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The map label for this gene is glmS [H]

Identifier: 159041405

GI number: 159041405

Start: 874870

End: 875931

Strand: Reverse

Name: glmS [H]

Synonym: Cmaq_0832

Alternate gene names: 159041405

Gene position: 875931-874870 (Counterclockwise)

Preceding gene: 159041409

Following gene: 159041403

Centisome position: 42.16

GC content: 39.83

Gene sequence:

>1062_bases
ATGTCAAGCATGATCCAGGATATCTTGGAGATCCCTAGATCACTGGATTCGCTTTCATTAATGATTAATGATATTAGGAA
ATTAGGTTCATTGCATAGGGGACTGGGGAAGGTTTTTCTAGTTGGTGCTGGTTCATCATACTACGCCTCAATGTATGCTG
CATCCCATGCTTTAAGTAGTGGGTTAAGTAAATGCATTTACGCAATCCCATCATCAGAATTCATATACAACTACTCTAAG
ATGATTGATTCATCAAGCCTAGTAATTGCAGTATCCCGCTCCGGGGAGACCGCTGAAACCCTTGAGGCCTTGAGGATTGC
TAAGAGTAATGGTGCTAGGACAATAATGCTAAGTATTAGTGATAGTGGACGCAATGTAGGGTATATTGATAACTATGTCT
TCGTAAATATTGGTCAAGAGAGGAGCATAGTCATGACTAAGAGCTTCATTACGCTCTCAGCTGCTGCGGCAATTCTCTTA
AAAATCATTACAGGTATTGAACAGGACTTTACAAGTATTATTAAGGTTTTATCAACATGCATGGGGAATATTATTAAAGA
CCGTGATTTAAACAATAGATTAACTGGAATTACTGAGGATTGGATTAATAATGGTATTAGTAGATTCATATTCCTTGGTC
ATGGGTCATCATACCCCATAGCCCTTGAAGCAGCCTTAAAGTTTGAGGAGACATCATATGTTGCTGTTCAGGCATTAAAC
ACCCTTGAGATTAGGCATGGACCAATAGCCACTATTGGCGAGAGGCAGGCTGTAGTTATGCTTAATCAATCAGGAGTAAT
GAGCACGGCTGCAGTTAAGTTGCTTAGTGAATTAAGGGAGAGGAGTAAAGGCACTGAGACTAGGGTAATTATGGTTACTA
CCGATGATAATTTAAGGGACTTAGATGATGCAATACATGTACCATGCAGGACTGGGGCTGAGGAATGGGGTGCCTTAGCG
TTAATTTTACCAATGTATCTGTTGGCTAATCAATATGCCTTGAGGAGAGGTATTAATATTGAAGAACCAAGGAACCTAAC
TAGGGTTGTTAAGAACTTTTAA

Upstream 100 bases:

>100_bases
ATCTTTATTATCGTAGCCTTAGAATAATATGATAACTATATAGTTTTAGTCATAATGTATTTATATTAATACTTATTAAG
TAATCATAATTTGTGTAACT

Downstream 100 bases:

>100_bases
ACATACATTAGTTAAGAACTGATGATACCAATATCTCTTAATCCCCTAAGCCTTAAAGCCGATTTCAACACTCTTCTATA
TCTTACTTAATATAATCCTC

Product: glutamine--fructose-6-phosphate transaminase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 353; Mature: 352

Protein sequence:

>353_residues
MSSMIQDILEIPRSLDSLSLMINDIRKLGSLHRGLGKVFLVGAGSSYYASMYAASHALSSGLSKCIYAIPSSEFIYNYSK
MIDSSSLVIAVSRSGETAETLEALRIAKSNGARTIMLSISDSGRNVGYIDNYVFVNIGQERSIVMTKSFITLSAAAAILL
KIITGIEQDFTSIIKVLSTCMGNIIKDRDLNNRLTGITEDWINNGISRFIFLGHGSSYPIALEAALKFEETSYVAVQALN
TLEIRHGPIATIGERQAVVMLNQSGVMSTAAVKLLSELRERSKGTETRVIMVTTDDNLRDLDDAIHVPCRTGAEEWGALA
LILPMYLLANQYALRRGINIEEPRNLTRVVKNF

Sequences:

>Translated_353_residues
MSSMIQDILEIPRSLDSLSLMINDIRKLGSLHRGLGKVFLVGAGSSYYASMYAASHALSSGLSKCIYAIPSSEFIYNYSK
MIDSSSLVIAVSRSGETAETLEALRIAKSNGARTIMLSISDSGRNVGYIDNYVFVNIGQERSIVMTKSFITLSAAAAILL
KIITGIEQDFTSIIKVLSTCMGNIIKDRDLNNRLTGITEDWINNGISRFIFLGHGSSYPIALEAALKFEETSYVAVQALN
TLEIRHGPIATIGERQAVVMLNQSGVMSTAAVKLLSELRERSKGTETRVIMVTTDDNLRDLDDAIHVPCRTGAEEWGALA
LILPMYLLANQYALRRGINIEEPRNLTRVVKNF
>Mature_352_residues
SSMIQDILEIPRSLDSLSLMINDIRKLGSLHRGLGKVFLVGAGSSYYASMYAASHALSSGLSKCIYAIPSSEFIYNYSKM
IDSSSLVIAVSRSGETAETLEALRIAKSNGARTIMLSISDSGRNVGYIDNYVFVNIGQERSIVMTKSFITLSAAAAILLK
IITGIEQDFTSIIKVLSTCMGNIIKDRDLNNRLTGITEDWINNGISRFIFLGHGSSYPIALEAALKFEETSYVAVQALNT
LEIRHGPIATIGERQAVVMLNQSGVMSTAAVKLLSELRERSKGTETRVIMVTTDDNLRDLDDAIHVPCRTGAEEWGALAL
ILPMYLLANQYALRRGINIEEPRNLTRVVKNF

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI4826742, Length=326, Percent_Identity=24.5398773006135, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI205277386, Length=321, Percent_Identity=24.2990654205607, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI1790167, Length=321, Percent_Identity=29.595015576324, Blast_Score=103, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17539970, Length=323, Percent_Identity=25.3869969040248, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17532899, Length=361, Percent_Identity=22.7146814404432, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17532897, Length=361, Percent_Identity=22.7146814404432, Blast_Score=74, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6322745, Length=334, Percent_Identity=23.9520958083832, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21357745, Length=363, Percent_Identity=23.6914600550964, Blast_Score=90, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 38700; Mature: 38569

Theoretical pI: Translated: 7.54; Mature: 7.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSMIQDILEIPRSLDSLSLMINDIRKLGSLHRGLGKVFLVGAGSSYYASMYAASHALSS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHH
GLSKCIYAIPSSEFIYNYSKMIDSSSLVIAVSRSGETAETLEALRIAKSNGARTIMLSIS
HHHHHHHHCCCCHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCEEEEEEEC
DSGRNVGYIDNYVFVNIGQERSIVMTKSFITLSAAAAILLKIITGIEQDFTSIIKVLSTC
CCCCCCCEECCEEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
MGNIIKDRDLNNRLTGITEDWINNGISRFIFLGHGSSYPIALEAALKFEETSYVAVQALN
HHHHHHCCCCCCCCCCCCHHHHCCCCEEEEEEECCCCCCEEEEEEEEECCCCEEEEEEHH
TLEIRHGPIATIGERQAVVMLNQSGVMSTAAVKLLSELRERSKGTETRVIMVTTDDNLRD
HEEECCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHH
LDDAIHVPCRTGAEEWGALALILPMYLLANQYALRRGINIEEPRNLTRVVKNF
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure 
SSMIQDILEIPRSLDSLSLMINDIRKLGSLHRGLGKVFLVGAGSSYYASMYAASHALSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHH
GLSKCIYAIPSSEFIYNYSKMIDSSSLVIAVSRSGETAETLEALRIAKSNGARTIMLSIS
HHHHHHHHCCCCHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCEEEEEEEC
DSGRNVGYIDNYVFVNIGQERSIVMTKSFITLSAAAAILLKIITGIEQDFTSIIKVLSTC
CCCCCCCEECCEEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
MGNIIKDRDLNNRLTGITEDWINNGISRFIFLGHGSSYPIALEAALKFEETSYVAVQALN
HHHHHHCCCCCCCCCCCCHHHHCCCCEEEEEEECCCCCCEEEEEEEEECCCCEEEEEEHH
TLEIRHGPIATIGERQAVVMLNQSGVMSTAAVKLLSELRERSKGTETRVIMVTTDDNLRD
HEEECCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHH
LDDAIHVPCRTGAEEWGALALILPMYLLANQYALRRGINIEEPRNLTRVVKNF
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA