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The map label for this gene is tdcB [H]

Identifier: 159041515

GI number: 159041515

Start: 991528

End: 992784

Strand: Reverse

Name: tdcB [H]

Synonym: Cmaq_0945

Alternate gene names: 159041515

Gene position: 992784-991528 (Counterclockwise)

Preceding gene: 159041516

Following gene: 159041506

Centisome position: 47.79

GC content: 42.16

Gene sequence:

>1257_bases
ATTCTATCTGGTGAATTATATATCACAAGGGTTAATGAGGTCTACGAACTCAGTAGGGAGGCTTTAACCCTCATTAAGGA
TGCTCAAGCCAAGGGTATAATACATAGAACACCCCTCTATAGATCCGATACATTAAGTTCATTAACCAATGCCGATGTTT
ACCTTAAACTTGAGGCACTTCAAAAAACTGGGTCATTCAAGGTTAGAGGCGCCTACAACGCTGTAACACACTATATTAAT
GATGACGTTAAGCATGTTGTCACTGCATCAGCTGGTAATCATGCTCAAGGCGTTGCATACGTCGCTAAGATATATGGCTT
GAAGTCTACGATAGTGATGCCTAAGTACACGCCGTGGATTAAAATAAGCAATACCAGGAAGTATGGTGCAGAAGTCATAC
TTGAGGGTCAATCTTACTATGAGGCTGAGAAGTATGCTATAGAGTTAACTAAGGAGCTTAAGGCAAAAATGATCCATGCA
TATGATGATCCATTCGTTATTGCTGGACAGGGAACAATAGGGTGGGAAATTATTGAGGATCTTAAGAATATTGACTACGT
AATAGTCCCAGTGGGCGGTGGGGGATTAATATCAGGTATCGCCTCAGTTATTAAGACTATTAGCCCAAACACTAGGGTGA
TTGGGGTGCAGAGCGAGATAACTCCCTCAGCATACTTATCCCTTAAGCAAGGTAAGATCATTACGGTAGAGAACACGGAC
ACTATCGCTGATGGTATAGCTGTTAAGAAGATTGGGGACTTAACCTTCGATATAATGCGGAATACGCTTGATGATGTGGT
TTTAGTCAGTGACCAGGAAATAGTTAACGCCATACTAATATTGGCCGAGTCAGCCAAGGTTATAGCTGAGGGGGCTGGAG
CAGCTGCTGTAGCTGCGTTACTGAGCGGTAAAATTAACGTTAAGGGTAATGTGGTGGCTGTTGTTAGTGGAGGTAATATT
GATGTCACGATGCTTGCCAAGGTCCTTTACAAGGGACTTGTTCAAACAGGGAGATTAATTATGCTTAAGGGACTTATACC
AGATAGGCCAGGTATGCTTGCCCAGGTAACTGGTGTTCTAGGTAGGCTGGGGGTTAATATTGTTGAAATTAGGCATGAGA
GGTATAACCCATTAATAAGACCCAATTACACTGAGGTAGATGTAATAGTTGAAACACCACCTGAGGAGGGAGCTGTAGAT
AGGGTTATTGAGGAATTAAGTAGATTAGGCTTCAACTTTAAGGTTGAAGTGCCTTAA

Upstream 100 bases:

>100_bases
TTGGGTATTAAAAAATCAACCTTAAGAAGGATACTGAGGGTCACGAAACCCAGTACCTCTACTAAACCTACCCAGCAATA
AATATAAACTAGGGTTCTTT

Downstream 100 bases:

>100_bases
TTCTGAGTTTAAATATGAAGTAATGCCGGGATCACGAATATTGCTAACATTAGATTAATGAAAACGATAATAGTTATCAC
CACGTAAATCCAGTCCTTCT

Product: threonine dehydratase

Products: NA

Alternate protein names: Threonine deaminase [H]

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MLSGELYITRVNEVYELSREALTLIKDAQAKGIIHRTPLYRSDTLSSLTNADVYLKLEALQKTGSFKVRGAYNAVTHYIN
DDVKHVVTASAGNHAQGVAYVAKIYGLKSTIVMPKYTPWIKISNTRKYGAEVILEGQSYYEAEKYAIELTKELKAKMIHA
YDDPFVIAGQGTIGWEIIEDLKNIDYVIVPVGGGGLISGIASVIKTISPNTRVIGVQSEITPSAYLSLKQGKIITVENTD
TIADGIAVKKIGDLTFDIMRNTLDDVVLVSDQEIVNAILILAESAKVIAEGAGAAAVAALLSGKINVKGNVVAVVSGGNI
DVTMLAKVLYKGLVQTGRLIMLKGLIPDRPGMLAQVTGVLGRLGVNIVEIRHERYNPLIRPNYTEVDVIVETPPEEGAVD
RVIEELSRLGFNFKVEVP

Sequences:

>Translated_418_residues
MLSGELYITRVNEVYELSREALTLIKDAQAKGIIHRTPLYRSDTLSSLTNADVYLKLEALQKTGSFKVRGAYNAVTHYIN
DDVKHVVTASAGNHAQGVAYVAKIYGLKSTIVMPKYTPWIKISNTRKYGAEVILEGQSYYEAEKYAIELTKELKAKMIHA
YDDPFVIAGQGTIGWEIIEDLKNIDYVIVPVGGGGLISGIASVIKTISPNTRVIGVQSEITPSAYLSLKQGKIITVENTD
TIADGIAVKKIGDLTFDIMRNTLDDVVLVSDQEIVNAILILAESAKVIAEGAGAAAVAALLSGKINVKGNVVAVVSGGNI
DVTMLAKVLYKGLVQTGRLIMLKGLIPDRPGMLAQVTGVLGRLGVNIVEIRHERYNPLIRPNYTEVDVIVETPPEEGAVD
RVIEELSRLGFNFKVEVP
>Mature_418_residues
MLSGELYITRVNEVYELSREALTLIKDAQAKGIIHRTPLYRSDTLSSLTNADVYLKLEALQKTGSFKVRGAYNAVTHYIN
DDVKHVVTASAGNHAQGVAYVAKIYGLKSTIVMPKYTPWIKISNTRKYGAEVILEGQSYYEAEKYAIELTKELKAKMIHA
YDDPFVIAGQGTIGWEIIEDLKNIDYVIVPVGGGGLISGIASVIKTISPNTRVIGVQSEITPSAYLSLKQGKIITVENTD
TIADGIAVKKIGDLTFDIMRNTLDDVVLVSDQEIVNAILILAESAKVIAEGAGAAAVAALLSGKINVKGNVVAVVSGGNI
DVTMLAKVLYKGLVQTGRLIMLKGLIPDRPGMLAQVTGVLGRLGVNIVEIRHERYNPLIRPNYTEVDVIVETPPEEGAVD
RVIEELSRLGFNFKVEVP

Specific function: Acts on both serine and threonine, and properly considered as a hydroxy amino acid deaminase [H]

COG id: COG1171

COG function: function code E; Threonine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine/threonine dehydratase family [H]

Homologues:

Organism=Homo sapiens, GI11345492, Length=299, Percent_Identity=37.4581939799331, Blast_Score=192, Evalue=5e-49,
Organism=Homo sapiens, GI33469958, Length=321, Percent_Identity=29.595015576324, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI19923959, Length=301, Percent_Identity=27.5747508305648, Blast_Score=92, Evalue=1e-18,
Organism=Escherichia coli, GI1789505, Length=301, Percent_Identity=45.8471760797342, Blast_Score=212, Evalue=4e-56,
Organism=Escherichia coli, GI1790207, Length=340, Percent_Identity=36.1764705882353, Blast_Score=186, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI71991565, Length=366, Percent_Identity=40.9836065573771, Blast_Score=239, Evalue=2e-63,
Organism=Caenorhabditis elegans, GI17537387, Length=346, Percent_Identity=40.7514450867052, Blast_Score=202, Evalue=3e-52,
Organism=Caenorhabditis elegans, GI17508781, Length=293, Percent_Identity=31.740614334471, Blast_Score=140, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6320930, Length=397, Percent_Identity=33.7531486146096, Blast_Score=186, Evalue=5e-48,
Organism=Saccharomyces cerevisiae, GI6322631, Length=301, Percent_Identity=37.2093023255814, Blast_Score=186, Evalue=7e-48,
Organism=Saccharomyces cerevisiae, GI6319788, Length=286, Percent_Identity=26.5734265734266, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21355833, Length=366, Percent_Identity=41.2568306010929, Blast_Score=203, Evalue=2e-52,
Organism=Drosophila melanogaster, GI24645328, Length=283, Percent_Identity=41.696113074205, Blast_Score=154, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR005789 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.3.1.19 [H]

Molecular weight: Translated: 45335; Mature: 45335

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSGELYITRVNEVYELSREALTLIKDAQAKGIIHRTPLYRSDTLSSLTNADVYLKLEAL
CCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHCCCEEEEEEEEH
QKTGSFKVRGAYNAVTHYINDDVKHVVTASAGNHAQGVAYVAKIYGLKSTIVMPKYTPWI
HCCCCEEEEEHHHHHHHHHCCCHHEEEEECCCCCCHHHHHHHHHHCCCEEEECCCCCCEE
KISNTRKYGAEVILEGQSYYEAEKYAIELTKELKAKMIHAYDDPFVIAGQGTIGWEIIED
EEECCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEECCCCHHHHHHH
LKNIDYVIVPVGGGGLISGIASVIKTISPNTRVIGVQSEITPSAYLSLKQGKIITVENTD
HHCCCEEEEEECCCHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHEEECCCEEEEEECCC
TIADGIAVKKIGDLTFDIMRNTLDDVVLVSDQEIVNAILILAESAKVIAEGAGAAAVAAL
HHHCCEEEHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHCCCCCEECCCCCHHHHHHH
LSGKINVKGNVVAVVSGGNIDVTMLAKVLYKGLVQTGRLIMLKGLIPDRPGMLAQVTGVL
HCCCEEECCCEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHH
GRLGVNIVEIRHERYNPLIRPNYTEVDVIVETPPEEGAVDRVIEELSRLGFNFKVEVP
HHHCCEEEEEEHHHCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCEEEECC
>Mature Secondary Structure
MLSGELYITRVNEVYELSREALTLIKDAQAKGIIHRTPLYRSDTLSSLTNADVYLKLEAL
CCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHCCCEEEEEEEEH
QKTGSFKVRGAYNAVTHYINDDVKHVVTASAGNHAQGVAYVAKIYGLKSTIVMPKYTPWI
HCCCCEEEEEHHHHHHHHHCCCHHEEEEECCCCCCHHHHHHHHHHCCCEEEECCCCCCEE
KISNTRKYGAEVILEGQSYYEAEKYAIELTKELKAKMIHAYDDPFVIAGQGTIGWEIIED
EEECCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEECCCCHHHHHHH
LKNIDYVIVPVGGGGLISGIASVIKTISPNTRVIGVQSEITPSAYLSLKQGKIITVENTD
HHCCCEEEEEECCCHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHEEECCCEEEEEECCC
TIADGIAVKKIGDLTFDIMRNTLDDVVLVSDQEIVNAILILAESAKVIAEGAGAAAVAAL
HHHCCEEEHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHCCCCCEECCCCCHHHHHHH
LSGKINVKGNVVAVVSGGNIDVTMLAKVLYKGLVQTGRLIMLKGLIPDRPGMLAQVTGVL
HCCCEEECCCEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHH
GRLGVNIVEIRHERYNPLIRPNYTEVDVIVETPPEEGAVDRVIEELSRLGFNFKVEVP
HHHCCEEEEEEHHHCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA