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The map label for this gene is aroB [H]

Identifier: 158425289

GI number: 158425289

Start: 4212986

End: 4214473

Strand: Reverse

Name: aroB [H]

Synonym: AZC_3665

Alternate gene names: 158425289

Gene position: 4214473-4212986 (Counterclockwise)

Preceding gene: 158425290

Following gene: 158425288

Centisome position: 78.49

GC content: 69.56

Gene sequence:

>1488_bases
ATGGCCGGCGAGGCCCCGGTCGCGGTCATCGACATCGGATCCAATTCCGTCCGCCTCGTGGTCTATGAGGCGGTGACCCG
TGCTCCGGTTCCCCTGTTCAACGAGAAGGCCCTGTGCGGGCTCGGCCGGGACGTGCTGTCCACCGGCCGGCTCGCGGAGG
ATGCGGTGCAGCGGGCCTTCTCGGCCCTGCGCCGGTTCCGCGGCCTGTGCGACGCCATGGGGGTGGGCAAGCTCTATGCG
CTCGCCACCGCCGCCGCCCGCGATGCCCAGAACGGCCCGGCCTTCATCGCCGAGTGCGAGGCCATCTGCGGCGTCTCCAT
CGAGATCCTGTCGGGTCGCCGCGAGGCGGAACTGGCCGCTTATGGCGTCATCTCCGGCATCCATGATCCGGACGGTGTCG
CCGGCGATCTCGGCGGCGGCTCTCTGGAACTCGTGGACATCAAGCGCGAGGTGGTGGGCAACGGCATAACCCTGCCCATC
GGCGGCCTCGCCTTGCAGGACCGCTCGTCCAAGTCGCTGAACAAGGCGGAGAAGATCGTCCGAGACGCCATGCGCGATGC
CCCCGTGCTCTCGGAAGTGGCGGGGCGCACCTTCTATGCGGTGGGCGGCACCTGGCGCGCGCTCGCGCGCCTGCACATGT
TCCAGCGGGGCTATCCGCTGCATGTGATGCATGGCTACCGCCTGCCGGCGAAGGAAGTGCTCGACTTCACGCGCATCGTC
CACCGGGCCGAGCCCGAGGCGCTGGCTCATATCGAGGCGGTGTCCAGCGCCCGCCGCCCGCTGCTCGCCTATGGCGCGGT
GGTGCTGGAGAATCTGGTGCGCACGGGCCGTCCGGCGGACGTCGTCATCTCCGCGCTGGGCGTCCGCGAGGGTCTGCTCT
ACGCGCTCCTCGACGCCGAGACGCGCCGGCACGATCCGCTGCTCATCGAGGCACAGGACTTCAACATCCTGCGCTCGCGC
TCGCCGCAGCATGGCGAGGAGCTCGCCACCTGGACCGGCAATTTCTTCGCCTCCAGCCCGGTGCTGGAGGAGAGCACGGA
GGAACGGCGCCTGCGCGAGGCGGCGTGCCTTCTCTCCGACATCGCCTGGCGGGCGCATCCCGACTATCGCGGCGAGCAGA
GCCTCAACGTCATCGCCCATGCGGCGCTGGTGGGCATCGACCATCCCGGCCGCGCCTTCCTCGCCCTGTCGGTCTATTAC
CGGCACATGGGCCTCGGCGAGGACGAGTATGCGCCGCGCCTCCTTGAGCTCGTGACCTCCGGCATGCTCGACCGGGCGCG
CATCCTCGGTGCCGCCATGCGGGTGGCCTATGTGATGTCGGCCGCCATGCCCGGCATCCTGCCGCGGGTGCCGCTCATCG
CCGACGAGACCCACCTGAAGCTCACCGTTCCGTCCGATCTCGCGAGCCTCGTGAACGACCGGGTGCAGAACCGCCTGAAG
CAACTGGCACGCCTCATCGGCCGCGAGCCCTCCATCGTCATGAGCTGA

Upstream 100 bases:

>100_bases
CCGAGCTTGTCAGGACGTGGAAAGTCTCTCAAGGATTCTTCGCCGCGCAGTCTCCTCGTCCGCCGTTCGGGAGGATGACC
ACAGGGGCCTTTCCACCCTG

Downstream 100 bases:

>100_bases
GGGCGGGAACCTTGAGCCAGGGTGTGGCGATGCTCCTGCATCCGCACCCCGGCGCGTTCTCGCCCGGGGGCTCACGAGCA
AGAGGCGCCGATGCCCCACA

Product: Ppx/GppA phosphatase

Products: NA

Alternate protein names: 3-dehydroquinate synthase; Unknown phosphatase [H]

Number of amino acids: Translated: 495; Mature: 494

Protein sequence:

>495_residues
MAGEAPVAVIDIGSNSVRLVVYEAVTRAPVPLFNEKALCGLGRDVLSTGRLAEDAVQRAFSALRRFRGLCDAMGVGKLYA
LATAAARDAQNGPAFIAECEAICGVSIEILSGRREAELAAYGVISGIHDPDGVAGDLGGGSLELVDIKREVVGNGITLPI
GGLALQDRSSKSLNKAEKIVRDAMRDAPVLSEVAGRTFYAVGGTWRALARLHMFQRGYPLHVMHGYRLPAKEVLDFTRIV
HRAEPEALAHIEAVSSARRPLLAYGAVVLENLVRTGRPADVVISALGVREGLLYALLDAETRRHDPLLIEAQDFNILRSR
SPQHGEELATWTGNFFASSPVLEESTEERRLREAACLLSDIAWRAHPDYRGEQSLNVIAHAALVGIDHPGRAFLALSVYY
RHMGLGEDEYAPRLLELVTSGMLDRARILGAAMRVAYVMSAAMPGILPRVPLIADETHLKLTVPSDLASLVNDRVQNRLK
QLARLIGREPSIVMS

Sequences:

>Translated_495_residues
MAGEAPVAVIDIGSNSVRLVVYEAVTRAPVPLFNEKALCGLGRDVLSTGRLAEDAVQRAFSALRRFRGLCDAMGVGKLYA
LATAAARDAQNGPAFIAECEAICGVSIEILSGRREAELAAYGVISGIHDPDGVAGDLGGGSLELVDIKREVVGNGITLPI
GGLALQDRSSKSLNKAEKIVRDAMRDAPVLSEVAGRTFYAVGGTWRALARLHMFQRGYPLHVMHGYRLPAKEVLDFTRIV
HRAEPEALAHIEAVSSARRPLLAYGAVVLENLVRTGRPADVVISALGVREGLLYALLDAETRRHDPLLIEAQDFNILRSR
SPQHGEELATWTGNFFASSPVLEESTEERRLREAACLLSDIAWRAHPDYRGEQSLNVIAHAALVGIDHPGRAFLALSVYY
RHMGLGEDEYAPRLLELVTSGMLDRARILGAAMRVAYVMSAAMPGILPRVPLIADETHLKLTVPSDLASLVNDRVQNRLK
QLARLIGREPSIVMS
>Mature_494_residues
AGEAPVAVIDIGSNSVRLVVYEAVTRAPVPLFNEKALCGLGRDVLSTGRLAEDAVQRAFSALRRFRGLCDAMGVGKLYAL
ATAAARDAQNGPAFIAECEAICGVSIEILSGRREAELAAYGVISGIHDPDGVAGDLGGGSLELVDIKREVVGNGITLPIG
GLALQDRSSKSLNKAEKIVRDAMRDAPVLSEVAGRTFYAVGGTWRALARLHMFQRGYPLHVMHGYRLPAKEVLDFTRIVH
RAEPEALAHIEAVSSARRPLLAYGAVVLENLVRTGRPADVVISALGVREGLLYALLDAETRRHDPLLIEAQDFNILRSRS
PQHGEELATWTGNFFASSPVLEESTEERRLREAACLLSDIAWRAHPDYRGEQSLNVIAHAALVGIDHPGRAFLALSVYYR
HMGLGEDEYAPRLLELVTSGMLDRARILGAAMRVAYVMSAAMPGILPRVPLIADETHLKLTVPSDLASLVNDRVQNRLKQ
LARLIGREPSIVMS

Specific function: Conversion Of Pppgpp To Ppgpp. Guanosine Pentaphosphate (Pppgpp) Is A Cytoplasmic Signaling Molecule Which Together With Ppgpp Controls The "Stringent Response", An Adaptive Process That Allows Bacteria To Respond To Amino Acid Starvation, Resulting In T

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the gppA/ppx family [H]

Homologues:

Organism=Escherichia coli, GI48994966, Length=301, Percent_Identity=25.9136212624585, Blast_Score=69, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6321185, Length=457, Percent_Identity=25.8205689277899, Blast_Score=96, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002658
- InterPro:   IPR016037
- InterPro:   IPR003695 [H]

Pfam domain/function: PF01761 DHQ_synthase; PF02541 Ppx-GppA [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 53600; Mature: 53469

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGEAPVAVIDIGSNSVRLVVYEAVTRAPVPLFNEKALCGLGRDVLSTGRLAEDAVQRAF
CCCCCCEEEEEECCCCEEEEEEEHHHCCCCCCCCCCHHHHCCHHHHHCCCHHHHHHHHHH
SALRRFRGLCDAMGVGKLYALATAAARDAQNGPAFIAECEAICGVSIEILSGRREAELAA
HHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCEEEEECCCCHHHHHH
YGVISGIHDPDGVAGDLGGGSLELVDIKREVVGNGITLPIGGLALQDRSSKSLNKAEKIV
HHHHCCCCCCCCCCCCCCCCCEEEEEEHHHHHCCCCEECCCCEEECCCCCHHHHHHHHHH
RDAMRDAPVLSEVAGRTFYAVGGTWRALARLHMFQRGYPLHVMHGYRLPAKEVLDFTRIV
HHHHHCCHHHHHHCCCEEEEECHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHH
HRAEPEALAHIEAVSSARRPLLAYGAVVLENLVRTGRPADVVISALGVREGLLYALLDAE
HHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC
TRRHDPLLIEAQDFNILRSRSPQHGEELATWTGNFFASSPVLEESTEERRLREAACLLSD
CCCCCCEEEEECCCHHHHCCCCCCCHHHHHHCCCCCCCCCCHHCCHHHHHHHHHHHHHHH
IAWRAHPDYRGEQSLNVIAHAALVGIDHPGRAFLALSVYYRHMGLGEDEYAPRLLELVTS
HHHHCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
GMLDRARILGAAMRVAYVMSAAMPGILPRVPLIADETHLKLTVPSDLASLVNDRVQNRLK
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCEEEEECCHHHHHHHHHHHHHHHH
QLARLIGREPSIVMS
HHHHHHCCCCCEECC
>Mature Secondary Structure 
AGEAPVAVIDIGSNSVRLVVYEAVTRAPVPLFNEKALCGLGRDVLSTGRLAEDAVQRAF
CCCCCEEEEEECCCCEEEEEEEHHHCCCCCCCCCCHHHHCCHHHHHCCCHHHHHHHHHH
SALRRFRGLCDAMGVGKLYALATAAARDAQNGPAFIAECEAICGVSIEILSGRREAELAA
HHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCEEEEECCCCHHHHHH
YGVISGIHDPDGVAGDLGGGSLELVDIKREVVGNGITLPIGGLALQDRSSKSLNKAEKIV
HHHHCCCCCCCCCCCCCCCCCEEEEEEHHHHHCCCCEECCCCEEECCCCCHHHHHHHHHH
RDAMRDAPVLSEVAGRTFYAVGGTWRALARLHMFQRGYPLHVMHGYRLPAKEVLDFTRIV
HHHHHCCHHHHHHCCCEEEEECHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHH
HRAEPEALAHIEAVSSARRPLLAYGAVVLENLVRTGRPADVVISALGVREGLLYALLDAE
HHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC
TRRHDPLLIEAQDFNILRSRSPQHGEELATWTGNFFASSPVLEESTEERRLREAACLLSD
CCCCCCEEEEECCCHHHHCCCCCCCHHHHHHCCCCCCCCCCHHCCHHHHHHHHHHHHHHH
IAWRAHPDYRGEQSLNVIAHAALVGIDHPGRAFLALSVYYRHMGLGEDEYAPRLLELVTS
HHHHCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
GMLDRARILGAAMRVAYVMSAAMPGILPRVPLIADETHLKLTVPSDLASLVNDRVQNRLK
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCEEEEECCHHHHHHHHHHHHHHHH
QLARLIGREPSIVMS
HHHHHHCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11889109 [H]