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The map label for this gene is nuoN [H]

Identifier: 159041846

GI number: 159041846

Start: 1350864

End: 1352330

Strand: Reverse

Name: nuoN [H]

Synonym: Cmaq_1281

Alternate gene names: 159041846

Gene position: 1352330-1350864 (Counterclockwise)

Preceding gene: 159041847

Following gene: 159041845

Centisome position: 65.09

GC content: 42.47

Gene sequence:

>1467_bases
ATGATGGTTTACATGGATCCAATCCTCATATTCTCACTATCACTCCCAATTGCAGCAGTTATATTAACCGCGTTTTTAAA
TAAACGTGCATCACTCTATACTGCCGTAATATCATTTATGCCGTTAATAGCCTACTCACTATACGGCATATTCGCTAACC
TTGATTACCTGGTTCCACTTGGTAGCTTACCAAGCCCAATAGGCGGCATGTACCTTATTAACGATGGTTTAAGTAATTCA
TTCGGCTTCACAATAGCCTTAGTCACAGCCATGATATCCATAGTCTCTGAACCGTACATGGAGCATAGGTTCCGTGCATT
GGGTATTAAGGAGGAGTTCAACATATATTACCCATTATTCATACTATGCGGCATATCAATGGAGTGGATAGTGTACGCAT
ATAATCTACTCCTCATGTACATAGGCCTTGAAGTATCCTTAATATCATCATTCCTCCTAATATACTTCTACGGTTATGAC
GGCTACGGGAGAACTAGACAGTGGATAGGCTTACTTTACTTCGTCTATACCCACGTCGCCAGTGTACTATTCCTAGTGGG
TGCAATTATAGTTGCATTAACTAATGGGACAATGAACCTAGCCGCAATAAAGTACGTGCCACCTGTGGCCTGGGTCTTAA
TACTAATCGGCATGTTGATAAAGCTACCAAGCTATGGCCCACACGTTTGGTTACCTTGGGCGCACGGCATGCATCCAACA
CCGGTTGCAGCATTAATAATATCAGTTGTTGGCTTAGCATCATACATACTGGCTAGAATATACTTAATATCACCGTACTT
CATAACATCAATTAGGACACCATTACTTGCCTACGCCATAATAGGTGGCATATTAGTTAGCTTCGCTGTATTTAGGCAGA
GACATAGCTACAAGTGGTTACTGGCTTACTCAACTGTGGCTAACATGGCTTACCTACTGGCTGGTTTAACACTAGGTACA
TATGGTATAGTGGGCTTAACACTACACTTCATTGCGCATCAATTAGGTAAGGCAGTCCTCTTCATGACTGCTGGGGCAAT
TATTGTTCAATATGATATACTTGATATGTCTAAGATGGGTGGACTCCAGAACTACATACCATCAATAGGCGGTGCGGCAT
TGCTTGGTTGGATGAGCTTAGCAGGCATATTCACTGTTGGGTTACTGGGTGAATTCTTCCTATTCCTAGGCCTATTAACA
ACACTAGGCTTCAGTCTAAGCACTCTATGGGCCTTCGTGGGTTTAGCATTCCTATTCCTGCTAACTGGAACATACGGCTT
CTGGGCACTTAAGGAAGTCTTCTATGGACAACCAAGGTGGCCTTACACTAAAACTAAGCCAAGTAATAAGCTGGTGGTGC
CGCTTTACGTACTTGGTTTAACAAGCGTCATACTACTATTCCCACCCATATCAACAGCATTAGTTCACTCAGTACTAAGT
GCAATAGGGGTGATAATGCATGTATGA

Upstream 100 bases:

>100_bases
CGGCTGCTGAATTCATAGCATTAATAACTGCAATCATAACTGTGGATAGAATGAGGAGGAGTATTGAGACGAGGAGTATT
TTAGCTGGGGGTGATAGGTC

Downstream 100 bases:

>100_bases
GTCCATTCTCCCCACCTTAATAGCCTTAATGACACTAGTGCCCATACTGTTTGCTTCACCAATGTCAGTGTACTGGGTTA
TTGAGCAGGATAACCGTAAG

Product: NADH/ubiquinone/plastoquinone (complex I)

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N [H]

Number of amino acids: Translated: 488; Mature: 488

Protein sequence:

>488_residues
MMVYMDPILIFSLSLPIAAVILTAFLNKRASLYTAVISFMPLIAYSLYGIFANLDYLVPLGSLPSPIGGMYLINDGLSNS
FGFTIALVTAMISIVSEPYMEHRFRALGIKEEFNIYYPLFILCGISMEWIVYAYNLLLMYIGLEVSLISSFLLIYFYGYD
GYGRTRQWIGLLYFVYTHVASVLFLVGAIIVALTNGTMNLAAIKYVPPVAWVLILIGMLIKLPSYGPHVWLPWAHGMHPT
PVAALIISVVGLASYILARIYLISPYFITSIRTPLLAYAIIGGILVSFAVFRQRHSYKWLLAYSTVANMAYLLAGLTLGT
YGIVGLTLHFIAHQLGKAVLFMTAGAIIVQYDILDMSKMGGLQNYIPSIGGAALLGWMSLAGIFTVGLLGEFFLFLGLLT
TLGFSLSTLWAFVGLAFLFLLTGTYGFWALKEVFYGQPRWPYTKTKPSNKLVVPLYVLGLTSVILLFPPISTALVHSVLS
AIGVIMHV

Sequences:

>Translated_488_residues
MMVYMDPILIFSLSLPIAAVILTAFLNKRASLYTAVISFMPLIAYSLYGIFANLDYLVPLGSLPSPIGGMYLINDGLSNS
FGFTIALVTAMISIVSEPYMEHRFRALGIKEEFNIYYPLFILCGISMEWIVYAYNLLLMYIGLEVSLISSFLLIYFYGYD
GYGRTRQWIGLLYFVYTHVASVLFLVGAIIVALTNGTMNLAAIKYVPPVAWVLILIGMLIKLPSYGPHVWLPWAHGMHPT
PVAALIISVVGLASYILARIYLISPYFITSIRTPLLAYAIIGGILVSFAVFRQRHSYKWLLAYSTVANMAYLLAGLTLGT
YGIVGLTLHFIAHQLGKAVLFMTAGAIIVQYDILDMSKMGGLQNYIPSIGGAALLGWMSLAGIFTVGLLGEFFLFLGLLT
TLGFSLSTLWAFVGLAFLFLLTGTYGFWALKEVFYGQPRWPYTKTKPSNKLVVPLYVLGLTSVILLFPPISTALVHSVLS
AIGVIMHV
>Mature_488_residues
MMVYMDPILIFSLSLPIAAVILTAFLNKRASLYTAVISFMPLIAYSLYGIFANLDYLVPLGSLPSPIGGMYLINDGLSNS
FGFTIALVTAMISIVSEPYMEHRFRALGIKEEFNIYYPLFILCGISMEWIVYAYNLLLMYIGLEVSLISSFLLIYFYGYD
GYGRTRQWIGLLYFVYTHVASVLFLVGAIIVALTNGTMNLAAIKYVPPVAWVLILIGMLIKLPSYGPHVWLPWAHGMHPT
PVAALIISVVGLASYILARIYLISPYFITSIRTPLLAYAIIGGILVSFAVFRQRHSYKWLLAYSTVANMAYLLAGLTLGT
YGIVGLTLHFIAHQLGKAVLFMTAGAIIVQYDILDMSKMGGLQNYIPSIGGAALLGWMSLAGIFTVGLLGEFFLFLGLLT
TLGFSLSTLWAFVGLAFLFLLTGTYGFWALKEVFYGQPRWPYTKTKPSNKLVVPLYVLGLTSVILLFPPISTALVHSVLS
AIGVIMHV

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translo

COG id: COG0651

COG function: function code CP; Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831117, Length=351, Percent_Identity=27.0655270655271, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI251831116, Length=369, Percent_Identity=25.7452574525745, Blast_Score=71, Evalue=3e-12,
Organism=Escherichia coli, GI1788831, Length=321, Percent_Identity=28.3489096573209, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788614, Length=329, Percent_Identity=31.0030395136778, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788827, Length=336, Percent_Identity=27.0833333333333, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010096
- InterPro:   IPR001750
- InterPro:   IPR003918 [H]

Pfam domain/function: PF00361 Oxidored_q1 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 53805; Mature: 53805

Theoretical pI: Translated: 9.33; Mature: 9.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMVYMDPILIFSLSLPIAAVILTAFLNKRASLYTAVISFMPLIAYSLYGIFANLDYLVPL
CEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEC
GSLPSPIGGMYLINDGLSNSFGFTIALVTAMISIVSEPYMEHRFRALGIKEEFNIYYPLF
CCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHCCCHHHCCHHHHHH
ILCGISMEWIVYAYNLLLMYIGLEVSLISSFLLIYFYGYDGYGRTRQWIGLLYFVYTHVA
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
SVLFLVGAIIVALTNGTMNLAAIKYVPPVAWVLILIGMLIKLPSYGPHVWLPWAHGMHPT
HHHHHHHHHHHHHCCCCCEEEEEHHCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCC
PVAALIISVVGLASYILARIYLISPYFITSIRTPLLAYAIIGGILVSFAVFRQRHSYKWL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
LAYSTVANMAYLLAGLTLGTYGIVGLTLHFIAHQLGKAVLFMTAGAIIVQYDILDMSKMG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEEHHHHHHHC
GLQNYIPSIGGAALLGWMSLAGIFTVGLLGEFFLFLGLLTTLGFSLSTLWAFVGLAFLFL
CHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTGTYGFWALKEVFYGQPRWPYTKTKPSNKLVVPLYVLGLTSVILLFPPISTALVHSVLS
HHCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCHHHHHHHHHHH
AIGVIMHV
HHHHHHCC
>Mature Secondary Structure
MMVYMDPILIFSLSLPIAAVILTAFLNKRASLYTAVISFMPLIAYSLYGIFANLDYLVPL
CEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEC
GSLPSPIGGMYLINDGLSNSFGFTIALVTAMISIVSEPYMEHRFRALGIKEEFNIYYPLF
CCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHCCCHHHCCHHHHHH
ILCGISMEWIVYAYNLLLMYIGLEVSLISSFLLIYFYGYDGYGRTRQWIGLLYFVYTHVA
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
SVLFLVGAIIVALTNGTMNLAAIKYVPPVAWVLILIGMLIKLPSYGPHVWLPWAHGMHPT
HHHHHHHHHHHHHCCCCCEEEEEHHCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCC
PVAALIISVVGLASYILARIYLISPYFITSIRTPLLAYAIIGGILVSFAVFRQRHSYKWL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
LAYSTVANMAYLLAGLTLGTYGIVGLTLHFIAHQLGKAVLFMTAGAIIVQYDILDMSKMG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEEHHHHHHHC
GLQNYIPSIGGAALLGWMSLAGIFTVGLLGEFFLFLGLLTTLGFSLSTLWAFVGLAFLFL
CHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTGTYGFWALKEVFYGQPRWPYTKTKPSNKLVVPLYVLGLTSVILLFPPISTALVHSVLS
HHCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCHHHHHHHHHHH
AIGVIMHV
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA