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The map label for this gene is aroB [H]

Identifier: 159896799

GI number: 159896799

Start: 313141

End: 314760

Strand: Reverse

Name: aroB [H]

Synonym: Haur_0266

Alternate gene names: 159896799

Gene position: 314760-313141 (Counterclockwise)

Preceding gene: 159896801

Following gene: 159896797

Centisome position: 4.96

GC content: 53.15

Gene sequence:

>1620_bases
ATGCAACCATCTGGGCAATCGATTGCATTAATTGGCCCAAGCGGCGCAGGCAAAAGTACGGTTGGCGTAGGTTTAGCCCA
AGCGCTCGGCTGGCGTTTTATCGATTTAGATCAACTGATTATCGAACGCGCTGAAAAAAGTATTAGCGACATTTTTAGCC
AAGAGGGCGAAGCAGGCTTTCGTGAGCGCGAAACCGCCGCTTTGGTCCAAGCACTACAAACAGATCAAGCCGTCATCGCC
TGTGGTGGCGGCATCGTTTTGCGCGAAATTAATCGGCAATTGCTGCGTGAACAGGCTTGGTGTGTCTATCTCACCAGCGC
CATCAGCACCTTGGTTAAACGTTTAACTGCCGATCAAGCCAATCCTCGGCCATTGCTGGCGAGCGATATTAATGAACAAC
TGGTGATTCAGCTCGCCGAGCGTTTGCCACTTTACAGCACCCTTGCCAACTGGACGATCCAGACCGATGGCTTGGCTCCA
CAAATTGTGGTCGAACAACTCATTCGGGCTTGGGGTTTAGTGGGCAAACCGCAGGTCAGCGAAGTGTTTAGCTCATTCAA
CAGTCGTTATTATGTCAAAAGCGGCGCACTGGCAGCCCTACCCAATGAATTAGCCAATCTTGGCCTCACTGGCACATGCT
GGCTAATCAGCGACAGTCATGTTGGGCCGATGTATGCGCCAACCTTGATTCAAGCCTTAGAAAACTCCGGTTTCAGCTGC
CAACGCTACGATATTCCGGCGCAAGAGGCTAGCAAATCATGGCAGCAAGCAGGCGAATTATATACATGGCTGCTCGAAAA
TGGCGTGCAGCGTGGCGATACGGTGTTGGCGTTGGGCGGCGGCGTGGTTGGCGATTTAGCGGGCTTTATCGCGGCCTCAA
TTTTGCGCGGCATCGCGGTCGTGCAATTGCCAACCACAATTTTGGCGATGATCGATAGCAGCATTGGTGGCAAAACAGGC
ATTAATCATCCACGGGGCAAAAATTTGATCGGTGCGTTTCATCCGCCACGTTTGGTGTTAATTGATGATGCAGTATTGAG
CAGTTTGCCGCGTCGCGAGCGGGCAGCAGGCTGGGCCGAAGCCGTCAAACATGGCGTGATTGCTGATGCGCAGTTGTTCG
CTGATTTGGAGCAAGCAGGGGCAAGCCTCAATGATGTGCCCGCCAAAATAACCAGCGATCTGTTGGTACGCTCGGCGGCG
GTCAAAATTGGCGTGGTCAATCGCGACGAACGCGAAACTGGCGAACGCATGTTGCTCAATTATGGCCATACCTTGGGCCA
AGCCGTCGAGGCCGCGACCCAATACAAACGCTATGTGCATGGCGAAGCAGTAGCGATTGGCATGACCTTTGCTGCCAATC
TGGCAGTGCAACTTGGCATGTGGTCTAGCGCCGAGGCCGAGCGTCAACGGGCTTTGTTGCAAGCACTCGAATTACCAACC
GCCCTGCCGCGTGATTTGGATATCGAGGCGACTTTGGCAGCTTTGAACTTAGATAAGAAACGTGCCAAAGGCAGCGTGCG
TTGGGTATTGCCAACCCGCATCGGCCATGCGCAAGTTGAATCACACGTTGACCCAGAATTGGTGCGCAAATTGGTGCACG
AATTGGTCGAGCAAACCTAA

Upstream 100 bases:

>100_bases
CTTTTGATCCAACAATTTGCCTGAGCATCGCCAAAGGTGCTACCATTCGCCACAGATGGGATGCCAAGTTTGGCATTATT
GGTAATGGAAGGACACAAAC

Downstream 100 bases:

>100_bases
ATTTGAGTCCCCCGACCATCGAGCATTACAAGGGTAGGTTTTTAACAAAGGTACGGTGGAATCGCCGTCGATGTTCATGC
CCTCACCCCCTAGTCCCCTC

Product: shikimate kinase., 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 539; Mature: 539

Protein sequence:

>539_residues
MQPSGQSIALIGPSGAGKSTVGVGLAQALGWRFIDLDQLIIERAEKSISDIFSQEGEAGFRERETAALVQALQTDQAVIA
CGGGIVLREINRQLLREQAWCVYLTSAISTLVKRLTADQANPRPLLASDINEQLVIQLAERLPLYSTLANWTIQTDGLAP
QIVVEQLIRAWGLVGKPQVSEVFSSFNSRYYVKSGALAALPNELANLGLTGTCWLISDSHVGPMYAPTLIQALENSGFSC
QRYDIPAQEASKSWQQAGELYTWLLENGVQRGDTVLALGGGVVGDLAGFIAASILRGIAVVQLPTTILAMIDSSIGGKTG
INHPRGKNLIGAFHPPRLVLIDDAVLSSLPRRERAAGWAEAVKHGVIADAQLFADLEQAGASLNDVPAKITSDLLVRSAA
VKIGVVNRDERETGERMLLNYGHTLGQAVEAATQYKRYVHGEAVAIGMTFAANLAVQLGMWSSAEAERQRALLQALELPT
ALPRDLDIEATLAALNLDKKRAKGSVRWVLPTRIGHAQVESHVDPELVRKLVHELVEQT

Sequences:

>Translated_539_residues
MQPSGQSIALIGPSGAGKSTVGVGLAQALGWRFIDLDQLIIERAEKSISDIFSQEGEAGFRERETAALVQALQTDQAVIA
CGGGIVLREINRQLLREQAWCVYLTSAISTLVKRLTADQANPRPLLASDINEQLVIQLAERLPLYSTLANWTIQTDGLAP
QIVVEQLIRAWGLVGKPQVSEVFSSFNSRYYVKSGALAALPNELANLGLTGTCWLISDSHVGPMYAPTLIQALENSGFSC
QRYDIPAQEASKSWQQAGELYTWLLENGVQRGDTVLALGGGVVGDLAGFIAASILRGIAVVQLPTTILAMIDSSIGGKTG
INHPRGKNLIGAFHPPRLVLIDDAVLSSLPRRERAAGWAEAVKHGVIADAQLFADLEQAGASLNDVPAKITSDLLVRSAA
VKIGVVNRDERETGERMLLNYGHTLGQAVEAATQYKRYVHGEAVAIGMTFAANLAVQLGMWSSAEAERQRALLQALELPT
ALPRDLDIEATLAALNLDKKRAKGSVRWVLPTRIGHAQVESHVDPELVRKLVHELVEQT
>Mature_539_residues
MQPSGQSIALIGPSGAGKSTVGVGLAQALGWRFIDLDQLIIERAEKSISDIFSQEGEAGFRERETAALVQALQTDQAVIA
CGGGIVLREINRQLLREQAWCVYLTSAISTLVKRLTADQANPRPLLASDINEQLVIQLAERLPLYSTLANWTIQTDGLAP
QIVVEQLIRAWGLVGKPQVSEVFSSFNSRYYVKSGALAALPNELANLGLTGTCWLISDSHVGPMYAPTLIQALENSGFSC
QRYDIPAQEASKSWQQAGELYTWLLENGVQRGDTVLALGGGVVGDLAGFIAASILRGIAVVQLPTTILAMIDSSIGGKTG
INHPRGKNLIGAFHPPRLVLIDDAVLSSLPRRERAAGWAEAVKHGVIADAQLFADLEQAGASLNDVPAKITSDLLVRSAA
VKIGVVNRDERETGERMLLNYGHTLGQAVEAATQYKRYVHGEAVAIGMTFAANLAVQLGMWSSAEAERQRALLQALELPT
ALPRDLDIEATLAALNLDKKRAKGSVRWVLPTRIGHAQVESHVDPELVRKLVHELVEQT

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=314, Percent_Identity=43.312101910828, Blast_Score=230, Evalue=2e-61,
Organism=Escherichia coli, GI1786587, Length=162, Percent_Identity=40.1234567901235, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI87082255, Length=165, Percent_Identity=38.7878787878788, Blast_Score=100, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6320332, Length=316, Percent_Identity=35.7594936708861, Blast_Score=180, Evalue=5e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 58051; Mature: 58051

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPSGQSIALIGPSGAGKSTVGVGLAQALGWRFIDLDQLIIERAEKSISDIFSQEGEAGF
CCCCCCEEEEECCCCCCCCHHHHHHHHHHCCEEECHHHHHHHHHHHHHHHHHHCCCCCCC
RERETAALVQALQTDQAVIACGGGIVLREINRQLLREQAWCVYLTSAISTLVKRLTADQA
HHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NPRPLLASDINEQLVIQLAERLPLYSTLANWTIQTDGLAPQIVVEQLIRAWGLVGKPQVS
CCCCCHHHCCHHHHHHHHHHHCCHHHHHHCCEEECCCCCHHHHHHHHHHHHCCCCCCHHH
EVFSSFNSRYYVKSGALAALPNELANLGLTGTCWLISDSHVGPMYAPTLIQALENSGFSC
HHHHHHCCEEEEECCCHHHCCHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCE
QRYDIPAQEASKSWQQAGELYTWLLENGVQRGDTVLALGGGVVGDLAGFIAASILRGIAV
EECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHH
VQLPTTILAMIDSSIGGKTGINHPRGKNLIGAFHPPRLVLIDDAVLSSLPRRERAAGWAE
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCEECCCCCEEEEECHHHHHHCCCHHHHCCHHH
AVKHGVIADAQLFADLEQAGASLNDVPAKITSDLLVRSAAVKIGVVNRDERETGERMLLN
HHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHH
YGHTLGQAVEAATQYKRYVHGEAVAIGMTFAANLAVQLGMWSSAEAERQRALLQALELPT
HCHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCC
ALPRDLDIEATLAALNLDKKRAKGSVRWVLPTRIGHAQVESHVDPELVRKLVHELVEQT
CCCCCCCCHHHHHHHCCCHHHCCCCEEEEECCCCCHHHHHHCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQPSGQSIALIGPSGAGKSTVGVGLAQALGWRFIDLDQLIIERAEKSISDIFSQEGEAGF
CCCCCCEEEEECCCCCCCCHHHHHHHHHHCCEEECHHHHHHHHHHHHHHHHHHCCCCCCC
RERETAALVQALQTDQAVIACGGGIVLREINRQLLREQAWCVYLTSAISTLVKRLTADQA
HHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NPRPLLASDINEQLVIQLAERLPLYSTLANWTIQTDGLAPQIVVEQLIRAWGLVGKPQVS
CCCCCHHHCCHHHHHHHHHHHCCHHHHHHCCEEECCCCCHHHHHHHHHHHHCCCCCCHHH
EVFSSFNSRYYVKSGALAALPNELANLGLTGTCWLISDSHVGPMYAPTLIQALENSGFSC
HHHHHHCCEEEEECCCHHHCCHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCE
QRYDIPAQEASKSWQQAGELYTWLLENGVQRGDTVLALGGGVVGDLAGFIAASILRGIAV
EECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHH
VQLPTTILAMIDSSIGGKTGINHPRGKNLIGAFHPPRLVLIDDAVLSSLPRRERAAGWAE
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCEECCCCCEEEEECHHHHHHCCCHHHHCCHHH
AVKHGVIADAQLFADLEQAGASLNDVPAKITSDLLVRSAAVKIGVVNRDERETGERMLLN
HHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHH
YGHTLGQAVEAATQYKRYVHGEAVAIGMTFAANLAVQLGMWSSAEAERQRALLQALELPT
HCHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCC
ALPRDLDIEATLAALNLDKKRAKGSVRWVLPTRIGHAQVESHVDPELVRKLVHELVEQT
CCCCCCCCHHHHHHHCCCHHHCCCCEEEEECCCCCHHHHHHCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA