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The map label for this gene is napA [H]

Identifier: 159041975

GI number: 159041975

Start: 1490109

End: 1491296

Strand: Reverse

Name: napA [H]

Synonym: Cmaq_1412

Alternate gene names: 159041975

Gene position: 1491296-1490109 (Counterclockwise)

Preceding gene: 159041979

Following gene: 159041971

Centisome position: 71.78

GC content: 44.53

Gene sequence:

>1188_bases
ATGGCGGTTGGTTCAATATACTTAACGCTACTGGAGTTCGCAATACTAGTAACCACTGCAGAATCCCTCAGCCTAATCCT
AGCCAAGTACAAGTACCCGAGTATTGTGGCAGAGTTACTGACTGGTATAGCATTAAGCCCATATGCCCTAGGCGGGTTAC
TTAACGCCTTACTCCACGTTGACTTATTCTCAATAAACAACTACGTGGTGTTTCTATCCGAGTTCTCAGTAATACTCCTC
CTATTCGCCTCAGGGCTTGGGCATGGATTATCCTCACTTAAACAGGGTGGATTCCCTGGGTTAATGGCTGCTGTAGCCGG
TGCCATATTACCCTTCATGACTGTTTACTGGTACTGCACTAGTGTTGGTTTTAGTCAAGTGGCTGCATCACTCATAGCCC
TATCAACAGCACCCACTAGCCTAGCCGTTGTTGCTAACATTATTGAGAGGGAGGGGCTTCATGAACTCCCAAGCACCAAG
GTGCTTGTGGCCGCTGCCTCAGTGGATGACGTGGTTGCACTCATACTGCTCTCCACATTACCCACAAGTCCCAGCACTGA
TTCAGTAGCAGGCTTTACGCTACGTATAGTTAAAATAGCCGTTCTCTGGGTAATCTTCCTGACTGCATCAATATTACTTA
TACCTAGGTTACTTAACAGGATTAATGAATACCTAGTGGTCTACGCATCACTAATAGTGTTGTTTGGACTAGTGGTTTCA
ATGGTTGCCTCAGGCTTCTCAGCAGTAATAGCATCCTTCATAGCCGGTGTAGCGGTTGCGGAAAGCAGGGAGTCAGGTAG
GGTTAGGGCGTCTATTGACGCATTATTAGCCATATTTGGTTCAATATTCTTCATAACCATAGGCCTCCAAATGAACTTCA
AGACAATAACCAACTTAACGACTATCCTCCAATCCCTAATAGTATCAGCAATAGCAATTATAGCTAAGGTTATTGGAGTT
TACCCATTCGCCTACATTAAGTTAAGGAACACATCCGCCTCATTAACAGCATCACTAGGCATGGTGCCTAGGGGTGAAAT
GGGGTTGGTGATCGCCTCAATAGGCTTATCAAGCAGTCTACTAAACCCAAGTGAATACGGCTTAATACTAATAATGGTTC
TTGCAACCACAATAATTGGTTCAATACTATATAGGAGGAGCATTAGGCTTAACATTGAGGGGAATTAA

Upstream 100 bases:

>100_bases
AGTAGCCATGATTAGGGTTAGGCCGCGGACGGTTAAAGCTTTCCTCAATTAAGTTAAGTAGGGTTACGCTTTTAAGAATA
TTATAGAGCCGGTTAACGTA

Downstream 100 bases:

>100_bases
GGAGGTCACTCTGGAGTGTTAAAGGGCTATGTGGAAAACCAAGGAAAAGAGTAACATTATATAACTGCCCTTCAACCACA
AGATTTACCCAACTTAAAGA

Product: sodium/hydrogen exchanger

Products: Proton [Cytoplasm]; K (I) [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 394

Protein sequence:

>395_residues
MAVGSIYLTLLEFAILVTTAESLSLILAKYKYPSIVAELLTGIALSPYALGGLLNALLHVDLFSINNYVVFLSEFSVILL
LFASGLGHGLSSLKQGGFPGLMAAVAGAILPFMTVYWYCTSVGFSQVAASLIALSTAPTSLAVVANIIEREGLHELPSTK
VLVAAASVDDVVALILLSTLPTSPSTDSVAGFTLRIVKIAVLWVIFLTASILLIPRLLNRINEYLVVYASLIVLFGLVVS
MVASGFSAVIASFIAGVAVAESRESGRVRASIDALLAIFGSIFFITIGLQMNFKTITNLTTILQSLIVSAIAIIAKVIGV
YPFAYIKLRNTSASLTASLGMVPRGEMGLVIASIGLSSSLLNPSEYGLILIMVLATTIIGSILYRRSIRLNIEGN

Sequences:

>Translated_395_residues
MAVGSIYLTLLEFAILVTTAESLSLILAKYKYPSIVAELLTGIALSPYALGGLLNALLHVDLFSINNYVVFLSEFSVILL
LFASGLGHGLSSLKQGGFPGLMAAVAGAILPFMTVYWYCTSVGFSQVAASLIALSTAPTSLAVVANIIEREGLHELPSTK
VLVAAASVDDVVALILLSTLPTSPSTDSVAGFTLRIVKIAVLWVIFLTASILLIPRLLNRINEYLVVYASLIVLFGLVVS
MVASGFSAVIASFIAGVAVAESRESGRVRASIDALLAIFGSIFFITIGLQMNFKTITNLTTILQSLIVSAIAIIAKVIGV
YPFAYIKLRNTSASLTASLGMVPRGEMGLVIASIGLSSSLLNPSEYGLILIMVLATTIIGSILYRRSIRLNIEGN
>Mature_394_residues
AVGSIYLTLLEFAILVTTAESLSLILAKYKYPSIVAELLTGIALSPYALGGLLNALLHVDLFSINNYVVFLSEFSVILLL
FASGLGHGLSSLKQGGFPGLMAAVAGAILPFMTVYWYCTSVGFSQVAASLIALSTAPTSLAVVANIIEREGLHELPSTKV
LVAAASVDDVVALILLSTLPTSPSTDSVAGFTLRIVKIAVLWVIFLTASILLIPRLLNRINEYLVVYASLIVLFGLVVSM
VASGFSAVIASFIAGVAVAESRESGRVRASIDALLAIFGSIFFITIGLQMNFKTITNLTTILQSLIVSAIAIIAKVIGVY
PFAYIKLRNTSASLTASLGMVPRGEMGLVIASIGLSSSLLNPSEYGLILIMVLATTIIGSILYRRSIRLNIEGN

Specific function: This is a Na(+)/H(+) antiporter. It can mediate sodium uptake when a transmembrane pH gradient is applied [H]

COG id: COG0475

COG function: function code P; Kef-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR004771 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 41683; Mature: 41552

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVGSIYLTLLEFAILVTTAESLSLILAKYKYPSIVAELLTGIALSPYALGGLLNALLHV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHH
DLFSINNYVVFLSEFSVILLLFASGLGHGLSSLKQGGFPGLMAAVAGAILPFMTVYWYCT
HHEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
SVGFSQVAASLIALSTAPTSLAVVANIIEREGLHELPSTKVLVAAASVDDVVALILLSTL
HCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHHC
PTSPSTDSVAGFTLRIVKIAVLWVIFLTASILLIPRLLNRINEYLVVYASLIVLFGLVVS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MVASGFSAVIASFIAGVAVAESRESGRVRASIDALLAIFGSIFFITIGLQMNFKTITNLT
HHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEECHHHHHHHH
TILQSLIVSAIAIIAKVIGVYPFAYIKLRNTSASLTASLGMVPRGEMGLVIASIGLSSSL
HHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHCCCCCCCCCCEEEEECCCHHHC
LNPSEYGLILIMVLATTIIGSILYRRSIRLNIEGN
CCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCC
>Mature Secondary Structure 
AVGSIYLTLLEFAILVTTAESLSLILAKYKYPSIVAELLTGIALSPYALGGLLNALLHV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHH
DLFSINNYVVFLSEFSVILLLFASGLGHGLSSLKQGGFPGLMAAVAGAILPFMTVYWYCT
HHEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
SVGFSQVAASLIALSTAPTSLAVVANIIEREGLHELPSTKVLVAAASVDDVVALILLSTL
HCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHHC
PTSPSTDSVAGFTLRIVKIAVLWVIFLTASILLIPRLLNRINEYLVVYASLIVLFGLVVS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MVASGFSAVIASFIAGVAVAESRESGRVRASIDALLAIFGSIFFITIGLQMNFKTITNLT
HHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEECHHHHHHHH
TILQSLIVSAIAIIAKVIGVYPFAYIKLRNTSASLTASLGMVPRGEMGLVIASIGLSSSL
HHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHCCCCCCCCCCEEEEECCCHHHC
LNPSEYGLILIMVLATTIIGSILYRRSIRLNIEGN
CCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Cytoplasm] = Proton [Cytoplasm] + K (I) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1312090; 1325937 [H]