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The map label for this gene is pgsA [H]

Identifier: 158425591

GI number: 158425591

Start: 4535834

End: 4536466

Strand: Direct

Name: pgsA [H]

Synonym: AZC_3967

Alternate gene names: 158425591

Gene position: 4535834-4536466 (Clockwise)

Preceding gene: 158425590

Following gene: 158425592

Centisome position: 84.47

GC content: 67.77

Gene sequence:

>633_bases
ATGGCCGAAGCAGTGACCCGCCCTTCTTCTCCCGCACCGGCGCGGAACCTCGCCTTCTCCGTGCCGAACATTCTCACCTA
TTCCCGCTGCGCGGCGGTGCCGCTGGTGGCCGCGTGCCTGTTCTGGGCCGACATCCTGCAAGGCGGCCTGTCGCTGCGCT
GGGTGGCGCTCGGCCTGTTCATCGCCGCCGCCGTGACGGATTTCTTCGACGGCTATCTCGCCCGCGCCTGGTCGCAGCAG
TCGGCCATCGGCCGCATGCTCGATCCCATCGCGGACAAGCTGCTGGTTTCCACCTGCCTCTTGATGCTGGCGTCGGACGG
CACCATCCGCGGCTGGTCGCTGTGGGCGGCCATCGTCATCCTGTGCCGCGAGATTCTCGTCTCGGGCCTGCGGGAATTCC
TCGCCGAGCTGCGCGTCAGCGTGCCGGTGTCCCGGCTCGCCAAATGGAAGACCACGCTCCAGCTCATCGCCGTCGGCTTC
CTGCTGGCGGGCGAGGCAGGCGACCGGCTGATCCATGGCGTGACCTATGCGGGCCTTGCCCTGCTGTGGATCTCCGCCGT
GCTCACCCTCTACACGGGCTATGACTATTTCCGGGCCGGCGGGCGCCATCTGGTGTCGGGAGACAATCGGTGA

Upstream 100 bases:

>100_bases
CTGCTTTCGCGCGCACAGTGGCTGCGATGGACGTAACGGCAGGCCTCGAGATTCGAGGCGCGCGGCGTCCCGTGGCAGAA
CGCACCGAGGCCCGTCCGGC

Downstream 100 bases:

>100_bases
AGGTGCTTTATTTCGCCTGGCTGCGCGAACGTGTGGGGGTTCCGGAGGAAGAGGTGGAGGTGCCCGCCGAGGTGCGCACC
GTCTCCGAACTCGCGGCCTT

Product: CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 210; Mature: 209

Protein sequence:

>210_residues
MAEAVTRPSSPAPARNLAFSVPNILTYSRCAAVPLVAACLFWADILQGGLSLRWVALGLFIAAAVTDFFDGYLARAWSQQ
SAIGRMLDPIADKLLVSTCLLMLASDGTIRGWSLWAAIVILCREILVSGLREFLAELRVSVPVSRLAKWKTTLQLIAVGF
LLAGEAGDRLIHGVTYAGLALLWISAVLTLYTGYDYFRAGGRHLVSGDNR

Sequences:

>Translated_210_residues
MAEAVTRPSSPAPARNLAFSVPNILTYSRCAAVPLVAACLFWADILQGGLSLRWVALGLFIAAAVTDFFDGYLARAWSQQ
SAIGRMLDPIADKLLVSTCLLMLASDGTIRGWSLWAAIVILCREILVSGLREFLAELRVSVPVSRLAKWKTTLQLIAVGF
LLAGEAGDRLIHGVTYAGLALLWISAVLTLYTGYDYFRAGGRHLVSGDNR
>Mature_209_residues
AEAVTRPSSPAPARNLAFSVPNILTYSRCAAVPLVAACLFWADILQGGLSLRWVALGLFIAAAVTDFFDGYLARAWSQQS
AIGRMLDPIADKLLVSTCLLMLASDGTIRGWSLWAAIVILCREILVSGLREFLAELRVSVPVSRLAKWKTTLQLIAVGFL
LAGEAGDRLIHGVTYAGLALLWISAVLTLYTGYDYFRAGGRHLVSGDNR

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=195, Percent_Identity=36.9230769230769, Blast_Score=108, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6320059, Length=179, Percent_Identity=31.8435754189944, Blast_Score=78, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 22713; Mature: 22582

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEAVTRPSSPAPARNLAFSVPNILTYSRCAAVPLVAACLFWADILQGGLSLRWVALGLF
CCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
IAAAVTDFFDGYLARAWSQQSAIGRMLDPIADKLLVSTCLLMLASDGTIRGWSLWAAIVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
LCREILVSGLREFLAELRVSVPVSRLAKWKTTLQLIAVGFLLAGEAGDRLIHGVTYAGLA
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
LLWISAVLTLYTGYDYFRAGGRHLVSGDNR
HHHHHHHHHHHHCHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
AEAVTRPSSPAPARNLAFSVPNILTYSRCAAVPLVAACLFWADILQGGLSLRWVALGLF
CCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
IAAAVTDFFDGYLARAWSQQSAIGRMLDPIADKLLVSTCLLMLASDGTIRGWSLWAAIVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
LCREILVSGLREFLAELRVSVPVSRLAKWKTTLQLIAVGFLLAGEAGDRLIHGVTYAGLA
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
LLWISAVLTLYTGYDYFRAGGRHLVSGDNR
HHHHHHHHHHHHCHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA