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The map label for this gene is srp54 [H]

Identifier: 159040882

GI number: 159040882

Start: 334003

End: 335352

Strand: Reverse

Name: srp54 [H]

Synonym: Cmaq_0296

Alternate gene names: 159040882

Gene position: 335352-334003 (Counterclockwise)

Preceding gene: 159040883

Following gene: 159040881

Centisome position: 16.14

GC content: 44.89

Gene sequence:

>1350_bases
ATGAGAGACTTAATGGACGCCATAGGCAGCATAATAAGTAGGATCAGGGGCTCAACCTTAATTGATGAGGAAACCCTAAG
GAGCATACTTAGGGATCTGCAGAGGGCATTAATAAGGGCTGACGTCGACGTTAAGCTGGTTTACGAATTAACCAAGAGCA
TTGAGGAGGAGTTTAAGGAGGCTAAGGAACTCCCCCCAGGCTTAACAGCTAAGGACTATTTGGTTTACTTACTTTACAGG
AAACTCACCGACCTACTTGGTGGTGATAAGGAGCCTGACGTTGAGGTTAAGACCAAGCCCTACATACTAATGCTGGTGGG
TACTGAGGGTAGTGGTAAAACAACCACGGCAGGTAAGTTAGCTAACTTCTACATTAAGAGGGGGCTTAAGGTTGGTTTAA
TTGAGACTGACACCATTAGGCCTGGGGCCTTTGACCAGTTGAGGCAATTAGCTGAGAGGGTTAAGGCAATGTTCTTCGGT
GACCCAAGCCTAGGCAACGCCGTTAACATAGCTAAGGCTGGTTTAAGTAGAATGATTAGCAGTAAGGCTGATTTAATAAT
AATAGATACTGCTGGTAGGCATAGGAATGAGGAGGAGCTCCTCAGTGAGGTTAAGGAGATTTACGAGGCCGTGAAGCCCA
ATGAAGTAATGCTTGTTGTTGATGCAACCAATGGTAAGCAGGTTGGGGCTCAGGCAGAGGCCTTCAGTAAGTATGTTCCA
GTTAACTCAATATTCATAACTAAACTCGACAGTACGGCTAAGGGGGGTGGGGCCCTTGTATCCGCGGTTAAGACTGGGGC
TAGAATTAAGTTCATTGGTAATGGTGAGGATATTGAGGATATTGAGGTCTTTAACCCAAGGAGGTTTGTGGCTAGGTTAA
TGGGCATGGGTGATGTTGAGTCACTCCTGGATAAGGTTAAGGCAATGGAGGAGGAGGAAGAGGTTCTTGAGGATATTGAA
ACCGGTAAGTTCACCTTATTAACATTAATGAAGCAGCTTGAAGCCATGGGTAAACTCGGCCCATTAAGTAGGATTCTTCA
AATGCTCCCCATGGGGTTAATGCCTCAGTTAAAGGAATTGAATGATGATCAACTAATGAACGCCCAGGACAGGATGAGGA
AGTGGTTATCAATATTGAGATCAATGACTAAGGAGGAGTTACTTAACCCAAATATATTAAACGCATCAAGGATTAGGAGA
ATAGCCAAGGGCTCAGGGGTGACGCCGAGGGATGTTAGGGAATTACTGAGGTACTATAATGAGATGAGTAGAATGATGAG
TAGCCTTAAGAAGAGTCAACGCAGGTTGGGAAGCCTATTCAGGAGATTCAGCATTAATCAGGGTCAGTAA

Upstream 100 bases:

>100_bases
GGAATAATCATAAGGGGTACTTTAACTGATGTGCTTAGGTACGTTCAGCAAAGCATGTACCAGTACAGTTACTACCCATA
CACAACCCAGTGATTGATTA

Downstream 100 bases:

>100_bases
GGGGTGAACCAATCACTCCTCATTCCGGAAACCTTCTCATCACTAACAGCAATATTAGGGTGCCCTTAAATAAACTTAGG
CTTAATTAAAGTGATGAACA

Product: GTP-binding signal recognition particle

Products: NA

Alternate protein names: SRP54 [H]

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MRDLMDAIGSIISRIRGSTLIDEETLRSILRDLQRALIRADVDVKLVYELTKSIEEEFKEAKELPPGLTAKDYLVYLLYR
KLTDLLGGDKEPDVEVKTKPYILMLVGTEGSGKTTTAGKLANFYIKRGLKVGLIETDTIRPGAFDQLRQLAERVKAMFFG
DPSLGNAVNIAKAGLSRMISSKADLIIIDTAGRHRNEEELLSEVKEIYEAVKPNEVMLVVDATNGKQVGAQAEAFSKYVP
VNSIFITKLDSTAKGGGALVSAVKTGARIKFIGNGEDIEDIEVFNPRRFVARLMGMGDVESLLDKVKAMEEEEEVLEDIE
TGKFTLLTLMKQLEAMGKLGPLSRILQMLPMGLMPQLKELNDDQLMNAQDRMRKWLSILRSMTKEELLNPNILNASRIRR
IAKGSGVTPRDVRELLRYYNEMSRMMSSLKKSQRRLGSLFRRFSINQGQ

Sequences:

>Translated_449_residues
MRDLMDAIGSIISRIRGSTLIDEETLRSILRDLQRALIRADVDVKLVYELTKSIEEEFKEAKELPPGLTAKDYLVYLLYR
KLTDLLGGDKEPDVEVKTKPYILMLVGTEGSGKTTTAGKLANFYIKRGLKVGLIETDTIRPGAFDQLRQLAERVKAMFFG
DPSLGNAVNIAKAGLSRMISSKADLIIIDTAGRHRNEEELLSEVKEIYEAVKPNEVMLVVDATNGKQVGAQAEAFSKYVP
VNSIFITKLDSTAKGGGALVSAVKTGARIKFIGNGEDIEDIEVFNPRRFVARLMGMGDVESLLDKVKAMEEEEEVLEDIE
TGKFTLLTLMKQLEAMGKLGPLSRILQMLPMGLMPQLKELNDDQLMNAQDRMRKWLSILRSMTKEELLNPNILNASRIRR
IAKGSGVTPRDVRELLRYYNEMSRMMSSLKKSQRRLGSLFRRFSINQGQ
>Mature_449_residues
MRDLMDAIGSIISRIRGSTLIDEETLRSILRDLQRALIRADVDVKLVYELTKSIEEEFKEAKELPPGLTAKDYLVYLLYR
KLTDLLGGDKEPDVEVKTKPYILMLVGTEGSGKTTTAGKLANFYIKRGLKVGLIETDTIRPGAFDQLRQLAERVKAMFFG
DPSLGNAVNIAKAGLSRMISSKADLIIIDTAGRHRNEEELLSEVKEIYEAVKPNEVMLVVDATNGKQVGAQAEAFSKYVP
VNSIFITKLDSTAKGGGALVSAVKTGARIKFIGNGEDIEDIEVFNPRRFVARLMGMGDVESLLDKVKAMEEEEEVLEDIE
TGKFTLLTLMKQLEAMGKLGPLSRILQMLPMGLMPQLKELNDDQLMNAQDRMRKWLSILRSMTKEELLNPNILNASRIRR
IAKGSGVTPRDVRELLRYYNEMSRMMSSLKKSQRRLGSLFRRFSINQGQ

Specific function: Binds to the signal sequence of presecretory protein when they emerge from the ribosomes [H]

COG id: COG0541

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=436, Percent_Identity=36.2385321100917, Blast_Score=293, Evalue=2e-79,
Organism=Homo sapiens, GI226371618, Length=375, Percent_Identity=37.0666666666667, Blast_Score=262, Evalue=4e-70,
Organism=Homo sapiens, GI89061728, Length=159, Percent_Identity=40.251572327044, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI23308697, Length=309, Percent_Identity=23.6245954692557, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI295424842, Length=309, Percent_Identity=23.6245954692557, Blast_Score=88, Evalue=2e-17,
Organism=Escherichia coli, GI1788963, Length=429, Percent_Identity=32.4009324009324, Blast_Score=216, Evalue=2e-57,
Organism=Escherichia coli, GI1789874, Length=238, Percent_Identity=36.9747899159664, Blast_Score=125, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI17539958, Length=430, Percent_Identity=35.8139534883721, Blast_Score=278, Evalue=6e-75,
Organism=Caenorhabditis elegans, GI193206261, Length=220, Percent_Identity=25.4545454545455, Blast_Score=69, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6325345, Length=446, Percent_Identity=36.5470852017937, Blast_Score=278, Evalue=1e-75,
Organism=Saccharomyces cerevisiae, GI6320498, Length=330, Percent_Identity=27.8787878787879, Blast_Score=104, Evalue=2e-23,
Organism=Drosophila melanogaster, GI17647949, Length=441, Percent_Identity=35.3741496598639, Blast_Score=266, Evalue=3e-71,
Organism=Drosophila melanogaster, GI24641198, Length=220, Percent_Identity=25.4545454545455, Blast_Score=81, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822
- InterPro:   IPR004125
- InterPro:   IPR022941 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N; PF02978 SRP_SPB [H]

EC number: NA

Molecular weight: Translated: 50339; Mature: 50339

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDLMDAIGSIISRIRGSTLIDEETLRSILRDLQRALIRADVDVKLVYELTKSIEEEFKE
CHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
AKELPPGLTAKDYLVYLLYRKLTDLLGGDKEPDVEVKTKPYILMLVGTEGSGKTTTAGKL
HHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCEEEEEEECCCCCCCCHHHHH
ANFYIKRGLKVGLIETDTIRPGAFDQLRQLAERVKAMFFGDPSLGNAVNIAKAGLSRMIS
HHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHC
SKADLIIIDTAGRHRNEEELLSEVKEIYEAVKPNEVMLVVDATNGKQVGAQAEAFSKYVP
CCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHCC
VNSIFITKLDSTAKGGGALVSAVKTGARIKFIGNGEDIEDIEVFNPRRFVARLMGMGDVE
CCEEEEEECCCCCCCCHHHHHHHHCCCEEEEECCCCCCCHHHHCCHHHHHHHHHCCCCHH
SLLDKVKAMEEEEEVLEDIETGKFTLLTLMKQLEAMGKLGPLSRILQMLPMGLMPQLKEL
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHC
NDDQLMNAQDRMRKWLSILRSMTKEELLNPNILNASRIRRIAKGSGVTPRDVRELLRYYN
CHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHH
EMSRMMSSLKKSQRRLGSLFRRFSINQGQ
HHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MRDLMDAIGSIISRIRGSTLIDEETLRSILRDLQRALIRADVDVKLVYELTKSIEEEFKE
CHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
AKELPPGLTAKDYLVYLLYRKLTDLLGGDKEPDVEVKTKPYILMLVGTEGSGKTTTAGKL
HHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCEEEEEEECCCCCCCCHHHHH
ANFYIKRGLKVGLIETDTIRPGAFDQLRQLAERVKAMFFGDPSLGNAVNIAKAGLSRMIS
HHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHC
SKADLIIIDTAGRHRNEEELLSEVKEIYEAVKPNEVMLVVDATNGKQVGAQAEAFSKYVP
CCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHCC
VNSIFITKLDSTAKGGGALVSAVKTGARIKFIGNGEDIEDIEVFNPRRFVARLMGMGDVE
CCEEEEEECCCCCCCCHHHHHHHHCCCEEEEECCCCCCCHHHHCCHHHHHHHHHCCCCHH
SLLDKVKAMEEEEEVLEDIETGKFTLLTLMKQLEAMGKLGPLSRILQMLPMGLMPQLKEL
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHC
NDDQLMNAQDRMRKWLSILRSMTKEELLNPNILNASRIRRIAKGSGVTPRDVRELLRYYN
CHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHH
EMSRMMSSLKKSQRRLGSLFRRFSINQGQ
HHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA