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The map label for this gene is yjiA [H]

Identifier: 158425424

GI number: 158425424

Start: 4353221

End: 4354210

Strand: Reverse

Name: yjiA [H]

Synonym: AZC_3800

Alternate gene names: 158425424

Gene position: 4354210-4353221 (Counterclockwise)

Preceding gene: 158425426

Following gene: 158425423

Centisome position: 81.09

GC content: 63.84

Gene sequence:

>990_bases
ATGAGCAAAATATCGGCCACAATCCTCACTGGTTTTCTGGGGGGCGGCAAGACCACACTCCTGAATATCCTTTTGGAGGC
TTCTCCTGGCGAGCGGGCCCTCGTTATCGTTAATGAATACGGCGAGGTCGGCATTGACGGAAAGCTAGTCGTCGAGACAC
AGGACGAGGTGGTCGAGTTGAATAACGGCTGCGTCTGCTGCACGGTGCGCGGTGATCTCATCGCTGCCATGCAGGGGGTG
CTCGCTTCCGGCCGGCCAATCGACCGGATTATCATCGAGACATCGGGCCTTGCAGATCCAGCGCCGGTCATCCAGTCCTT
CATGCTGGATGAGGTGCTGCGTGAGCGGCTGGCTCTCGATGCTATCGTCACCGTAGTGGATGCGCGCCACATCACCGACC
AGATCGCTCTCGACGAGGCGCGCGAGCAAATCTGCTTCGCCGACGTGCTCTTGCTCAACAAGATCGACTTGGTGGACGAG
GCGAGCCTTGCCGCAACGCAGGACATGCTGCGACGCCTGAACCCGCTGGCCCGCATCATCCGCACGCAGGCCTGCGCCGT
CCCCCGTGACGCCGTGCTCGATGTTCGCGCCTTCGACCTTCGGAACGCGCTTGCCGTCGATCCCGAAATTCTCGCGGACC
ACGCCCATGAGCACGACGCGAGCATTGCATACGTTGCGCTCCGCGAGGCCACACAGCTCGATCCGGCGGCCTTCAACATC
TGGATCAACCGGTTGGTACAGGCGGCCGGCAAGGATCTGTTCCGCATCAAGGGTGTGCTCGCCTTCGCCGAGGAGCCGCG
GCGCTATGTGTTCCACGGCGTGCACATGACGCTGGAAGGCCGCCCTGGGCGCGCCTGGCGTGCGGATGAGGCGCGCTGCA
GCGAGATCGTCTTCATCGGCCGCAACCTCGATGAGGCGGCGTTACGCCGGAGCCTCGACGCCTGCCGGGACACGCGCGCA
CCGTCCGAGCGCACCGCACGCGCCGGCTGA

Upstream 100 bases:

>100_bases
CTTTGGCAGAATCTGCAGCCTCTCCCGTATTGCCCTGATGCTCTGCTTGACTTTGAATTATCTCGAATGTGACACGAATA
TTTGAGGCTAGGCGAAATCG

Downstream 100 bases:

>100_bases
CAGGCAGGGCAACGCGCGTCGTCGGAACGCAAAGCAAACAAAATTAAAACGACCTTCCCAGAGGAGAATTATATGCCTCC
GCTTGTTGCTGCCATGGTCA

Product: cobalamin synthesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MSKISATILTGFLGGGKTTLLNILLEASPGERALVIVNEYGEVGIDGKLVVETQDEVVELNNGCVCCTVRGDLIAAMQGV
LASGRPIDRIIIETSGLADPAPVIQSFMLDEVLRERLALDAIVTVVDARHITDQIALDEAREQICFADVLLLNKIDLVDE
ASLAATQDMLRRLNPLARIIRTQACAVPRDAVLDVRAFDLRNALAVDPEILADHAHEHDASIAYVALREATQLDPAAFNI
WINRLVQAAGKDLFRIKGVLAFAEEPRRYVFHGVHMTLEGRPGRAWRADEARCSEIVFIGRNLDEAALRRSLDACRDTRA
PSERTARAG

Sequences:

>Translated_329_residues
MSKISATILTGFLGGGKTTLLNILLEASPGERALVIVNEYGEVGIDGKLVVETQDEVVELNNGCVCCTVRGDLIAAMQGV
LASGRPIDRIIIETSGLADPAPVIQSFMLDEVLRERLALDAIVTVVDARHITDQIALDEAREQICFADVLLLNKIDLVDE
ASLAATQDMLRRLNPLARIIRTQACAVPRDAVLDVRAFDLRNALAVDPEILADHAHEHDASIAYVALREATQLDPAAFNI
WINRLVQAAGKDLFRIKGVLAFAEEPRRYVFHGVHMTLEGRPGRAWRADEARCSEIVFIGRNLDEAALRRSLDACRDTRA
PSERTARAG
>Mature_328_residues
SKISATILTGFLGGGKTTLLNILLEASPGERALVIVNEYGEVGIDGKLVVETQDEVVELNNGCVCCTVRGDLIAAMQGVL
ASGRPIDRIIIETSGLADPAPVIQSFMLDEVLRERLALDAIVTVVDARHITDQIALDEAREQICFADVLLLNKIDLVDEA
SLAATQDMLRRLNPLARIIRTQACAVPRDAVLDVRAFDLRNALAVDPEILADHAHEHDASIAYVALREATQLDPAAFNIW
INRLVQAAGKDLFRIKGVLAFAEEPRRYVFHGVHMTLEGRPGRAWRADEARCSEIVFIGRNLDEAALRRSLDACRDTRAP
SERTARAG

Specific function: Binds GTP. May function as GTP-dependent regulator [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI148727351, Length=333, Percent_Identity=33.3333333333333, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI146231952, Length=333, Percent_Identity=33.6336336336336, Blast_Score=175, Evalue=4e-44,
Organism=Homo sapiens, GI126722884, Length=333, Percent_Identity=33.033033033033, Blast_Score=175, Evalue=5e-44,
Organism=Homo sapiens, GI33469141, Length=333, Percent_Identity=32.7327327327327, Blast_Score=175, Evalue=6e-44,
Organism=Homo sapiens, GI223941779, Length=331, Percent_Identity=31.4199395770393, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI223941776, Length=323, Percent_Identity=32.1981424148607, Blast_Score=160, Evalue=1e-39,
Organism=Homo sapiens, GI119120938, Length=325, Percent_Identity=30.1538461538462, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI310124603, Length=221, Percent_Identity=26.6968325791855, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI310124599, Length=188, Percent_Identity=29.2553191489362, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI169184311, Length=183, Percent_Identity=27.3224043715847, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI87082430, Length=322, Percent_Identity=33.5403726708075, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1788499, Length=225, Percent_Identity=31.5555555555556, Blast_Score=100, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6324356, Length=364, Percent_Identity=27.4725274725275, Blast_Score=118, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 35961; Mature: 35830

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKISATILTGFLGGGKTTLLNILLEASPGERALVIVNEYGEVGIDGKLVVETQDEVVEL
CCCHHHHHHHHHCCCCHHHHHHHHEECCCCCEEEEEEECCCCCCCCCEEEEECCHHEEEE
NNGCVCCTVRGDLIAAMQGVLASGRPIDRIIIETSGLADPAPVIQSFMLDEVLRERLALD
CCCEEEEEECCHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
AIVTVVDARHITDQIALDEAREQICFADVLLLNKIDLVDEASLAATQDMLRRLNPLARII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
RTQACAVPRDAVLDVRAFDLRNALAVDPEILADHAHEHDASIAYVALREATQLDPAAFNI
HHHHHCCCCHHHEEEHHHHHCCHHCCCHHHHHHCCCCCCCCEEEEEEHHHHCCCHHHHHH
WINRLVQAAGKDLFRIKGVLAFAEEPRRYVFHGVHMTLEGRPGRAWRADEARCSEIVFIG
HHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEEEEEEEEECCCCCCCCCCCCCCCEEEEEE
RNLDEAALRRSLDACRDTRAPSERTARAG
CCCCHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SKISATILTGFLGGGKTTLLNILLEASPGERALVIVNEYGEVGIDGKLVVETQDEVVEL
CCHHHHHHHHHCCCCHHHHHHHHEECCCCCEEEEEEECCCCCCCCCEEEEECCHHEEEE
NNGCVCCTVRGDLIAAMQGVLASGRPIDRIIIETSGLADPAPVIQSFMLDEVLRERLALD
CCCEEEEEECCHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
AIVTVVDARHITDQIALDEAREQICFADVLLLNKIDLVDEASLAATQDMLRRLNPLARII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
RTQACAVPRDAVLDVRAFDLRNALAVDPEILADHAHEHDASIAYVALREATQLDPAAFNI
HHHHHCCCCHHHEEEHHHHHCCHHCCCHHHHHHCCCCCCCCEEEEEEHHHHCCCHHHHHH
WINRLVQAAGKDLFRIKGVLAFAEEPRRYVFHGVHMTLEGRPGRAWRADEARCSEIVFIG
HHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEEEEEEEEECCCCCCCCCCCCCCCEEEEEE
RNLDEAALRRSLDACRDTRAPSERTARAG
CCCCHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 1650347 [H]