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The map label for this gene is pfpI [H]

Identifier: 159041453

GI number: 159041453

Start: 925002

End: 925577

Strand: Reverse

Name: pfpI [H]

Synonym: Cmaq_0881

Alternate gene names: 159041453

Gene position: 925577-925002 (Counterclockwise)

Preceding gene: 159041457

Following gene: 159041452

Centisome position: 44.55

GC content: 47.22

Gene sequence:

>576_bases
ATGGCTAAGGCTAGGATTCTAATAATAGCTGGAGATGCCGTTGAAGCTCTTGAACTCTTCTACCCATACTATAGGCTTAA
GGAGGAGGGGTGGGATGTTGACGTGGCGGCTCCAAGTAGGAAGGATTTAAGGACTGTGGTTCATGATTTTGAACCAGGGT
GGGAAACTTACAGTGAGAAACCTGGTTACCTCTTTAAGTGGGTTACTAAAACACTCTCCGAGGTTAAGCCTGAGGAGTAC
GATGGGTTAGTTATACCAGGGGGTAGAATGCCTGAGTACGTTAGGGTTGTTGCCTCAGAGGATGTTAAGCGCATTGTAAG
GCACTTCTTTGAGACTAAGAAACCTGTGGCAGCAATATGCCATGCACCTCAAATACTGGCTGCAGCCGGCGTGGTTAAGG
GTAGAAGAATGACTAGCTACATAGCCGTAAGACCCGAGGTTGAGAATAATGGAGGAATATGGGTTGATGAGGAGGTTGTG
GTAGATGGGAACCTAGTCACGTCTAGGGCATGGCCTGATAACCCAGCTTGGATGAGGGAATTCATAAAGCTAGTAAAGGC
TAGGATAGGTGGTTAG

Upstream 100 bases:

>100_bases
CATATAGTTAGGAAAAATATCCTACTTATAAAGATTACCCATCATACCAAACCCACATATCTGCATAAAGCTTAAATATT
CTCAAAAATTATTATTAATC

Downstream 100 bases:

>100_bases
TTAGGTAATTTACTTAAAGACCATTAAACACCTTAATCTTAAATTATTTCAATATGCTCTTAAGGTCATTAGGTTCCTGG
TATAATTCACTGTTTAGTAT

Product: PfpI family intracellular peptidase

Products: NA

Alternate protein names: Intracellular protease I [H]

Number of amino acids: Translated: 191; Mature: 190

Protein sequence:

>191_residues
MAKARILIIAGDAVEALELFYPYYRLKEEGWDVDVAAPSRKDLRTVVHDFEPGWETYSEKPGYLFKWVTKTLSEVKPEEY
DGLVIPGGRMPEYVRVVASEDVKRIVRHFFETKKPVAAICHAPQILAAAGVVKGRRMTSYIAVRPEVENNGGIWVDEEVV
VDGNLVTSRAWPDNPAWMREFIKLVKARIGG

Sequences:

>Translated_191_residues
MAKARILIIAGDAVEALELFYPYYRLKEEGWDVDVAAPSRKDLRTVVHDFEPGWETYSEKPGYLFKWVTKTLSEVKPEEY
DGLVIPGGRMPEYVRVVASEDVKRIVRHFFETKKPVAAICHAPQILAAAGVVKGRRMTSYIAVRPEVENNGGIWVDEEVV
VDGNLVTSRAWPDNPAWMREFIKLVKARIGG
>Mature_190_residues
AKARILIIAGDAVEALELFYPYYRLKEEGWDVDVAAPSRKDLRTVVHDFEPGWETYSEKPGYLFKWVTKTLSEVKPEEYD
GLVIPGGRMPEYVRVVASEDVKRIVRHFFETKKPVAAICHAPQILAAAGVVKGRRMTSYIAVRPEVENNGGIWVDEEVVV
DGNLVTSRAWPDNPAWMREFIKLVKARIGG

Specific function: Highly stable protease. Although the physiological function is unclear it is the dominant protease in P.furiosus [H]

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PfpI endopeptidase domain [H]

Homologues:

Organism=Escherichia coli, GI87082219, Length=166, Percent_Identity=36.144578313253, Blast_Score=102, Evalue=2e-23,
Organism=Drosophila melanogaster, GI28571932, Length=181, Percent_Identity=29.8342541436464, Blast_Score=68, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006286
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 21618; Mature: 21487

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKARILIIAGDAVEALELFYPYYRLKEEGWDVDVAAPSRKDLRTVVHDFEPGWETYSEK
CCCEEEEEEECCHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHCCCCCCCCCCC
PGYLFKWVTKTLSEVKPEEYDGLVIPGGRMPEYVRVVASEDVKRIVRHFFETKKPVAAIC
CCHHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
HAPQILAAAGVVKGRRMTSYIAVRPEVENNGGIWVDEEVVVDGNLVTSRAWPDNPAWMRE
CCHHHHHHHHHHCCCCEEEEEEEECCCCCCCCEEECCEEEECCCEEECCCCCCCHHHHHH
FIKLVKARIGG
HHHHHHHHHCC
>Mature Secondary Structure 
AKARILIIAGDAVEALELFYPYYRLKEEGWDVDVAAPSRKDLRTVVHDFEPGWETYSEK
CCEEEEEEECCHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHCCCCCCCCCCC
PGYLFKWVTKTLSEVKPEEYDGLVIPGGRMPEYVRVVASEDVKRIVRHFFETKKPVAAIC
CCHHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
HAPQILAAAGVVKGRRMTSYIAVRPEVENNGGIWVDEEVVVDGNLVTSRAWPDNPAWMRE
CCHHHHHHHHHHCCCCEEEEEEEECCCCCCCCEEECCEEEECCCEEECCCCCCCHHHHHH
FIKLVKARIGG
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8626329 [H]