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The map label for this gene is fchA [H]

Identifier: 159896796

GI number: 159896796

Start: 308571

End: 310058

Strand: Direct

Name: fchA [H]

Synonym: Haur_0263

Alternate gene names: 159896796

Gene position: 308571-310058 (Clockwise)

Preceding gene: 159896794

Following gene: 159896798

Centisome position: 4.86

GC content: 54.23

Gene sequence:

>1488_bases
ATGGGCTTGGTCGAAAGTATTATGAATTTCAGCGAAGGTCGGCGCACCGAAGTTGTGCACGCCATTCGTGATGCAATTAC
GGCTGTTGCCGGCGTGCAATTGCTCGATGTTCAATCCGACGCTGATCATAATCGCACGGTGATTAGTTTTGCGGGCGAGG
CTGAAGCAGTTGGCGAAGCTGCTTTCCAAGCAACCCGCACCGCCCAAGGCTTAATTAATTTGGATACCCATCGCGGCGAA
CACCCACGCATCGGCGCGACCGATGTCTTGCCATTTGTGCCACTTGGCCAAACCACGATGAAACAGTGTGTGGCCTTGGC
TCGCAAAGTTGGCAAGCGCATTGGTGATGAATTGGGGATTGCGGTTTATTTGTATGAAGAGGCTGCGACCCGCCCCGAAC
GTCAAAATTTGGCCGATGTGCGTAAGGGCGAATATGAGGCTTGGCGCAAAGCCATTGGGGTTGATCCGGCGCGGGAGCCA
GATTTTGGCCCAGCCGTGGCGACACCTGCAGGCGCAACCGTGGTTGGGGCACGCCAGCCATTGATTGCCTACAACATCTA
TTTAAATACCACCGATGTAGAAATTGCCAAAAAAATCGCTAAATCGATTCGCTATCTTGGCGGTGGCTTGCGCTATGTCA
AAGCTTTGGGCTTGTTGGTCGATGGTCGCGCTCAAATCTCGATGAACTTGGTTAATTTCCGTGGAACGCCAATTCATCGA
GTGCAGGAGTTAGTACGCGCCGAGGCCATGCGCTATGGCGTGACGATTACTGAGGGCGAAGTTATTGGGCTTGTGCCGCA
AGATGCGCTGGTTGATGCTGCTGAGCATTATCTGCAACTCAATCGTTTTCGCCGCGACCAAGTGCTTGAATCGAAGTTGG
CCGCGCCAAGTGCTGGCGATGACTGGTTGCCAACCAACACGTTCCAAGCCTTTGCAGCTGGGACACCAACGCCTGGTGGT
GGTTCGGCGGCGGCCTTAGCTGGGGCTTTGGCTGGCTCGTTGGGCCAAATGGTGGCTAATTTAACCGTCAGCCGCAAAAA
ATATGCAGCGGTCAAGCCCAGCATGCAAGCGGCCTTGGAGCGCTTGAGCGAAGCAACCACCAGCTTGGGCAAATTGGCTT
TGTCCGATAGTGCCGCATTTAACGCCATCAGCGTCACGCGTAAATTGCCTGAAGAGCAGGCTGACCGAGCGCAACAATTG
GCGGCGGCGATTGTGCATGCCTGTGAAGTTCCCTTGCAAGTGGCCCAACAAGCTGCCAGTTTGTTTGATGATTTATATCT
GTTGGCGACCCAAGGCAACGTCAATGCCCGCACCGATGCCCAAGTCGGCGGCTATTTGGCCTATGCCGCCGTCAATGGGG
CTGGCTTAAATGTGTTGGTCAATCTTGGCGATTTAAGCGATGCTCAATTGCGTGAACAATTCAGCGCGGCGGTTGCCAAG
CTGCGCCAACAAGCTGAGCAAGGCTTGCAAAAACTGACGACACTCTAG

Upstream 100 bases:

>100_bases
GATGTCAATAAGCGATTAACGTTAATCGCCATTTGTTTAACCAAATTCTCACCATCTGAGCTATACTTGGGCGGTTGTGG
TTCGTCAAAGGAGACATTCA

Downstream 100 bases:

>100_bases
GCAGGGTTATGCTACAATGAGCACATAGATCAACTTCTGCGTATCGCGAGGAGATTTTTCAATGGCTCGTTGGCTTCTGA
TTGTCGTTGGCTTAGCTGCT

Product: glutamate formiminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 495; Mature: 494

Protein sequence:

>495_residues
MGLVESIMNFSEGRRTEVVHAIRDAITAVAGVQLLDVQSDADHNRTVISFAGEAEAVGEAAFQATRTAQGLINLDTHRGE
HPRIGATDVLPFVPLGQTTMKQCVALARKVGKRIGDELGIAVYLYEEAATRPERQNLADVRKGEYEAWRKAIGVDPAREP
DFGPAVATPAGATVVGARQPLIAYNIYLNTTDVEIAKKIAKSIRYLGGGLRYVKALGLLVDGRAQISMNLVNFRGTPIHR
VQELVRAEAMRYGVTITEGEVIGLVPQDALVDAAEHYLQLNRFRRDQVLESKLAAPSAGDDWLPTNTFQAFAAGTPTPGG
GSAAALAGALAGSLGQMVANLTVSRKKYAAVKPSMQAALERLSEATTSLGKLALSDSAAFNAISVTRKLPEEQADRAQQL
AAAIVHACEVPLQVAQQAASLFDDLYLLATQGNVNARTDAQVGGYLAYAAVNGAGLNVLVNLGDLSDAQLREQFSAAVAK
LRQQAEQGLQKLTTL

Sequences:

>Translated_495_residues
MGLVESIMNFSEGRRTEVVHAIRDAITAVAGVQLLDVQSDADHNRTVISFAGEAEAVGEAAFQATRTAQGLINLDTHRGE
HPRIGATDVLPFVPLGQTTMKQCVALARKVGKRIGDELGIAVYLYEEAATRPERQNLADVRKGEYEAWRKAIGVDPAREP
DFGPAVATPAGATVVGARQPLIAYNIYLNTTDVEIAKKIAKSIRYLGGGLRYVKALGLLVDGRAQISMNLVNFRGTPIHR
VQELVRAEAMRYGVTITEGEVIGLVPQDALVDAAEHYLQLNRFRRDQVLESKLAAPSAGDDWLPTNTFQAFAAGTPTPGG
GSAAALAGALAGSLGQMVANLTVSRKKYAAVKPSMQAALERLSEATTSLGKLALSDSAAFNAISVTRKLPEEQADRAQQL
AAAIVHACEVPLQVAQQAASLFDDLYLLATQGNVNARTDAQVGGYLAYAAVNGAGLNVLVNLGDLSDAQLREQFSAAVAK
LRQQAEQGLQKLTTL
>Mature_494_residues
GLVESIMNFSEGRRTEVVHAIRDAITAVAGVQLLDVQSDADHNRTVISFAGEAEAVGEAAFQATRTAQGLINLDTHRGEH
PRIGATDVLPFVPLGQTTMKQCVALARKVGKRIGDELGIAVYLYEEAATRPERQNLADVRKGEYEAWRKAIGVDPAREPD
FGPAVATPAGATVVGARQPLIAYNIYLNTTDVEIAKKIAKSIRYLGGGLRYVKALGLLVDGRAQISMNLVNFRGTPIHRV
QELVRAEAMRYGVTITEGEVIGLVPQDALVDAAEHYLQLNRFRRDQVLESKLAAPSAGDDWLPTNTFQAFAAGTPTPGGG
SAAALAGALAGSLGQMVANLTVSRKKYAAVKPSMQAALERLSEATTSLGKLALSDSAAFNAISVTRKLPEEQADRAQQLA
AAIVHACEVPLQVAQQAASLFDDLYLLATQGNVNARTDAQVGGYLAYAAVNGAGLNVLVNLGDLSDAQLREQFSAAVAKL
RQQAEQGLQKLTTL

Specific function: Required for both C1 and C2 metabolism [H]

COG id: COG3643

COG function: function code E; Glutamate formiminotransferase

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cyclodeaminase/cyclohydrolase family [H]

Homologues:

Organism=Homo sapiens, GI46255035, Length=526, Percent_Identity=35.5513307984791, Blast_Score=271, Evalue=1e-72,
Organism=Homo sapiens, GI11140815, Length=526, Percent_Identity=35.5513307984791, Blast_Score=271, Evalue=1e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007044 [H]

Pfam domain/function: PF04961 FTCD_C [H]

EC number: =3.5.4.9 [H]

Molecular weight: Translated: 52629; Mature: 52498

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLVESIMNFSEGRRTEVVHAIRDAITAVAGVQLLDVQSDADHNRTVISFAGEAEAVGEA
CCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCEEEEECCCHHHHHHH
AFQATRTAQGLINLDTHRGEHPRIGATDVLPFVPLGQTTMKQCVALARKVGKRIGDELGI
HHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHCCE
AVYLYEEAATRPERQNLADVRKGEYEAWRKAIGVDPAREPDFGPAVATPAGATVVGARQP
EEEEEECCCCCCCHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCC
LIAYNIYLNTTDVEIAKKIAKSIRYLGGGLRYVKALGLLVDGRAQISMNLVNFRGTPIHR
EEEEEEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHH
VQELVRAEAMRYGVTITEGEVIGLVPQDALVDAAEHYLQLNRFRRDQVLESKLAAPSAGD
HHHHHHHHHHHHCCEEECCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DWLPTNTFQAFAAGTPTPGGGSAAALAGALAGSLGQMVANLTVSRKKYAAVKPSMQAALE
CCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
RLSEATTSLGKLALSDSAAFNAISVTRKLPEEQADRAQQLAAAIVHACEVPLQVAQQAAS
HHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
LFDDLYLLATQGNVNARTDAQVGGYLAYAAVNGAGLNVLVNLGDLSDAQLREQFSAAVAK
HHHHHEEEEECCCCCCCCCCCCCCEEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHH
LRQQAEQGLQKLTTL
HHHHHHHHHHHHHCC
>Mature Secondary Structure 
GLVESIMNFSEGRRTEVVHAIRDAITAVAGVQLLDVQSDADHNRTVISFAGEAEAVGEA
CHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCEEEEECCCHHHHHHH
AFQATRTAQGLINLDTHRGEHPRIGATDVLPFVPLGQTTMKQCVALARKVGKRIGDELGI
HHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHCCE
AVYLYEEAATRPERQNLADVRKGEYEAWRKAIGVDPAREPDFGPAVATPAGATVVGARQP
EEEEEECCCCCCCHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCC
LIAYNIYLNTTDVEIAKKIAKSIRYLGGGLRYVKALGLLVDGRAQISMNLVNFRGTPIHR
EEEEEEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHH
VQELVRAEAMRYGVTITEGEVIGLVPQDALVDAAEHYLQLNRFRRDQVLESKLAAPSAGD
HHHHHHHHHHHHCCEEECCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DWLPTNTFQAFAAGTPTPGGGSAAALAGALAGSLGQMVANLTVSRKKYAAVKPSMQAALE
CCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
RLSEATTSLGKLALSDSAAFNAISVTRKLPEEQADRAQQLAAAIVHACEVPLQVAQQAAS
HHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
LFDDLYLLATQGNVNARTDAQVGGYLAYAAVNGAGLNVLVNLGDLSDAQLREQFSAAVAK
HHHHHEEEEECCCCCCCCCCCCCCEEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHH
LRQQAEQGLQKLTTL
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7961516; 10215859 [H]