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The map label for this gene is yuxL [H]

Identifier: 159897952

GI number: 159897952

Start: 1646623

End: 1648671

Strand: Reverse

Name: yuxL [H]

Synonym: Haur_1427

Alternate gene names: 159897952

Gene position: 1648671-1646623 (Counterclockwise)

Preceding gene: 159897957

Following gene: 159897948

Centisome position: 25.98

GC content: 52.86

Gene sequence:

>2049_bases
ATGGCCGAGTTGCGCAACTGGCAAGCCACGAGTCTGTTAGAGCTACGTTTTATCTCCGATGCCCAAATTTCGCCCAACGG
CGAGCAAATTGCCTTTGTGGAAACCTGGATCGAGGAAACCACCAACAAGAGTGGCACTCGCAAGCCCGATTATCGTTCAG
CAATTATGTTAATTCAGGCCGATGGTGGCATACCGCAACGCATGACGTTCAGCGTTTCAGGTCGCGATAGCTCGCCACGC
TGGTCGCCCGATGGCAGTAAATTGGCCTTTATCTCAACTCGTGATGCAGGCGTGGCTCAACTGTTTGTGCTCGATTTGGC
TCGTGGTGGCGAGGCCCAGCAACTCACCAGCCTTGGTTATGGTGTGGCCGAAATCAACTGGCGCCCTGATAGCCAAGCCT
TGGCGTTTATCTCGCGCGGAGCCAAAGCCAAAGCGCAAACCCATGTCGAAAGCCTGCGCGACGAAAAAATTATCGAACGC
TTGCCATTCAAATTCGATGGCGTGGGCTATTTACAGCCAGAATACGCGCAAATTTGGCTGGTTGAATTAGGGCAAGAACC
AAACCAAATCACCGATCAAGCCTTTGATCACGCTGATCCGGCTTGGTCGCCTGATGGTAGCGAGTTGGCTTTTATCACGG
TTTCGCGGGCCGAATTAGAACACACCCGCCAAGCTGATATGTACCTACTAAATGTTGCAGCTGGTACATCGCGCTGTTTA
ACTAATGCGCTGGGTCCGGTCTATCACCCAACCTGGTCGCCCGATGGCAGCCAAATCGCCTATATCGGCCATGATCAACA
TACGGGCAATGCATCAAATGAGGCTTTGTGGTGTGTTAGTCGAGCGGGCGGTGATGCCCGTTTGCTCAGTGTTGGCTTTG
AATATGGGCTTGAAAATAGCGTGATCAGCGATGCACGCATTGGGCGCTTTCCTTATCGGCCTTATTGGCGCGATAATGGC
ATTTACTGTTTGGCAACCCGTGCCGCCCGCACCCGTGCTTATCGCTACAGCGACGGCGCGATGCATGAACTTACGCCTGA
GGATAACCCAAGCATTTCGGGCTACAGCCAATCGTTGAACAAGCGCACTGCCTTCACCGCTGGCACTGCCACCCAACTCG
AAGCGCTGTATATGGGCGATGCTGATGGCAGTATTCATCTGCTCTACGACCCCAATGCTGCATTACTCACCAGCATCCAA
ACCATCGAGCCAGAACGCTTTACCTACAATAGCTTCGATGGCTTGGAGATCGAAGGCTGGGTGATCAAGCCTGTCGGATT
CAGCCAAGGCCAGCAATATCCCTCGTTGTTGTATATTCATGGTGGCCCGCATAGCGCCTATGGTCACAATTTTATGCACG
AATTTCAGGTGCTGGCGGCGGCTGGCTATGGCGTGATTTACACCAATCCACGCGGTGGCACAGGCTATGGTCAGCGCTTC
CGCGCGTTGGTACGCCAAGATTTTGGCGGCGATGATTATCGCGATCTCATGGCTGCTGCCGATTTGGCCGAAACCTGGGA
TTGGATCGACAGCAAACGGATGGGTGTGCTTGGTGGCTCGTATGGCGGCTATATGACCAACTGGATCATCAGCCATACCG
AGCGCTTTGCCGCCGCCAATACCCAACGCTGTATCTCCAATTTAATGAGCTTTTTCGGCACATCGGATATTGGGCCATAT
TTCGGCGAAGATGAATTCGGTGGCAAGCCTTGGGCTGATATCGATAAATTTATGGAACGCTCACCGATTCGTTATGTCAA
TTCAATTAACACCCCATTGTTAATTTTGCATTCCGATGAGGACCATCGCTGCCCAGTCGAGCAAGCCGAGCAACTGTATA
CCGCGCTCAAAGTGCTGGATAAACCTGTGCGTTTTGTCCGCTTCCCGCGCGAAGGCCACGAACTTTCACGTAGCGGCGAG
CCATTGCATCGCATCGCACGAATCGAATATATTCTGGATTGGTTCGGCCATTATTTGCAAGGCCACGAACTCAAGCCCGC
TGATCACTTCCGGCGCAGCGTTGCTGGCGAATGGCAAAGCCGCCAATAA

Upstream 100 bases:

>100_bases
GATATTCATGCTGAAATGCTTCCTCCCGCTTGCTGAGCGGGTTAGGGGGTGAGGGCTTGCAGATTAACGAATCATTGCAT
ATAGAGAATAGGAATCAAGC

Downstream 100 bases:

>100_bases
TTTCACGATCAGATTGTTTTCAAGGCCGTTGCCACATTTAGGCAGCGGCTTTTTGCTGATTTTGACCACGATACCAATTA
ATCGTTGTCTGCAACGCTTG

Product: peptidase S9 prolyl oligopeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 682; Mature: 681

Protein sequence:

>682_residues
MAELRNWQATSLLELRFISDAQISPNGEQIAFVETWIEETTNKSGTRKPDYRSAIMLIQADGGIPQRMTFSVSGRDSSPR
WSPDGSKLAFISTRDAGVAQLFVLDLARGGEAQQLTSLGYGVAEINWRPDSQALAFISRGAKAKAQTHVESLRDEKIIER
LPFKFDGVGYLQPEYAQIWLVELGQEPNQITDQAFDHADPAWSPDGSELAFITVSRAELEHTRQADMYLLNVAAGTSRCL
TNALGPVYHPTWSPDGSQIAYIGHDQHTGNASNEALWCVSRAGGDARLLSVGFEYGLENSVISDARIGRFPYRPYWRDNG
IYCLATRAARTRAYRYSDGAMHELTPEDNPSISGYSQSLNKRTAFTAGTATQLEALYMGDADGSIHLLYDPNAALLTSIQ
TIEPERFTYNSFDGLEIEGWVIKPVGFSQGQQYPSLLYIHGGPHSAYGHNFMHEFQVLAAAGYGVIYTNPRGGTGYGQRF
RALVRQDFGGDDYRDLMAAADLAETWDWIDSKRMGVLGGSYGGYMTNWIISHTERFAAANTQRCISNLMSFFGTSDIGPY
FGEDEFGGKPWADIDKFMERSPIRYVNSINTPLLILHSDEDHRCPVEQAEQLYTALKVLDKPVRFVRFPREGHELSRSGE
PLHRIARIEYILDWFGHYLQGHELKPADHFRRSVAGEWQSRQ

Sequences:

>Translated_682_residues
MAELRNWQATSLLELRFISDAQISPNGEQIAFVETWIEETTNKSGTRKPDYRSAIMLIQADGGIPQRMTFSVSGRDSSPR
WSPDGSKLAFISTRDAGVAQLFVLDLARGGEAQQLTSLGYGVAEINWRPDSQALAFISRGAKAKAQTHVESLRDEKIIER
LPFKFDGVGYLQPEYAQIWLVELGQEPNQITDQAFDHADPAWSPDGSELAFITVSRAELEHTRQADMYLLNVAAGTSRCL
TNALGPVYHPTWSPDGSQIAYIGHDQHTGNASNEALWCVSRAGGDARLLSVGFEYGLENSVISDARIGRFPYRPYWRDNG
IYCLATRAARTRAYRYSDGAMHELTPEDNPSISGYSQSLNKRTAFTAGTATQLEALYMGDADGSIHLLYDPNAALLTSIQ
TIEPERFTYNSFDGLEIEGWVIKPVGFSQGQQYPSLLYIHGGPHSAYGHNFMHEFQVLAAAGYGVIYTNPRGGTGYGQRF
RALVRQDFGGDDYRDLMAAADLAETWDWIDSKRMGVLGGSYGGYMTNWIISHTERFAAANTQRCISNLMSFFGTSDIGPY
FGEDEFGGKPWADIDKFMERSPIRYVNSINTPLLILHSDEDHRCPVEQAEQLYTALKVLDKPVRFVRFPREGHELSRSGE
PLHRIARIEYILDWFGHYLQGHELKPADHFRRSVAGEWQSRQ
>Mature_681_residues
AELRNWQATSLLELRFISDAQISPNGEQIAFVETWIEETTNKSGTRKPDYRSAIMLIQADGGIPQRMTFSVSGRDSSPRW
SPDGSKLAFISTRDAGVAQLFVLDLARGGEAQQLTSLGYGVAEINWRPDSQALAFISRGAKAKAQTHVESLRDEKIIERL
PFKFDGVGYLQPEYAQIWLVELGQEPNQITDQAFDHADPAWSPDGSELAFITVSRAELEHTRQADMYLLNVAAGTSRCLT
NALGPVYHPTWSPDGSQIAYIGHDQHTGNASNEALWCVSRAGGDARLLSVGFEYGLENSVISDARIGRFPYRPYWRDNGI
YCLATRAARTRAYRYSDGAMHELTPEDNPSISGYSQSLNKRTAFTAGTATQLEALYMGDADGSIHLLYDPNAALLTSIQT
IEPERFTYNSFDGLEIEGWVIKPVGFSQGQQYPSLLYIHGGPHSAYGHNFMHEFQVLAAAGYGVIYTNPRGGTGYGQRFR
ALVRQDFGGDDYRDLMAAADLAETWDWIDSKRMGVLGGSYGGYMTNWIISHTERFAAANTQRCISNLMSFFGTSDIGPYF
GEDEFGGKPWADIDKFMERSPIRYVNSINTPLLILHSDEDHRCPVEQAEQLYTALKVLDKPVRFVRFPREGHELSRSGEP
LHRIARIEYILDWFGHYLQGHELKPADHFRRSVAGEWQSRQ

Specific function: Involved In The Tonb-Independent Uptake Of Group A Colicins (Colicins A, E1, E2, E3 And K). Necessary For The Colicins To Reach Their Respective Targets After Initial Binding To The Bacteria. [C]

COG id: COG1506

COG function: function code E; Dipeptidyl aminopeptidases/acylaminoacyl-peptidases

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9B family [H]

Homologues:

Organism=Homo sapiens, GI23510451, Length=249, Percent_Identity=29.718875502008, Blast_Score=124, Evalue=3e-28,
Organism=Homo sapiens, GI37577089, Length=248, Percent_Identity=27.0161290322581, Blast_Score=75, Evalue=3e-13,
Organism=Homo sapiens, GI18450280, Length=252, Percent_Identity=26.984126984127, Blast_Score=75, Evalue=3e-13,
Organism=Homo sapiens, GI194394146, Length=251, Percent_Identity=24.7011952191235, Blast_Score=72, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17552908, Length=244, Percent_Identity=26.6393442622951, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI25144537, Length=228, Percent_Identity=28.0701754385965, Blast_Score=86, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI25144540, Length=228, Percent_Identity=28.0701754385965, Blast_Score=86, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI25149159, Length=233, Percent_Identity=27.0386266094421, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45551969, Length=242, Percent_Identity=27.6859504132231, Blast_Score=79, Evalue=9e-15,
Organism=Drosophila melanogaster, GI45550825, Length=242, Percent_Identity=27.6859504132231, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI45553511, Length=242, Percent_Identity=27.6859504132231, Blast_Score=79, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042
- InterPro:   IPR011659
- InterPro:   IPR001375 [H]

Pfam domain/function: PF07676 PD40; PF00326 Peptidase_S9 [H]

EC number: NA

Molecular weight: Translated: 76360; Mature: 76229

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAELRNWQATSLLELRFISDAQISPNGEQIAFVETWIEETTNKSGTRKPDYRSAIMLIQA
CCCCCCCCCCEEEEEEEECCCEECCCCCEEEEHHHHHHHHCCCCCCCCCCCCEEEEEEEC
DGGIPQRMTFSVSGRDSSPRWSPDGSKLAFISTRDAGVAQLFVLDLARGGEAQQLTSLGY
CCCCCCEEEEEECCCCCCCCCCCCCCEEEEEEECCCCHHEEEEEHHHCCCCHHHHHHHCC
GVAEINWRPDSQALAFISRGAKAKAQTHVESLRDEKIIERLPFKFDGVGYLQPEYAQIWL
CEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHEEEE
VELGQEPNQITDQAFDHADPAWSPDGSELAFITVSRAELEHTRQADMYLLNVAAGTSRCL
EECCCCCCHHHHHHHHCCCCCCCCCCCEEEEEEEEHHHHHHHHCCCEEEEEECCCCHHHH
TNALGPVYHPTWSPDGSQIAYIGHDQHTGNASNEALWCVSRAGGDARLLSVGFEYGLENS
HHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCEEEEEECCCCCEEEEEEHHHHCCCCC
VISDARIGRFPYRPYWRDNGIYCLATRAARTRAYRYSDGAMHELTPEDNPSISGYSQSLN
CCCCCCCCCCCCCCEECCCCEEEEEECHHHHHEEECCCCCCCCCCCCCCCCCCCHHHHHC
KRTAFTAGTATQLEALYMGDADGSIHLLYDPNAALLTSIQTIEPERFTYNSFDGLEIEGW
CCCEEECCCHHHEEEEEECCCCCEEEEEECCCHHHHHHHHHCCCCCEEECCCCCEEECCE
VIKPVGFSQGQQYPSLLYIHGGPHSAYGHNFMHEFQVLAAAGYGVIYTNPRGGTGYGQRF
EEECCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCHHHHH
RALVRQDFGGDDYRDLMAAADLAETWDWIDSKRMGVLGGSYGGYMTNWIISHTERFAAAN
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHCC
TQRCISNLMSFFGTSDIGPYFGEDEFGGKPWADIDKFMERSPIRYVNSINTPLLILHSDE
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHCCCCCEEEEECCC
DHRCPVEQAEQLYTALKVLDKPVRFVRFPREGHELSRSGEPLHRIARIEYILDWFGHYLQ
CCCCCHHHHHHHHHHHHHHHCCHHEEECCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHC
GHELKPADHFRRSVAGEWQSRQ
CCCCCCHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AELRNWQATSLLELRFISDAQISPNGEQIAFVETWIEETTNKSGTRKPDYRSAIMLIQA
CCCCCCCCCEEEEEEEECCCEECCCCCEEEEHHHHHHHHCCCCCCCCCCCCEEEEEEEC
DGGIPQRMTFSVSGRDSSPRWSPDGSKLAFISTRDAGVAQLFVLDLARGGEAQQLTSLGY
CCCCCCEEEEEECCCCCCCCCCCCCCEEEEEEECCCCHHEEEEEHHHCCCCHHHHHHHCC
GVAEINWRPDSQALAFISRGAKAKAQTHVESLRDEKIIERLPFKFDGVGYLQPEYAQIWL
CEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHEEEE
VELGQEPNQITDQAFDHADPAWSPDGSELAFITVSRAELEHTRQADMYLLNVAAGTSRCL
EECCCCCCHHHHHHHHCCCCCCCCCCCEEEEEEEEHHHHHHHHCCCEEEEEECCCCHHHH
TNALGPVYHPTWSPDGSQIAYIGHDQHTGNASNEALWCVSRAGGDARLLSVGFEYGLENS
HHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCEEEEEECCCCCEEEEEEHHHHCCCCC
VISDARIGRFPYRPYWRDNGIYCLATRAARTRAYRYSDGAMHELTPEDNPSISGYSQSLN
CCCCCCCCCCCCCCEECCCCEEEEEECHHHHHEEECCCCCCCCCCCCCCCCCCCHHHHHC
KRTAFTAGTATQLEALYMGDADGSIHLLYDPNAALLTSIQTIEPERFTYNSFDGLEIEGW
CCCEEECCCHHHEEEEEECCCCCEEEEEECCCHHHHHHHHHCCCCCEEECCCCCEEECCE
VIKPVGFSQGQQYPSLLYIHGGPHSAYGHNFMHEFQVLAAAGYGVIYTNPRGGTGYGQRF
EEECCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCHHHHH
RALVRQDFGGDDYRDLMAAADLAETWDWIDSKRMGVLGGSYGGYMTNWIISHTERFAAAN
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHCC
TQRCISNLMSFFGTSDIGPYFGEDEFGGKPWADIDKFMERSPIRYVNSINTPLLILHSDE
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHCCCCCEEEEECCC
DHRCPVEQAEQLYTALKVLDKPVRFVRFPREGHELSRSGEPLHRIARIEYILDWFGHYLQ
CCCCCHHHHHHHHHHHHHHHCCHHEEECCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHC
GHELKPADHFRRSVAGEWQSRQ
CCCCCCHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 3098560 [H]