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The map label for this gene is degU [H]

Identifier: 159897239

GI number: 159897239

Start: 816580

End: 817302

Strand: Reverse

Name: degU [H]

Synonym: Haur_0710

Alternate gene names: 159897239

Gene position: 817302-816580 (Counterclockwise)

Preceding gene: 159897240

Following gene: 159897238

Centisome position: 12.88

GC content: 50.76

Gene sequence:

>723_bases
ATGGAGCTAATTCGCGTTCTTATCATTGATGATCATCCACTTTTTCGCCAAGGCATCTGCTGGAGCCTCGGCCAAGAAAA
AGATATCGAGGTGATCGGCCAAGCTGAAAATGGCGCTGAGGCCATTAAGCTCACTGAAACCCTCAGCCCTAATGTTGTGT
TGCTAGATATTAATTTGCCAGGCTTGAATGGCTTGGAAGTTGCTCGCGTGCTCAAACGCCGAGCTCCACGCATGGGCATC
ATTGTGTTGAGTATTCACGACGATGATGAGCAATTGTTCAACGCCATCAAGGCTGGCGCTGCTGCTTACGCTTCCAAGGA
AATCGATCCCACGCAGCTGGTGGGCATGATTCGCGATGTTGCCCATGGCCGCTATGTGATCAACGAAAGCGTCATGTCAA
AGCCGCATGTGGCCACCCGCGTGCTCAACCAATTCCGCGAGCTTTCTAACGTGGCTAACAACAGCGAAGATACCTCGTCG
ATGTTTGCGCCATTGACCAGCCGCGAAATTGAAATTCTCGATTGTATTGCCCGTGGCCTTTCCAACAAAGAAATCGCCAA
TCAGCTGTCGATCAGCGGCCAAACCGTCAAAAACCACATCACCTCAATTCTTAGCAAGCTCCAAGTCAACGATCGCACGA
TGGCCGTTATTCACGCTATTCAACAAGGCTGGATCAAACTAGGCTATGATGAAAGTCGCGAAAGCCGCAGCCGCACCGCT
TGA

Upstream 100 bases:

>100_bases
GCCTTACTTGGCGGAGATTTTGCAATTGCTTCACGCCCCGGGGCTGGCACTGAAGTTACTATTCGGATTACGATCTAAGC
TCATCCAGAAGGAGATACCC

Downstream 100 bases:

>100_bases
CGAACCAGCCTGCTCTCGGTTAAAGTTGGCCTATCGCTGTTAATTCGCAGCCTCGCAGTAGCGAGGCTGTTCTTTTTGGA
GCAGAGTAATGTCGATCGCA

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MELIRVLIIDDHPLFRQGICWSLGQEKDIEVIGQAENGAEAIKLTETLSPNVVLLDINLPGLNGLEVARVLKRRAPRMGI
IVLSIHDDDEQLFNAIKAGAAAYASKEIDPTQLVGMIRDVAHGRYVINESVMSKPHVATRVLNQFRELSNVANNSEDTSS
MFAPLTSREIEILDCIARGLSNKEIANQLSISGQTVKNHITSILSKLQVNDRTMAVIHAIQQGWIKLGYDESRESRSRTA

Sequences:

>Translated_240_residues
MELIRVLIIDDHPLFRQGICWSLGQEKDIEVIGQAENGAEAIKLTETLSPNVVLLDINLPGLNGLEVARVLKRRAPRMGI
IVLSIHDDDEQLFNAIKAGAAAYASKEIDPTQLVGMIRDVAHGRYVINESVMSKPHVATRVLNQFRELSNVANNSEDTSS
MFAPLTSREIEILDCIARGLSNKEIANQLSISGQTVKNHITSILSKLQVNDRTMAVIHAIQQGWIKLGYDESRESRSRTA
>Mature_240_residues
MELIRVLIIDDHPLFRQGICWSLGQEKDIEVIGQAENGAEAIKLTETLSPNVVLLDINLPGLNGLEVARVLKRRAPRMGI
IVLSIHDDDEQLFNAIKAGAAAYASKEIDPTQLVGMIRDVAHGRYVINESVMSKPHVATRVLNQFRELSNVANNSEDTSS
MFAPLTSREIEILDCIARGLSNKEIANQLSISGQTVKNHITSILSKLQVNDRTMAVIHAIQQGWIKLGYDESRESRSRTA

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=219, Percent_Identity=39.2694063926941, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1788222, Length=222, Percent_Identity=34.6846846846847, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1787473, Length=217, Percent_Identity=35.0230414746544, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1790102, Length=223, Percent_Identity=30.9417040358744, Blast_Score=97, Evalue=7e-22,
Organism=Escherichia coli, GI1788712, Length=206, Percent_Identity=28.1553398058252, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1786747, Length=207, Percent_Identity=28.0193236714976, Blast_Score=80, Evalue=9e-17,
Organism=Escherichia coli, GI87082052, Length=111, Percent_Identity=34.2342342342342, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788546, Length=214, Percent_Identity=27.1028037383178, Blast_Score=64, Evalue=6e-12,
Organism=Escherichia coli, GI1790299, Length=88, Percent_Identity=32.9545454545455, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 26560; Mature: 26560

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELIRVLIIDDHPLFRQGICWSLGQEKDIEVIGQAENGAEAIKLTETLSPNVVLLDINLP
CCEEEEEEECCCCHHHHCCHHCCCCCCCCEEEECCCCCCCEEEEEECCCCCEEEEEECCC
GLNGLEVARVLKRRAPRMGIIVLSIHDDDEQLFNAIKAGAAAYASKEIDPTQLVGMIRDV
CCCHHHHHHHHHHCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
AHGRYVINESVMSKPHVATRVLNQFRELSNVANNSEDTSSMFAPLTSREIEILDCIARGL
HCCCEEECHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCHHHHHHHHHHCC
SNKEIANQLSISGQTVKNHITSILSKLQVNDRTMAVIHAIQQGWIKLGYDESRESRSRTA
CCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEECCCCCCHHHCCCCC
>Mature Secondary Structure
MELIRVLIIDDHPLFRQGICWSLGQEKDIEVIGQAENGAEAIKLTETLSPNVVLLDINLP
CCEEEEEEECCCCHHHHCCHHCCCCCCCCEEEECCCCCCCEEEEEECCCCCEEEEEECCC
GLNGLEVARVLKRRAPRMGIIVLSIHDDDEQLFNAIKAGAAAYASKEIDPTQLVGMIRDV
CCCHHHHHHHHHHCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
AHGRYVINESVMSKPHVATRVLNQFRELSNVANNSEDTSSMFAPLTSREIEILDCIARGL
HCCCEEECHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCHHHHHHHHHHCC
SNKEIANQLSISGQTVKNHITSILSKLQVNDRTMAVIHAIQQGWIKLGYDESRESRSRTA
CCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEECCCCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7765823 [H]