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The map label for this gene is eriC [C]

Identifier: 159040763

GI number: 159040763

Start: 209596

End: 211356

Strand: Reverse

Name: eriC [C]

Synonym: Cmaq_0176

Alternate gene names: 159040763

Gene position: 211356-209596 (Counterclockwise)

Preceding gene: 159040768

Following gene: 159040762

Centisome position: 10.17

GC content: 45.49

Gene sequence:

>1761_bases
ATGAACATTAGTGAGTTGCCGTATTATGTCAAGTGGTTTATTTTAGGAATCGTGATTGGTGTGGTTGCTGGTTTATCGGC
ATTAGCCTTCTACTTCACTTTAAAGTTCATGGAGTACTTATTCATGGTTAGGTTAATTGCTTTTAAACCACCTCTACCCA
TAGGGGAGGGTGGTTCATTAAACTACGTACTTCATGCAGGTAGGCTTTGGTTAATACCGGTGTCCACTGCCTTAGGTGGG
TTACTTTCAGGTTTAATAGTGTATACCTGGGCTCCTGAGGCTGAGGGTCATGGGACTGATGCGGCGATTAATGCCTTTCA
TAGGCTTCAAGGCAGGATTAGAAGGAGAATACCGCCTATTAAACTCATAGCCTCAGCCATAACGATTGGGTCAGGGGGAA
GTGCCGGTAGGGAGGGGCCCACGGCTCAATTAAGCGCTGGTATTGGGTCGTTTATAGCCGATTTATTAGGCTTATCTGCT
GAGGATAGGAGGATTGCTGTTGCTGTTGGTATTGGTGCTGGTATTGGTTCAATATTTAAGGCACCCATGGGTGGAGCAAT
ATTAGCGGCTGAGGTGCTTTATAAGAGGGATATGGAGACTGAGGTCTTATTCCCGGCCCTAGTGGCCTCAGTGGTGGGTT
ACTCAATATTTAGCTCCATTGTTGGCTTCACCCCAATATTCGGGTACTACACCGGTGTCTTCAATCCATTAAGGTTACCA
TTATACGCCGTTCTCGGTATAGTGGATGGATTAGTAGCGGTACTTTACGTGAAGACCTTCTACTTCATTCACGACTCCTT
CAAGAGGTGGAGGATTAGCAACTACGTGAAACCTGTAATTGGTGGCCTTGCCACTGGTTTAATAGGCCTACTGGTGCCTG
AAATATTAGGCACTGGTTATGGTTGGGTTAACTTAGCTGAGTTCAATAATGTTAATGCATTTGCGTCACCAGTACTAATA
CCACCGCTTATGATTCTAATACTGCTACCATTCCTCAAGATTATTGCAACATCATTCACAGTAGGTTCAGGTGGTAGTGG
TGGTGTCTTTGCGCCAGGCATAGTGATAGGGGCTTTCACTGGTTTTGATGCTTGGCTTCTTTTCCACTACCTGACACCAG
GCTTAACCCCTAATCCTGCGCCATTTGTAATAGTGAGTATGCTTGCGCTCTTCGGGGCTTCTGCTAAAGCCCCCTTGGCG
GTAATGTTCATGGTTATTGAAATGACGGGTAGTTATCAATTATTGCCTGCAGCCATGATAGCCGTGGCAATAGCCTACAT
AGTATCAGGTGACTATACGATATATAGGGCCCAAGTCCCAACTAGGAGGGATTCCCCAGCCCATGCTAATGAATACAAGG
TACCACTCATCATGGAGCTTAAGGTTAAGGATTGTAGAATAATTAAGGGACCTGTGGTGAGTCCAAGTGATGATGCTGGT
AAAGCCTTAAACACAATGCTTAGACTCAGGTACACGGCGTTGCCTGTTGTTGATGATGGGAGGTTCATAGGCTTGATCAG
TATCTATAACATGAATGGTGGCAGGGGGAAGGTTAGTGACTACATTATTAGGGATACCCAGTACGTGACCCCTGAGTCCA
CGCTTTACGATGCATTAACAGTTATGAGTAAACTGGGCACCACCTGGGTACCAGTGGTGAGTAACGGTGAGTTCCTGGGG
ATACTAACCATGGAGAACATGAATAAGGCTTACACCGAGAGATTAAGAAGCCTAATGCCCAATAAGCAACCATATCATTA
A

Upstream 100 bases:

>100_bases
TTACGATTTATTAATTAAATGAGAACCAATGATGCTGGGTTTAAAGGGTAATGATGTTGTACAATAAGCCTTATAAATGC
CTTAATTCCTCAGCGTATTA

Downstream 100 bases:

>100_bases
TGGATACGGTTTTAATTCATTAAGTGGTGTGTTTAATAAGGGGGAATAGTGCCTAAGCCTGTGCCCGTTAAGAAGACCCT
TAATGCGCTTGACTTAGTGG

Product: chloride channel protein

Products: Cl Ion [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 586; Mature: 586

Protein sequence:

>586_residues
MNISELPYYVKWFILGIVIGVVAGLSALAFYFTLKFMEYLFMVRLIAFKPPLPIGEGGSLNYVLHAGRLWLIPVSTALGG
LLSGLIVYTWAPEAEGHGTDAAINAFHRLQGRIRRRIPPIKLIASAITIGSGGSAGREGPTAQLSAGIGSFIADLLGLSA
EDRRIAVAVGIGAGIGSIFKAPMGGAILAAEVLYKRDMETEVLFPALVASVVGYSIFSSIVGFTPIFGYYTGVFNPLRLP
LYAVLGIVDGLVAVLYVKTFYFIHDSFKRWRISNYVKPVIGGLATGLIGLLVPEILGTGYGWVNLAEFNNVNAFASPVLI
PPLMILILLPFLKIIATSFTVGSGGSGGVFAPGIVIGAFTGFDAWLLFHYLTPGLTPNPAPFVIVSMLALFGASAKAPLA
VMFMVIEMTGSYQLLPAAMIAVAIAYIVSGDYTIYRAQVPTRRDSPAHANEYKVPLIMELKVKDCRIIKGPVVSPSDDAG
KALNTMLRLRYTALPVVDDGRFIGLISIYNMNGGRGKVSDYIIRDTQYVTPESTLYDALTVMSKLGTTWVPVVSNGEFLG
ILTMENMNKAYTERLRSLMPNKQPYH

Sequences:

>Translated_586_residues
MNISELPYYVKWFILGIVIGVVAGLSALAFYFTLKFMEYLFMVRLIAFKPPLPIGEGGSLNYVLHAGRLWLIPVSTALGG
LLSGLIVYTWAPEAEGHGTDAAINAFHRLQGRIRRRIPPIKLIASAITIGSGGSAGREGPTAQLSAGIGSFIADLLGLSA
EDRRIAVAVGIGAGIGSIFKAPMGGAILAAEVLYKRDMETEVLFPALVASVVGYSIFSSIVGFTPIFGYYTGVFNPLRLP
LYAVLGIVDGLVAVLYVKTFYFIHDSFKRWRISNYVKPVIGGLATGLIGLLVPEILGTGYGWVNLAEFNNVNAFASPVLI
PPLMILILLPFLKIIATSFTVGSGGSGGVFAPGIVIGAFTGFDAWLLFHYLTPGLTPNPAPFVIVSMLALFGASAKAPLA
VMFMVIEMTGSYQLLPAAMIAVAIAYIVSGDYTIYRAQVPTRRDSPAHANEYKVPLIMELKVKDCRIIKGPVVSPSDDAG
KALNTMLRLRYTALPVVDDGRFIGLISIYNMNGGRGKVSDYIIRDTQYVTPESTLYDALTVMSKLGTTWVPVVSNGEFLG
ILTMENMNKAYTERLRSLMPNKQPYH
>Mature_586_residues
MNISELPYYVKWFILGIVIGVVAGLSALAFYFTLKFMEYLFMVRLIAFKPPLPIGEGGSLNYVLHAGRLWLIPVSTALGG
LLSGLIVYTWAPEAEGHGTDAAINAFHRLQGRIRRRIPPIKLIASAITIGSGGSAGREGPTAQLSAGIGSFIADLLGLSA
EDRRIAVAVGIGAGIGSIFKAPMGGAILAAEVLYKRDMETEVLFPALVASVVGYSIFSSIVGFTPIFGYYTGVFNPLRLP
LYAVLGIVDGLVAVLYVKTFYFIHDSFKRWRISNYVKPVIGGLATGLIGLLVPEILGTGYGWVNLAEFNNVNAFASPVLI
PPLMILILLPFLKIIATSFTVGSGGSGGVFAPGIVIGAFTGFDAWLLFHYLTPGLTPNPAPFVIVSMLALFGASAKAPLA
VMFMVIEMTGSYQLLPAAMIAVAIAYIVSGDYTIYRAQVPTRRDSPAHANEYKVPLIMELKVKDCRIIKGPVVSPSDDAG
KALNTMLRLRYTALPVVDDGRFIGLISIYNMNGGRGKVSDYIIRDTQYVTPESTLYDALTVMSKLGTTWVPVVSNGEFLG
ILTMENMNKAYTERLRSLMPNKQPYH

Specific function: Selective chloride channel [C]

COG id: COG0038

COG function: function code P; Chloride channel protein EriC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chloride channel (TC 2.A.49) family. ClcB subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786350, Length=408, Percent_Identity=27.2058823529412, Blast_Score=99, Evalue=9e-22,
Organism=Escherichia coli, GI87081943, Length=338, Percent_Identity=28.9940828402367, Blast_Score=92, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014743
- InterPro:   IPR001807 [H]

Pfam domain/function: PF00654 Voltage_CLC [H]

EC number: NA

Molecular weight: Translated: 63159; Mature: 63159

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNISELPYYVKWFILGIVIGVVAGLSALAFYFTLKFMEYLFMVRLIAFKPPLPIGEGGSL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCE
NYVLHAGRLWLIPVSTALGGLLSGLIVYTWAPEAEGHGTDAAINAFHRLQGRIRRRIPPI
EEEEECCEEEEEEHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCHH
KLIASAITIGSGGSAGREGPTAQLSAGIGSFIADLLGLSAEDRRIAVAVGIGAGIGSIFK
HHHHHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCHHHHHH
APMGGAILAAEVLYKRDMETEVLFPALVASVVGYSIFSSIVGFTPIFGYYTGVFNPLRLP
CCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
LYAVLGIVDGLVAVLYVKTFYFIHDSFKRWRISNYVKPVIGGLATGLIGLLVPEILGTGY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GWVNLAEFNNVNAFASPVLIPPLMILILLPFLKIIATSFTVGSGGSGGVFAPGIVIGAFT
CEEEEECCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCHHHEEHHC
GFDAWLLFHYLTPGLTPNPAPFVIVSMLALFGASAKAPLAVMFMVIEMTGSYQLLPAAMI
CHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHH
AVAIAYIVSGDYTIYRAQVPTRRDSPAHANEYKVPLIMELKVKDCRIIKGPVVSPSDDAG
HHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCEEEECCCCCCCCHHH
KALNTMLRLRYTALPVVDDGRFIGLISIYNMNGGRGKVSDYIIRDTQYVTPESTLYDALT
HHHHHHHHHHHHCCEEECCCCEEEEEEEEECCCCCCCHHHEEEECCEECCCCHHHHHHHH
VMSKLGTTWVPVVSNGEFLGILTMENMNKAYTERLRSLMPNKQPYH
HHHHCCCCEEEEECCCCEEEEEEHHHCCHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNISELPYYVKWFILGIVIGVVAGLSALAFYFTLKFMEYLFMVRLIAFKPPLPIGEGGSL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCE
NYVLHAGRLWLIPVSTALGGLLSGLIVYTWAPEAEGHGTDAAINAFHRLQGRIRRRIPPI
EEEEECCEEEEEEHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCHH
KLIASAITIGSGGSAGREGPTAQLSAGIGSFIADLLGLSAEDRRIAVAVGIGAGIGSIFK
HHHHHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCHHHHHH
APMGGAILAAEVLYKRDMETEVLFPALVASVVGYSIFSSIVGFTPIFGYYTGVFNPLRLP
CCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
LYAVLGIVDGLVAVLYVKTFYFIHDSFKRWRISNYVKPVIGGLATGLIGLLVPEILGTGY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GWVNLAEFNNVNAFASPVLIPPLMILILLPFLKIIATSFTVGSGGSGGVFAPGIVIGAFT
CEEEEECCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCHHHEEHHC
GFDAWLLFHYLTPGLTPNPAPFVIVSMLALFGASAKAPLAVMFMVIEMTGSYQLLPAAMI
CHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHH
AVAIAYIVSGDYTIYRAQVPTRRDSPAHANEYKVPLIMELKVKDCRIIKGPVVSPSDDAG
HHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCEEEECCCCCCCCHHH
KALNTMLRLRYTALPVVDDGRFIGLISIYNMNGGRGKVSDYIIRDTQYVTPESTLYDALT
HHHHHHHHHHHHCCEEECCCCEEEEEEEEECCCCCCCHHHEEEECCEECCCCHHHHHHHH
VMSKLGTTWVPVVSNGEFLGILTMENMNKAYTERLRSLMPNKQPYH
HHHHCCCCEEEEECCCCEEEEEEHHHCCHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Cl Ion [Periplasm] [C]

Specific reaction: Cl Ion [Periplasm] = Cl Ion [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]