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The map label for this gene is gcp

Identifier: 159041172

GI number: 159041172

Start: 622847

End: 623842

Strand: Reverse

Name: gcp

Synonym: Cmaq_0593

Alternate gene names: 159041172

Gene position: 623842-622847 (Counterclockwise)

Preceding gene: 159041173

Following gene: 159041170

Centisome position: 30.03

GC content: 48.9

Gene sequence:

>996_bases
GTGATAATTCTCGGCATTGAATCCACAGCCCACACCATAGGGGTGGGGATAGTTAATGATAATGAGGTATTGGCTAATGA
GAATGAAACCTACACACCACCCCAGGGCTCAGGTATTCACCCAAGGGAGGCTGCGGATCATCACGCATTGAAGGCGTCGC
ATTTAGTTAAGAGGGCATTAGATAAGGCTGAGGTTAAATTAAGTGACCTTGATGCAGTGGCTTTTTCCCAGGGGCCTGGC
TTAGGACCAGCATTAAGGGTTGGGGCAACTGTGGCTAGGTTCATAGCCATTAAGTACGGTAAACCCCTTGTGCCTGTCCA
CCATGGGGTAGCCCACATTGAGATAGCTAAAATGACCACGGGTGCCAAGGACCCATTAGTACTCTTAGTCTCAGGTGGAC
ACACCATGGTAACCGCCTACTCAGGTGGTAGGTATAGGGTCTTTGGGGAGACAATGGATATATCAGTGGGTAATTGCCTC
GACATGTTCGCCAGATTCCTTGGCCTACCTAACCCAGGTGTACCACACCTTGAGGAATGCGCCAGGAGAGGTAAGGTAAT
GTTAGAGTTACCCTACACTGTTAAGGGACAGGACATGTCCTTCGCAGGCCTATACACTGCAGCAGTGAAGTTGGTTAAGG
AGGGGAGGAGGGTTGAGAATGTTTGCTTATCCATAGTTAACACGGCATACTACATGCTGGCTGAGGTGACTGAGAGGGCA
TTAGCACTACTGGGTAAGAGGGAGATAGTGATAGCCGGCGGCGTAGCCAGAAGCCCCATACTAAGAAGCATAATGGAGAT
CGTTGCATCAGAATACACGGCGACACTGCACGTTGTCCCCCCTGAGTATGCTGGTGATAATGGAGCTATGATTGCTTGGA
CTGGTTTACTGGCCTATAAAAGTGGCGTAAGCATTAGTATTGAGGATAGTGTAATTAAGCAGAGGTGGAGAATTGATGAA
GTCCCAATACCCTGGATTACCAGTACGGTTTCATGA

Upstream 100 bases:

>100_bases
CCGAGTAGAGGTAGGTGAAGGCTCAAATTAATGACTCTAAATCATAATAAATCCACTGGGTTGAGTGAGGATTTAAATAG
AACTAGGATTCGTGAGGCTT

Downstream 100 bases:

>100_bases
ATCTAGGTGGAGTAACCTGTTCTTAAATATGCATAAACCTGAATTAATGCCTCTGAGCCCTCTCTGCATTTTAATGTTAC
CAGTGGGAGCTTAAACCAAC

Product: metalloendopeptidase glycoprotease family

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MIILGIESTAHTIGVGIVNDNEVLANENETYTPPQGSGIHPREAADHHALKASHLVKRALDKAEVKLSDLDAVAFSQGPG
LGPALRVGATVARFIAIKYGKPLVPVHHGVAHIEIAKMTTGAKDPLVLLVSGGHTMVTAYSGGRYRVFGETMDISVGNCL
DMFARFLGLPNPGVPHLEECARRGKVMLELPYTVKGQDMSFAGLYTAAVKLVKEGRRVENVCLSIVNTAYYMLAEVTERA
LALLGKREIVIAGGVARSPILRSIMEIVASEYTATLHVVPPEYAGDNGAMIAWTGLLAYKSGVSISIEDSVIKQRWRIDE
VPIPWITSTVS

Sequences:

>Translated_331_residues
MIILGIESTAHTIGVGIVNDNEVLANENETYTPPQGSGIHPREAADHHALKASHLVKRALDKAEVKLSDLDAVAFSQGPG
LGPALRVGATVARFIAIKYGKPLVPVHHGVAHIEIAKMTTGAKDPLVLLVSGGHTMVTAYSGGRYRVFGETMDISVGNCL
DMFARFLGLPNPGVPHLEECARRGKVMLELPYTVKGQDMSFAGLYTAAVKLVKEGRRVENVCLSIVNTAYYMLAEVTERA
LALLGKREIVIAGGVARSPILRSIMEIVASEYTATLHVVPPEYAGDNGAMIAWTGLLAYKSGVSISIEDSVIKQRWRIDE
VPIPWITSTVS
>Mature_331_residues
MIILGIESTAHTIGVGIVNDNEVLANENETYTPPQGSGIHPREAADHHALKASHLVKRALDKAEVKLSDLDAVAFSQGPG
LGPALRVGATVARFIAIKYGKPLVPVHHGVAHIEIAKMTTGAKDPLVLLVSGGHTMVTAYSGGRYRVFGETMDISVGNCL
DMFARFLGLPNPGVPHLEECARRGKVMLELPYTVKGQDMSFAGLYTAAVKLVKEGRRVENVCLSIVNTAYYMLAEVTERA
LALLGKREIVIAGGVARSPILRSIMEIVASEYTATLHVVPPEYAGDNGAMIAWTGLLAYKSGVSISIEDSVIKQRWRIDE
VPIPWITSTVS

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family

Homologues:

Organism=Homo sapiens, GI8923380, Length=330, Percent_Identity=43.6363636363636, Blast_Score=275, Evalue=4e-74,
Organism=Homo sapiens, GI116812636, Length=342, Percent_Identity=28.0701754385965, Blast_Score=123, Evalue=2e-28,
Organism=Escherichia coli, GI1789445, Length=336, Percent_Identity=33.0357142857143, Blast_Score=165, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI71995670, Length=332, Percent_Identity=42.4698795180723, Blast_Score=275, Evalue=2e-74,
Organism=Caenorhabditis elegans, GI17557464, Length=325, Percent_Identity=29.8461538461538, Blast_Score=104, Evalue=5e-23,
Organism=Saccharomyces cerevisiae, GI6322891, Length=368, Percent_Identity=36.6847826086957, Blast_Score=236, Evalue=4e-63,
Organism=Saccharomyces cerevisiae, GI6320099, Length=366, Percent_Identity=26.5027322404372, Blast_Score=108, Evalue=2e-24,
Organism=Drosophila melanogaster, GI21357207, Length=340, Percent_Identity=42.0588235294118, Blast_Score=280, Evalue=1e-75,
Organism=Drosophila melanogaster, GI20129063, Length=365, Percent_Identity=28.4931506849315, Blast_Score=119, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_CALMQ (A8MCC8)

Other databases:

- EMBL:   CP000852
- RefSeq:   YP_001540424.1
- ProteinModelPortal:   A8MCC8
- SMR:   A8MCC8
- MEROPS:   M22.003
- GeneID:   5709352
- GenomeReviews:   CP000852_GR
- KEGG:   cma:Cmaq_0593
- HOGENOM:   HBG304663
- OMA:   TQRFRTD
- ProtClustDB:   PRK14878
- BioCyc:   CMAQ397948:CMAQ_0593-MONOMER
- GO:   GO:0006508
- HAMAP:   MF_01446
- InterPro:   IPR022449
- InterPro:   IPR000905
- InterPro:   IPR017861
- PANTHER:   PTHR11735
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03722
- TIGRFAMs:   TIGR00329

Pfam domain/function: PF00814 Peptidase_M22

EC number: =3.4.24.57

Molecular weight: Translated: 35559; Mature: 35559

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIILGIESTAHTIGVGIVNDNEVLANENETYTPPQGSGIHPREAADHHALKASHLVKRAL
CEEEEECCCCEEEEEEEECCCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
DKAEVKLSDLDAVAFSQGPGLGPALRVGATVARFIAIKYGKPLVPVHHGVAHIEIAKMTT
HHHHEEHHHCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECC
GAKDPLVLLVSGGHTMVTAYSGGRYRVFGETMDISVGNCLDMFARFLGLPNPGVPHLEEC
CCCCCEEEEEECCCEEEEEECCCEEEEECCEEEECCHHHHHHHHHHHCCCCCCCCHHHHH
ARRGKVMLELPYTVKGQDMSFAGLYTAAVKLVKEGRRVENVCLSIVNTAYYMLAEVTERA
HHCCCEEEEECCEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
LALLGKREIVIAGGVARSPILRSIMEIVASEYTATLHVVPPEYAGDNGAMIAWTGLLAYK
HHHHCCCEEEEECCCHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCEEEEEEEHHHH
SGVSISIEDSVIKQRWRIDEVPIPWITSTVS
CCCEEEEHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIILGIESTAHTIGVGIVNDNEVLANENETYTPPQGSGIHPREAADHHALKASHLVKRAL
CEEEEECCCCEEEEEEEECCCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
DKAEVKLSDLDAVAFSQGPGLGPALRVGATVARFIAIKYGKPLVPVHHGVAHIEIAKMTT
HHHHEEHHHCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECC
GAKDPLVLLVSGGHTMVTAYSGGRYRVFGETMDISVGNCLDMFARFLGLPNPGVPHLEEC
CCCCCEEEEEECCCEEEEEECCCEEEEECCEEEECCHHHHHHHHHHHCCCCCCCCHHHHH
ARRGKVMLELPYTVKGQDMSFAGLYTAAVKLVKEGRRVENVCLSIVNTAYYMLAEVTERA
HHCCCEEEEECCEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
LALLGKREIVIAGGVARSPILRSIMEIVASEYTATLHVVPPEYAGDNGAMIAWTGLLAYK
HHHHCCCEEEEECCCHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCEEEEEEEHHHH
SGVSISIEDSVIKQRWRIDEVPIPWITSTVS
CCCEEEEHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA