITGEIEAIGTNVLTISAGSQNRGPGNATAAQNLTMDDAR
HHHHHHHHHHHHHCCCCCCCEEEEEEEEECCEEEEEECCCCCCCCCCCCHHCCCCCHHHH
AIEALQLPVIGVAPQLNSNAQIVAKSADKSAQIVGITPSFQVVNNLAMQQGSFITEEHLQ
HHHHHHCCEEEECCCCCCCCEEEEECCCCCCEEEEECCCHHHHHHHHHHCCCCCCHHHCC
GANTVIVLGSTLAKDLFGNGQAVGQTVRINNQSLRVVGVLTPQGGSAFGSEDDRAYIPIT
CCCEEEEECHHHHHHHCCCCHHCCCEEEECCCCEEEEEEEECCCCCCCCCCCCCEEEEEE
TAQKRLFNARTPDGNGYRVGSITLSAINASDLDALQSRVSMLLRERHHLKLDGSADDFNV
HHHHHHHCCCCCCCCCEEEEEEEEEEECCHHHHHHHHHHHHHHHHHCCEEECCCCCCCHH
INQAEILGTLTTITSMMTLFLAAVAGISLLVGGIGIMNIMLVSVTERTREIGLRKAVGAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SHHILMQFVVEAAVLSMTGGMIGLMLGSIIPIVVTQMGLLDAPIDLQTVGVAIGFSLGVG
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
LFFGIYPAQRAAKLNPIDALRHE
HHHHCCCHHHCCCCCCHHHHCCC
>Mature Secondary Structure
MMTTLDVQTVPTPAPAASDDILFQPIEASSSGFGSLWEVVRISFGSLLANKVRSLLTMLG
CCEEEEEEECCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIIGVASVVSLLALGNGASASITGEIEAIGTNVLTISAGSQNRGPGNATAAQNLTMDDAR
HHHHHHHHHHHHHCCCCCCCEEEEEEEEECCEEEEEECCCCCCCCCCCCHHCCCCCHHHH
AIEALQLPVIGVAPQLNSNAQIVAKSADKSAQIVGITPSFQVVNNLAMQQGSFITEEHLQ
HHHHHHCCEEEECCCCCCCCEEEEECCCCCCEEEEECCCHHHHHHHHHHCCCCCCHHHCC
GANTVIVLGSTLAKDLFGNGQAVGQTVRINNQSLRVVGVLTPQGGSAFGSEDDRAYIPIT
CCCEEEEECHHHHHHHCCCCHHCCCEEEECCCCEEEEEEEECCCCCCCCCCCCCEEEEEE
TAQKRLFNARTPDGNGYRVGSITLSAINASDLDALQSRVSMLLRERHHLKLDGSADDFNV
HHHHHHHCCCCCCCCCEEEEEEEEEEECCHHHHHHHHHHHHHHHHHCCEEECCCCCCCHH
INQAEILGTLTTITSMMTLFLAAVAGISLLVGGIGIMNIMLVSVTERTREIGLRKAVGAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SHHILMQFVVEAAVLSMTGGMIGLMLGSIIPIVVTQMGLLDAPIDLQTVGVAIGFSLGVG
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
LFFGIYPAQRAAKLNPIDALRHE
HHHHCCCHHHCCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA