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The map label for this gene is moaE [H]

Identifier: 158425593

GI number: 158425593

Start: 4536718

End: 4537221

Strand: Direct

Name: moaE [H]

Synonym: AZC_3969

Alternate gene names: 158425593

Gene position: 4536718-4537221 (Clockwise)

Preceding gene: 158425592

Following gene: 158425594

Centisome position: 84.49

GC content: 71.43

Gene sequence:

>504_bases
GTGAGCGACTCCCCTCCCGCCGACGACCTGTTCGGCGTCCGCGTGCAGGCTGAGGATTTCGACGCCGCCGCAGAGATCGC
CGCTCTGGCGCAGGGCCGCACGGACATCGGCGCGGTGGTGACGTTCAGCGGCCTGTGCCGGGCGGACGTCAAGGACGGCC
TGCCGCTGGCCGCCCTGCATCTCGAACATTATCCCGGCATGGCAGAAGCCGAGATGGAGCGCATCCTCTACGAGGCCCGC
ACCCGCTGGCCGCTCTCCGGTGGCCGTGTCGTGCACCGCTTCGGGCGCATCGTGCCCGGCGAGAACATCGTGCTGGTCGT
CACCGCCTCGCCCCATCGCGGGGCGGCCTTCGCGGCGGCCGAATTCCTCATGGACTGGCTGAAGACCTCCGCCCCCTTCT
GGAAGAAGGAGGAACGCCCCGGCGCGGCCGATGACGGCGCCTGGGTCGAGGCCAAGGACGCGGACGACGACGCCGCCCTG
CGCTGGGGCTCGCCTTCGGCCTGA

Upstream 100 bases:

>100_bases
GGTGCGCGCCGCTCTCGACCGCAAGCATGTGAAGCCGGATGCGCCCCTCGGCGCGGCACGGGAGATCGCCTTCTTCCCGC
CCATGACCGGAGGCTGAGCG

Downstream 100 bases:

>100_bases
GTCGGGAGACGGCTCAGGAACGGCTTGCAGACCTGATGGTTCGTCAGGCGGAAAAATGCGGCGCCGCTCTAGATTTCGCT
GCCGCACAATGCAACGCATG

Product: molybdopterin converting factor subunit 2

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 167; Mature: 166

Protein sequence:

>167_residues
MSDSPPADDLFGVRVQAEDFDAAAEIAALAQGRTDIGAVVTFSGLCRADVKDGLPLAALHLEHYPGMAEAEMERILYEAR
TRWPLSGGRVVHRFGRIVPGENIVLVVTASPHRGAAFAAAEFLMDWLKTSAPFWKKEERPGAADDGAWVEAKDADDDAAL
RWGSPSA

Sequences:

>Translated_167_residues
MSDSPPADDLFGVRVQAEDFDAAAEIAALAQGRTDIGAVVTFSGLCRADVKDGLPLAALHLEHYPGMAEAEMERILYEAR
TRWPLSGGRVVHRFGRIVPGENIVLVVTASPHRGAAFAAAEFLMDWLKTSAPFWKKEERPGAADDGAWVEAKDADDDAAL
RWGSPSA
>Mature_166_residues
SDSPPADDLFGVRVQAEDFDAAAEIAALAQGRTDIGAVVTFSGLCRADVKDGLPLAALHLEHYPGMAEAEMERILYEART
RWPLSGGRVVHRFGRIVPGENIVLVVTASPHRGAAFAAAEFLMDWLKTSAPFWKKEERPGAADDGAWVEAKDADDDAALR
WGSPSA

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=101, Percent_Identity=34.6534653465347, Blast_Score=71, Evalue=5e-13,
Organism=Escherichia coli, GI1787003, Length=150, Percent_Identity=46.6666666666667, Blast_Score=125, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17509279, Length=113, Percent_Identity=35.3982300884956, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21356259, Length=133, Percent_Identity=34.5864661654135, Blast_Score=71, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 17974; Mature: 17843

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDSPPADDLFGVRVQAEDFDAAAEIAALAQGRTDIGAVVTFSGLCRADVKDGLPLAALH
CCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCCEEECCCHHHHHHHCCCCEEEEE
LEHYPGMAEAEMERILYEARTRWPLSGGRVVHRFGRIVPGENIVLVVTASPHRGAAFAAA
HHHCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHH
EFLMDWLKTSAPFWKKEERPGAADDGAWVEAKDADDDAALRWGSPSA
HHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCCEECCCCCCC
>Mature Secondary Structure 
SDSPPADDLFGVRVQAEDFDAAAEIAALAQGRTDIGAVVTFSGLCRADVKDGLPLAALH
CCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCCEEECCCHHHHHHHCCCCEEEEE
LEHYPGMAEAEMERILYEARTRWPLSGGRVVHRFGRIVPGENIVLVVTASPHRGAAFAAA
HHHCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHH
EFLMDWLKTSAPFWKKEERPGAADDGAWVEAKDADDDAALRWGSPSA
HHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]