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The map label for this gene is cph2 [H]

Identifier: 158425595

GI number: 158425595

Start: 4538945

End: 4540594

Strand: Direct

Name: cph2 [H]

Synonym: AZC_3971

Alternate gene names: 158425595

Gene position: 4538945-4540594 (Clockwise)

Preceding gene: 158425594

Following gene: 158425597

Centisome position: 84.53

GC content: 68.55

Gene sequence:

>1650_bases
GTGCCTGCGGCGCTTTCCATCAGGGACAATCTTCGACACACCGGACTGGCCCTTGTGCCGCGCATGCTATCCATCGCATG
GTATAAAGATAACGCCCCGACAGAGAAGGCTGTTGCGACGTTGCCAACCCGTTTGAAGATGTCCCTCCGGCGGCACGGGG
TCATCGTGTCCGTATGCCTCGGCCTCATCGCGACCCTCGGCGTGCAGGCCGTTCTGCTGCTGGAGATCCGGCAGGACCGC
TGGACCAGCGCCATCCAGGCGGCGCAGAACGTGCTTCATACGCTGGACAGCGATGTCGACCGCAACCTCAATCTTCTCGA
CCTCTCCCTTCAGGGCGCGCAGGAGGCCACCACCCGCGTCGAGATCGCCAACCTCGACCCGGTGATCCGCAACCTCGTGC
TGTTCGATCGCGCCGGGAGTGCCGAATATCTCGGGGCCATGCTGGTGCTCTCCCCCAGCGGCGAGATCGTCTATGACGCC
AGCGAGGTGAAGCCCCGGAGCGGGAATTTCGCGGACCGGGACTATTTCCAGGTGCAGAAGGACAGCGCGCAGGAGCCCTA
TATCAGCGCGCCGTTCGTCGGGCGGCTGGGGGACGATAACCCCGGCATCGCCCTCAGCCGGCGGATCAGCAATCCGGACG
GCAGCTTTGACGGCGTGGTGATGGGGGCAATCAGCCTCAACTATTTCCGCGACCTCTTCTCGCGCATCAACATGGGCCGG
GCGGGCGAGATCGCCCTCGTGCGCAGCGACGGGCGCCTCGTCATGCGCTGGCCGTCCGGCGACACCCACGACCTGCTCAA
TGCCAGCATCTCGCGGTCGGGCCTCTTCCGGCACATCGCCGAAGGGCCGAGCGGTTCCTTCACCACCAGCGACGGCACCG
ACGGCGTCGAGCGGCATTACCTCTACGCCCCCGTCGGCCGTTTTCCGCTGACGCTGGTGGTGGGCTTCTCCGTGGACGAG
GTGCTCGGCCTCTGGCGGCGGCAGGCCCTCACCTTCGGCCTCATCGGATGCGTCATTGCCGGCGCCATCGTCCTTCTGGT
GCTGGCGCTGCAAGGCGCACTGCGGCGGGAGGAGAAGATGAGCGCGCGGTTCGAGAACCTCGCCACCACCGACTGGCTAA
CCGGGCTTCCCAACCGGCGCTCCTTCGACGAGCGCCTGATCGCCGCCGCCCGCAGCACCGCCCGCTCCGCGGCGCCGCTG
GCGCTGCTGATGATCGACGTGGACCGCTTCAAGGTGCTGAACGATCGTTTCGGCCATGGGCGCGGCGACGAGGTGCTCCG
CCAGATCAGCCAGGTGCTGAAGGCCTGCGCCCGCCGGCCGGACGACATGGTGGCGCGCTATGGCGGCGAGGAGTTCGCCG
CCGTGCTGCCTGGCACGGACGCCGCCGGCGCCGCCCGCGTGGCCGAGGCGATGCGGGCCGCGGTGGAGCACGCCTTCCCG
AGCCCCGACATGACCGTGACCGTGAGCATCGGGGCCGCCTCCGGTACGCTTGCCCCCGAGACGGAAACCCGGACCTTGCT
GGCCGCCGCCGATGCCGCGCTCTACGAGGCGAAAGCGCAGGGACGCAACCGGGTAGTCCTCGCATCCGGCACGGCGCCCG
TGACGGAGGCCCTGCCCCTGCTGCCGCCTTCACGCGTGCGCAGCCGCTGA

Upstream 100 bases:

>100_bases
TCACCGCCGTCCTCCGGATGCCGGCACTCACGCGGCCGCCGACTACACGTCCGAGGATCCCCGGACCGCTCAGGCGGTCT
GATCCATCGCAAGGCGGAGC

Downstream 100 bases:

>100_bases
GCCGTCGGTCGCGTCCGCCGGCCTCCCCCTTCTGCTCCGCAACCGCAAAGCAAAAGGGCCGCTCCGGTTCACGGAGCGGC
CCTCTGGTTCTGGTCCTGCG

Product: diguanylate cyclase

Products: NA

Alternate protein names: Bacteriophytochrome cph2 [H]

Number of amino acids: Translated: 549; Mature: 548

Protein sequence:

>549_residues
MPAALSIRDNLRHTGLALVPRMLSIAWYKDNAPTEKAVATLPTRLKMSLRRHGVIVSVCLGLIATLGVQAVLLLEIRQDR
WTSAIQAAQNVLHTLDSDVDRNLNLLDLSLQGAQEATTRVEIANLDPVIRNLVLFDRAGSAEYLGAMLVLSPSGEIVYDA
SEVKPRSGNFADRDYFQVQKDSAQEPYISAPFVGRLGDDNPGIALSRRISNPDGSFDGVVMGAISLNYFRDLFSRINMGR
AGEIALVRSDGRLVMRWPSGDTHDLLNASISRSGLFRHIAEGPSGSFTTSDGTDGVERHYLYAPVGRFPLTLVVGFSVDE
VLGLWRRQALTFGLIGCVIAGAIVLLVLALQGALRREEKMSARFENLATTDWLTGLPNRRSFDERLIAAARSTARSAAPL
ALLMIDVDRFKVLNDRFGHGRGDEVLRQISQVLKACARRPDDMVARYGGEEFAAVLPGTDAAGAARVAEAMRAAVEHAFP
SPDMTVTVSIGAASGTLAPETETRTLLAAADAALYEAKAQGRNRVVLASGTAPVTEALPLLPPSRVRSR

Sequences:

>Translated_549_residues
MPAALSIRDNLRHTGLALVPRMLSIAWYKDNAPTEKAVATLPTRLKMSLRRHGVIVSVCLGLIATLGVQAVLLLEIRQDR
WTSAIQAAQNVLHTLDSDVDRNLNLLDLSLQGAQEATTRVEIANLDPVIRNLVLFDRAGSAEYLGAMLVLSPSGEIVYDA
SEVKPRSGNFADRDYFQVQKDSAQEPYISAPFVGRLGDDNPGIALSRRISNPDGSFDGVVMGAISLNYFRDLFSRINMGR
AGEIALVRSDGRLVMRWPSGDTHDLLNASISRSGLFRHIAEGPSGSFTTSDGTDGVERHYLYAPVGRFPLTLVVGFSVDE
VLGLWRRQALTFGLIGCVIAGAIVLLVLALQGALRREEKMSARFENLATTDWLTGLPNRRSFDERLIAAARSTARSAAPL
ALLMIDVDRFKVLNDRFGHGRGDEVLRQISQVLKACARRPDDMVARYGGEEFAAVLPGTDAAGAARVAEAMRAAVEHAFP
SPDMTVTVSIGAASGTLAPETETRTLLAAADAALYEAKAQGRNRVVLASGTAPVTEALPLLPPSRVRSR
>Mature_548_residues
PAALSIRDNLRHTGLALVPRMLSIAWYKDNAPTEKAVATLPTRLKMSLRRHGVIVSVCLGLIATLGVQAVLLLEIRQDRW
TSAIQAAQNVLHTLDSDVDRNLNLLDLSLQGAQEATTRVEIANLDPVIRNLVLFDRAGSAEYLGAMLVLSPSGEIVYDAS
EVKPRSGNFADRDYFQVQKDSAQEPYISAPFVGRLGDDNPGIALSRRISNPDGSFDGVVMGAISLNYFRDLFSRINMGRA
GEIALVRSDGRLVMRWPSGDTHDLLNASISRSGLFRHIAEGPSGSFTTSDGTDGVERHYLYAPVGRFPLTLVVGFSVDEV
LGLWRRQALTFGLIGCVIAGAIVLLVLALQGALRREEKMSARFENLATTDWLTGLPNRRSFDERLIAAARSTARSAAPLA
LLMIDVDRFKVLNDRFGHGRGDEVLRQISQVLKACARRPDDMVARYGGEEFAAVLPGTDAAGAARVAEAMRAAVEHAFPS
PDMTVTVSIGAASGTLAPETETRTLLAAADAALYEAKAQGRNRVVLASGTAPVTEALPLLPPSRVRSR

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 GGDEF domains [H]

Homologues:

Organism=Escherichia coli, GI87081881, Length=185, Percent_Identity=36.7567567567568, Blast_Score=113, Evalue=4e-26,
Organism=Escherichia coli, GI145693134, Length=168, Percent_Identity=42.8571428571429, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI1787262, Length=174, Percent_Identity=37.3563218390805, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1786584, Length=173, Percent_Identity=35.8381502890173, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1787816, Length=163, Percent_Identity=35.5828220858896, Blast_Score=95, Evalue=9e-21,
Organism=Escherichia coli, GI87082007, Length=199, Percent_Identity=32.1608040201005, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1788085, Length=182, Percent_Identity=31.8681318681319, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1787056, Length=349, Percent_Identity=25.214899713467, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787802, Length=167, Percent_Identity=33.5329341317365, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1788381, Length=172, Percent_Identity=33.1395348837209, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI87081977, Length=158, Percent_Identity=31.0126582278481, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1787541, Length=177, Percent_Identity=31.638418079096, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI87081974, Length=184, Percent_Identity=27.7173913043478, Blast_Score=72, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR003018
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515 [H]

Pfam domain/function: PF00563 EAL; PF01590 GAF; PF00990 GGDEF; PF00360 Phytochrome [H]

EC number: NA

Molecular weight: Translated: 59317; Mature: 59185

Theoretical pI: Translated: 8.10; Mature: 8.10

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAALSIRDNLRHTGLALVPRMLSIAWYKDNAPTEKAVATLPTRLKMSLRRHGVIVSVCL
CCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHCCHHHHHHHHHCCHHHHHHH
GLIATLGVQAVLLLEIRQDRWTSAIQAAQNVLHTLDSDVDRNLNLLDLSLQGAQEATTRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHEE
EIANLDPVIRNLVLFDRAGSAEYLGAMLVLSPSGEIVYDASEVKPRSGNFADRDYFQVQK
EEECCCHHHHHHHHHCCCCCHHHHCEEEEECCCCCEEEEHHHCCCCCCCCCCCHHHHCCC
DSAQEPYISAPFVGRLGDDNPGIALSRRISNPDGSFDGVVMGAISLNYFRDLFSRINMGR
CCCCCCEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEHHHHHHHHHHHHHHCCCCC
AGEIALVRSDGRLVMRWPSGDTHDLLNASISRSGLFRHIAEGPSGSFTTSDGTDGVERHY
CCCEEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCE
LYAPVGRFPLTLVVGFSVDEVLGLWRRQALTFGLIGCVIAGAIVLLVLALQGALRREEKM
EEECCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SARFENLATTDWLTGLPNRRSFDERLIAAARSTARSAAPLALLMIDVDRFKVLNDRFGHG
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHCCCC
RGDEVLRQISQVLKACARRPDDMVARYGGEEFAAVLPGTDAAGAARVAEAMRAAVEHAFP
CHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCC
SPDMTVTVSIGAASGTLAPETETRTLLAAADAALYEAKAQGRNRVVLASGTAPVTEALPL
CCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHCCC
LPPSRVRSR
CCCHHHCCC
>Mature Secondary Structure 
PAALSIRDNLRHTGLALVPRMLSIAWYKDNAPTEKAVATLPTRLKMSLRRHGVIVSVCL
CCCCCHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHCCHHHHHHHHHCCHHHHHHH
GLIATLGVQAVLLLEIRQDRWTSAIQAAQNVLHTLDSDVDRNLNLLDLSLQGAQEATTRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHEE
EIANLDPVIRNLVLFDRAGSAEYLGAMLVLSPSGEIVYDASEVKPRSGNFADRDYFQVQK
EEECCCHHHHHHHHHCCCCCHHHHCEEEEECCCCCEEEEHHHCCCCCCCCCCCHHHHCCC
DSAQEPYISAPFVGRLGDDNPGIALSRRISNPDGSFDGVVMGAISLNYFRDLFSRINMGR
CCCCCCEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEHHHHHHHHHHHHHHCCCCC
AGEIALVRSDGRLVMRWPSGDTHDLLNASISRSGLFRHIAEGPSGSFTTSDGTDGVERHY
CCCEEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCE
LYAPVGRFPLTLVVGFSVDEVLGLWRRQALTFGLIGCVIAGAIVLLVLALQGALRREEKM
EEECCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SARFENLATTDWLTGLPNRRSFDERLIAAARSTARSAAPLALLMIDVDRFKVLNDRFGHG
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHCCCC
RGDEVLRQISQVLKACARRPDDMVARYGGEEFAAVLPGTDAAGAARVAEAMRAAVEHAFP
CHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCC
SPDMTVTVSIGAASGTLAPETETRTLLAAADAALYEAKAQGRNRVVLASGTAPVTEALPL
CCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHCCC
LPPSRVRSR
CCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10978170; 11063585 [H]