Click here to switch to the map view.

The map label for this gene is rfbC [H]

Identifier: 159896798

GI number: 159896798

Start: 312379

End: 312945

Strand: Direct

Name: rfbC [H]

Synonym: Haur_0265

Alternate gene names: 159896798

Gene position: 312379-312945 (Clockwise)

Preceding gene: 159896796

Following gene: 159896800

Centisome position: 4.92

GC content: 50.62

Gene sequence:

>567_bases
ATGAGTTTGACCGTAACGCAAACCGCGCTTGATGGCGTTGTCATTATTAAACCAAGCGTGTTTGCCGATGAACGCGGCTT
CTTCCTTGAAACATACCATCAGATCAAGTTTGCTGACCTCGGTCTGCCTACCGATTTTGTGCAAGATAATCACTCCCGTT
CCAAGCAAGGGGTACTGCGCGGGCTGCATTATCAAGATGAGCGCCAGCCAATGGCAAAACTTGTGCGTTGTAGTGTTGGT
AGCATTTTTGATGTTGCTGTTGATTTGCGCGTTGGCTCGCCGACCTTTGGCAAATGGGTTGGAGTTGAGCTAAGCGCCGA
TAACTTTTTACAATTTCTGATTCCTTCGGGCTTTGGCCATGGCTTTGTGGTGCTTTCGGAGTTTGCCGAGGTGCAATATC
GTTGTACAGGGTTGTATGCGCCCGAAACCGAGGGTGCGGTGCGCTGGAATGACCCACAAATTGGGATTGAGTGGCCAATC
AGTGAGCCAACGCTCTCAGGTCGTGATCAAGCGGCAATGAGCCTCGCCGACTATCTTGAGAATCCTGCGTTTCGTTATCG
TGGCTAG

Upstream 100 bases:

>100_bases
AACTGAATATGACTAATCTTCATACAAAACTCACGTTGGGCAGCTATGCTCTATAATTGTGGGATAATTGAACCCACCAA
TGGCGAAAGGACGAAAGGCA

Downstream 100 bases:

>100_bases
ACGTTCCCTCACCCTCAACCCCTCTCCCACGGCGGCGGGAGAGGGGAGTTCCAGTCGTCAATGATGGCGGGTTCCCCCTC
GCCTCGCGTGCGGGAGAGGG

Product: dTDP-4-dehydrorhamnose 3,5-epimerase

Products: NA

Alternate protein names: Thymidine diphospho-4-keto-rhamnose 3,5-epimerase; dTDP-4-keto-6-deoxyglucose 3,5-epimerase; dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; dTDP-L-rhamnose synthase [H]

Number of amino acids: Translated: 188; Mature: 187

Protein sequence:

>188_residues
MSLTVTQTALDGVVIIKPSVFADERGFFLETYHQIKFADLGLPTDFVQDNHSRSKQGVLRGLHYQDERQPMAKLVRCSVG
SIFDVAVDLRVGSPTFGKWVGVELSADNFLQFLIPSGFGHGFVVLSEFAEVQYRCTGLYAPETEGAVRWNDPQIGIEWPI
SEPTLSGRDQAAMSLADYLENPAFRYRG

Sequences:

>Translated_188_residues
MSLTVTQTALDGVVIIKPSVFADERGFFLETYHQIKFADLGLPTDFVQDNHSRSKQGVLRGLHYQDERQPMAKLVRCSVG
SIFDVAVDLRVGSPTFGKWVGVELSADNFLQFLIPSGFGHGFVVLSEFAEVQYRCTGLYAPETEGAVRWNDPQIGIEWPI
SEPTLSGRDQAAMSLADYLENPAFRYRG
>Mature_187_residues
SLTVTQTALDGVVIIKPSVFADERGFFLETYHQIKFADLGLPTDFVQDNHSRSKQGVLRGLHYQDERQPMAKLVRCSVGS
IFDVAVDLRVGSPTFGKWVGVELSADNFLQFLIPSGFGHGFVVLSEFAEVQYRCTGLYAPETEGAVRWNDPQIGIEWPIS
EPTLSGRDQAAMSLADYLENPAFRYRG

Specific function: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose [H]

COG id: COG1898

COG function: function code M; dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1788350, Length=179, Percent_Identity=50.8379888268156, Blast_Score=186, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI17550412, Length=172, Percent_Identity=49.4186046511628, Blast_Score=152, Evalue=9e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR000888
- InterPro:   IPR014710
- ProDom:   PD001462 [H]

Pfam domain/function: PF00908 dTDP_sugar_isom [H]

EC number: =5.1.3.13 [H]

Molecular weight: Translated: 20937; Mature: 20806

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLTVTQTALDGVVIIKPSVFADERGFFLETYHQIKFADLGLPTDFVQDNHSRSKQGVLR
CCEEEEEHHHCEEEEECCCEECCCCCCEEEHHHEEEEECCCCCHHHHCCCCCCCHHHHHH
GLHYQDERQPMAKLVRCSVGSIFDVAVDLRVGSPTFGKWVGVELSADNFLQFLIPSGFGH
CCCCCCHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCEEEEEECHHHEEEEECCCCCCC
GFVVLSEFAEVQYRCTGLYAPETEGAVRWNDPQIGIEWPISEPTLSGRDQAAMSLADYLE
HHHHHHHHHHHEEEEEEEECCCCCCCEEECCCCCEEECCCCCCCCCCCHHHHHHHHHHHC
NPAFRYRG
CCCEECCC
>Mature Secondary Structure 
SLTVTQTALDGVVIIKPSVFADERGFFLETYHQIKFADLGLPTDFVQDNHSRSKQGVLR
CEEEEEHHHCEEEEECCCEECCCCCCEEEHHHEEEEECCCCCHHHHCCCCCCCHHHHHH
GLHYQDERQPMAKLVRCSVGSIFDVAVDLRVGSPTFGKWVGVELSADNFLQFLIPSGFGH
CCCCCCHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCEEEEEECHHHEEEEECCCCCCC
GFVVLSEFAEVQYRCTGLYAPETEGAVRWNDPQIGIEWPISEPTLSGRDQAAMSLADYLE
HHHHHHHHHHHEEEEEEEECCCCCCCEEECCCCCEEECCCCCCCCCCCHHHHHHHHHHHC
NPAFRYRG
CCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1710759; 11677609; 10802738 [H]