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The map label for this gene is pyrF [H]

Identifier: 159041327

GI number: 159041327

Start: 783961

End: 784620

Strand: Reverse

Name: pyrF [H]

Synonym: Cmaq_0753

Alternate gene names: 159041327

Gene position: 784620-783961 (Counterclockwise)

Preceding gene: 159041328

Following gene: 159041324

Centisome position: 37.77

GC content: 40.15

Gene sequence:

>660_bases
ATGAGAATAAGAGACCTAAGAGGCATAAGCAGGGTGGTGCTGGCCCTGGACTTAACGGAACCTAGGAGGTATTGGGATAT
AATGAATGAATTAAGGGGTTTAATTAAAATAGTTAAGATTAGTTGGGTAACGTTACTTACAATAGGCCCTGATGGTTTAC
GTAGATTAATAAGTGATAACAAGGATGTTTACTTCCTCATGGATGCTAAACTAGCTGATGTAGGCTTCATAAACAATATA
ATCGCAGGTAAATTTAAGGAACTGGGTATTAATGGGATTATAGTCCATGGATTCATAGGTAAGGTTAATATGCCTAATGT
AAGCGACCTAGATATACTGGTATTGGTTTCCATGACCAGTGGGGGTGAATTATATGACGCCAACTTTGAGGAGGTAATCA
GTATTATCAAGGAGATTAACGCCGCAGGGGTTATTATTGGCGGGAATAAGCCCAATTTAATAAGGAGAGCTAGATCATAC
TTAGGTAATGAATATGTGATACTTAGCCCAGGCATTGGTGCACAGGGGGTTAAGCCCGGTTGCGCGATAGCTAATGGGGC
TGACTTTGAAATAGTGGGGAGGGCTATATATGAGTCAAGTAACCCTAAGGATTCATTCATTAAAATTGAGGATGAATCTA
GGAAAGCAGAATGCGGTTGA

Upstream 100 bases:

>100_bases
ATTACTTAAGTTGATTGAGGACCTAAGGAACAGCGTTAAGAGGAGGCAGGTGAACCAAGGCAATGATACTAATAAATAAC
CCTCCTACCCTCATTAAGCA

Downstream 100 bases:

>100_bases
ATTCATTGGTTGAAAAATAAAAATGTTTTTACCTTTAACTTAATATTTTAACCAGGATTACTCAATCTTGCCTATTGCCT
TTCTTAACGTCTTACCATTG

Product: orotidine 5'-phosphate decarboxylase

Products: NA

Alternate protein names: OMP decarboxylase; OMPDCase; OMPdecase [H]

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MRIRDLRGISRVVLALDLTEPRRYWDIMNELRGLIKIVKISWVTLLTIGPDGLRRLISDNKDVYFLMDAKLADVGFINNI
IAGKFKELGINGIIVHGFIGKVNMPNVSDLDILVLVSMTSGGELYDANFEEVISIIKEINAAGVIIGGNKPNLIRRARSY
LGNEYVILSPGIGAQGVKPGCAIANGADFEIVGRAIYESSNPKDSFIKIEDESRKAECG

Sequences:

>Translated_219_residues
MRIRDLRGISRVVLALDLTEPRRYWDIMNELRGLIKIVKISWVTLLTIGPDGLRRLISDNKDVYFLMDAKLADVGFINNI
IAGKFKELGINGIIVHGFIGKVNMPNVSDLDILVLVSMTSGGELYDANFEEVISIIKEINAAGVIIGGNKPNLIRRARSY
LGNEYVILSPGIGAQGVKPGCAIANGADFEIVGRAIYESSNPKDSFIKIEDESRKAECG
>Mature_219_residues
MRIRDLRGISRVVLALDLTEPRRYWDIMNELRGLIKIVKISWVTLLTIGPDGLRRLISDNKDVYFLMDAKLADVGFINNI
IAGKFKELGINGIIVHGFIGKVNMPNVSDLDILVLVSMTSGGELYDANFEEVISIIKEINAAGVIIGGNKPNLIRRARSY
LGNEYVILSPGIGAQGVKPGCAIANGADFEIVGRAIYESSNPKDSFIKIEDESRKAECG

Specific function: Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) [H]

COG id: COG0284

COG function: function code F; Orotidine-5'-phosphate decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OMP decarboxylase family. Type 1 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR014732
- InterPro:   IPR018089
- InterPro:   IPR001754
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00215 OMPdecase [H]

EC number: =4.1.1.23 [H]

Molecular weight: Translated: 24035; Mature: 24035

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIRDLRGISRVVLALDLTEPRRYWDIMNELRGLIKIVKISWVTLLTIGPDGLRRLISDN
CCCHHHHHHEEEEEEEECCCCHHHHHHHHHHHHHHHHHHEEEEEEEEECHHHHHHHHCCC
KDVYFLMDAKLADVGFINNIIAGKFKELGINGIIVHGFIGKVNMPNVSDLDILVLVSMTS
CCEEEEEECCCCCHHHHHHHHHCCHHHCCCCEEEEEEEECCCCCCCCCCCEEEEEEEECC
GGELYDANFEEVISIIKEINAAGVIIGGNKPNLIRRARSYLGNEYVILSPGIGAQGVKPG
CCEEEECCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCC
CAIANGADFEIVGRAIYESSNPKDSFIKIEDESRKAECG
CEECCCCCHHEEHHHHHCCCCCCCCEEEEECCCCCCCCC
>Mature Secondary Structure
MRIRDLRGISRVVLALDLTEPRRYWDIMNELRGLIKIVKISWVTLLTIGPDGLRRLISDN
CCCHHHHHHEEEEEEEECCCCHHHHHHHHHHHHHHHHHHEEEEEEEEECHHHHHHHHCCC
KDVYFLMDAKLADVGFINNIIAGKFKELGINGIIVHGFIGKVNMPNVSDLDILVLVSMTS
CCEEEEEECCCCCHHHHHHHHHCCHHHCCCCEEEEEEEECCCCCCCCCCCEEEEEEEECC
GGELYDANFEEVISIIKEINAAGVIIGGNKPNLIRRARSYLGNEYVILSPGIGAQGVKPG
CCEEEECCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCC
CAIANGADFEIVGRAIYESSNPKDSFIKIEDESRKAECG
CEECCCCCHHEEHHHHHCCCCCCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]