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The map label for this gene is eIF1A [H]

Identifier: 159041129

GI number: 159041129

Start: 581466

End: 581774

Strand: Reverse

Name: eIF1A [H]

Synonym: Cmaq_0548

Alternate gene names: 159041129

Gene position: 581774-581466 (Counterclockwise)

Preceding gene: 159041131

Following gene: 159041128

Centisome position: 28.0

GC content: 43.04

Gene sequence:

>309_bases
GTGAGTGCAGAGTCTAAGGTTAGGGTTCCGGATGAGGGGGAGATGCTTGCTAAGGTTACTGACATAGTTGGGGATGATAG
AGTTAAGGTTGTTTGCGAGGATGGTAACGTCAGGATAGCTAGGATTCCAGGTAAGTATAGGAAGAGGATGTGGATTAGGA
TTGGGGATTATTTAATCGTTGCTCCATGGGATTTTGAACCCAGCAAGGCTGATGTTGTTTATAAGTATGAGAAGGGTGAG
GTTAATGAACTTAGGAGGATTAGTAAGTACAGTGAGGTTTTAAATAGGCTTGATGAATTAGCCCTGTAG

Upstream 100 bases:

>100_bases
CTCAGAGTCACGTATACGTATACTACACGTATACGTGTAGAGTAGGGTTAATTATATTGATTGACGGGAGGTTTATTAAG
AGTCCTGGGGCTGGGTTCCT

Downstream 100 bases:

>100_bases
CGTGATGGATCAACAGGAATTAAATAGATTAAGGGACCTGGTTAAGATGGAGCAGGAGAGTAAGGAGCTTGTGAAGTTAC
CCTACAGGTCCTATAGGGAG

Product: translation initiation factor IF-1A

Products: NA

Alternate protein names: aIF-1A [H]

Number of amino acids: Translated: 102; Mature: 101

Protein sequence:

>102_residues
MSAESKVRVPDEGEMLAKVTDIVGDDRVKVVCEDGNVRIARIPGKYRKRMWIRIGDYLIVAPWDFEPSKADVVYKYEKGE
VNELRRISKYSEVLNRLDELAL

Sequences:

>Translated_102_residues
MSAESKVRVPDEGEMLAKVTDIVGDDRVKVVCEDGNVRIARIPGKYRKRMWIRIGDYLIVAPWDFEPSKADVVYKYEKGE
VNELRRISKYSEVLNRLDELAL
>Mature_101_residues
SAESKVRVPDEGEMLAKVTDIVGDDRVKVVCEDGNVRIARIPGKYRKRMWIRIGDYLIVAPWDFEPSKADVVYKYEKGEV
NELRRISKYSEVLNRLDELAL

Specific function: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits [H]

COG id: COG0361

COG function: function code J; Translation initiation factor 1 (IF-1)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1-like domain [H]

Homologues:

Organism=Caenorhabditis elegans, GI17540984, Length=77, Percent_Identity=37.6623376623377, Blast_Score=65, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6323916, Length=94, Percent_Identity=36.1702127659575, Blast_Score=69, Evalue=1e-13,
Organism=Drosophila melanogaster, GI45553405, Length=83, Percent_Identity=38.5542168674699, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24647907, Length=83, Percent_Identity=38.5542168674699, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR006196
- InterPro:   IPR001253
- InterPro:   IPR018104
- ProDom:   PD005579 [H]

Pfam domain/function: PF01176 eIF-1a [H]

EC number: NA

Molecular weight: Translated: 11802; Mature: 11671

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS50832 S1_IF1_TYPE ; PS01262 IF1A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAESKVRVPDEGEMLAKVTDIVGDDRVKVVCEDGNVRIARIPGKYRKRMWIRIGDYLIV
CCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCEEEEECCCHHHHEEEEEECCEEEE
APWDFEPSKADVVYKYEKGEVNELRRISKYSEVLNRLDELAL
ECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SAESKVRVPDEGEMLAKVTDIVGDDRVKVVCEDGNVRIARIPGKYRKRMWIRIGDYLIV
CCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCEEEEECCCHHHHEEEEEECCEEEE
APWDFEPSKADVVYKYEKGEVNELRRISKYSEVLNRLDELAL
ECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014 [H]