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The map label for this gene is dppA [H]

Identifier: 159898129

GI number: 159898129

Start: 1862688

End: 1864475

Strand: Direct

Name: dppA [H]

Synonym: Haur_1605

Alternate gene names: 159898129

Gene position: 1862688-1864475 (Clockwise)

Preceding gene: 159898128

Following gene: 159898130

Centisome position: 29.35

GC content: 52.01

Gene sequence:

>1788_bases
ATGTCTTTCCGTAAACCAGGTAAGCGTTCGATTGGCTGGCTATTGCTCTTGGTATTGATGATACCGTTGATAGCTGCCTG
TGGCGAAACCGCCGCTCCAACCGCAACTGTTGGCTCAACTCCCGCTACTGGTGGCGAACCCACTGCTGCCCCAACTACCG
CTCCTACAGATGACACCGCTGCAGCCACACCAACCGACGCCGCTGCTGCAACCGAAGAACCAACCATGGGCGATGCTGAT
AAGTATCTGGTATTTGGTGGTTCGGGCGAACCCGATTCACTCGATTCGATGGATACGACCACGGGTACTGCCTTGATTGT
AACCCGCCAAATCCAAGAATCGTTGTTGGGTTTCAAGGCTGGTACGTTGGAAGTTGTGCCCGAATTGGCGACCAAGTGGG
AGCCAAACGCCGATGCAACCGAGTGGACGTTTACCCTGCGCGAAGGGGTTAAATTCTCTGATGGCACCGACTTCAACGCT
GATGCAGTAGTTTTCAACTTCCAGCGCTTGTTTGTGCCTGATTTTGAGTTTGGCTTCCGTGCCGAAGGCAAGCAATACAA
CATCGTGCCCGATATTTTTGGTGGCTATGCTGGCGACCCCAACAGTGCCTTCAAAGAAATTATGGCAGTTGATCCAACCA
CGGTTAAGTTTGTTTTGACGCGGCCTGTGCCGTTGTTGCCAAGCTATTTGGCCGCTTCCTACTTCGGAATTTCATCGCCC
GAAGCAGTCAAGGCTGCCAAAGAAAAATATGGCTCACCAGAAGTTGGTGGCGTTGGGACTGGCCCCTTCAAGTTTGAGCG
CTGGGATGCTGGTCAAAGCATCACCTTGGTGCGCAACGAAGATTATTGGGGCGACAAGGCCAAAATGCCAGGTGTGGTTG
TGCGCTTTATCGCCGAAGCACCCCAACGTTTGGCCGAGCTTGAAGCTGGCACAATTGATTTCACAATCAACTTGAGCGCT
GATAGCCGCGATAAAATTGCTTCAAGCGCCGATTTGCAAGTGGTTGATTTGACTCCATTCAACATTGCCTACTTGTCGTT
GAACATGAACAACAAGCCTTTTGACGATGTGCGGGTTCGTCAGGCGGTTGCCTATGCCATCAACAAGCAAGAAATTCTTG
ATGCCTCGTATGGCGGCGTTGGCTCAATTGCCGACGACTTCTTGCCCGATGGATTGGCTGAATATCGGGCGACTGACCTC
GAACCATATGCTTATGATCCAGAAAAAGCCAAAGCCTTGTTGGCCGAAGCTGGCTATGCCGATGGCTTTAGCACCATGGT
CTTGACCGATGGAACTGAATTGCCCTTGGAATTGTGGTATATGCCGGTTTCACGGCCTTACTACCCCGATGCTAAGTCAG
TGGCTGAACTCTACGCCGCCCAACTTTCCGACGTTGGGATCAAGGTTGAACTCAAGACCGAAGATTGGGGCGTGTATCTC
GATAACTGGGATGCTGGCCTGAAAAACGGGATGGTGATGTTGGGTTGGACGGGCGACTATGGCGACCCTAACAACTTCTT
GTTCACTCACTTTGGCCCAGGCAACGCCGACGAAGCTGGTTATACTAACGAGAAAGTTTGGCAATTGCTGGCCGATGCTG
GTGGCGCTTCCTCGCCCGCCGAGTCAATTCGGCTGTTCCAAGAAGCTGGCAAGTTGATTAACACCGATTTGCCACGGATT
CCGATCGTGCATGCTCCACCCGTATTGGCTGCTAAAAAAGCCTTGCAAGGCTGGGTGCCAAATCCAACTGGTGGCGAATC
ATTCGCACCGATCTCAATCACGAAATAA

Upstream 100 bases:

>100_bases
ACATGAATTTTGCCCTATAATACGATAACCGCACCGCTCTGTATCAGTGGAGATGACGAGAGTAAGACTATCTTAGGAAC
GCATAGCTTAAGGAGGTCTC

Downstream 100 bases:

>100_bases
CCAATAGCCGAGCCTACGCCGCTTGTTAGCACTTAATTCTAACAAGCGGCGTATAGTAAGGAAGAATGCATGGTTGGGTA
TATTTTTCGTCGGCTGCTTG

Product: extracellular solute-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 595; Mature: 594

Protein sequence:

>595_residues
MSFRKPGKRSIGWLLLLVLMIPLIAACGETAAPTATVGSTPATGGEPTAAPTTAPTDDTAAATPTDAAAATEEPTMGDAD
KYLVFGGSGEPDSLDSMDTTTGTALIVTRQIQESLLGFKAGTLEVVPELATKWEPNADATEWTFTLREGVKFSDGTDFNA
DAVVFNFQRLFVPDFEFGFRAEGKQYNIVPDIFGGYAGDPNSAFKEIMAVDPTTVKFVLTRPVPLLPSYLAASYFGISSP
EAVKAAKEKYGSPEVGGVGTGPFKFERWDAGQSITLVRNEDYWGDKAKMPGVVVRFIAEAPQRLAELEAGTIDFTINLSA
DSRDKIASSADLQVVDLTPFNIAYLSLNMNNKPFDDVRVRQAVAYAINKQEILDASYGGVGSIADDFLPDGLAEYRATDL
EPYAYDPEKAKALLAEAGYADGFSTMVLTDGTELPLELWYMPVSRPYYPDAKSVAELYAAQLSDVGIKVELKTEDWGVYL
DNWDAGLKNGMVMLGWTGDYGDPNNFLFTHFGPGNADEAGYTNEKVWQLLADAGGASSPAESIRLFQEAGKLINTDLPRI
PIVHAPPVLAAKKALQGWVPNPTGGESFAPISITK

Sequences:

>Translated_595_residues
MSFRKPGKRSIGWLLLLVLMIPLIAACGETAAPTATVGSTPATGGEPTAAPTTAPTDDTAAATPTDAAAATEEPTMGDAD
KYLVFGGSGEPDSLDSMDTTTGTALIVTRQIQESLLGFKAGTLEVVPELATKWEPNADATEWTFTLREGVKFSDGTDFNA
DAVVFNFQRLFVPDFEFGFRAEGKQYNIVPDIFGGYAGDPNSAFKEIMAVDPTTVKFVLTRPVPLLPSYLAASYFGISSP
EAVKAAKEKYGSPEVGGVGTGPFKFERWDAGQSITLVRNEDYWGDKAKMPGVVVRFIAEAPQRLAELEAGTIDFTINLSA
DSRDKIASSADLQVVDLTPFNIAYLSLNMNNKPFDDVRVRQAVAYAINKQEILDASYGGVGSIADDFLPDGLAEYRATDL
EPYAYDPEKAKALLAEAGYADGFSTMVLTDGTELPLELWYMPVSRPYYPDAKSVAELYAAQLSDVGIKVELKTEDWGVYL
DNWDAGLKNGMVMLGWTGDYGDPNNFLFTHFGPGNADEAGYTNEKVWQLLADAGGASSPAESIRLFQEAGKLINTDLPRI
PIVHAPPVLAAKKALQGWVPNPTGGESFAPISITK
>Mature_594_residues
SFRKPGKRSIGWLLLLVLMIPLIAACGETAAPTATVGSTPATGGEPTAAPTTAPTDDTAAATPTDAAAATEEPTMGDADK
YLVFGGSGEPDSLDSMDTTTGTALIVTRQIQESLLGFKAGTLEVVPELATKWEPNADATEWTFTLREGVKFSDGTDFNAD
AVVFNFQRLFVPDFEFGFRAEGKQYNIVPDIFGGYAGDPNSAFKEIMAVDPTTVKFVLTRPVPLLPSYLAASYFGISSPE
AVKAAKEKYGSPEVGGVGTGPFKFERWDAGQSITLVRNEDYWGDKAKMPGVVVRFIAEAPQRLAELEAGTIDFTINLSAD
SRDKIASSADLQVVDLTPFNIAYLSLNMNNKPFDDVRVRQAVAYAINKQEILDASYGGVGSIADDFLPDGLAEYRATDLE
PYAYDPEKAKALLAEAGYADGFSTMVLTDGTELPLELWYMPVSRPYYPDAKSVAELYAAQLSDVGIKVELKTEDWGVYLD
NWDAGLKNGMVMLGWTGDYGDPNNFLFTHFGPGNADEAGYTNEKVWQLLADAGGASSPAESIRLFQEAGKLINTDLPRIP
IVHAPPVLAAKKALQGWVPNPTGGESFAPISITK

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=527, Percent_Identity=33.2068311195446, Blast_Score=269, Evalue=3e-73,
Organism=Escherichia coli, GI1787052, Length=509, Percent_Identity=30.6483300589391, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI1787762, Length=528, Percent_Identity=26.8939393939394, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI1787551, Length=547, Percent_Identity=27.2394881170018, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1789887, Length=423, Percent_Identity=27.1867612293144, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI87081878, Length=513, Percent_Identity=26.5107212475634, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1787495, Length=525, Percent_Identity=25.7142857142857, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1789397, Length=509, Percent_Identity=25.147347740668, Blast_Score=113, Evalue=3e-26,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 63902; Mature: 63771

Theoretical pI: Translated: 4.18; Mature: 4.18

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS01040 SBP_BACTERIAL_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFRKPGKRSIGWLLLLVLMIPLIAACGETAAPTATVGSTPATGGEPTAAPTTAPTDDTA
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AATPTDAAAATEEPTMGDADKYLVFGGSGEPDSLDSMDTTTGTALIVTRQIQESLLGFKA
CCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHCCCC
GTLEVVPELATKWEPNADATEWTFTLREGVKFSDGTDFNADAVVFNFQRLFVPDFEFGFR
CHHHHHHHHHHCCCCCCCCCEEEEEHHCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCC
AEGKQYNIVPDIFGGYAGDPNSAFKEIMAVDPTTVKFVLTRPVPLLPSYLAASYFGISSP
CCCCEEECCHHHHCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHCCCCCC
EAVKAAKEKYGSPEVGGVGTGPFKFERWDAGQSITLVRNEDYWGDKAKMPGVVVRFIAEA
HHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCEEEEEECCCCCCCCCCCCHHHHHHHHHH
PQRLAELEAGTIDFTINLSADSRDKIASSADLQVVDLTPFNIAYLSLNMNNKPFDDVRVR
HHHHHHCCCCEEEEEEEECCCCHHHHCCCCCEEEEEECCCEEEEEEEECCCCCCHHHHHH
QAVAYAINKQEILDASYGGVGSIADDFLPDGLAEYRATDLEPYAYDPEKAKALLAEAGYA
HHHHHHHCHHHHHHCCCCCCCCHHHHHCCCCHHHHHCCCCCCCCCCHHHHHHHHHHCCCC
DGFSTMVLTDGTELPLELWYMPVSRPYYPDAKSVAELYAAQLSDVGIKVELKTEDWGVYL
CCCEEEEEECCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCEEEE
DNWDAGLKNGMVMLGWTGDYGDPNNFLFTHFGPGNADEAGYTNEKVWQLLADAGGASSPA
ECCCCCCCCCEEEEEECCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCHH
ESIRLFQEAGKLINTDLPRIPIVHAPPVLAAKKALQGWVPNPTGGESFAPISITK
HHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHHCCCCCCCCCCCCCCEEECC
>Mature Secondary Structure 
SFRKPGKRSIGWLLLLVLMIPLIAACGETAAPTATVGSTPATGGEPTAAPTTAPTDDTA
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AATPTDAAAATEEPTMGDADKYLVFGGSGEPDSLDSMDTTTGTALIVTRQIQESLLGFKA
CCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHCCCC
GTLEVVPELATKWEPNADATEWTFTLREGVKFSDGTDFNADAVVFNFQRLFVPDFEFGFR
CHHHHHHHHHHCCCCCCCCCEEEEEHHCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCC
AEGKQYNIVPDIFGGYAGDPNSAFKEIMAVDPTTVKFVLTRPVPLLPSYLAASYFGISSP
CCCCEEECCHHHHCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHCCCCCC
EAVKAAKEKYGSPEVGGVGTGPFKFERWDAGQSITLVRNEDYWGDKAKMPGVVVRFIAEA
HHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCEEEEEECCCCCCCCCCCCHHHHHHHHHH
PQRLAELEAGTIDFTINLSADSRDKIASSADLQVVDLTPFNIAYLSLNMNNKPFDDVRVR
HHHHHHCCCCEEEEEEEECCCCHHHHCCCCCEEEEEECCCEEEEEEEECCCCCCHHHHHH
QAVAYAINKQEILDASYGGVGSIADDFLPDGLAEYRATDLEPYAYDPEKAKALLAEAGYA
HHHHHHHCHHHHHHCCCCCCCCHHHHHCCCCHHHHHCCCCCCCCCCHHHHHHHHHHCCCC
DGFSTMVLTDGTELPLELWYMPVSRPYYPDAKSVAELYAAQLSDVGIKVELKTEDWGVYL
CCCEEEEEECCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCEEEE
DNWDAGLKNGMVMLGWTGDYGDPNNFLFTHFGPGNADEAGYTNEKVWQLLADAGGASSPA
ECCCCCCCCCEEEEEECCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCHH
ESIRLFQEAGKLINTDLPRIPIVHAPPVLAAKKALQGWVPNPTGGESFAPISITK
HHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHHCCCCCCCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]