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The map label for this gene is purL

Identifier: 159041246

GI number: 159041246

Start: 703851

End: 706025

Strand: Reverse

Name: purL

Synonym: Cmaq_0668

Alternate gene names: 159041246

Gene position: 706025-703851 (Counterclockwise)

Preceding gene: 159041249

Following gene: 159041245

Centisome position: 33.98

GC content: 45.66

Gene sequence:

>2175_bases
ATGGGGTTAACAAGCGATGAGGCCAAGATTATAATTAACACCCTAGGTAGGAATCCAACTGAGGCTGAGTGGTTGATCTT
TGAGGCCGAGTGGAGTGAACACTGCTCTTATAAGAGCAGTAGGGCATGGATTAGGTTATTACCATCAAAGTCACCGCTGG
TGATTAGGGGATCTGGTCTTGATGCGCCGATTATTAGAATTAATAATATTGCCGTTACCTTTAAGATAGAGAGCCATAAT
CACCCATCCGCGGTTGACCCATATGATGGGGCAGCCACTGGTGTTGGTGGGATTGTTAGGGATATTTTAACCACGGGCCT
AAGGCCAATAGCCCTCCTTGATAATCTACATTTAGGTAGCTTAGATAATCAGCGTTCCCTATGGTTGAGTAGGAATATCA
TTAAGGGCATATCCGACTACGGTAATAGGATTGGGGTACCAGTGGTTGGTGGGGAGACTTGGTTTGATGAATCCTTCAAC
AATAATCCAATAGTTCTAGTAACCTGCATAGGTGCTGGTGATTTTAAGAGGGTAATATGGGGTGAGGGTAAGGTAGGTGA
CCTAGTCCTAGTTGTGGGTAATGACACCGGTAGGGATGGCATGCTGGGGAGCTCCTTTGCATCAAGGGAACTAAGCAGTA
GCGATGACATAGGCGCGGTGCAGGTAGGTAACCCACTTCTTGAGAAGCTACTCATAGATGCATTAATGGAGCTGGGGGAG
AGGGGGCTAGTTAAGGCAATTAAGGATGTGGGGGGAGGTGGGTTAGCAACGGCTTTAAGTGAATTGGCTCATCAATTAGG
CTTAGGCATTGAGGTTGATTTAACCAACATTAGGCTTAGGGATGAGTTAAAGCCTGAGGAGATACTTGTCTCAGAGTCCC
AGGAGAGGATGATTATTGTTGTTGACCCAAGTAGATTAAGCTATGTTGAAGCAGTGTTAAGGAAGTATGAGGTGGGGTTT
GACCTAATAGGTAAGTTAACTAATGACGGTAAATTCACCGCCTACTACAAGGGGATTAAGTTAATTGACCTACCCCTAGA
CCTAATCACTAATCCCCCTGAACCAATACGCAAATATACTGAACCAGTGTACTTAATGAGGCTAAGGCGTATTCCACCAC
TACCTAGCGTCAAGTTTAATGAGGCTTTAATTAAAGTAGCCTCAAGCCCCAACCTGGCATCTAAGGAGGTAATATACACT
CAGTATGATTACGAAGTCGGTGTTAGGACTGTTATTAAGCCTGGTAGGGCTGGGGCAACGGTACTTAGGTTACTTGAGGA
GGATGGTGGGGACGGTAAGTTAGGGATCGCCGTTAAGGCTGACTCAAACCCAAGGTACAGTTACTTAAATCCATTCACTG
GTGCAGCTAATTCACTGGCTAAGGCGTATAGGAATGTTGCCTCAGTGGGGGCTAAGCCAATAGCTGCCGTTGATTCAATA
AACGTGGGTAATCCTGAGAAGCCGGATAAATACTGGTACTTCGTTAAGACCGTGGAGGGCTTAACATGGATGGGTAATGC
CCTAGGCATACCCTTCGTTGGGGGTAAGGTAAGCTTCTATAATGAGGACTCAGTAACTGGTGCATCAATAAAGCCCGTGG
TGGCAGTGGCAGTGTTGGGTGTGGTTAATGATTACGCTAAGGCAATTGAAGGTGGCTTAACCGGTGAAGGCTGGTTGGTG
ATTATTGGTGACACAGGACCTGAATTAGGGGGCTCTGAATTCCTACACAGTGTACATGGCCTAGTGGCTGGTGAACCCCC
TGAACCTAAGCCATTGAGTGAGGTTAAGAACGCTAACCTAGTTATGCAGTTGATTAATAATGGATTAGCCAAGGCAGTAA
TGGATGTTGGAGTTGGTGGATTAGCTGCAGCACTCATTAAAATGTCCATAATTGGTGGCGTAGGCTTCACAGTGGATCTT
TCTAAAGCCCCATTAACCCAGGGATTAAATGACCCAGTAACCGTGGCCTTCTCCGAAACGAACGCAAGATACATTATTGA
AACCAGTAATCTAAAGGAGACGGTAAGAATCATTGAGGCTAATGGTGTACCTTACGGTGTATTAGGTGAATCAGGGGGAG
GGATAGTGCAGTTTAAGTGGGGTGGCTTGGAGTTAGCATCCCTGAGTGTTGATGACTTAGTTAGTATTAATGATTCCTTG
AGGGGTGTCATATAA

Upstream 100 bases:

>100_bases
GGATTCATAACCAGTATTTCAACAAAAGATTTAAAAAGTTAACCGAGAAATAGTTAGTAACCCATATGTATTCAATTAAA
AAATTAAATGAGGTGATGAA

Downstream 100 bases:

>100_bases
TGTGCGGCATATGGGCTTACCTAGGTCAAGGAGCAAACCTAATGGTGAGCAAAATGGCGCCATGGCTAATGCATAGAGGG
CAGGAGGGATTCTCATACGT

Product: phosphoribosylformylglycinamidine synthase II

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase II; FGAM synthase II

Number of amino acids: Translated: 724; Mature: 723

Protein sequence:

>724_residues
MGLTSDEAKIIINTLGRNPTEAEWLIFEAEWSEHCSYKSSRAWIRLLPSKSPLVIRGSGLDAPIIRINNIAVTFKIESHN
HPSAVDPYDGAATGVGGIVRDILTTGLRPIALLDNLHLGSLDNQRSLWLSRNIIKGISDYGNRIGVPVVGGETWFDESFN
NNPIVLVTCIGAGDFKRVIWGEGKVGDLVLVVGNDTGRDGMLGSSFASRELSSSDDIGAVQVGNPLLEKLLIDALMELGE
RGLVKAIKDVGGGGLATALSELAHQLGLGIEVDLTNIRLRDELKPEEILVSESQERMIIVVDPSRLSYVEAVLRKYEVGF
DLIGKLTNDGKFTAYYKGIKLIDLPLDLITNPPEPIRKYTEPVYLMRLRRIPPLPSVKFNEALIKVASSPNLASKEVIYT
QYDYEVGVRTVIKPGRAGATVLRLLEEDGGDGKLGIAVKADSNPRYSYLNPFTGAANSLAKAYRNVASVGAKPIAAVDSI
NVGNPEKPDKYWYFVKTVEGLTWMGNALGIPFVGGKVSFYNEDSVTGASIKPVVAVAVLGVVNDYAKAIEGGLTGEGWLV
IIGDTGPELGGSEFLHSVHGLVAGEPPEPKPLSEVKNANLVMQLINNGLAKAVMDVGVGGLAAALIKMSIIGGVGFTVDL
SKAPLTQGLNDPVTVAFSETNARYIIETSNLKETVRIIEANGVPYGVLGESGGGIVQFKWGGLELASLSVDDLVSINDSL
RGVI

Sequences:

>Translated_724_residues
MGLTSDEAKIIINTLGRNPTEAEWLIFEAEWSEHCSYKSSRAWIRLLPSKSPLVIRGSGLDAPIIRINNIAVTFKIESHN
HPSAVDPYDGAATGVGGIVRDILTTGLRPIALLDNLHLGSLDNQRSLWLSRNIIKGISDYGNRIGVPVVGGETWFDESFN
NNPIVLVTCIGAGDFKRVIWGEGKVGDLVLVVGNDTGRDGMLGSSFASRELSSSDDIGAVQVGNPLLEKLLIDALMELGE
RGLVKAIKDVGGGGLATALSELAHQLGLGIEVDLTNIRLRDELKPEEILVSESQERMIIVVDPSRLSYVEAVLRKYEVGF
DLIGKLTNDGKFTAYYKGIKLIDLPLDLITNPPEPIRKYTEPVYLMRLRRIPPLPSVKFNEALIKVASSPNLASKEVIYT
QYDYEVGVRTVIKPGRAGATVLRLLEEDGGDGKLGIAVKADSNPRYSYLNPFTGAANSLAKAYRNVASVGAKPIAAVDSI
NVGNPEKPDKYWYFVKTVEGLTWMGNALGIPFVGGKVSFYNEDSVTGASIKPVVAVAVLGVVNDYAKAIEGGLTGEGWLV
IIGDTGPELGGSEFLHSVHGLVAGEPPEPKPLSEVKNANLVMQLINNGLAKAVMDVGVGGLAAALIKMSIIGGVGFTVDL
SKAPLTQGLNDPVTVAFSETNARYIIETSNLKETVRIIEANGVPYGVLGESGGGIVQFKWGGLELASLSVDDLVSINDSL
RGVI
>Mature_723_residues
GLTSDEAKIIINTLGRNPTEAEWLIFEAEWSEHCSYKSSRAWIRLLPSKSPLVIRGSGLDAPIIRINNIAVTFKIESHNH
PSAVDPYDGAATGVGGIVRDILTTGLRPIALLDNLHLGSLDNQRSLWLSRNIIKGISDYGNRIGVPVVGGETWFDESFNN
NPIVLVTCIGAGDFKRVIWGEGKVGDLVLVVGNDTGRDGMLGSSFASRELSSSDDIGAVQVGNPLLEKLLIDALMELGER
GLVKAIKDVGGGGLATALSELAHQLGLGIEVDLTNIRLRDELKPEEILVSESQERMIIVVDPSRLSYVEAVLRKYEVGFD
LIGKLTNDGKFTAYYKGIKLIDLPLDLITNPPEPIRKYTEPVYLMRLRRIPPLPSVKFNEALIKVASSPNLASKEVIYTQ
YDYEVGVRTVIKPGRAGATVLRLLEEDGGDGKLGIAVKADSNPRYSYLNPFTGAANSLAKAYRNVASVGAKPIAAVDSIN
VGNPEKPDKYWYFVKTVEGLTWMGNALGIPFVGGKVSFYNEDSVTGASIKPVVAVAVLGVVNDYAKAIEGGLTGEGWLVI
IGDTGPELGGSEFLHSVHGLVAGEPPEPKPLSEVKNANLVMQLINNGLAKAVMDVGVGGLAAALIKMSIIGGVGFTVDLS
KAPLTQGLNDPVTVAFSETNARYIIETSNLKETVRIIEANGVPYGVLGESGGGIVQFKWGGLELASLSVDDLVSINDSLR
GVI

Specific function: Unknown

COG id: COG0046

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGAMS family

Homologues:

Organism=Homo sapiens, GI31657129, Length=645, Percent_Identity=24.9612403100775, Blast_Score=99, Evalue=2e-20,
Organism=Escherichia coli, GI48994899, Length=745, Percent_Identity=24.1610738255034, Blast_Score=115, Evalue=7e-27,
Organism=Saccharomyces cerevisiae, GI6321498, Length=493, Percent_Identity=27.5862068965517, Blast_Score=123, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24582111, Length=717, Percent_Identity=25.2440725244073, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24582109, Length=717, Percent_Identity=25.2440725244073, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI17137292, Length=717, Percent_Identity=25.2440725244073, Blast_Score=100, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PURL_CALMQ (A8MCK2)

Other databases:

- EMBL:   CP000852
- RefSeq:   YP_001540498.1
- ProteinModelPortal:   A8MCK2
- SMR:   A8MCK2
- GeneID:   5710326
- GenomeReviews:   CP000852_GR
- KEGG:   cma:Cmaq_0668
- HOGENOM:   HBG311214
- OMA:   YGNSFGV
- ProtClustDB:   PRK01213
- BioCyc:   CMAQ397948:CMAQ_0668-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00420
- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR010074
- InterPro:   IPR016188
- TIGRFAMs:   TIGR01736

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C; SSF56042 AIR_synth_C; SSF55326 PurM_N-like

EC number: =6.3.5.3

Molecular weight: Translated: 77414; Mature: 77283

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLTSDEAKIIINTLGRNPTEAEWLIFEAEWSEHCSYKSSRAWIRLLPSKSPLVIRGSGL
CCCCCCCCEEEEEECCCCCCCCEEEEEECCHHHCCCCCCCCCEEEECCCCCCEEEECCCC
DAPIIRINNIAVTFKIESHNHPSAVDPYDGAATGVGGIVRDILTTGLRPIALLDNLHLGS
CCCEEEEEEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEHHCCCCCCC
LDNQRSLWLSRNIIKGISDYGNRIGVPVVGGETWFDESFNNNPIVLVTCIGAGDFKRVIW
CCCCHHHHHHHHHHHHHHHHCCEECCEEECCCCCCCCCCCCCCEEEEEEECCCCCEEEEE
GEGKVGDLVLVVGNDTGRDGMLGSSFASRELSSSDDIGAVQVGNPLLEKLLIDALMELGE
CCCCCCCEEEEEECCCCCCCCCCCCHHHCCCCCCCCCCEEECCCHHHHHHHHHHHHHHCC
RGLVKAIKDVGGGGLATALSELAHQLGLGIEVDLTNIRLRDELKPEEILVSESQERMIIV
CHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCHHEEECCCCCCEEEE
VDPSRLSYVEAVLRKYEVGFDLIGKLTNDGKFTAYYKGIKLIDLPLDLITNPPEPIRKYT
ECCCHHHHHHHHHHHHHCCHHHHHEECCCCEEEEEECCEEEEECCHHHHCCCCHHHHHHC
EPVYLMRLRRIPPLPSVKFNEALIKVASSPNLASKEVIYTQYDYEVGVRTVIKPGRAGAT
CHHHHHHHHCCCCCCCCCCCHHHEEEECCCCCCCCEEEEEEECCCCCCEEEECCCCCHHH
VLRLLEEDGGDGKLGIAVKADSNPRYSYLNPFTGAANSLAKAYRNVASVGAKPIAAVDSI
HHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCC
NVGNPEKPDKYWYFVKTVEGLTWMGNALGIPFVGGKVSFYNEDSVTGASIKPVVAVAVLG
CCCCCCCCCCEEEEEEEECCCEECCCCCCCCEECCEEEEECCCCCCCCCCHHHHHHHHHH
VVNDYAKAIEGGLTGEGWLVIIGDTGPELGGSEFLHSVHGLVAGEPPEPKPLSEVKNANL
HHHHHHHHHCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHCCHHH
VMQLINNGLAKAVMDVGVGGLAAALIKMSIIGGVGFTVDLSKAPLTQGLNDPVTVAFSET
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEECCCCCHHCCCCCCEEEEEECC
NARYIIETSNLKETVRIIEANGVPYGVLGESGGGIVQFKWGGLELASLSVDDLVSINDSL
CCEEEEEECCCCEEEEEEEECCCCEEEEECCCCCEEEEEECCEEEEECCHHHHHHCCCHH
RGVI
CCCC
>Mature Secondary Structure 
GLTSDEAKIIINTLGRNPTEAEWLIFEAEWSEHCSYKSSRAWIRLLPSKSPLVIRGSGL
CCCCCCCEEEEEECCCCCCCCEEEEEECCHHHCCCCCCCCCEEEECCCCCCEEEECCCC
DAPIIRINNIAVTFKIESHNHPSAVDPYDGAATGVGGIVRDILTTGLRPIALLDNLHLGS
CCCEEEEEEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEHHCCCCCCC
LDNQRSLWLSRNIIKGISDYGNRIGVPVVGGETWFDESFNNNPIVLVTCIGAGDFKRVIW
CCCCHHHHHHHHHHHHHHHHCCEECCEEECCCCCCCCCCCCCCEEEEEEECCCCCEEEEE
GEGKVGDLVLVVGNDTGRDGMLGSSFASRELSSSDDIGAVQVGNPLLEKLLIDALMELGE
CCCCCCCEEEEEECCCCCCCCCCCCHHHCCCCCCCCCCEEECCCHHHHHHHHHHHHHHCC
RGLVKAIKDVGGGGLATALSELAHQLGLGIEVDLTNIRLRDELKPEEILVSESQERMIIV
CHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCHHEEECCCCCCEEEE
VDPSRLSYVEAVLRKYEVGFDLIGKLTNDGKFTAYYKGIKLIDLPLDLITNPPEPIRKYT
ECCCHHHHHHHHHHHHHCCHHHHHEECCCCEEEEEECCEEEEECCHHHHCCCCHHHHHHC
EPVYLMRLRRIPPLPSVKFNEALIKVASSPNLASKEVIYTQYDYEVGVRTVIKPGRAGAT
CHHHHHHHHCCCCCCCCCCCHHHEEEECCCCCCCCEEEEEEECCCCCCEEEECCCCCHHH
VLRLLEEDGGDGKLGIAVKADSNPRYSYLNPFTGAANSLAKAYRNVASVGAKPIAAVDSI
HHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCC
NVGNPEKPDKYWYFVKTVEGLTWMGNALGIPFVGGKVSFYNEDSVTGASIKPVVAVAVLG
CCCCCCCCCCEEEEEEEECCCEECCCCCCCCEECCEEEEECCCCCCCCCCHHHHHHHHHH
VVNDYAKAIEGGLTGEGWLVIIGDTGPELGGSEFLHSVHGLVAGEPPEPKPLSEVKNANL
HHHHHHHHHCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHCCHHH
VMQLINNGLAKAVMDVGVGGLAAALIKMSIIGGVGFTVDLSKAPLTQGLNDPVTVAFSET
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEECCCCCHHCCCCCCEEEEEECC
NARYIIETSNLKETVRIIEANGVPYGVLGESGGGIVQFKWGGLELASLSVDDLVSINDSL
CCEEEEEECCCCEEEEEEEECCCCEEEEECCCCCEEEEEECCEEEEECCHHHHHHCCCHH
RGVI
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA