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The map label for this gene is pheS [H]

Identifier: 159041187

GI number: 159041187

Start: 641310

End: 642806

Strand: Reverse

Name: pheS [H]

Synonym: Cmaq_0608

Alternate gene names: 159041187

Gene position: 642806-641310 (Counterclockwise)

Preceding gene: 159041188

Following gene: 159041186

Centisome position: 30.94

GC content: 46.09

Gene sequence:

>1497_bases
ATGATTGTATTACCACCATTACAGTACAGTATAATTAAAGTGCTGGTTGAGGTTAATGAGCCTATTGACGCAGATTCCTT
AGCTAGTAAGGTGGGTAAGAGAACTGAGGACATTATGAGGGATCTTGAGGAACTTAAGGCAAGGGAGTTCATTAGAATTG
AATACCGGTTAGTCACGAGGATTGCGTTAACAGACCTTGGTGAAGAGTACTTAAGAATAGGCCTACCTGAGGAGAGGCTC
ATAGCCCGGTTAAGGGAATTGGGTGGTAAGGCTAACTTAAGTGAGTTAAGTCAATCAATGAATTTAAGTAAGGAGGAGCT
CACAGCCGCCTTGGGTAGGCTTAGGAGGCTTAAGGCAGTTAACCTAAGTGGTAGTGTAATTAACTTAACCGGTGATGAGG
GTGAATTCAGGAATTACATTAATGAACTTAAAACATTCCTAAACAACATTAAAGGTGAAGTAGAGTACACTGGTGAATTA
CCTGAATACGTAGAGGAGGCTAGGCGGAGGGGACTTGTTAAGGTTCATCAAGTGAAGAGACTCATAGTGGCTGCGACCCA
GGAGGCCTTAAACCTTTATAGGAGTGGTCAATTAACCAGTGCAAGGGTAATAACCAGCCTAACCTCAGCTGACTTAGCCT
CAGGTTCCTGGAGGGGCGGGGTCTTTAAGGAATTTGACTTAACGGTGGAGGTGCCTTTAAGGCCTATTAGGCGTAAGCAC
CCCTTCATTCAGTTCCTAAATCAGGTTAGAGATGAGTTAGTGGCCATGGGGTTTGAGGAGGTTAAGGATGAACACGTTGA
TGCAGCCTTATGGAACTTCGACACCCTCCTAGTGCCTCAATACCACCCGGCTAGACGTGAAACCGACGTATTCTACGTTG
AGAACAAGCTAAAGCCAAGGGAAGCCCCAGGGGAGGTTATGGAGAGGGCTAGTGAGCAGCATAGGTTAGTTTGGTCGTAT
GAGTGGAGTAGGGATGAGGCCCTTAGGGTACTTTTAAGAACACACACTACACTGGTTACTATTAAGCAGATTTACCATAG
GGGGCCGGGGGAGTATAGGTTGTTTTCACTTGATAGGGTTTACAGACCTGATACACCCGATGCCACGCACTTCATGGAGT
TTCACCAGCTTGAAGGCATAATAGTGGGTAGGGGGGTTACCTTCAGGAATCTACTGGGCTTCTTCACCGAGCTTGCTAAT
AGGCTTAGGCTTGGTAGGGTTTACTTTAAGCCGGCGTACTTCCCCTTCACTGAACCGAGCGTTGAAGGTTACGTGAAGCA
CCCGAAGCTTGGTCAACTTGAGGTTTTCCCCGGAGGCATGTTTAGACCTGAGGTGCTTAGGATAGTTGGCTTAGGTAGTG
AGTATAAGGTTGCGGCTTGGGGTGTTGGGATAGATAGGTTGGCAATGGTTGTCCTTGGCGTTGATGATATTAGAACCCTC
TACACTAATAATGTTAAGGAAATAGACTCAATGAAGACTCCCATTGGGGTGATTTAA

Upstream 100 bases:

>100_bases
ACGCTAAGTATGGTTCATTAAATGGCCCTGACCCACAATGCACATTAATGAACAGCTAGGTGTTAAGCTTAATAAGGGTT
GGTAAGCGGGGATGTAGAAT

Downstream 100 bases:

>100_bases
GTGCCGACTATTGAAGTCTCCTTAAGAGACCTATCCTCAATAGCGCGGGTTGATTTAACAATCAGTAGGCTGAGGGAGGT
TGTTGAGGTTCTTAAAGGTG

Product: phenylalanyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Phenylalanine--tRNA ligase alpha chain; PheRS [H]

Number of amino acids: Translated: 498; Mature: 498

Protein sequence:

>498_residues
MIVLPPLQYSIIKVLVEVNEPIDADSLASKVGKRTEDIMRDLEELKAREFIRIEYRLVTRIALTDLGEEYLRIGLPEERL
IARLRELGGKANLSELSQSMNLSKEELTAALGRLRRLKAVNLSGSVINLTGDEGEFRNYINELKTFLNNIKGEVEYTGEL
PEYVEEARRRGLVKVHQVKRLIVAATQEALNLYRSGQLTSARVITSLTSADLASGSWRGGVFKEFDLTVEVPLRPIRRKH
PFIQFLNQVRDELVAMGFEEVKDEHVDAALWNFDTLLVPQYHPARRETDVFYVENKLKPREAPGEVMERASEQHRLVWSY
EWSRDEALRVLLRTHTTLVTIKQIYHRGPGEYRLFSLDRVYRPDTPDATHFMEFHQLEGIIVGRGVTFRNLLGFFTELAN
RLRLGRVYFKPAYFPFTEPSVEGYVKHPKLGQLEVFPGGMFRPEVLRIVGLGSEYKVAAWGVGIDRLAMVVLGVDDIRTL
YTNNVKEIDSMKTPIGVI

Sequences:

>Translated_498_residues
MIVLPPLQYSIIKVLVEVNEPIDADSLASKVGKRTEDIMRDLEELKAREFIRIEYRLVTRIALTDLGEEYLRIGLPEERL
IARLRELGGKANLSELSQSMNLSKEELTAALGRLRRLKAVNLSGSVINLTGDEGEFRNYINELKTFLNNIKGEVEYTGEL
PEYVEEARRRGLVKVHQVKRLIVAATQEALNLYRSGQLTSARVITSLTSADLASGSWRGGVFKEFDLTVEVPLRPIRRKH
PFIQFLNQVRDELVAMGFEEVKDEHVDAALWNFDTLLVPQYHPARRETDVFYVENKLKPREAPGEVMERASEQHRLVWSY
EWSRDEALRVLLRTHTTLVTIKQIYHRGPGEYRLFSLDRVYRPDTPDATHFMEFHQLEGIIVGRGVTFRNLLGFFTELAN
RLRLGRVYFKPAYFPFTEPSVEGYVKHPKLGQLEVFPGGMFRPEVLRIVGLGSEYKVAAWGVGIDRLAMVVLGVDDIRTL
YTNNVKEIDSMKTPIGVI
>Mature_498_residues
MIVLPPLQYSIIKVLVEVNEPIDADSLASKVGKRTEDIMRDLEELKAREFIRIEYRLVTRIALTDLGEEYLRIGLPEERL
IARLRELGGKANLSELSQSMNLSKEELTAALGRLRRLKAVNLSGSVINLTGDEGEFRNYINELKTFLNNIKGEVEYTGEL
PEYVEEARRRGLVKVHQVKRLIVAATQEALNLYRSGQLTSARVITSLTSADLASGSWRGGVFKEFDLTVEVPLRPIRRKH
PFIQFLNQVRDELVAMGFEEVKDEHVDAALWNFDTLLVPQYHPARRETDVFYVENKLKPREAPGEVMERASEQHRLVWSY
EWSRDEALRVLLRTHTTLVTIKQIYHRGPGEYRLFSLDRVYRPDTPDATHFMEFHQLEGIIVGRGVTFRNLLGFFTELAN
RLRLGRVYFKPAYFPFTEPSVEGYVKHPKLGQLEVFPGGMFRPEVLRIVGLGSEYKVAAWGVGIDRLAMVVLGVDDIRTL
YTNNVKEIDSMKTPIGVI

Specific function: Unknown

COG id: COG0016

COG function: function code J; Phenylalanyl-tRNA synthetase alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha chain type 2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI4758340, Length=483, Percent_Identity=31.2629399585921, Blast_Score=202, Evalue=8e-52,
Organism=Escherichia coli, GI1788007, Length=311, Percent_Identity=30.8681672025724, Blast_Score=120, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI32563657, Length=296, Percent_Identity=35.8108108108108, Blast_Score=204, Evalue=7e-53,
Organism=Caenorhabditis elegans, GI17508957, Length=296, Percent_Identity=35.8108108108108, Blast_Score=204, Evalue=8e-53,
Organism=Saccharomyces cerevisiae, GI6321087, Length=508, Percent_Identity=28.9370078740157, Blast_Score=191, Evalue=3e-49,
Organism=Drosophila melanogaster, GI18858079, Length=319, Percent_Identity=36.0501567398119, Blast_Score=195, Evalue=6e-50,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006195
- InterPro:   IPR004529
- InterPro:   IPR022917
- InterPro:   IPR002319 [H]

Pfam domain/function: PF01409 tRNA-synt_2d [H]

EC number: =6.1.1.20 [H]

Molecular weight: Translated: 57042; Mature: 57042

Theoretical pI: Translated: 7.42; Mature: 7.42

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVLPPLQYSIIKVLVEVNEPIDADSLASKVGKRTEDIMRDLEELKAREFIRIEYRLVTR
CEEECCHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IALTDLGEEYLRIGLPEERLIARLRELGGKANLSELSQSMNLSKEELTAALGRLRRLKAV
HHHHHHCHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHEE
NLSGSVINLTGDEGEFRNYINELKTFLNNIKGEVEYTGELPEYVEEARRRGLVKVHQVKR
CCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHCCCHHHHHHHH
LIVAATQEALNLYRSGQLTSARVITSLTSADLASGSWRGGVFKEFDLTVEVPLRPIRRKH
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEECEEEECCCCHHHHCC
PFIQFLNQVRDELVAMGFEEVKDEHVDAALWNFDTLLVPQYHPARRETDVFYVENKLKPR
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCEEEEECCCCCC
EAPGEVMERASEQHRLVWSYEWSRDEALRVLLRTHTTLVTIKQIYHRGPGEYRLFSLDRV
CCCHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
YRPDTPDATHFMEFHQLEGIIVGRGVTFRNLLGFFTELANRLRLGRVYFKPAYFPFTEPS
CCCCCCCHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCC
VEGYVKHPKLGQLEVFPGGMFRPEVLRIVGLGSEYKVAAWGVGIDRLAMVVLGVDDIRTL
CCCCCCCCCCCCEEECCCCCCCHHHHHEEECCCCCEEEEECCCHHHHHHHHHCHHHHHHH
YTNNVKEIDSMKTPIGVI
HHCCHHHHHHHCCCCCCC
>Mature Secondary Structure
MIVLPPLQYSIIKVLVEVNEPIDADSLASKVGKRTEDIMRDLEELKAREFIRIEYRLVTR
CEEECCHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IALTDLGEEYLRIGLPEERLIARLRELGGKANLSELSQSMNLSKEELTAALGRLRRLKAV
HHHHHHCHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHEE
NLSGSVINLTGDEGEFRNYINELKTFLNNIKGEVEYTGELPEYVEEARRRGLVKVHQVKR
CCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHCCCHHHHHHHH
LIVAATQEALNLYRSGQLTSARVITSLTSADLASGSWRGGVFKEFDLTVEVPLRPIRRKH
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEECEEEECCCCHHHHCC
PFIQFLNQVRDELVAMGFEEVKDEHVDAALWNFDTLLVPQYHPARRETDVFYVENKLKPR
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCEEEEECCCCCC
EAPGEVMERASEQHRLVWSYEWSRDEALRVLLRTHTTLVTIKQIYHRGPGEYRLFSLDRV
CCCHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
YRPDTPDATHFMEFHQLEGIIVGRGVTFRNLLGFFTELANRLRLGRVYFKPAYFPFTEPS
CCCCCCCHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCC
VEGYVKHPKLGQLEVFPGGMFRPEVLRIVGLGSEYKVAAWGVGIDRLAMVVLGVDDIRTL
CCCCCCCCCCCCEEECCCCCCCHHHHHEEECCCCCEEEEECCCHHHHHHHHHCHHHHHHH
YTNNVKEIDSMKTPIGVI
HHCCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA