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The map label for this gene is cobG [H]

Identifier: 158425560

GI number: 158425560

Start: 4501978

End: 4503327

Strand: Direct

Name: cobG [H]

Synonym: AZC_3936

Alternate gene names: 158425560

Gene position: 4501978-4503327 (Clockwise)

Preceding gene: 158425559

Following gene: 158425561

Centisome position: 83.84

GC content: 74.15

Gene sequence:

>1350_bases
GTGACCATGTCGACATCTCCTAGGCCCCCCTCCCGCCGGGGCATCTGCCCGGCGCTCTCAGCCCCCATGGCCACCGGCGA
CGGCCTCCTCGTGCGGCTCGTGCCGGCGGAGGGCTGGCTCACGCTCGCCCAGATGCGCGGGCTGGCCTCCGCCGCCCGCG
CGTATGGCAATGGCATCATCGAGATCACGGCCAAGGGCAGCGTGCAGATCCGGGGTCTGACCGAGGACAGCGTCGGCCCG
CTCAATGCCGCCGTGGGCCGGCTCGGCATCACGCCACGCACCGGCCTGCCCGTCGACGTCTCGCCCCTTTCCGGCATCGA
CGCCACCGAGGCGGTCGATGCCCGGCTGATGGCGGCCCGGCTGCATGAGATGGCGGCGGACCTCGTGCCCCGGCTCGGCG
CCAAGGTCTCCGTGGTGGTGGATGGCGGCGGGGCGCTGAGCCTCGATGCCTTCAAGACCGACGTGCGGCTGGTGGCCCGT
CCCGGCAAGGGCGAGAAGATGTGGGACGTTTCGCTGGCGGGGGATGCGGCGCGCGCGCTCCCCTTCGGCAGCGTGCGGGG
GCGCGATGCGCCGGACCTCGTGCGCGGCCTGCTGGAGCGCCTCGCGGCGCTTGGCCCCTCAGCCCGTATGGCGGACGCCC
TGCCCCCGGCCACCGATGCTCCGCCCCGCCCCATGCGTGAAACGAGCCCCATCGGCCTCTTCGCGCTGACGGACGGCTCG
ACAGCCTGCGGCATCGGCCTGCCCTTCGGCGCGCTGCACGCGGATGATCTCGACGCCCTCATCGCAGCCGCAGAAGCGGC
GGGCGCACGCGACCTGCGGCCGGCGCCCGACCATGGCCTCCTCGCCACCGGCCTGTCGGCCGAGGACGTGGACACCTTCC
GCACGGCGGCGGCGCAGATCGGCTGCCTCGTCCTGGCGGATGATCCCCGCCGCTTTGTCGCCGCCTGCCCCGGCGCACCG
GCCTGCGCCTCCGCTGACATTCCCGCCCGCGCCATCGCAGCGGAGGTGGCGCAGGTGCTTGGCAAGGCGCTGGACGGCTC
GCTCCAGGTGCACATCTCGGCCTGCAGCAAGGGGTGCGCGCATCCTGCGCCGGCCAACCTCACCCTCGTCGGCCTGCCCG
CCGACGCCATGGACAATCGGGTGGCGCTCGTGCGAGAGGGCAGAGCGGGGGATGCAACCCGGCCGCAGATCACGGCCGAG
GCGCTTCTTCCCACGCTCGCCCGCCTCGCCGGCGCGCTCGACGCGGCCCACACGCCCGGCGCGCGCATGGTCGAGACGCT
GGCGGCCCTGCCGTCCTCGTCGCTGGAGCCGTTGCTGTTGTCACCCGCCGTGCTGGAGTCCACCCCGTGA

Upstream 100 bases:

>100_bases
CCCGCAATAGCCCTGCGGAGCGTTTCAGCCATCCCACCGCGCGGCCCCCGTACGCGGCTCATGACCATTCCTCAGGCCGC
ACCGCCCGGCGGCAGGGCAG

Downstream 100 bases:

>100_bases
GCCCCTCGCCTCTCGATTATGAGCGCGACGGCACGGCCATCTACGAACGCTCCTTCGCCATCATCCGCGCCGAGGCCGAC
CTTTCCCGCTTCTCGGACGA

Product: cobalamin synthesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MTMSTSPRPPSRRGICPALSAPMATGDGLLVRLVPAEGWLTLAQMRGLASAARAYGNGIIEITAKGSVQIRGLTEDSVGP
LNAAVGRLGITPRTGLPVDVSPLSGIDATEAVDARLMAARLHEMAADLVPRLGAKVSVVVDGGGALSLDAFKTDVRLVAR
PGKGEKMWDVSLAGDAARALPFGSVRGRDAPDLVRGLLERLAALGPSARMADALPPATDAPPRPMRETSPIGLFALTDGS
TACGIGLPFGALHADDLDALIAAAEAAGARDLRPAPDHGLLATGLSAEDVDTFRTAAAQIGCLVLADDPRRFVAACPGAP
ACASADIPARAIAAEVAQVLGKALDGSLQVHISACSKGCAHPAPANLTLVGLPADAMDNRVALVREGRAGDATRPQITAE
ALLPTLARLAGALDAAHTPGARMVETLAALPSSSLEPLLLSPAVLESTP

Sequences:

>Translated_449_residues
MTMSTSPRPPSRRGICPALSAPMATGDGLLVRLVPAEGWLTLAQMRGLASAARAYGNGIIEITAKGSVQIRGLTEDSVGP
LNAAVGRLGITPRTGLPVDVSPLSGIDATEAVDARLMAARLHEMAADLVPRLGAKVSVVVDGGGALSLDAFKTDVRLVAR
PGKGEKMWDVSLAGDAARALPFGSVRGRDAPDLVRGLLERLAALGPSARMADALPPATDAPPRPMRETSPIGLFALTDGS
TACGIGLPFGALHADDLDALIAAAEAAGARDLRPAPDHGLLATGLSAEDVDTFRTAAAQIGCLVLADDPRRFVAACPGAP
ACASADIPARAIAAEVAQVLGKALDGSLQVHISACSKGCAHPAPANLTLVGLPADAMDNRVALVREGRAGDATRPQITAE
ALLPTLARLAGALDAAHTPGARMVETLAALPSSSLEPLLLSPAVLESTP
>Mature_448_residues
TMSTSPRPPSRRGICPALSAPMATGDGLLVRLVPAEGWLTLAQMRGLASAARAYGNGIIEITAKGSVQIRGLTEDSVGPL
NAAVGRLGITPRTGLPVDVSPLSGIDATEAVDARLMAARLHEMAADLVPRLGAKVSVVVDGGGALSLDAFKTDVRLVARP
GKGEKMWDVSLAGDAARALPFGSVRGRDAPDLVRGLLERLAALGPSARMADALPPATDAPPRPMRETSPIGLFALTDGST
ACGIGLPFGALHADDLDALIAAAEAAGARDLRPAPDHGLLATGLSAEDVDTFRTAAAQIGCLVLADDPRRFVAACPGAPA
CASADIPARAIAAEVAQVLGKALDGSLQVHISACSKGCAHPAPANLTLVGLPADAMDNRVALVREGRAGDATRPQITAEA
LLPTLARLAGALDAAHTPGARMVETLAALPSSSLEPLLLSPAVLESTP

Specific function: Catalyzes the elimination of C-20 in precorrin-3A to form precorrin-3B [H]

COG id: COG0155

COG function: function code P; Sulfite reductase, beta subunit (hemoprotein)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012798
- InterPro:   IPR005117
- InterPro:   IPR006066 [H]

Pfam domain/function: PF03460 NIR_SIR_ferr [H]

EC number: =1.14.13.83 [H]

Molecular weight: Translated: 45503; Mature: 45372

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMSTSPRPPSRRGICPALSAPMATGDGLLVRLVPAEGWLTLAQMRGLASAARAYGNGII
CCCCCCCCCCCCCCCCHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEE
EITAKGSVQIRGLTEDSVGPLNAAVGRLGITPRTGLPVDVSPLSGIDATEAVDARLMAAR
EEEECCCEEEEECCCCCCCCHHHHHHHCCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHH
LHEMAADLVPRLGAKVSVVVDGGGALSLDAFKTDVRLVARPGKGEKMWDVSLAGDAARAL
HHHHHHHHHHHCCCEEEEEEECCCEEEEHHHCCCEEEEECCCCCCEEEEEEECCCHHHHC
PFGSVRGRDAPDLVRGLLERLAALGPSARMADALPPATDAPPRPMRETSPIGLFALTDGS
CCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCC
TACGIGLPFGALHADDLDALIAAAEAAGARDLRPAPDHGLLATGLSAEDVDTFRTAAAQI
CEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHH
GCLVLADDPRRFVAACPGAPACASADIPARAIAAEVAQVLGKALDGSLQVHISACSKGCA
CEEEEECCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCC
HPAPANLTLVGLPADAMDNRVALVREGRAGDATRPQITAEALLPTLARLAGALDAAHTPG
CCCCCCEEEEECCHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCH
ARMVETLAALPSSSLEPLLLSPAVLESTP
HHHHHHHHHCCCCCCCCCEECCHHHCCCC
>Mature Secondary Structure 
TMSTSPRPPSRRGICPALSAPMATGDGLLVRLVPAEGWLTLAQMRGLASAARAYGNGII
CCCCCCCCCCCCCCCHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEE
EITAKGSVQIRGLTEDSVGPLNAAVGRLGITPRTGLPVDVSPLSGIDATEAVDARLMAAR
EEEECCCEEEEECCCCCCCCHHHHHHHCCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHH
LHEMAADLVPRLGAKVSVVVDGGGALSLDAFKTDVRLVARPGKGEKMWDVSLAGDAARAL
HHHHHHHHHHHCCCEEEEEEECCCEEEEHHHCCCEEEEECCCCCCEEEEEEECCCHHHHC
PFGSVRGRDAPDLVRGLLERLAALGPSARMADALPPATDAPPRPMRETSPIGLFALTDGS
CCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCC
TACGIGLPFGALHADDLDALIAAAEAAGARDLRPAPDHGLLATGLSAEDVDTFRTAAAQI
CEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHH
GCLVLADDPRRFVAACPGAPACASADIPARAIAAEVAQVLGKALDGSLQVHISACSKGCA
CEEEEECCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCC
HPAPANLTLVGLPADAMDNRVALVREGRAGDATRPQITAEALLPTLARLAGALDAAHTPG
CCCCCCEEEEECCHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCH
ARMVETLAALPSSSLEPLLLSPAVLESTP
HHHHHHHHHCCCCCCCCCEECCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2211521 [H]