Click here to switch to the map view.

The map label for this gene is mtlA [H]

Identifier: 159898051

GI number: 159898051

Start: 1779331

End: 1779651

Strand: Direct

Name: mtlA [H]

Synonym: Haur_1526

Alternate gene names: 159898051

Gene position: 1779331-1779651 (Clockwise)

Preceding gene: 159898050

Following gene: 159898052

Centisome position: 28.04

GC content: 48.91

Gene sequence:

>321_bases
ATGGCTCAATCAATTGCCGCTGCCGATGTTACAACGATTGTGTTTGCCTGTGAAGCAGGCATTGGCTCAAGTTTTATGGG
TGTTACGGCACTCAAAAAGAAACTCAAACAAGCCAATTTGAGCATCACGGTGGTGCATAAATCGGTGCGCTCGTTGCCAA
CCGATGCCAAGCTGGTGTTGGTGCACAAAGGCTTAGCCGATTTTGCGCGGAAGCAAGCGCCTAATGCCGTCGTGATTGCC
TTTACCCAATTCCTCAATGATCCTGTGTTTGATCAAGTGGTTCAAAGCTTGCAGGATGGCACTGATCTTGTGGAGGCCTA
A

Upstream 100 bases:

>100_bases
CGAAGAAACTGTGGCAGATGAGCAAACCAGTTCAGAAATGACTGGCACCGCTGCAACCGCCCACTAATTGCGCTTGAATC
TCAACTGAAGGAGGTATGTC

Downstream 100 bases:

>100_bases
AATGGCAATCTTATCGAGCGAAACGATTCGGCTAGGAGCTAGCGCTGCTAGCAAACAAGAGGCGATTCAGCAGGCCGGAG
CGTTGTTAGTTGCCAGTGGT

Product: phosphotransferase system lactose/cellobiose-specific IIB subunit

Products: NA

Alternate protein names: EIICB-Mtl; EII-Mtl; Mannitol permease IIC component; PTS system mannitol-specific EIIC component; Mannitol-specific phosphotransferase enzyme IIB component; PTS system mannitol-specific EIIB component [H]

Number of amino acids: Translated: 106; Mature: 105

Protein sequence:

>106_residues
MAQSIAAADVTTIVFACEAGIGSSFMGVTALKKKLKQANLSITVVHKSVRSLPTDAKLVLVHKGLADFARKQAPNAVVIA
FTQFLNDPVFDQVVQSLQDGTDLVEA

Sequences:

>Translated_106_residues
MAQSIAAADVTTIVFACEAGIGSSFMGVTALKKKLKQANLSITVVHKSVRSLPTDAKLVLVHKGLADFARKQAPNAVVIA
FTQFLNDPVFDQVVQSLQDGTDLVEA
>Mature_105_residues
AQSIAAADVTTIVFACEAGIGSSFMGVTALKKKLKQANLSITVVHKSVRSLPTDAKLVLVHKGLADFARKQAPNAVVIAF
TQFLNDPVFDQVVQSLQDGTDLVEA

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG2213

COG function: function code G; Phosphotransferase system, mannitol-specific IIBC component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1790027, Length=104, Percent_Identity=37.5, Blast_Score=73, Evalue=4e-15,
Organism=Escherichia coli, GI1789301, Length=94, Percent_Identity=32.9787234042553, Blast_Score=62, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013011
- InterPro:   IPR003501
- InterPro:   IPR003352
- InterPro:   IPR013014
- InterPro:   IPR004718 [H]

Pfam domain/function: PF02378 PTS_EIIC; PF02302 PTS_IIB [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 11227; Mature: 11096

Theoretical pI: Translated: 8.52; Mature: 8.52

Prosite motif: PS51099 PTS_EIIB_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQSIAAADVTTIVFACEAGIGSSFMGVTALKKKLKQANLSITVVHKSVRSLPTDAKLVL
CCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEEEHHHHCCCCCCEEEE
VHKGLADFARKQAPNAVVIAFTQFLNDPVFDQVVQSLQDGTDLVEA
EECCHHHHHHHCCCCEEEEHHHHHHCCHHHHHHHHHHHCCHHHHCC
>Mature Secondary Structure 
AQSIAAADVTTIVFACEAGIGSSFMGVTALKKKLKQANLSITVVHKSVRSLPTDAKLVL
CCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEEEHHHHCCCCCCEEEE
VHKGLADFARKQAPNAVVIAFTQFLNDPVFDQVVQSLQDGTDLVEA
EECCHHHHHHHCCCCEEEEHHHHHHCCHHHHHHHHHHHCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]