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The map label for this gene is nuoL [H]

Identifier: 159041845

GI number: 159041845

Start: 1348898

End: 1350871

Strand: Reverse

Name: nuoL [H]

Synonym: Cmaq_1280

Alternate gene names: 159041845

Gene position: 1350871-1348898 (Counterclockwise)

Preceding gene: 159041846

Following gene: 159041844

Centisome position: 65.02

GC content: 45.74

Gene sequence:

>1974_bases
ATGTATGAGTCCATTCTCCCCACCTTAATAGCCTTAATGACACTAGTGCCCATACTGTTTGCTTCACCAATGTCAGTGTA
CTGGGTTATTGAGCAGGATAACCGTAAGGCACGCCCACTGGAGTATCTTGCTGTGACTGGGCTTGGTGTGGCTGCATTAG
TTTCAACATACATAGCCATTGCGTACCCGATGAAGACCATTATTTACTCATACCCATGGATCTCGGTGCCAGGTATCTTC
ACAATGTACGTGTCATTCATAGTTGACTTCCTGAGCAGGTATATGGGGTTATTAACAGCTTGGCTTGCCTTCATAATAGG
TGTATACAGCCTGGAGTACATGGCTAATGACTATAGGCTTGGCTGGTTCTGGTTCTTCTACAACACCTTCGCAGCATCAA
TGCTACTGCTCGTTTACTCCAATAACCTACTCCTGTTGTTCATAGGGTGGGAGGGATTAGGTCTAAGTTCATGGGCGTTG
ATAGGTAATTGGTTCAGAGATGATGATGAAATATCCTTCGTTGGGAAGCTGGGTGACATGGTGCTTGGTAAGCCAGCGTG
GACTACACCATCCTACGCCGCCTATAGGGCTATTGTTACAATAAGGTTCGGTGACATGCCCATGCTGGGTGCCTTAGCGG
CAATAGGGATATTTGGAGGCAGCCTAGACTTCAATATGATAAACTGGAGTCACTTAATAAGCGTACTGGGTACCGCTGGA
ACAGCCATAGTTCTCATCGCCTTCCTGCTTGGCCCATTCACTAAGAGCGCTCAATTCCCATTCAATGACTGGCTCCTCAC
AGCCATGACTGGTCCAACCAGTGTTTCCGCATTACTTCACTCAGCCACAATGGTTGCTGCAGGTGTTTACGTATTCATGA
GACTTACCCTATCCCTATACGGTGCAGGGGTGTTAACATCAAGTGGAGTATTGGTAACCTACCTGGTGGTTATCTATATT
GGTTTACTAACAGCCTTACTTGGTTCATTATTCGCCTTAGCCGTTGATGAGAGGAAAGTTATCCTAGCTGGTTCAACCAT
GGCGTCACTGGGGTTAATGATGGGTATAACCGCTGTTGCACCTTACTTAAACAATGCAGTAACCATCGGTGAGTACGTGC
TTCCTACAGCTGTACTGGTTGCCTTCCTATACTTAATAATACACGCCTTATCTAAGGCTACATTATTCCTAGTCAGTGGT
CACTTGATTCATGAGACTGGGACCAGGTTTAATGTGGGTGATGTTGAGTTGGCTAAGAGGATGAAACTAGCCTTCTACTC
AACAATAGCCGCTGCAATAACCCTGGGAGGCATTCCACCGTTTGCCGGTTACTGGGTTCACGCCTCAATGGATGACTTAG
TCTCCACTGTGAGTCAAACAGTGGGCTGGGGTTCATATGCACTACTGATACTTGCAAGCATAGCCTACGTAGCCTTCCTA
GCCAGATTCACTTCCCTCAACTTCATTAAGGGGGGTAGGGTGGAGCATAGGGAGTCTGGGCACGGTGGATTAATAATGGC
TATATCATACACCTTAACGGCCACAGTGGCCCTAGCCACAGTGGCAATACCATTTACTCTACATGTACCATCAATACTGG
TTGAACCTGGCTATGATGCGTATGTAGTGGGTATTGGTGTATTCCTCTGGGTAATCTTCATTACCGCGCTTATTAAACCA
AGGGCACCATCATTAAGTAATTTAACAACCATTTTTGAACGTAGGTATTACATACAGGCATTCATGGATGTTATCCTAGC
GGGCTTTGGGAGAGCCCTCATAGAGTTCGCCTACTTAATAAGCCATGGAATTGATGTACTCTTCAACACGCTTATACCAT
CATTGTTCACAGGTTTCTCAAGGGTTATTAGGAGGATTCAGGTTGGTTTACTGAACCAGTACGTTAGGTACATTTACCTG
GCGACTGTGGTAATACTATTAATAGTATTGGTGCTGGTGATGGTGTATGGTTGA

Upstream 100 bases:

>100_bases
CCGCTTTACGTACTTGGTTTAACAAGCGTCATACTACTATTCCCACCCATATCAACAGCATTAGTTCACTCAGTACTAAG
TGCAATAGGGGTGATAATGC

Downstream 100 bases:

>100_bases
GTACATTGATATCATAGTCTCATCAGTAATAGGGACAATATTAGTTACAGCCGCATTACTGGCCTTTAAGAGGGAGGAGT
ACGCTTGGATACCTGCAATA

Product: NADH dehydrogenase (quinone)

Products: NA

Alternate protein names: NADH dehydrogenase I subunit L; NDH-1 subunit L [H]

Number of amino acids: Translated: 657; Mature: 657

Protein sequence:

>657_residues
MYESILPTLIALMTLVPILFASPMSVYWVIEQDNRKARPLEYLAVTGLGVAALVSTYIAIAYPMKTIIYSYPWISVPGIF
TMYVSFIVDFLSRYMGLLTAWLAFIIGVYSLEYMANDYRLGWFWFFYNTFAASMLLLVYSNNLLLLFIGWEGLGLSSWAL
IGNWFRDDDEISFVGKLGDMVLGKPAWTTPSYAAYRAIVTIRFGDMPMLGALAAIGIFGGSLDFNMINWSHLISVLGTAG
TAIVLIAFLLGPFTKSAQFPFNDWLLTAMTGPTSVSALLHSATMVAAGVYVFMRLTLSLYGAGVLTSSGVLVTYLVVIYI
GLLTALLGSLFALAVDERKVILAGSTMASLGLMMGITAVAPYLNNAVTIGEYVLPTAVLVAFLYLIIHALSKATLFLVSG
HLIHETGTRFNVGDVELAKRMKLAFYSTIAAAITLGGIPPFAGYWVHASMDDLVSTVSQTVGWGSYALLILASIAYVAFL
ARFTSLNFIKGGRVEHRESGHGGLIMAISYTLTATVALATVAIPFTLHVPSILVEPGYDAYVVGIGVFLWVIFITALIKP
RAPSLSNLTTIFERRYYIQAFMDVILAGFGRALIEFAYLISHGIDVLFNTLIPSLFTGFSRVIRRIQVGLLNQYVRYIYL
ATVVILLIVLVLVMVYG

Sequences:

>Translated_657_residues
MYESILPTLIALMTLVPILFASPMSVYWVIEQDNRKARPLEYLAVTGLGVAALVSTYIAIAYPMKTIIYSYPWISVPGIF
TMYVSFIVDFLSRYMGLLTAWLAFIIGVYSLEYMANDYRLGWFWFFYNTFAASMLLLVYSNNLLLLFIGWEGLGLSSWAL
IGNWFRDDDEISFVGKLGDMVLGKPAWTTPSYAAYRAIVTIRFGDMPMLGALAAIGIFGGSLDFNMINWSHLISVLGTAG
TAIVLIAFLLGPFTKSAQFPFNDWLLTAMTGPTSVSALLHSATMVAAGVYVFMRLTLSLYGAGVLTSSGVLVTYLVVIYI
GLLTALLGSLFALAVDERKVILAGSTMASLGLMMGITAVAPYLNNAVTIGEYVLPTAVLVAFLYLIIHALSKATLFLVSG
HLIHETGTRFNVGDVELAKRMKLAFYSTIAAAITLGGIPPFAGYWVHASMDDLVSTVSQTVGWGSYALLILASIAYVAFL
ARFTSLNFIKGGRVEHRESGHGGLIMAISYTLTATVALATVAIPFTLHVPSILVEPGYDAYVVGIGVFLWVIFITALIKP
RAPSLSNLTTIFERRYYIQAFMDVILAGFGRALIEFAYLISHGIDVLFNTLIPSLFTGFSRVIRRIQVGLLNQYVRYIYL
ATVVILLIVLVLVMVYG
>Mature_657_residues
MYESILPTLIALMTLVPILFASPMSVYWVIEQDNRKARPLEYLAVTGLGVAALVSTYIAIAYPMKTIIYSYPWISVPGIF
TMYVSFIVDFLSRYMGLLTAWLAFIIGVYSLEYMANDYRLGWFWFFYNTFAASMLLLVYSNNLLLLFIGWEGLGLSSWAL
IGNWFRDDDEISFVGKLGDMVLGKPAWTTPSYAAYRAIVTIRFGDMPMLGALAAIGIFGGSLDFNMINWSHLISVLGTAG
TAIVLIAFLLGPFTKSAQFPFNDWLLTAMTGPTSVSALLHSATMVAAGVYVFMRLTLSLYGAGVLTSSGVLVTYLVVIYI
GLLTALLGSLFALAVDERKVILAGSTMASLGLMMGITAVAPYLNNAVTIGEYVLPTAVLVAFLYLIIHALSKATLFLVSG
HLIHETGTRFNVGDVELAKRMKLAFYSTIAAAITLGGIPPFAGYWVHASMDDLVSTVSQTVGWGSYALLILASIAYVAFL
ARFTSLNFIKGGRVEHRESGHGGLIMAISYTLTATVALATVAIPFTLHVPSILVEPGYDAYVVGIGVFLWVIFITALIKP
RAPSLSNLTTIFERRYYIQAFMDVILAGFGRALIEFAYLISHGIDVLFNTLIPSLFTGFSRVIRRIQVGLLNQYVRYIYL
ATVVILLIVLVLVMVYG

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be menaquinone. Couples the redox reaction to proton transloca

COG id: COG1009

COG function: function code CP; NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 5 family [H]

Homologues:

Organism=Homo sapiens, GI251831117, Length=448, Percent_Identity=29.9107142857143, Blast_Score=139, Evalue=7e-33,
Organism=Escherichia coli, GI1788614, Length=419, Percent_Identity=31.5035799522673, Blast_Score=133, Evalue=3e-32,
Organism=Escherichia coli, GI1788829, Length=367, Percent_Identity=26.158038147139, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788827, Length=371, Percent_Identity=28.5714285714286, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1788831, Length=367, Percent_Identity=25.8855585831063, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001750
- InterPro:   IPR001516
- InterPro:   IPR003945
- InterPro:   IPR018393 [H]

Pfam domain/function: PF00361 Oxidored_q1; PF00662 Oxidored_q1_N [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 71890; Mature: 71890

Theoretical pI: Translated: 8.39; Mature: 8.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYESILPTLIALMTLVPILFASPMSVYWVIEQDNRKARPLEYLAVTGLGVAALVSTYIAI
CCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHCCHHHHHHHHHHHH
AYPMKTIIYSYPWISVPGIFTMYVSFIVDFLSRYMGLLTAWLAFIIGVYSLEYMANDYRL
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
GWFWFFYNTFAASMLLLVYSNNLLLLFIGWEGLGLSSWALIGNWFRDDDEISFVGKLGDM
HHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHH
VLGKPAWTTPSYAAYRAIVTIRFGDMPMLGALAAIGIFGGSLDFNMINWSHLISVLGTAG
HCCCCCCCCCCHHHEEEEEEEEECCCCHHHHHHHHHHHCCCCCEEEECHHHHHHHHHCCH
TAIVLIAFLLGPFTKSAQFPFNDWLLTAMTGPTSVSALLHSATMVAAGVYVFMRLTLSLY
HHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAGVLTSSGVLVTYLVVIYIGLLTALLGSLFALAVDERKVILAGSTMASLGLMMGITAVA
CCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHH
PYLNNAVTIGEYVLPTAVLVAFLYLIIHALSKATLFLVSGHLIHETGTRFNVGDVELAKR
HHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECEEEECCCCCCCCCHHHHHHH
MKLAFYSTIAAAITLGGIPPFAGYWVHASMDDLVSTVSQTVGWGSYALLILASIAYVAFL
HHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
ARFTSLNFIKGGRVEHRESGHGGLIMAISYTLTATVALATVAIPFTLHVPSILVEPGYDA
HHHHHCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHEEECCHHEECCCCCH
YVVGIGVFLWVIFITALIKPRAPSLSNLTTIFERRYYIQAFMDVILAGFGRALIEFAYLI
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SHGIDVLFNTLIPSLFTGFSRVIRRIQVGLLNQYVRYIYLATVVILLIVLVLVMVYG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MYESILPTLIALMTLVPILFASPMSVYWVIEQDNRKARPLEYLAVTGLGVAALVSTYIAI
CCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHCCHHHHHHHHHHHH
AYPMKTIIYSYPWISVPGIFTMYVSFIVDFLSRYMGLLTAWLAFIIGVYSLEYMANDYRL
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
GWFWFFYNTFAASMLLLVYSNNLLLLFIGWEGLGLSSWALIGNWFRDDDEISFVGKLGDM
HHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHH
VLGKPAWTTPSYAAYRAIVTIRFGDMPMLGALAAIGIFGGSLDFNMINWSHLISVLGTAG
HCCCCCCCCCCHHHEEEEEEEEECCCCHHHHHHHHHHHCCCCCEEEECHHHHHHHHHCCH
TAIVLIAFLLGPFTKSAQFPFNDWLLTAMTGPTSVSALLHSATMVAAGVYVFMRLTLSLY
HHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAGVLTSSGVLVTYLVVIYIGLLTALLGSLFALAVDERKVILAGSTMASLGLMMGITAVA
CCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHH
PYLNNAVTIGEYVLPTAVLVAFLYLIIHALSKATLFLVSGHLIHETGTRFNVGDVELAKR
HHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECEEEECCCCCCCCCHHHHHHH
MKLAFYSTIAAAITLGGIPPFAGYWVHASMDDLVSTVSQTVGWGSYALLILASIAYVAFL
HHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
ARFTSLNFIKGGRVEHRESGHGGLIMAISYTLTATVALATVAIPFTLHVPSILVEPGYDA
HHHHHCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHEEECCHHEECCCCCH
YVVGIGVFLWVIFITALIKPRAPSLSNLTTIFERRYYIQAFMDVILAGFGRALIEFAYLI
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SHGIDVLFNTLIPSLFTGFSRVIRRIQVGLLNQYVRYIYLATVVILLIVLVLVMVYG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10688204 [H]