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The map label for this gene is mtlA [H]

Identifier: 159898050

GI number: 159898050

Start: 1778227

End: 1779297

Strand: Direct

Name: mtlA [H]

Synonym: Haur_1525

Alternate gene names: 159898050

Gene position: 1778227-1779297 (Clockwise)

Preceding gene: 159898049

Following gene: 159898051

Centisome position: 28.02

GC content: 51.63

Gene sequence:

>1071_bases
ATGCGACAGCATATTCAGCGCTTCGGCAGCTTCTTGGCTGCAATGGTTGTTCCCAATATCGGTGCGTTCATCGCTTGGGG
CTTAATCACCGCTCTGTTCATCCCAACTGGTTGGATTCCGAACGAAACTTTTGCCAAGCTCGTTGGCCCAATGATTACTT
ACCTTTTGCCCACCTTGATTGGTTATACTGGCGGTAAGATGATTCACGATACCCGTGGCGGGGTGGTTGGGGCCGCCGCA
ACCATGGGTGTAATCGTCGGAGCCGATATTCCAATGTTTATCGGGGCCATGGTCATGGGGCCACTTGGCGGCTACCTGAT
GAAGAAAATTGACGAATTCCTCGAAGATCGCGTGCCAACTGGCTTTGAAATGTTGGTCAATAACTTCTCGGCAGGCTTCC
TTGTGATGGGCTTGGTGCTATTGGCGAATGCGGCGATTGGCCCTGTTGTCCAAGTGTTAAGTGAGGGCTTAGGCTCTGGC
GTTCAATTCCTGATCGACTCACGCTTGTTGCCTGTGGCCGATATTATTATTGAACCAGCCAAAGTACTCTTCCTCAATAA
CGCCATCAATCACGGGATTCTTGGCCCCTTAGGCGTGGCTGAAGTTGGCGAAAATGGTAAAGCGATTCACTTTTTGCTCG
AAAGTAACCCCGGCCCTGGCTTAGGCTTGCTCTTGGCCTTCTGGTTTGCTGGCAAAGGCAACCTCAAAGAATCAGCACCA
GGTGCTGCAGTAATTCACTTCCTCGGTGGGATTCACGAAATCTATTTCCCCTACATTTTGGCTCGTCCTGTGATGATTGT
GGCAATGTGGGCTGGCGGGATCTTAGCCGACCTGTGGTTTGTGATTTTTGATGCAGGTTTGGTTGCTACGCCATCACCTG
GCTCGATCTTTGCCTACTTGGCGGTTATTCCACGTGGCGGTCACTTTGCGGTCTTAGGTGGGGTTTTCGTCGGGATTGTT
GGCTCGTTTGTGGCTGGCTCGATGTTGCTCAAACTCTTCCCGGGCGAAGAAACTGTGGCAGATGAGCAAACCAGTTCAGA
AATGACTGGCACCGCTGCAACCGCCCACTAA

Upstream 100 bases:

>100_bases
GCGCAGATAACAACCCGGGCGTTAGCTGACGAACCACCATTCTGAATCCACGGGGCAATCAACGACGATTAACAATGACT
TCAAAGGAGAAACGCCCATC

Downstream 100 bases:

>100_bases
TTGCGCTTGAATCTCAACTGAAGGAGGTATGTCATGGCTCAATCAATTGCCGCTGCCGATGTTACAACGATTGTGTTTGC
CTGTGAAGCAGGCATTGGCT

Product: PTS system, mannitol-specific IIC subunit

Products: NA

Alternate protein names: EIICB-Mtl; EII-Mtl; Mannitol permease IIC component; PTS system mannitol-specific EIIC component; Mannitol-specific phosphotransferase enzyme IIB component; PTS system mannitol-specific EIIB component [H]

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MRQHIQRFGSFLAAMVVPNIGAFIAWGLITALFIPTGWIPNETFAKLVGPMITYLLPTLIGYTGGKMIHDTRGGVVGAAA
TMGVIVGADIPMFIGAMVMGPLGGYLMKKIDEFLEDRVPTGFEMLVNNFSAGFLVMGLVLLANAAIGPVVQVLSEGLGSG
VQFLIDSRLLPVADIIIEPAKVLFLNNAINHGILGPLGVAEVGENGKAIHFLLESNPGPGLGLLLAFWFAGKGNLKESAP
GAAVIHFLGGIHEIYFPYILARPVMIVAMWAGGILADLWFVIFDAGLVATPSPGSIFAYLAVIPRGGHFAVLGGVFVGIV
GSFVAGSMLLKLFPGEETVADEQTSSEMTGTAATAH

Sequences:

>Translated_356_residues
MRQHIQRFGSFLAAMVVPNIGAFIAWGLITALFIPTGWIPNETFAKLVGPMITYLLPTLIGYTGGKMIHDTRGGVVGAAA
TMGVIVGADIPMFIGAMVMGPLGGYLMKKIDEFLEDRVPTGFEMLVNNFSAGFLVMGLVLLANAAIGPVVQVLSEGLGSG
VQFLIDSRLLPVADIIIEPAKVLFLNNAINHGILGPLGVAEVGENGKAIHFLLESNPGPGLGLLLAFWFAGKGNLKESAP
GAAVIHFLGGIHEIYFPYILARPVMIVAMWAGGILADLWFVIFDAGLVATPSPGSIFAYLAVIPRGGHFAVLGGVFVGIV
GSFVAGSMLLKLFPGEETVADEQTSSEMTGTAATAH
>Mature_356_residues
MRQHIQRFGSFLAAMVVPNIGAFIAWGLITALFIPTGWIPNETFAKLVGPMITYLLPTLIGYTGGKMIHDTRGGVVGAAA
TMGVIVGADIPMFIGAMVMGPLGGYLMKKIDEFLEDRVPTGFEMLVNNFSAGFLVMGLVLLANAAIGPVVQVLSEGLGSG
VQFLIDSRLLPVADIIIEPAKVLFLNNAINHGILGPLGVAEVGENGKAIHFLLESNPGPGLGLLLAFWFAGKGNLKESAP
GAAVIHFLGGIHEIYFPYILARPVMIVAMWAGGILADLWFVIFDAGLVATPSPGSIFAYLAVIPRGGHFAVLGGVFVGIV
GSFVAGSMLLKLFPGEETVADEQTSSEMTGTAATAH

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG2213

COG function: function code G; Phosphotransferase system, mannitol-specific IIBC component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1789301, Length=355, Percent_Identity=55.2112676056338, Blast_Score=387, Evalue=1e-109,
Organism=Escherichia coli, GI1790027, Length=356, Percent_Identity=56.4606741573034, Blast_Score=386, Evalue=1e-108,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013011
- InterPro:   IPR003501
- InterPro:   IPR003352
- InterPro:   IPR013014
- InterPro:   IPR004718 [H]

Pfam domain/function: PF02378 PTS_EIIC; PF02302 PTS_IIB [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 37274; Mature: 37274

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: PS51104 PTS_EIIC_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQHIQRFGSFLAAMVVPNIGAFIAWGLITALFIPTGWIPNETFAKLVGPMITYLLPTLI
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
GYTGGKMIHDTRGGVVGAAATMGVIVGADIPMFIGAMVMGPLGGYLMKKIDEFLEDRVPT
HCCCCCEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GFEMLVNNFSAGFLVMGLVLLANAAIGPVVQVLSEGLGSGVQFLIDSRLLPVADIIIEPA
HHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHCCH
KVLFLNNAINHGILGPLGVAEVGENGKAIHFLLESNPGPGLGLLLAFWFAGKGNLKESAP
HHEEEHHHHCCCCCCCCCHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCC
GAAVIHFLGGIHEIYFPYILARPVMIVAMWAGGILADLWFVIFDAGLVATPSPGSIFAYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHEEEE
AVIPRGGHFAVLGGVFVGIVGSFVAGSMLLKLFPGEETVADEQTSSEMTGTAATAH
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCHHHHHHCCCCCCCC
>Mature Secondary Structure
MRQHIQRFGSFLAAMVVPNIGAFIAWGLITALFIPTGWIPNETFAKLVGPMITYLLPTLI
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
GYTGGKMIHDTRGGVVGAAATMGVIVGADIPMFIGAMVMGPLGGYLMKKIDEFLEDRVPT
HCCCCCEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GFEMLVNNFSAGFLVMGLVLLANAAIGPVVQVLSEGLGSGVQFLIDSRLLPVADIIIEPA
HHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHCCH
KVLFLNNAINHGILGPLGVAEVGENGKAIHFLLESNPGPGLGLLLAFWFAGKGNLKESAP
HHEEEHHHHCCCCCCCCCHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCC
GAAVIHFLGGIHEIYFPYILARPVMIVAMWAGGILADLWFVIFDAGLVATPSPGSIFAYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHEEEE
AVIPRGGHFAVLGGVFVGIVGSFVAGSMLLKLFPGEETVADEQTSSEMTGTAATAH
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8824601 [H]