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The map label for this gene is uppS [H]

Identifier: 159041359

GI number: 159041359

Start: 821694

End: 822401

Strand: Reverse

Name: uppS [H]

Synonym: Cmaq_0786

Alternate gene names: 159041359

Gene position: 822401-821694 (Counterclockwise)

Preceding gene: 159041361

Following gene: 159041356

Centisome position: 39.58

GC content: 41.81

Gene sequence:

>708_bases
ATGGCTAATAATATTAAGCGTTTACCGAATCATATTGGGATCATTCCAGATGGTAATAGAAGGTGGGCTATGGCTCATGG
CATGGATATATATACGGCTTACTTAATCGGGTCGGATAAGGTTGAGGAGGTTTTAGAATGGGCGCTTGATAATAATGTGC
AGGCAGTCACCGTATATATTCTATCCTATGAGAATTTCATGAATAGGAGCGAGATGGAGAAGAGGATTCTATACGAGTTA
CTCATTAGGAAGCTTAAGAAGGCTAGGGAGGATCCTAGGATACATGGTAATAAAGTTAAGGTTACCTTAATAGGTAGGTG
GAGGAACCTACCGCCATACGTCGTTGATGAGGCTATTAAGACCATGAACGCCACCGAGATGTATAATTCCCACTTCCTCA
ACCTAGCGGTGGTTTATGGTGGTTACCAATCCATCGTGGACTTAGTTAATACAGCCATCACTAAGATTGGCAGGTTAATT
AATGATGATGAATTAATTAAACTACTACCAACCAGCTTCCTACCTAACCCATTCATAGACCTAGTTATCAGAACCGGAGG
CGAGAGGAGGCTAAGTAACTTCTTTCCGCTGGAATCCATTTACGCCGAATTATACTTCCTTGATAAATATTGGCCTGACT
TCAGTAGAGAGGACTTCCAAGAGGCCCTAAGGTATTATGCAAGCGTTGAGAGGAAATTCGGTAAATGA

Upstream 100 bases:

>100_bases
TCTCATTTCAATAATATACACATATATGTAAAGATAAATGCATGAACTTCATCGTACAGTAATTTTTATAAATTGAACTG
TCAGATATTGGGCAACAGAT

Downstream 100 bases:

>100_bases
AATTGCTAACTCGGATTAACATAACGGTATATACACTGTCCTCTATAGAATCCCCCAATTAATGATGCATTCTTCATCCT
GGAGATAAGTATAGTGGCTA

Product: undecaprenyl diphosphate synthase

Products: NA

Alternate protein names: UPP synthase; Di-trans,poly-cis-decaprenylcistransferase; Undecaprenyl diphosphate synthase; UDS [H]

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MANNIKRLPNHIGIIPDGNRRWAMAHGMDIYTAYLIGSDKVEEVLEWALDNNVQAVTVYILSYENFMNRSEMEKRILYEL
LIRKLKKAREDPRIHGNKVKVTLIGRWRNLPPYVVDEAIKTMNATEMYNSHFLNLAVVYGGYQSIVDLVNTAITKIGRLI
NDDELIKLLPTSFLPNPFIDLVIRTGGERRLSNFFPLESIYAELYFLDKYWPDFSREDFQEALRYYASVERKFGK

Sequences:

>Translated_235_residues
MANNIKRLPNHIGIIPDGNRRWAMAHGMDIYTAYLIGSDKVEEVLEWALDNNVQAVTVYILSYENFMNRSEMEKRILYEL
LIRKLKKAREDPRIHGNKVKVTLIGRWRNLPPYVVDEAIKTMNATEMYNSHFLNLAVVYGGYQSIVDLVNTAITKIGRLI
NDDELIKLLPTSFLPNPFIDLVIRTGGERRLSNFFPLESIYAELYFLDKYWPDFSREDFQEALRYYASVERKFGK
>Mature_234_residues
ANNIKRLPNHIGIIPDGNRRWAMAHGMDIYTAYLIGSDKVEEVLEWALDNNVQAVTVYILSYENFMNRSEMEKRILYELL
IRKLKKAREDPRIHGNKVKVTLIGRWRNLPPYVVDEAIKTMNATEMYNSHFLNLAVVYGGYQSIVDLVNTAITKIGRLIN
DDELIKLLPTSFLPNPFIDLVIRTGGERRLSNFFPLESIYAELYFLDKYWPDFSREDFQEALRYYASVERKFGK

Specific function: Generates undecaprenyl pyrophosphate (UPP) from isopentenyl pyrophosphate (IPP). UPP is probably the precursor of glycosyl carrier lipids [H]

COG id: COG0020

COG function: function code I; Undecaprenyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI45580742, Length=224, Percent_Identity=32.1428571428571, Blast_Score=98, Evalue=7e-21,
Organism=Homo sapiens, GI45580738, Length=224, Percent_Identity=32.1428571428571, Blast_Score=97, Evalue=9e-21,
Organism=Escherichia coli, GI1786371, Length=228, Percent_Identity=35.5263157894737, Blast_Score=123, Evalue=8e-30,
Organism=Caenorhabditis elegans, GI71993029, Length=227, Percent_Identity=27.7533039647577, Blast_Score=74, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6319474, Length=213, Percent_Identity=29.1079812206573, Blast_Score=80, Evalue=3e-16,
Organism=Drosophila melanogaster, GI18857969, Length=214, Percent_Identity=31.7757009345794, Blast_Score=99, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001441
- InterPro:   IPR018520 [H]

Pfam domain/function: PF01255 Prenyltransf [H]

EC number: =2.5.1.31 [H]

Molecular weight: Translated: 27462; Mature: 27331

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: PS01066 UPP_SYNTHETASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANNIKRLPNHIGIIPDGNRRWAMAHGMDIYTAYLIGSDKVEEVLEWALDNNVQAVTVYI
CCCCHHHHHHHCCCCCCCCCEEEHCCCCEEEHEEEECCHHHHHHHHHHHCCCCEEEEEEE
LSYENFMNRSEMEKRILYELLIRKLKKAREDPRIHGNKVKVTLIGRWRNLPPYVVDEAIK
EEHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCHHHHHHHHH
TMNATEMYNSHFLNLAVVYGGYQSIVDLVNTAITKIGRLINDDELIKLLPTSFLPNPFID
HHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHH
LVIRTGGERRLSNFFPLESIYAELYFLDKYWPDFSREDFQEALRYYASVERKFGK
HEEECCCCHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ANNIKRLPNHIGIIPDGNRRWAMAHGMDIYTAYLIGSDKVEEVLEWALDNNVQAVTVYI
CCCHHHHHHHCCCCCCCCCEEEHCCCCEEEHEEEECCHHHHHHHHHHHCCCCEEEEEEE
LSYENFMNRSEMEKRILYELLIRKLKKAREDPRIHGNKVKVTLIGRWRNLPPYVVDEAIK
EEHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCHHHHHHHHH
TMNATEMYNSHFLNLAVVYGGYQSIVDLVNTAITKIGRLINDDELIKLLPTSFLPNPFID
HHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHH
LVIRTGGERRLSNFFPLESIYAELYFLDKYWPDFSREDFQEALRYYASVERKFGK
HEEECCCCHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014 [H]