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The map label for this gene is degS [H]

Identifier: 159897240

GI number: 159897240

Start: 817325

End: 818338

Strand: Reverse

Name: degS [H]

Synonym: Haur_0711

Alternate gene names: 159897240

Gene position: 818338-817325 (Counterclockwise)

Preceding gene: 159897241

Following gene: 159897239

Centisome position: 12.89

GC content: 54.73

Gene sequence:

>1014_bases
GTGGCCGATGCAGCAGCGTTACTTGCACAAGCACAGACCCAATTGGCAAATGCCTTGCAGGCCTTGCGAGGTGAGGCCGC
CCAACTGCGCGAGCGCCATACGGCAATTGCCCAACAAGGTCGTCAGATGTATCGAACTGCCGATGAGTTAGCGGTTCAGC
GCACCTTCGCCGAGCAACTTGGAACGCCAGCGGTCGGGCGGTTGCGCCAACAAGAGGCCGAGCTACGCAGCAAAATGGCC
AACCTCGATGCTGAAACCAGTGCCACCGCCGAAGCCCTCAAGCGGCTCGAACAATTAATTCGCCAGATCGAAATGAGCAG
CACCAGCCTCAGTGGCACAACCACAATAGGCCAACAAAATGACCCTTGGGCCTTGGCCTTACGTGGTCAAATTATCCAAG
GCCGTGAAGACGAACGCTTACGCCTGGCCCGTGAAGTACACGATGGGCCAGCCCAAGTTTTAGCGAACGTACTGATGGGC
CTCGAACATGCTATGAATTTGCATCAAAGCAATTCGCCGCAGATCGAGCCATTTTTGCACGAACTACGCAGCGCTGCCCG
CCAAGGCTTGCACGAAGTTCGTGGCTTTATCGCCGATTTACGGCCGGGCGCGCTCGACCAAGGCTTCCCTACTGCCCTCG
CTGACTATGTTCAAAAATACCAACAAACCACGAAGGTCAAAGTTACGATTGACCTGCTCCACTGGCCAAACCGCCTTCCG
GCTGAAGCTGAGATTGTGCTCTATCGGGTAACACAAGAAGCATTGCAAAATATCCATAAACATGCTCGCAATGCCAATGT
TTTGATCCGCAGTATGTTGCAAGGCAACCTGCTGATCGTCACCATCCGCGACGATGGCCCGGGCTTTGATCCACGAGAAG
TTGTGCGGCGCTCTGGCAAAGAGAGTTGGGGATTGACCAGTATGCGCGAACGAGTCGCCTTACTTGGCGGAGATTTTGCA
ATTGCTTCACGCCCCGGGGCTGGCACTGAAGTTACTATTCGGATTACGATCTAA

Upstream 100 bases:

>100_bases
AGATCACCCCTATTCCTATCGCCAATCGGCTGTTGCATCACCCGTACAGCGTGCTATACTTCAGATCTCAGAACTAGCAC
CATGTAGGAAGGAAGTCCTT

Downstream 100 bases:

>100_bases
GCTCATCCAGAAGGAGATACCCATGGAGCTAATTCGCGTTCTTATCATTGATGATCATCCACTTTTTCGCCAAGGCATCT
GCTGGAGCCTCGGCCAAGAA

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MADAAALLAQAQTQLANALQALRGEAAQLRERHTAIAQQGRQMYRTADELAVQRTFAEQLGTPAVGRLRQQEAELRSKMA
NLDAETSATAEALKRLEQLIRQIEMSSTSLSGTTTIGQQNDPWALALRGQIIQGREDERLRLAREVHDGPAQVLANVLMG
LEHAMNLHQSNSPQIEPFLHELRSAARQGLHEVRGFIADLRPGALDQGFPTALADYVQKYQQTTKVKVTIDLLHWPNRLP
AEAEIVLYRVTQEALQNIHKHARNANVLIRSMLQGNLLIVTIRDDGPGFDPREVVRRSGKESWGLTSMRERVALLGGDFA
IASRPGAGTEVTIRITI

Sequences:

>Translated_337_residues
MADAAALLAQAQTQLANALQALRGEAAQLRERHTAIAQQGRQMYRTADELAVQRTFAEQLGTPAVGRLRQQEAELRSKMA
NLDAETSATAEALKRLEQLIRQIEMSSTSLSGTTTIGQQNDPWALALRGQIIQGREDERLRLAREVHDGPAQVLANVLMG
LEHAMNLHQSNSPQIEPFLHELRSAARQGLHEVRGFIADLRPGALDQGFPTALADYVQKYQQTTKVKVTIDLLHWPNRLP
AEAEIVLYRVTQEALQNIHKHARNANVLIRSMLQGNLLIVTIRDDGPGFDPREVVRRSGKESWGLTSMRERVALLGGDFA
IASRPGAGTEVTIRITI
>Mature_336_residues
ADAAALLAQAQTQLANALQALRGEAAQLRERHTAIAQQGRQMYRTADELAVQRTFAEQLGTPAVGRLRQQEAELRSKMAN
LDAETSATAEALKRLEQLIRQIEMSSTSLSGTTTIGQQNDPWALALRGQIIQGREDERLRLAREVHDGPAQVLANVLMGL
EHAMNLHQSNSPQIEPFLHELRSAARQGLHEVRGFIADLRPGALDQGFPTALADYVQKYQQTTKVKVTIDLLHWPNRLPA
EAEIVLYRVTQEALQNIHKHARNANVLIRSMLQGNLLIVTIRDDGPGFDPREVVRRSGKESWGLTSMRERVALLGGDFAI
ASRPGAGTEVTIRITI

Specific function: Involved in a sensory transduction pathway that affect the production of enzymes that degrade polymeric carbon and nitrogen sources. DegS probably acts as a kinase that phosphorylates degU [H]

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787474, Length=198, Percent_Identity=26.2626262626263, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788812, Length=205, Percent_Identity=28.2926829268293, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI87082311, Length=89, Percent_Identity=40.4494382022472, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR008595
- InterPro:   IPR011712
- InterPro:   IPR005467
- InterPro:   IPR016381 [H]

Pfam domain/function: PF05384 DegS; PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 37282; Mature: 37151

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADAAALLAQAQTQLANALQALRGEAAQLRERHTAIAQQGRQMYRTADELAVQRTFAEQL
CCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GTPAVGRLRQQEAELRSKMANLDAETSATAEALKRLEQLIRQIEMSSTSLSGTTTIGQQN
CCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCC
DPWALALRGQIIQGREDERLRLAREVHDGPAQVLANVLMGLEHAMNLHQSNSPQIEPFLH
CCEEEEEECHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
ELRSAARQGLHEVRGFIADLRPGALDQGFPTALADYVQKYQQTTKVKVTIDLLHWPNRLP
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCEEEEEEEEEECCCCCC
AEAEIVLYRVTQEALQNIHKHARNANVLIRSMLQGNLLIVTIRDDGPGFDPREVVRRSGK
CCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHCCC
ESWGLTSMRERVALLGGDFAIASRPGAGTEVTIRITI
CCCCHHHHHHHHHHHCCCEEEECCCCCCCEEEEEEEC
>Mature Secondary Structure 
ADAAALLAQAQTQLANALQALRGEAAQLRERHTAIAQQGRQMYRTADELAVQRTFAEQL
CHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GTPAVGRLRQQEAELRSKMANLDAETSATAEALKRLEQLIRQIEMSSTSLSGTTTIGQQN
CCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCC
DPWALALRGQIIQGREDERLRLAREVHDGPAQVLANVLMGLEHAMNLHQSNSPQIEPFLH
CCEEEEEECHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
ELRSAARQGLHEVRGFIADLRPGALDQGFPTALADYVQKYQQTTKVKVTIDLLHWPNRLP
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCEEEEEEEEEECCCCCC
AEAEIVLYRVTQEALQNIHKHARNANVLIRSMLQGNLLIVTIRDDGPGFDPREVVRRSGK
CCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHCCC
ESWGLTSMRERVALLGGDFAIASRPGAGTEVTIRITI
CCCCHHHHHHHHHHHCCCEEEECCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7765823 [H]