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The map label for this gene is lysR [C]

Identifier: 158425427

GI number: 158425427

Start: 4356423

End: 4357316

Strand: Direct

Name: lysR [C]

Synonym: AZC_3803

Alternate gene names: 158425427

Gene position: 4356423-4357316 (Clockwise)

Preceding gene: 158425425

Following gene: 158425444

Centisome position: 81.13

GC content: 61.41

Gene sequence:

>894_bases
ATGCTCGATTACGCCCACCTCACTGCACTCGCGGCCGTGATCCGAACCGGCAGCTTTGAGCGGGCAGCACAGCAGCTCAA
CGTCACGCCTTCAGCAGTCTCGCAGAGGATCAAGCTGCTTGAGGAACGGCTTGGGGTGGTGCTGGTGGTCCGAGATCAGC
CCTGCACAGCAACCGAGGTAGGTCAGCGCCTGTGCCAGCACGTCGAGCAGGTTGCCCTACTTGAGAGCTCCTTGAAGGGG
AGCCTTCCGGGCCTTCAGGCTGAGAGCCTGCCAGTGACCCTGCGGATTGCGGTGAATGCCGACAGTCTCGCGACTTGGTT
CATTCCTGCCATGGCCAAGACGGAAGGGTATCTATTCGACTTGGTGCTGGATGATCAGGACCACAGCGCAGAATGGCTGC
GGCGCGGCGAGGTTGTGGCGGCAGTGACGGGGCACGACACACCGATCCAGGGATGTGACTGCCATCCTCTCGGAGCCTTG
CGCTATGTTGCAACTGCAAGCCCGGAGTATTGCGGCCGATGGTTTACCGACGGCTTTAACGAACTTACGGCGGCTCGCGC
CCCGTGTCTGATCTTCAACCAGAAAGATCGGCTCCAGGTCGAATGGCTGCGGCAGGTGCTCGGAGCTGATGTTCATCCCC
CGCTGCACTTGCTCCCCTCCTCCCAAGCTTTTGTGGATGCAGCCCTGGCTGGGATCGGGTGGGGCATGAACCCGGAGCCA
CTCGTGATCGACCATCTTCGCACCGGGAGGCTCGTTGCGCTCAAGCCGGACAAGTCTTTGGACGTTCCGCTGTTCTGGCA
GCAGAGCCGTATTGTGAGCCGAGTGATGGGCAATGTGACCCGCGCTGTCGTGAGCGAGGCCAGAACCATGCTGGCCTTCG
CGATCGGGACATGA

Upstream 100 bases:

>100_bases
ATGGTCATGTCGAACTCCGACTAAGGATCGACATGAGGTACGCCAGGGCTCATGATTAGGGCACTTAAACCTTCTCAGCC
CGCATTAGAGTTTCTAATCT

Downstream 100 bases:

>100_bases
GAGTTCGATAGGCAGGATGCTTTGCCAACCTGAAGGGGGTGCTGGGCCAAATCCCGCCCTGACGCACCTAGGATACCATT
TTGGGCTACCACTGGATACC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MLDYAHLTALAAVIRTGSFERAAQQLNVTPSAVSQRIKLLEERLGVVLVVRDQPCTATEVGQRLCQHVEQVALLESSLKG
SLPGLQAESLPVTLRIAVNADSLATWFIPAMAKTEGYLFDLVLDDQDHSAEWLRRGEVVAAVTGHDTPIQGCDCHPLGAL
RYVATASPEYCGRWFTDGFNELTAARAPCLIFNQKDRLQVEWLRQVLGADVHPPLHLLPSSQAFVDAALAGIGWGMNPEP
LVIDHLRTGRLVALKPDKSLDVPLFWQQSRIVSRVMGNVTRAVVSEARTMLAFAIGT

Sequences:

>Translated_297_residues
MLDYAHLTALAAVIRTGSFERAAQQLNVTPSAVSQRIKLLEERLGVVLVVRDQPCTATEVGQRLCQHVEQVALLESSLKG
SLPGLQAESLPVTLRIAVNADSLATWFIPAMAKTEGYLFDLVLDDQDHSAEWLRRGEVVAAVTGHDTPIQGCDCHPLGAL
RYVATASPEYCGRWFTDGFNELTAARAPCLIFNQKDRLQVEWLRQVLGADVHPPLHLLPSSQAFVDAALAGIGWGMNPEP
LVIDHLRTGRLVALKPDKSLDVPLFWQQSRIVSRVMGNVTRAVVSEARTMLAFAIGT
>Mature_297_residues
MLDYAHLTALAAVIRTGSFERAAQQLNVTPSAVSQRIKLLEERLGVVLVVRDQPCTATEVGQRLCQHVEQVALLESSLKG
SLPGLQAESLPVTLRIAVNADSLATWFIPAMAKTEGYLFDLVLDDQDHSAEWLRRGEVVAAVTGHDTPIQGCDCHPLGAL
RYVATASPEYCGRWFTDGFNELTAARAPCLIFNQKDRLQVEWLRQVLGADVHPPLHLLPSSQAFVDAALAGIGWGMNPEP
LVIDHLRTGRLVALKPDKSLDVPLFWQQSRIVSRVMGNVTRAVVSEARTMLAFAIGT

Specific function: Specific Inhibitor Of Chromosomal Initiation Of Replication In VItro. Binds The Three 13-Mers In The Origin (Oric) To Block Initiation Of Replication. [C]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789283, Length=295, Percent_Identity=38.6440677966102, Blast_Score=167, Evalue=9e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR017685
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32477; Mature: 32477

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDYAHLTALAAVIRTGSFERAAQQLNVTPSAVSQRIKLLEERLGVVLVVRDQPCTATEV
CCCHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCHHHH
GQRLCQHVEQVALLESSLKGSLPGLQAESLPVTLRIAVNADSLATWFIPAMAKTEGYLFD
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCEEEE
LVLDDQDHSAEWLRRGEVVAAVTGHDTPIQGCDCHPLGALRYVATASPEYCGRWFTDGFN
EEECCCCCHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHCCHH
ELTAARAPCLIFNQKDRLQVEWLRQVLGADVHPPLHLLPSSQAFVDAALAGIGWGMNPEP
HHHHHCCCEEEECCCCCHHHHHHHHHHCCCCCCCCEECCCCHHHHHHHHHHCCCCCCCCC
LVIDHLRTGRLVALKPDKSLDVPLFWQQSRIVSRVMGNVTRAVVSEARTMLAFAIGT
EEEEECCCCEEEEECCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHEECC
>Mature Secondary Structure
MLDYAHLTALAAVIRTGSFERAAQQLNVTPSAVSQRIKLLEERLGVVLVVRDQPCTATEV
CCCHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCHHHH
GQRLCQHVEQVALLESSLKGSLPGLQAESLPVTLRIAVNADSLATWFIPAMAKTEGYLFD
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCEEEE
LVLDDQDHSAEWLRRGEVVAAVTGHDTPIQGCDCHPLGALRYVATASPEYCGRWFTDGFN
EEECCCCCHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHCCHH
ELTAARAPCLIFNQKDRLQVEWLRQVLGADVHPPLHLLPSSQAFVDAALAGIGWGMNPEP
HHHHHCCCEEEECCCCCHHHHHHHHHHCCCCCCCCEECCCCHHHHHHHHHHCCCCCCCCC
LVIDHLRTGRLVALKPDKSLDVPLFWQQSRIVSRVMGNVTRAVVSEARTMLAFAIGT
EEEEECCCCEEEEECCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]