Click here to switch to the map view.

The map label for this gene is rsbRA [H]

Identifier: 159897845

GI number: 159897845

Start: 1525170

End: 1526024

Strand: Reverse

Name: rsbRA [H]

Synonym: Haur_1316

Alternate gene names: 159897845

Gene position: 1526024-1525170 (Counterclockwise)

Preceding gene: 159897846

Following gene: 159897844

Centisome position: 24.04

GC content: 49.71

Gene sequence:

>855_bases
ATGGCTTCTAGCTTAAATACACTCATTCGCAGCAGCGCTTGGTCGGTTATGTCAATCGGTTCAGCCATTTACGATCAAAC
AGGCAAGGTCATTTATACCAATACTGCCTTGCGCCGAATTTTCAATCTCAGCCCAGCCGAAATGTTGGAACTCCAAGAAC
ATTACAATTTATTTGATGATCCTTCCTTGGCGACCCCTGAACTGCAAGCAGATTTGAAACGGGCATTTGCTGGCGAAGAA
GTTTTCTTGCCAATTTTAGATTATGTGATTGTTGATGCCCATGGCCAGCCGAGCAACCGCCATTTAGCCGCACGCTTTTT
GCTCAAGCCTGTGGGCGATGCCACGCCACCAGAATATGTCGTGGGCTATTTCCACGATGTCAGCGAATCGCTCGAGTTAG
AAGCCCAAATTAGCGCTCGGCGTGATGAAATTGATCGCATGAGCCAACAAGATTCGTTGCTCAAAGCCGAAATTGCCGCC
CGTGCTGTGCCAGTTGTGCCAATTCTGCCAGGAATTTTAGTATTGCCCTTGGTTGGTGGCATCGACCCAATGCAAGCCGA
CCAAATTATTACCGCCTTGTTGCAGGCCAGCTCGCGCAGCAACGCCGATACCGTGATCTTGGATTTAACCGGCGTGCCGG
TGGTGGATACGGCGGTGGCAAACTACATTTTGCAGGCTATCAATGCGCTTAAATTGCTTGGCACTGAAACAATTGTAGTC
GGCATTAGCAACGAAATCGCCCAAACCATCGTGCAATTGGGCATTCGCTTGGATACAATCGCCACTCGCGCCGATTTGCA
AAGCGGCTTAATGGCCGCGCTCGAACGCCAAAACTTGACGATCGAGTCGATCTAA

Upstream 100 bases:

>100_bases
GCTGGAAGATATTACCACTCGCGCCGATTTACAAAGTGGCTTGCAGACCGCCCTTCGTCGCCAAGGCCAAATTATTCGTG
CTCGTTCGTGAGGTGCGCCC

Downstream 100 bases:

>100_bases
CGTGCTATAATCGCTGCATTAGGCATGGTCAAGTTGGTTACGCCCTAGCGTAGCCTTTGTGGATAGGAATTCTGGTTTTG
AGCTTCATTCTGTTGCTTGA

Product: anti-sigma-factor antagonist

Products: NA

Alternate protein names: Stressosome protein rsbRA [H]

Number of amino acids: Translated: 284; Mature: 283

Protein sequence:

>284_residues
MASSLNTLIRSSAWSVMSIGSAIYDQTGKVIYTNTALRRIFNLSPAEMLELQEHYNLFDDPSLATPELQADLKRAFAGEE
VFLPILDYVIVDAHGQPSNRHLAARFLLKPVGDATPPEYVVGYFHDVSESLELEAQISARRDEIDRMSQQDSLLKAEIAA
RAVPVVPILPGILVLPLVGGIDPMQADQIITALLQASSRSNADTVILDLTGVPVVDTAVANYILQAINALKLLGTETIVV
GISNEIAQTIVQLGIRLDTIATRADLQSGLMAALERQNLTIESI

Sequences:

>Translated_284_residues
MASSLNTLIRSSAWSVMSIGSAIYDQTGKVIYTNTALRRIFNLSPAEMLELQEHYNLFDDPSLATPELQADLKRAFAGEE
VFLPILDYVIVDAHGQPSNRHLAARFLLKPVGDATPPEYVVGYFHDVSESLELEAQISARRDEIDRMSQQDSLLKAEIAA
RAVPVVPILPGILVLPLVGGIDPMQADQIITALLQASSRSNADTVILDLTGVPVVDTAVANYILQAINALKLLGTETIVV
GISNEIAQTIVQLGIRLDTIATRADLQSGLMAALERQNLTIESI
>Mature_283_residues
ASSLNTLIRSSAWSVMSIGSAIYDQTGKVIYTNTALRRIFNLSPAEMLELQEHYNLFDDPSLATPELQADLKRAFAGEEV
FLPILDYVIVDAHGQPSNRHLAARFLLKPVGDATPPEYVVGYFHDVSESLELEAQISARRDEIDRMSQQDSLLKAEIAAR
AVPVVPILPGILVLPLVGGIDPMQADQIITALLQASSRSNADTVILDLTGVPVVDTAVANYILQAINALKLLGTETIVVG
ISNEIAQTIVQLGIRLDTIATRADLQSGLMAALERQNLTIESI

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014792
- InterPro:   IPR002645 [H]

Pfam domain/function: PF08678 Rsbr_N; PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 30783; Mature: 30652

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASSLNTLIRSSAWSVMSIGSAIYDQTGKVIYTNTALRRIFNLSPAEMLELQEHYNLFDD
CCCHHHHHHHHCCHHHHHHHHHHHHCCCCEEEECHHHHHHHCCCHHHHHHHHHHCCCCCC
PSLATPELQADLKRAFAGEEVFLPILDYVIVDAHGQPSNRHLAARFLLKPVGDATPPEYV
CCCCCCHHHHHHHHHHCCCHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHCCCCCCHHHH
VGYFHDVSESLELEAQISARRDEIDRMSQQDSLLKAEIAARAVPVVPILPGILVLPLVGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
IDPMQADQIITALLQASSRSNADTVILDLTGVPVVDTAVANYILQAINALKLLGTETIVV
CCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCEEEE
GISNEIAQTIVQLGIRLDTIATRADLQSGLMAALERQNLTIESI
ECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEECC
>Mature Secondary Structure 
ASSLNTLIRSSAWSVMSIGSAIYDQTGKVIYTNTALRRIFNLSPAEMLELQEHYNLFDD
CCHHHHHHHHCCHHHHHHHHHHHHCCCCEEEECHHHHHHHCCCHHHHHHHHHHCCCCCC
PSLATPELQADLKRAFAGEEVFLPILDYVIVDAHGQPSNRHLAARFLLKPVGDATPPEYV
CCCCCCHHHHHHHHHHCCCHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHCCCCCCHHHH
VGYFHDVSESLELEAQISARRDEIDRMSQQDSLLKAEIAARAVPVVPILPGILVLPLVGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
IDPMQADQIITALLQASSRSNADTVILDLTGVPVVDTAVANYILQAINALKLLGTETIVV
CCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCEEEE
GISNEIAQTIVQLGIRLDTIATRADLQSGLMAALERQNLTIESI
ECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 11157946; 10329124 [H]