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The map label for this gene is nagD [H]

Identifier: 159898116

GI number: 159898116

Start: 1845412

End: 1846212

Strand: Direct

Name: nagD [H]

Synonym: Haur_1592

Alternate gene names: 159898116

Gene position: 1845412-1846212 (Clockwise)

Preceding gene: 159898112

Following gene: 159898117

Centisome position: 29.08

GC content: 54.81

Gene sequence:

>801_bases
ATGCTCAATCTCAAGCAGCTCAAGCTTGTTTTGCTCGATATGGATGGGGTGCTGCATCGCGGCGGGGAGATTTTACCAGG
TGCGGCAGAGTTGACGACTGTGCTTGATCGCTTAGGCTTAGGCTATGCCTGTTTGACCAATAATTCATCGCAATTGCCTG
CCACCTTCGCCCGTCATCTGCAAGATTTAGGGGTTGCGATTGCGCCTGAGCATGTGATTACCTCGTCAACTGCTACGGCT
ACGCTGTTGCGCACGCGCTACCCGCAAGGCACGCGCTTGCTGGCAATCGGCATGGATGGGATTCAGTCGTCGTTATTTGC
TGATCGCTATTTTGTATCAGCCGAAACCGATGTAGCAGCAGTGGTGGTTGGGGTTGATTTTAACCTGACCTATGCCCGCT
TGAAAACTGCAACCTTGGCGTTACGCGCAGGCGCAGCGTTTATTGCTACCAACAGCGACCGTACATTTCCTGCACCTGAA
GGCTTGATTCCTGGGGCTGGCTCGATTGTAGCAGCCTTGGCAGCCGCTAGCGATTGCACGCCCGAAGTGATTGGCAAACC
TGAACCAGCCATGTTCGAAGCGGCCTTGCAGTTGTTTGGAGTAACCGCCGAACAAACCTTGATGGTCGGCGATCGGTTGG
ATACCGATATTGCAGGAGCGCAGCGGGTTGGCATTGCCACGGCCTTTGTGGGCAGCGGCGTACATAGCATGCAACAAGCC
CAAGCCTGGCAACCAGCAATCGATTTGGTGGCTGATGATTTGGCAGGCATTTTGGCCTTGCTCAGGGCTGGGCGGGAGTA
G

Upstream 100 bases:

>100_bases
ATGTCATATTTCATAATCTTTAGATCGCAGTATGAACGTGTTGGCAATCCGTGGCAGTGGTACAATCGGGAGAAGTTGTT
TTTTATGGGGATTTTTCGGC

Downstream 100 bases:

>100_bases
GCCATGCATTCAATTCCAGTCATTATTGTTTCTTACAATACCCGCGATTTGTTGCGCGAATGTTTGGCAAGCTTGGCCTT
GAGTAGCCTGCCAACCCAAG

Product: HAD family hydrolase

Products: 4-nitrophenol; phosphate

Alternate protein names: NA

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MLNLKQLKLVLLDMDGVLHRGGEILPGAAELTTVLDRLGLGYACLTNNSSQLPATFARHLQDLGVAIAPEHVITSSTATA
TLLRTRYPQGTRLLAIGMDGIQSSLFADRYFVSAETDVAAVVVGVDFNLTYARLKTATLALRAGAAFIATNSDRTFPAPE
GLIPGAGSIVAALAAASDCTPEVIGKPEPAMFEAALQLFGVTAEQTLMVGDRLDTDIAGAQRVGIATAFVGSGVHSMQQA
QAWQPAIDLVADDLAGILALLRAGRE

Sequences:

>Translated_266_residues
MLNLKQLKLVLLDMDGVLHRGGEILPGAAELTTVLDRLGLGYACLTNNSSQLPATFARHLQDLGVAIAPEHVITSSTATA
TLLRTRYPQGTRLLAIGMDGIQSSLFADRYFVSAETDVAAVVVGVDFNLTYARLKTATLALRAGAAFIATNSDRTFPAPE
GLIPGAGSIVAALAAASDCTPEVIGKPEPAMFEAALQLFGVTAEQTLMVGDRLDTDIAGAQRVGIATAFVGSGVHSMQQA
QAWQPAIDLVADDLAGILALLRAGRE
>Mature_266_residues
MLNLKQLKLVLLDMDGVLHRGGEILPGAAELTTVLDRLGLGYACLTNNSSQLPATFARHLQDLGVAIAPEHVITSSTATA
TLLRTRYPQGTRLLAIGMDGIQSSLFADRYFVSAETDVAAVVVGVDFNLTYARLKTATLALRAGAAFIATNSDRTFPAPE
GLIPGAGSIVAALAAASDCTPEVIGKPEPAMFEAALQLFGVTAEQTLMVGDRLDTDIAGAQRVGIATAFVGSGVHSMQQA
QAWQPAIDLVADDLAGILALLRAGRE

Specific function: Unknown

COG id: COG0647

COG function: function code G; Predicted sugar phosphatases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. NagD family [H]

Homologues:

Organism=Homo sapiens, GI10092677, Length=249, Percent_Identity=34.5381526104418, Blast_Score=120, Evalue=9e-28,
Organism=Homo sapiens, GI108796653, Length=269, Percent_Identity=32.3420074349442, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI14149777, Length=250, Percent_Identity=30, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI269847098, Length=258, Percent_Identity=29.8449612403101, Blast_Score=85, Evalue=5e-17,
Organism=Escherichia coli, GI1786890, Length=234, Percent_Identity=32.0512820512821, Blast_Score=101, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17562458, Length=288, Percent_Identity=29.1666666666667, Blast_Score=117, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI17558880, Length=288, Percent_Identity=29.1666666666667, Blast_Score=117, Evalue=8e-27,
Organism=Caenorhabditis elegans, GI17560956, Length=292, Percent_Identity=29.1095890410959, Blast_Score=116, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI193210059, Length=262, Percent_Identity=28.6259541984733, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI86563050, Length=272, Percent_Identity=28.3088235294118, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71984613, Length=268, Percent_Identity=26.4925373134328, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17562356, Length=240, Percent_Identity=27.9166666666667, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319965, Length=241, Percent_Identity=29.4605809128631, Blast_Score=108, Evalue=6e-25,
Organism=Drosophila melanogaster, GI24666141, Length=261, Percent_Identity=31.4176245210728, Blast_Score=134, Evalue=7e-32,
Organism=Drosophila melanogaster, GI24656330, Length=291, Percent_Identity=29.8969072164948, Blast_Score=101, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24656326, Length=260, Percent_Identity=29.2307692307692, Blast_Score=100, Evalue=7e-22,
Organism=Drosophila melanogaster, GI24666137, Length=266, Percent_Identity=29.3233082706767, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI18859765, Length=279, Percent_Identity=27.9569892473118, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI19920940, Length=239, Percent_Identity=29.2887029288703, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006357
- InterPro:   IPR006354
- InterPro:   IPR023215 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: 3.1.3.41

Molecular weight: Translated: 27754; Mature: 27754

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNLKQLKLVLLDMDGVLHRGGEILPGAAELTTVLDRLGLGYACLTNNSSQLPATFARHL
CCCHHHEEEEEECCCHHHHCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHH
QDLGVAIAPEHVITSSTATATLLRTRYPQGTRLLAIGMDGIQSSLFADRYFVSAETDVAA
HHCCCEECCCHHCCCCHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHEEEECCCCEEE
VVVGVDFNLTYARLKTATLALRAGAAFIATNSDRTFPAPEGLIPGAGSIVAALAAASDCT
EEEECCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCC
PEVIGKPEPAMFEAALQLFGVTAEQTLMVGDRLDTDIAGAQRVGIATAFVGSGVHSMQQA
HHHCCCCCHHHHHHHHHHHCCCHHHEEEECCCCCCCCCCCHHHHHHHHHHHCCHHHHHHH
QAWQPAIDLVADDLAGILALLRAGRE
HHCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLNLKQLKLVLLDMDGVLHRGGEILPGAAELTTVLDRLGLGYACLTNNSSQLPATFARHL
CCCHHHEEEEEECCCHHHHCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHH
QDLGVAIAPEHVITSSTATATLLRTRYPQGTRLLAIGMDGIQSSLFADRYFVSAETDVAA
HHCCCEECCCHHCCCCHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHEEEECCCCEEE
VVVGVDFNLTYARLKTATLALRAGAAFIATNSDRTFPAPEGLIPGAGSIVAALAAASDCT
EEEECCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCC
PEVIGKPEPAMFEAALQLFGVTAEQTLMVGDRLDTDIAGAQRVGIATAFVGSGVHSMQQA
HHHCCCCCHHHHHHHHHHHCCCHHHEEEECCCCCCCCCCCHHHHHHHHHHHCCHHHHHHH
QAWQPAIDLVADDLAGILALLRAGRE
HHCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 4-nitrophenyl phosphate; H2O

Specific reaction: 4-nitrophenyl phosphate + H2O = 4-nitrophenol + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA