Click here to switch to the map view.

The map label for this gene is pleC [H]

Identifier: 158425532

GI number: 158425532

Start: 4464454

End: 4465512

Strand: Direct

Name: pleC [H]

Synonym: AZC_3908

Alternate gene names: 158425532

Gene position: 4464454-4465512 (Clockwise)

Preceding gene: 158425526

Following gene: 158425539

Centisome position: 83.14

GC content: 73.94

Gene sequence:

>1059_bases
ATGACGCAGGCCCCGATGGATCGCGCCGCCGGCGCCGCCCCGCACAGCGGGCGCGCAGCCGAAGGCCGCGGATTCGACGA
GGCCCTGGCCGAGGCGCGCCGCTCCGTGCGCTGGCTGGCCGGCGCGCTGGCGGTTTTCGTCGTCGCCTTGCTGCTGGCGC
GGCTGCGCGCCTCGCTGCTGTGGCTCGCCGCCGCCCCGCTGCTGTTCGCCGCCATCGAGCTGTTCACCCTCGGCCGCACG
CTGGGGCGCCTGTCGGCCGCCCGCCGCGCGGAGGCTCACGCGCAGGCCGCCCGCACCGCCGCCGCCGAGGCGGAGAATCA
GGCCAAGTCCCGCTTCCTCGCCGAGATGAGCCACGAGCTGCGCACCCCGCTCAACGCGGTCATCGGCTTTTCCGAAGTGA
TGGCGCAGGAGGTGCTCGGCCCGCACGCCAACGCCGCCTATCGCGATTATGCGCAGGACATCCACGCCTCGGGCCGCCAT
CTGCTGGCGCTGGCCGATGACATCCTCGATCTGGCCCGCATCGAGACCGGCCACCGGCAGGTGCTGGAGACGGCGGTGAA
CCTCGGCGCCCTGGCGCAGGACTGCGCGCACATGATGCGGCTCGGCGCGGCGGAGCGGGACATCACGCTCATCGTCACCC
TCAATGCCCGCCCCCGCCTGTGGGCGGACGAGCGCGCGGTGCGCCAGATGGTGCTGAACCTGATGGCCAACGCGGTGAAG
TTCACGCCCGCCGGCGGCACCGTCGAGTTGTTCGTGGACAGCGATGCGGAGGGCGCGCCCTTCTGCGCGGTGGAAGACAA
CGGGCCAGGGCTGGCGGACGCCGAGCTGCCCCTCGCCCTCTCGGCCCACCACCGGGAAAGCCGGCTCGATCCGGCGAGCG
GCCAGGGCGCAGGCCTCGGCCTTGCCATCGTGCGGGCGCTGGCGCAGATGCACGAGGCGCGGCTGGATCTTACGGAACGG
GCCACGGGCGGCACGCGGGCCACCCTTTCCTTTCCCGCCTCCCGCGCGCTCGCGGCGGCGGAGGGAACCACCCCCACGCC
CCTGCTGGCGGCGGAATAG

Upstream 100 bases:

>100_bases
TGGCGTTAACCATTCATCAACCCTGCTCAAGCAGGAGTCGGATGGAAGATCGGAGTCTGGCCAAAGCGCGCCACGACCCC
GGCGCAGAAGGTTCGCGCGC

Downstream 100 bases:

>100_bases
CCTCAAGTCCGGCCTTGCCGCCCAGATGGATGCATCTGGGCGGACCGCCTGTTACGCCTTGTTGGAGACGCCGCCGTCGC
TGAAGGTGCCCATGCCGCGA

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MTQAPMDRAAGAAPHSGRAAEGRGFDEALAEARRSVRWLAGALAVFVVALLLARLRASLLWLAAAPLLFAAIELFTLGRT
LGRLSAARRAEAHAQAARTAAAEAENQAKSRFLAEMSHELRTPLNAVIGFSEVMAQEVLGPHANAAYRDYAQDIHASGRH
LLALADDILDLARIETGHRQVLETAVNLGALAQDCAHMMRLGAAERDITLIVTLNARPRLWADERAVRQMVLNLMANAVK
FTPAGGTVELFVDSDAEGAPFCAVEDNGPGLADAELPLALSAHHRESRLDPASGQGAGLGLAIVRALAQMHEARLDLTER
ATGGTRATLSFPASRALAAAEGTTPTPLLAAE

Sequences:

>Translated_352_residues
MTQAPMDRAAGAAPHSGRAAEGRGFDEALAEARRSVRWLAGALAVFVVALLLARLRASLLWLAAAPLLFAAIELFTLGRT
LGRLSAARRAEAHAQAARTAAAEAENQAKSRFLAEMSHELRTPLNAVIGFSEVMAQEVLGPHANAAYRDYAQDIHASGRH
LLALADDILDLARIETGHRQVLETAVNLGALAQDCAHMMRLGAAERDITLIVTLNARPRLWADERAVRQMVLNLMANAVK
FTPAGGTVELFVDSDAEGAPFCAVEDNGPGLADAELPLALSAHHRESRLDPASGQGAGLGLAIVRALAQMHEARLDLTER
ATGGTRATLSFPASRALAAAEGTTPTPLLAAE
>Mature_351_residues
TQAPMDRAAGAAPHSGRAAEGRGFDEALAEARRSVRWLAGALAVFVVALLLARLRASLLWLAAAPLLFAAIELFTLGRTL
GRLSAARRAEAHAQAARTAAAEAENQAKSRFLAEMSHELRTPLNAVIGFSEVMAQEVLGPHANAAYRDYAQDIHASGRHL
LALADDILDLARIETGHRQVLETAVNLGALAQDCAHMMRLGAAERDITLIVTLNARPRLWADERAVRQMVLNLMANAVKF
TPAGGTVELFVDSDAEGAPFCAVEDNGPGLADAELPLALSAHHRESRLDPASGQGAGLGLAIVRALAQMHEARLDLTERA
TGGTRATLSFPASRALAAAEGTTPTPLLAAE

Specific function: Member of the two-component regulatory system involved in the regulation of polar organelle development. PleC functions as a membrane-associated protein kinase that transfers phosphate to the response regulator pleD, leading to its activation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=253, Percent_Identity=31.2252964426877, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1786600, Length=232, Percent_Identity=29.3103448275862, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI48994928, Length=238, Percent_Identity=29.8319327731092, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI87081816, Length=258, Percent_Identity=34.1085271317829, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1789149, Length=231, Percent_Identity=31.1688311688312, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1786912, Length=272, Percent_Identity=28.3088235294118, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790861, Length=246, Percent_Identity=29.6747967479675, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1788393, Length=238, Percent_Identity=27.3109243697479, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI145693157, Length=242, Percent_Identity=28.9256198347107, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788279, Length=205, Percent_Identity=25.8536585365854, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1786783, Length=231, Percent_Identity=24.6753246753247, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 37164; Mature: 37033

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQAPMDRAAGAAPHSGRAAEGRGFDEALAEARRSVRWLAGALAVFVVALLLARLRASLL
CCCCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WLAAAPLLFAAIELFTLGRTLGRLSAARRAEAHAQAARTAAAEAENQAKSRFLAEMSHEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTPLNAVIGFSEVMAQEVLGPHANAAYRDYAQDIHASGRHLLALADDILDLARIETGHRQ
HCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
VLETAVNLGALAQDCAHMMRLGAAERDITLIVTLNARPRLWADERAVRQMVLNLMANAVK
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHE
FTPAGGTVELFVDSDAEGAPFCAVEDNGPGLADAELPLALSAHHRESRLDPASGQGAGLG
ECCCCCEEEEEEECCCCCCCEEEEECCCCCCCCCCCCCHHHCHHHHHCCCCCCCCCCCHH
LAIVRALAQMHEARLDLTERATGGTRATLSFPASRALAAAEGTTPTPLLAAE
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
TQAPMDRAAGAAPHSGRAAEGRGFDEALAEARRSVRWLAGALAVFVVALLLARLRASLL
CCCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WLAAAPLLFAAIELFTLGRTLGRLSAARRAEAHAQAARTAAAEAENQAKSRFLAEMSHEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTPLNAVIGFSEVMAQEVLGPHANAAYRDYAQDIHASGRHLLALADDILDLARIETGHRQ
HCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
VLETAVNLGALAQDCAHMMRLGAAERDITLIVTLNARPRLWADERAVRQMVLNLMANAVK
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHE
FTPAGGTVELFVDSDAEGAPFCAVEDNGPGLADAELPLALSAHHRESRLDPASGQGAGLG
ECCCCCEEEEEEECCCCCCCEEEEECCCCCCCCCCCCCHHHCHHHHHCCCCCCCCCCCHH
LAIVRALAQMHEARLDLTERATGGTRATLSFPASRALAAAEGTTPTPLLAAE
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8421698; 11259647 [H]