Click here to switch to the map view.

The map label for this gene is adh [H]

Identifier: 159041485

GI number: 159041485

Start: 957462

End: 958511

Strand: Reverse

Name: adh [H]

Synonym: Cmaq_0914

Alternate gene names: 159041485

Gene position: 958511-957462 (Counterclockwise)

Preceding gene: 159041486

Following gene: 159041478

Centisome position: 46.14

GC content: 47.14

Gene sequence:

>1050_bases
ATGCCTGATTTTATGCGTGCAATGAGGCTTGTGGAGTTTGGTAAGCCTCTTAAACTCCAGGAGGTTCCAATACCTAAACC
TAAGGGTACTGAGGTTTTAATTAAGGTTGAGGGTGCTGGTGTATGCCATAGTGTTGTTCACTTCGTGGATGGTAGGTTTG
GTAGGATTGATGTGAAGGCCCTTGGTTTAAGAATACCAGTAACCCCTGGTCATGAGATAGCCGGTACTGTGGCTGCTGTT
GGGGATGATGTGGAGGGGGTTAAGGAGGGGGATAGGGTTGCTGTTGACCCATGGATAGGTGATGGAACCTGCCACTACTG
TAAACTGGGTGAGGAGCAGTTGTGCGAGCACCCGATTAAGATTGGTGAGAACATTGATGGTGGCTTCGCTGAGTACGTGC
TAATACCGCACTATAGGTACCTTTACGTGTTAAGGAACCTTGACACCGTTAACGCATCCCCATTACCCTGCGCTGGCTTA
ACACCCTATAGGGCCCTGGTTAGGAAGGCTCAGGTTAAGCCGTCTGAGTATGTTGCAGTAATAGGTGCTGGTGGTGGGTT
GGGAACCATGGCTATTCAGATAGCTAAGGTAATGGGGGCTATAGTCATTGGTATTGATGTTAGGGATGAGGCGCTTAAGG
AGATTGAGCGAGCTGGGGCTGATTACGTAATTAACGGTAGGGGTAATGTTGTTGAAGAGGTTAGGAAAATTACAGGCGGT
AGGGGGGTTAATGTCATTGTTGATACAGTGGGTTCTAATGAAACCTTAGGCACGTATATTGATGCATTAGATAAACTGGG
CAGGTACATTATCCTAGGCCTATATGGTGGTGACTTAACTTACCACGCACCCTATATTACGCAAAGGGAGATTCAAATAA
TGGGTAGTTTAACAGGTAACCTAAGTGACTTCATGAGTGTCATGAGGCTTGCTGACAGTGGTAAGATAAGGCCCCTTGTT
ACTAAGGTAATGAGGCTTGAGGAGGCTAATGAGGCACTTGACAACCTCAGGTATGCGAGGGTAACCGCTAGGCAGGTTTT
AGTGCCTTAG

Upstream 100 bases:

>100_bases
GATTCATAGCCTTTTACGTTATCCAGCATTAAGATTATGTTTAAACATATTGATACTAGTTAGTAATTAATGCTTTTAAA
TGTAATACCCTATTACTAGT

Downstream 100 bases:

>100_bases
ATCATTACCTTAAGTCCACGTAGCATTAAATATAATCCTATTATCAACAGTATAACACCCACCATGGGCATTATCCCAAC
CACAATACTGATTGTTATTA

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MPDFMRAMRLVEFGKPLKLQEVPIPKPKGTEVLIKVEGAGVCHSVVHFVDGRFGRIDVKALGLRIPVTPGHEIAGTVAAV
GDDVEGVKEGDRVAVDPWIGDGTCHYCKLGEEQLCEHPIKIGENIDGGFAEYVLIPHYRYLYVLRNLDTVNASPLPCAGL
TPYRALVRKAQVKPSEYVAVIGAGGGLGTMAIQIAKVMGAIVIGIDVRDEALKEIERAGADYVINGRGNVVEEVRKITGG
RGVNVIVDTVGSNETLGTYIDALDKLGRYIILGLYGGDLTYHAPYITQREIQIMGSLTGNLSDFMSVMRLADSGKIRPLV
TKVMRLEEANEALDNLRYARVTARQVLVP

Sequences:

>Translated_349_residues
MPDFMRAMRLVEFGKPLKLQEVPIPKPKGTEVLIKVEGAGVCHSVVHFVDGRFGRIDVKALGLRIPVTPGHEIAGTVAAV
GDDVEGVKEGDRVAVDPWIGDGTCHYCKLGEEQLCEHPIKIGENIDGGFAEYVLIPHYRYLYVLRNLDTVNASPLPCAGL
TPYRALVRKAQVKPSEYVAVIGAGGGLGTMAIQIAKVMGAIVIGIDVRDEALKEIERAGADYVINGRGNVVEEVRKITGG
RGVNVIVDTVGSNETLGTYIDALDKLGRYIILGLYGGDLTYHAPYITQREIQIMGSLTGNLSDFMSVMRLADSGKIRPLV
TKVMRLEEANEALDNLRYARVTARQVLVP
>Mature_348_residues
PDFMRAMRLVEFGKPLKLQEVPIPKPKGTEVLIKVEGAGVCHSVVHFVDGRFGRIDVKALGLRIPVTPGHEIAGTVAAVG
DDVEGVKEGDRVAVDPWIGDGTCHYCKLGEEQLCEHPIKIGENIDGGFAEYVLIPHYRYLYVLRNLDTVNASPLPCAGLT
PYRALVRKAQVKPSEYVAVIGAGGGLGTMAIQIAKVMGAIVIGIDVRDEALKEIERAGADYVINGRGNVVEEVRKITGGR
GVNVIVDTVGSNETLGTYIDALDKLGRYIILGLYGGDLTYHAPYITQREIQIMGSLTGNLSDFMSVMRLADSGKIRPLVT
KVMRLEEANEALDNLRYARVTARQVLVP

Specific function: Preferred Specificity Is Towards 1-Propanol. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=356, Percent_Identity=29.2134831460674, Blast_Score=125, Evalue=4e-29,
Organism=Homo sapiens, GI13236495, Length=356, Percent_Identity=29.2134831460674, Blast_Score=125, Evalue=4e-29,
Organism=Homo sapiens, GI194239676, Length=244, Percent_Identity=33.1967213114754, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI156627571, Length=330, Percent_Identity=29.0909090909091, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI4501933, Length=375, Percent_Identity=27.4666666666667, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI34577061, Length=387, Percent_Identity=26.8733850129199, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI71565154, Length=287, Percent_Identity=28.2229965156794, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI22538446, Length=286, Percent_Identity=27.972027972028, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI22538444, Length=286, Percent_Identity=27.972027972028, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI71743840, Length=377, Percent_Identity=24.9336870026525, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI262073058, Length=376, Percent_Identity=25, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI87081918, Length=324, Percent_Identity=32.4074074074074, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1788073, Length=327, Percent_Identity=29.9694189602446, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI226510992, Length=320, Percent_Identity=28.4375, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1788075, Length=352, Percent_Identity=27.2727272727273, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1787863, Length=354, Percent_Identity=26.8361581920904, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI1790045, Length=340, Percent_Identity=25.2941176470588, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1786518, Length=351, Percent_Identity=29.6296296296296, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI87082401, Length=340, Percent_Identity=26.1764705882353, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI87082125, Length=335, Percent_Identity=28.6567164179104, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1788407, Length=349, Percent_Identity=25.7879656160458, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1790485, Length=276, Percent_Identity=29.3478260869565, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1786552, Length=371, Percent_Identity=26.4150943396226, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790718, Length=296, Percent_Identity=23.3108108108108, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1786825, Length=282, Percent_Identity=24.113475177305, Blast_Score=61, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI71988145, Length=351, Percent_Identity=30.4843304843305, Blast_Score=155, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI17562584, Length=353, Percent_Identity=28.8951841359773, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17562582, Length=352, Percent_Identity=28.4090909090909, Blast_Score=127, Evalue=9e-30,
Organism=Caenorhabditis elegans, GI17562876, Length=334, Percent_Identity=28.4431137724551, Blast_Score=104, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI17562878, Length=251, Percent_Identity=30.6772908366534, Blast_Score=97, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17544682, Length=377, Percent_Identity=25.1989389920424, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI25146526, Length=370, Percent_Identity=26.2162162162162, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17507255, Length=350, Percent_Identity=25.7142857142857, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71997431, Length=372, Percent_Identity=26.0752688172043, Blast_Score=71, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6323961, Length=356, Percent_Identity=29.4943820224719, Blast_Score=149, Evalue=9e-37,
Organism=Saccharomyces cerevisiae, GI6323729, Length=352, Percent_Identity=27.8409090909091, Blast_Score=145, Evalue=8e-36,
Organism=Saccharomyces cerevisiae, GI6324486, Length=353, Percent_Identity=29.1784702549575, Blast_Score=145, Evalue=8e-36,
Organism=Saccharomyces cerevisiae, GI6319621, Length=354, Percent_Identity=29.0960451977401, Blast_Score=139, Evalue=5e-34,
Organism=Saccharomyces cerevisiae, GI6320033, Length=365, Percent_Identity=26.8493150684932, Blast_Score=96, Evalue=6e-21,
Organism=Saccharomyces cerevisiae, GI6319955, Length=334, Percent_Identity=26.0479041916168, Blast_Score=95, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6322619, Length=334, Percent_Identity=26.0479041916168, Blast_Score=95, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6323099, Length=339, Percent_Identity=25.6637168141593, Blast_Score=87, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6319258, Length=362, Percent_Identity=27.6243093922652, Blast_Score=77, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6319520, Length=260, Percent_Identity=27.6923076923077, Blast_Score=76, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6319257, Length=359, Percent_Identity=27.5766016713092, Blast_Score=76, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6323980, Length=210, Percent_Identity=31.9047619047619, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6319949, Length=345, Percent_Identity=25.7971014492754, Blast_Score=70, Evalue=7e-13,
Organism=Drosophila melanogaster, GI17137530, Length=338, Percent_Identity=27.810650887574, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI17737897, Length=346, Percent_Identity=28.3236994219653, Blast_Score=79, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 37862; Mature: 37730

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDFMRAMRLVEFGKPLKLQEVPIPKPKGTEVLIKVEGAGVCHSVVHFVDGRFGRIDVKA
CCHHHHHHHHHHCCCCCEEECCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCEEEEEE
LGLRIPVTPGHEIAGTVAAVGDDVEGVKEGDRVAVDPWIGDGTCHYCKLGEEQLCEHPIK
EEEEECCCCCCHHHHHHHHCCCCCHHHCCCCEEEECCCCCCCCEEEEECCHHHHHHCHHH
IGENIDGGFAEYVLIPHYRYLYVLRNLDTVNASPLPCAGLTPYRALVRKAQVKPSEYVAV
CCCCCCCCCEEEEEECCCEEEHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEE
IGAGGGLGTMAIQIAKVMGAIVIGIDVRDEALKEIERAGADYVINGRGNVVEEVRKITGG
EECCCCHHHHHHHHHHHHCEEEEEEECCHHHHHHHHHCCCCEEECCCCHHHHHHHHHHCC
RGVNVIVDTVGSNETLGTYIDALDKLGRYIILGLYGGDLTYHAPYITQREIQIMGSLTGN
CCCEEEEECCCCCCHHHHHHHHHHHCCCEEEEEEECCCEEEECCCCCHHHEEEEEHHCCC
LSDFMSVMRLADSGKIRPLVTKVMRLEEANEALDNLRYARVTARQVLVP
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PDFMRAMRLVEFGKPLKLQEVPIPKPKGTEVLIKVEGAGVCHSVVHFVDGRFGRIDVKA
CHHHHHHHHHHCCCCCEEECCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCEEEEEE
LGLRIPVTPGHEIAGTVAAVGDDVEGVKEGDRVAVDPWIGDGTCHYCKLGEEQLCEHPIK
EEEEECCCCCCHHHHHHHHCCCCCHHHCCCCEEEECCCCCCCCEEEEECCHHHHHHCHHH
IGENIDGGFAEYVLIPHYRYLYVLRNLDTVNASPLPCAGLTPYRALVRKAQVKPSEYVAV
CCCCCCCCCEEEEEECCCEEEHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEE
IGAGGGLGTMAIQIAKVMGAIVIGIDVRDEALKEIERAGADYVINGRGNVVEEVRKITGG
EECCCCHHHHHHHHHHHHCEEEEEEECCHHHHHHHHHCCCCEEECCCCHHHHHHHHHHCC
RGVNVIVDTVGSNETLGTYIDALDKLGRYIILGLYGGDLTYHAPYITQREIQIMGSLTGN
CCCEEEEECCCCCCHHHHHHHHHHHCCCEEEEEEECCCEEEECCCCCHHHEEEEEHHCCC
LSDFMSVMRLADSGKIRPLVTKVMRLEEANEALDNLRYARVTARQVLVP
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572479 [H]