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The map label for this gene is mthK [H]

Identifier: 159041558

GI number: 159041558

Start: 1042311

End: 1043345

Strand: Reverse

Name: mthK [H]

Synonym: Cmaq_0989

Alternate gene names: 159041558

Gene position: 1043345-1042311 (Counterclockwise)

Preceding gene: 159041559

Following gene: 159041557

Centisome position: 50.22

GC content: 39.71

Gene sequence:

>1035_bases
ATGCCTATTATACAATTGAATGTGTATAGGCTAATGAGGAGGATTAGGAGAGTGTTGAGAAGCCTAGTAGTTTACGTAAT
ATTAATGTTTATGGCTGTGTTGTTCATAGGTGCATTAGGCATTTATCTGGTTGAGCATGGTCATAACCCTGGTATTAGGA
ACTTTTTCGATGCCATTTGGTTCGTCATGGAGACTATAACCACCGTGGGTTACGGGGATATTGTTCCTCAAACCACTGTG
GGTAGGGTTTTGGATATGGTTATAATGCCAATTGGTATAGCGGTAATAAGCATATTAACAGCATCAATAGCCACCTTATT
AACTGAGAGGGCTATGGAGAAGATGGGTGGTATGAAGTCAAGCAGTAAGGGTAATCATGTGGTTATTCTGGGTGAGCCTG
AGAGGGCTATCAACTTAATTAAGGCTTTGATTAAATTAATGGATGAGTCAGGTAAATTCATTGATATAGTTTACGTAAGT
GAATTTGAAAAACCACCTAACTTACCTAAGGATGTTGAATTCATTAAGGGTAACCCAACGCTTAAGGATACTTTAATTAG
GGCTAATGTTGATAAGGCATCATCACTAATAATCCTACCCCAGGGGGATTCTGCTTCAGCGGATGCTAGGACACTTATGG
AGGTTGTGGTGGCTAGGAGCATTAACCCAAGCCTCTACATAGTGGCTGAGCTCCTCAATGAGGGTAATGCGGAGTATGTA
CTTAAGGCTGGAGCCGATGAAGCAATAGCCGTGGGGTCATTAACAACAATAGCTATGGCGAATGAAATCATTTATAGGGG
ATCATTAAAGGCAATAATGAGGCTACTTAGAGGTAACAGTGAAATCTTAGTTATTAACTCAAGCAAGTACACTGGGTTGA
GTTTCAAGGATGCCCTCATTAGGGTGAGGGAAGATGAGTCGGGAATACTCATTGGTGTTCTCAGAAATAATGAGGTGTTA
ATAAGCCCAAGTGATGAACTAATTATTAAACCAGGTGATGAATTAATAATAATTAAATCAATGAACATTAAGTAG

Upstream 100 bases:

>100_bases
AAACCACCGGTTCATACTAGGATGCTTAATGTTAGGTTAAGTTTCTATAATGGTAACGCTAATTAAGCATTATTAGAGGG
GATGCTACTATGGGTTTAGT

Downstream 100 bases:

>100_bases
ATGCAGCAGCCTAACCTTAATTAAGTGTATACCTGGGGAGTTAATGGAAATATAAATATTGAGGGTAAACCTTAAAACTC
ACTAAGTTGCATTGAAGGTA

Product: Ion transport 2 domain-containing protein

Products: K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MPIIQLNVYRLMRRIRRVLRSLVVYVILMFMAVLFIGALGIYLVEHGHNPGIRNFFDAIWFVMETITTVGYGDIVPQTTV
GRVLDMVIMPIGIAVISILTASIATLLTERAMEKMGGMKSSSKGNHVVILGEPERAINLIKALIKLMDESGKFIDIVYVS
EFEKPPNLPKDVEFIKGNPTLKDTLIRANVDKASSLIILPQGDSASADARTLMEVVVARSINPSLYIVAELLNEGNAEYV
LKAGADEAIAVGSLTTIAMANEIIYRGSLKAIMRLLRGNSEILVINSSKYTGLSFKDALIRVREDESGILIGVLRNNEVL
ISPSDELIIKPGDELIIIKSMNIK

Sequences:

>Translated_344_residues
MPIIQLNVYRLMRRIRRVLRSLVVYVILMFMAVLFIGALGIYLVEHGHNPGIRNFFDAIWFVMETITTVGYGDIVPQTTV
GRVLDMVIMPIGIAVISILTASIATLLTERAMEKMGGMKSSSKGNHVVILGEPERAINLIKALIKLMDESGKFIDIVYVS
EFEKPPNLPKDVEFIKGNPTLKDTLIRANVDKASSLIILPQGDSASADARTLMEVVVARSINPSLYIVAELLNEGNAEYV
LKAGADEAIAVGSLTTIAMANEIIYRGSLKAIMRLLRGNSEILVINSSKYTGLSFKDALIRVREDESGILIGVLRNNEVL
ISPSDELIIKPGDELIIIKSMNIK
>Mature_343_residues
PIIQLNVYRLMRRIRRVLRSLVVYVILMFMAVLFIGALGIYLVEHGHNPGIRNFFDAIWFVMETITTVGYGDIVPQTTVG
RVLDMVIMPIGIAVISILTASIATLLTERAMEKMGGMKSSSKGNHVVILGEPERAINLIKALIKLMDESGKFIDIVYVSE
FEKPPNLPKDVEFIKGNPTLKDTLIRANVDKASSLIILPQGDSASADARTLMEVVVARSINPSLYIVAELLNEGNAEYVL
KAGADEAIAVGSLTTIAMANEIIYRGSLKAIMRLLRGNSEILVINSSKYTGLSFKDALIRVREDESGILIGVLRNNEVLI
SPSDELIIKPGDELIIIKSMNIK

Specific function: Calcium-gated potassium channel [H]

COG id: COG1226

COG function: function code P; Kef-type K+ transport systems, predicted NAD-binding component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI238624130, Length=363, Percent_Identity=23.6914600550964, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI26638650, Length=363, Percent_Identity=23.6914600550964, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI238624132, Length=363, Percent_Identity=23.6914600550964, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI62388890, Length=321, Percent_Identity=24.2990654205607, Blast_Score=79, Evalue=5e-15,
Organism=Escherichia coli, GI1787503, Length=225, Percent_Identity=24, Blast_Score=74, Evalue=2e-14,
Organism=Drosophila melanogaster, GI62472818, Length=257, Percent_Identity=25.2918287937743, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI62472824, Length=257, Percent_Identity=25.2918287937743, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI62472908, Length=257, Percent_Identity=25.2918287937743, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI62472912, Length=257, Percent_Identity=24.9027237354086, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI281362477, Length=257, Percent_Identity=24.5136186770428, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI281362479, Length=257, Percent_Identity=24.124513618677, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI45553505, Length=257, Percent_Identity=24.124513618677, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24649751, Length=257, Percent_Identity=24.124513618677, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI62472831, Length=257, Percent_Identity=24.124513618677, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI62472836, Length=257, Percent_Identity=24.124513618677, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI62472846, Length=257, Percent_Identity=24.124513618677, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI62472866, Length=257, Percent_Identity=24.124513618677, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI62472881, Length=257, Percent_Identity=24.124513618677, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI62472886, Length=257, Percent_Identity=24.124513618677, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24649749, Length=257, Percent_Identity=24.124513618677, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI62472875, Length=257, Percent_Identity=24.124513618677, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI62472858, Length=257, Percent_Identity=24.124513618677, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013099
- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148 [H]

Pfam domain/function: PF07885 Ion_trans_2; PF02080 TrkA_C; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 37823; Mature: 37692

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIIQLNVYRLMRRIRRVLRSLVVYVILMFMAVLFIGALGIYLVEHGHNPGIRNFFDAIW
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHH
FVMETITTVGYGDIVPQTTVGRVLDMVIMPIGIAVISILTASIATLLTERAMEKMGGMKS
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SSKGNHVVILGEPERAINLIKALIKLMDESGKFIDIVYVSEFEKPPNLPKDVEFIKGNPT
CCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCEEECCCCC
LKDTLIRANVDKASSLIILPQGDSASADARTLMEVVVARSINPSLYIVAELLNEGNAEYV
HHHHHEECCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEE
LKAGADEAIAVGSLTTIAMANEIIYRGSLKAIMRLLRGNSEILVINSSKYTGLSFKDALI
EECCCCCEEECCCHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHE
RVREDESGILIGVLRNNEVLISPSDELIIKPGDELIIIKSMNIK
EEEECCCCEEEEEEECCEEEECCCCCEEEECCCCEEEEEECCCC
>Mature Secondary Structure 
PIIQLNVYRLMRRIRRVLRSLVVYVILMFMAVLFIGALGIYLVEHGHNPGIRNFFDAIW
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHH
FVMETITTVGYGDIVPQTTVGRVLDMVIMPIGIAVISILTASIATLLTERAMEKMGGMKS
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SSKGNHVVILGEPERAINLIKALIKLMDESGKFIDIVYVSEFEKPPNLPKDVEFIKGNPT
CCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCEEECCCCC
LKDTLIRANVDKASSLIILPQGDSASADARTLMEVVVARSINPSLYIVAELLNEGNAEYV
HHHHHEECCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEE
LKAGADEAIAVGSLTTIAMANEIIYRGSLKAIMRLLRGNSEILVINSSKYTGLSFKDALI
EECCCCCEEECCCHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHE
RVREDESGILIGVLRNNEVLISPSDELIIKPGDELIIIKSMNIK
EEEECCCCEEEEEEECCEEEECCCCCEEEECCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9371463; 12037559 [H]