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The map label for this gene is rsbRA [H]

Identifier: 159897846

GI number: 159897846

Start: 1526034

End: 1526894

Strand: Reverse

Name: rsbRA [H]

Synonym: Haur_1317

Alternate gene names: 159897846

Gene position: 1526894-1526034 (Counterclockwise)

Preceding gene: 159897848

Following gene: 159897845

Centisome position: 24.06

GC content: 53.43

Gene sequence:

>861_bases
ATGTTGCCAGAAACACTTATCCAACAGATGAGCCATGGCTGGGTTCACGCCCCGATTGCCTCGCTGATTTATCATCGCAA
TGGCCGCGCCGAATTGCTCAACCGCGCCGGAATGGAGTTATTGCAATATCAGCCGGAAGAGGCTGCCCTAGCTCAACAAC
ATTATAATCTGCATCGAGACCCTTCACTCCAAGCGCCGCTAACCAAAAGTGCCATTGCCTCAGCTTTTGAGGGCAAAAAA
ACCCGCATCGGCGAGTTGGATTATGAGTTGCTAAATGTGCAGGCGCGGCCTTCTGGCAAACATATTGTGGCGCGACTCAA
TCTGGCTCCGCTACGGGTCGAAGCCAAAACTGGCGAGTATATTGTGGCATTTTTTACCGATATCACGCCCCAAGTAACCC
TGCGCCGCGAACTCGATAGCCGCAAGCACGAAATTCAACAGGCCGAACAACAACAAGAAGCGCTACGAGCCGAAATCGAA
GCTCGTTCAGCTCCGGTTGTGCCAGTGTTGCCCGGCATTTTGGTGTTGCCCTTGGTTGGCGCGATCGATTCACGCCGCGC
CGAATATGTCTTGAATTGTTTGCTCGAAGCCGCCTCAGAGCATAGCGCCGATACGCTGTTGCTCGATGTTACGGGCATTC
CGGTGGTCGATACGGCTGTAGCCAATTATCTGCTGCAAGCCATCAAAGCGCTCAAATTGCTTGGCACCGACACCATTGTG
GTTGGCATCAGCCCCGAAATTGCCCAAACCTTGGTGCAATTGGGCCTGCGGCTGGAAGATATTACCACTCGCGCCGATTT
ACAAAGTGGCTTGCAGACCGCCCTTCGTCGCCAAGGCCAAATTATTCGTGCTCGTTCGTGA

Upstream 100 bases:

>100_bases
ACTCGTGAATTTGAAACAATTCTTCCCACCACATTCGCTGTTCATCCATTGCCAACCTCGCTTATAATCTACAAACAATG
CCAGTGATTGAGGGTCGCAT

Downstream 100 bases:

>100_bases
GGTGCGCCCATGGCTTCTAGCTTAAATACACTCATTCGCAGCAGCGCTTGGTCGGTTATGTCAATCGGTTCAGCCATTTA
CGATCAAACAGGCAAGGTCA

Product: anti-sigma-factor antagonist

Products: NA

Alternate protein names: Stressosome protein rsbRA [H]

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MLPETLIQQMSHGWVHAPIASLIYHRNGRAELLNRAGMELLQYQPEEAALAQQHYNLHRDPSLQAPLTKSAIASAFEGKK
TRIGELDYELLNVQARPSGKHIVARLNLAPLRVEAKTGEYIVAFFTDITPQVTLRRELDSRKHEIQQAEQQQEALRAEIE
ARSAPVVPVLPGILVLPLVGAIDSRRAEYVLNCLLEAASEHSADTLLLDVTGIPVVDTAVANYLLQAIKALKLLGTDTIV
VGISPEIAQTLVQLGLRLEDITTRADLQSGLQTALRRQGQIIRARS

Sequences:

>Translated_286_residues
MLPETLIQQMSHGWVHAPIASLIYHRNGRAELLNRAGMELLQYQPEEAALAQQHYNLHRDPSLQAPLTKSAIASAFEGKK
TRIGELDYELLNVQARPSGKHIVARLNLAPLRVEAKTGEYIVAFFTDITPQVTLRRELDSRKHEIQQAEQQQEALRAEIE
ARSAPVVPVLPGILVLPLVGAIDSRRAEYVLNCLLEAASEHSADTLLLDVTGIPVVDTAVANYLLQAIKALKLLGTDTIV
VGISPEIAQTLVQLGLRLEDITTRADLQSGLQTALRRQGQIIRARS
>Mature_286_residues
MLPETLIQQMSHGWVHAPIASLIYHRNGRAELLNRAGMELLQYQPEEAALAQQHYNLHRDPSLQAPLTKSAIASAFEGKK
TRIGELDYELLNVQARPSGKHIVARLNLAPLRVEAKTGEYIVAFFTDITPQVTLRRELDSRKHEIQQAEQQQEALRAEIE
ARSAPVVPVLPGILVLPLVGAIDSRRAEYVLNCLLEAASEHSADTLLLDVTGIPVVDTAVANYLLQAIKALKLLGTDTIV
VGISPEIAQTLVQLGLRLEDITTRADLQSGLQTALRRQGQIIRARS

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014792
- InterPro:   IPR002645 [H]

Pfam domain/function: PF08678 Rsbr_N; PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 31523; Mature: 31523

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPETLIQQMSHGWVHAPIASLIYHRNGRAELLNRAGMELLQYQPEEAALAQQHYNLHRD
CCHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCC
PSLQAPLTKSAIASAFEGKKTRIGELDYELLNVQARPSGKHIVARLNLAPLRVEAKTGEY
CCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHEEECCCCCCEEEEEECCCEEEEEECCCCE
IVAFFTDITPQVTLRRELDSRKHEIQQAEQQQEALRAEIEARSAPVVPVLPGILVLPLVG
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
AIDSRRAEYVLNCLLEAASEHSADTLLLDVTGIPVVDTAVANYLLQAIKALKLLGTDTIV
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCEEE
VGISPEIAQTLVQLGLRLEDITTRADLQSGLQTALRRQGQIIRARS
EECCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCC
>Mature Secondary Structure
MLPETLIQQMSHGWVHAPIASLIYHRNGRAELLNRAGMELLQYQPEEAALAQQHYNLHRD
CCHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCC
PSLQAPLTKSAIASAFEGKKTRIGELDYELLNVQARPSGKHIVARLNLAPLRVEAKTGEY
CCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHEEECCCCCCEEEEEECCCEEEEEECCCCE
IVAFFTDITPQVTLRRELDSRKHEIQQAEQQQEALRAEIEARSAPVVPVLPGILVLPLVG
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
AIDSRRAEYVLNCLLEAASEHSADTLLLDVTGIPVVDTAVANYLLQAIKALKLLGTDTIV
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCEEE
VGISPEIAQTLVQLGLRLEDITTRADLQSGLQTALRRQGQIIRARS
EECCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 11157946; 10329124 [H]