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The map label for this gene is oxlT [H]

Identifier: 158425257

GI number: 158425257

Start: 4170476

End: 4171804

Strand: Reverse

Name: oxlT [H]

Synonym: AZC_3633

Alternate gene names: 158425257

Gene position: 4171804-4170476 (Counterclockwise)

Preceding gene: 158425258

Following gene: 158425250

Centisome position: 77.69

GC content: 65.54

Gene sequence:

>1329_bases
GTGTGGGAAGGGAAGGAAATGTCGTCAGTCCAAACCGCAAGCCAGGGGCCCGTCGGAGGGCGTTGGCTGCAGCTGCTCAT
CGGCGTGGTCTGCATGTCGATGATCGCCAACCTGCAATATGGCTGGACGCTCTTCGTCGAGCCGATCAATGACAAGTATC
ACTGGGGTCGTCCGGCGATTCAGGTGGCGTTCACCATCTTCGTGCTCACCGAGACCTGGCTGGTCCCGATCGAGGGCTGG
TTCGTCGACAAGTTCGGTCCTCGCATCGTCGTCTTCATCGGCGGCATCCTGTGCGCCGCCGCCTGGGCCATGAACTCGGT
CGCGAGCTCTCTGGCGCTCCTCTACGTCTCCGCGGCCATCGGCGGCATCGGCGCCGGCGCGGTGTACGGCACCTGCGTGG
GTGCGGCGCTCAAGTGGTTCCCGGATCGTCGCGGTCTCGCCGCCGGCCTCACCGCCGCGGGCTTCGGTGCCGGCTCGGCC
ATCACTATCGTCCCCATCGCGGACATGATCCACAATGCGGGCTATGAGCAGACCTTCCTCGTGTTCGGCCTGCTGCAGGG
CGGCGTGGTGCTGCTGCTCTCGCTGCTGCTCCAGAGCCCGAAGGAAGGCCAACTGCCGAAGACGGTCTCCAAGGGGATCG
TGCAGAGCCGCCGCAACTACGGCCCCGGCGAGATGGCCAAGGCTCCGGTGTTCTGGGTCATGTACCTGATGTTCGTGCTG
GTGGCCGCGGGCGGCCTGATGGCCACGGCGCAGCTCGGCTCCATCGCCAAGGACTTCCACATCGGCGATGTGCCGGTGAG
CCTGATGGGCATCACCATGCCGGCGCTGACCTTCGCGCTGTCCATCGACCGCGTGCTGAACGGCCTCACCCGCCCGTTCT
TCGGCTGGGTGTCGGATAACATCGGCCGCGAGAACACCATGTTCATCGCCTTCGCCCTCGAGGCGGTCGGCGTTCTGGCC
CTCGCCAAGTTCGGCTCCAACCCGGTGGCCTTCGTTCTGCTCACCGGCCTCGTCTTCTTCGCCTGGGGCGAGATCTACTC
GCTCTTCCCGGCCACCTGCGGCGATACCTTCGGCTCGAAGTTCGCCACCACCAATGCCGGCCTGCTCTACACGGCCAAGG
GCACGGCCTCGCTGGTGGTCCCCTTCGCCAGCATCGCCGTGGCGCAGATGGGCAACTGGGACATGGTGTTCCTCGTCACC
GCGGCGGTGAACGCCATTGCGGCCCTGATGGCGCTGTTCGTTCTGAAGCCCATGCGCTCCCGCTTCGTGGCCCAGGCCAA
GATCGAATCGGAAGAGATCGGCAAGGTTCAGGCGAAGATCGCCAACTGA

Upstream 100 bases:

>100_bases
ACAGTGACGGTACGCAAGCCGACCCGACGCCAAGCGGGCACGGCCTAGAAGAACGGCGACCGTCACGGGCCTTCATCGAC
CAGTCTTCGATGACACCAAC

Downstream 100 bases:

>100_bases
TGACGAGAGGCGGGGCCGAGCCCCGCCGGACATCGAGACTGCGGTCCCCGGTCCGTCCGGGGGCCGTTTTCATTTGGGAA
AGGGAAAACGTCGTCTCAGA

Product: oxalate/formate antiporter

Products: NA

Alternate protein names: OFA; Oxalate:formate antiport protein; Oxalate:formate exchange protein [H]

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MWEGKEMSSVQTASQGPVGGRWLQLLIGVVCMSMIANLQYGWTLFVEPINDKYHWGRPAIQVAFTIFVLTETWLVPIEGW
FVDKFGPRIVVFIGGILCAAAWAMNSVASSLALLYVSAAIGGIGAGAVYGTCVGAALKWFPDRRGLAAGLTAAGFGAGSA
ITIVPIADMIHNAGYEQTFLVFGLLQGGVVLLLSLLLQSPKEGQLPKTVSKGIVQSRRNYGPGEMAKAPVFWVMYLMFVL
VAAGGLMATAQLGSIAKDFHIGDVPVSLMGITMPALTFALSIDRVLNGLTRPFFGWVSDNIGRENTMFIAFALEAVGVLA
LAKFGSNPVAFVLLTGLVFFAWGEIYSLFPATCGDTFGSKFATTNAGLLYTAKGTASLVVPFASIAVAQMGNWDMVFLVT
AAVNAIAALMALFVLKPMRSRFVAQAKIESEEIGKVQAKIAN

Sequences:

>Translated_442_residues
MWEGKEMSSVQTASQGPVGGRWLQLLIGVVCMSMIANLQYGWTLFVEPINDKYHWGRPAIQVAFTIFVLTETWLVPIEGW
FVDKFGPRIVVFIGGILCAAAWAMNSVASSLALLYVSAAIGGIGAGAVYGTCVGAALKWFPDRRGLAAGLTAAGFGAGSA
ITIVPIADMIHNAGYEQTFLVFGLLQGGVVLLLSLLLQSPKEGQLPKTVSKGIVQSRRNYGPGEMAKAPVFWVMYLMFVL
VAAGGLMATAQLGSIAKDFHIGDVPVSLMGITMPALTFALSIDRVLNGLTRPFFGWVSDNIGRENTMFIAFALEAVGVLA
LAKFGSNPVAFVLLTGLVFFAWGEIYSLFPATCGDTFGSKFATTNAGLLYTAKGTASLVVPFASIAVAQMGNWDMVFLVT
AAVNAIAALMALFVLKPMRSRFVAQAKIESEEIGKVQAKIAN
>Mature_442_residues
MWEGKEMSSVQTASQGPVGGRWLQLLIGVVCMSMIANLQYGWTLFVEPINDKYHWGRPAIQVAFTIFVLTETWLVPIEGW
FVDKFGPRIVVFIGGILCAAAWAMNSVASSLALLYVSAAIGGIGAGAVYGTCVGAALKWFPDRRGLAAGLTAAGFGAGSA
ITIVPIADMIHNAGYEQTFLVFGLLQGGVVLLLSLLLQSPKEGQLPKTVSKGIVQSRRNYGPGEMAKAPVFWVMYLMFVL
VAAGGLMATAQLGSIAKDFHIGDVPVSLMGITMPALTFALSIDRVLNGLTRPFFGWVSDNIGRENTMFIAFALEAVGVLA
LAKFGSNPVAFVLLTGLVFFAWGEIYSLFPATCGDTFGSKFATTNAGLLYTAKGTASLVVPFASIAVAQMGNWDMVFLVT
AAVNAIAALMALFVLKPMRSRFVAQAKIESEEIGKVQAKIAN

Specific function: Anion transporter that carries out the exchange of divalent oxalate with monovalent formate, the product of oxalate decarboxylation, at the plasma membrane, and in doing so catalyzes the vectorial portion of a proton-motive metabolic cycle that drives ATP

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. OFA (TC 2.A.1.11) family [H]

Homologues:

Organism=Escherichia coli, GI1789969, Length=387, Percent_Identity=26.8733850129199, Blast_Score=105, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI193209150, Length=392, Percent_Identity=20.6632653061225, Blast_Score=65, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR004741 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46979; Mature: 46979

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWEGKEMSSVQTASQGPVGGRWLQLLIGVVCMSMIANLQYGWTLFVEPINDKYHWGRPAI
CCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHH
QVAFTIFVLTETWLVPIEGWFVDKFGPRIVVFIGGILCAAAWAMNSVASSLALLYVSAAI
HHHHHHHHHHHHHEEEECCEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGIGAGAVYGTCVGAALKWFPDRRGLAAGLTAAGFGAGSAITIVPIADMIHNAGYEQTFL
CCCCCHHHHHHHHHHHHHHCCCCCCCHHCCHHHCCCCCCEEEEEEHHHHHHCCCCCHHHH
VFGLLQGGVVLLLSLLLQSPKEGQLPKTVSKGIVQSRRNYGPGEMAKAPVFWVMYLMFVL
HHHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHH
VAAGGLMATAQLGSIAKDFHIGDVPVSLMGITMPALTFALSIDRVLNGLTRPFFGWVSDN
HHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
IGRENTMFIAFALEAVGVLALAKFGSNPVAFVLLTGLVFFAWGEIYSLFPATCGDTFGSK
CCCCCCEEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHCCCHHCCC
FATTNAGLLYTAKGTASLVVPFASIAVAQMGNWDMVFLVTAAVNAIAALMALFVLKPMRS
CEECCCCEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RFVAQAKIESEEIGKVQAKIAN
HHHHHHHCCHHHHHHHHHEECC
>Mature Secondary Structure
MWEGKEMSSVQTASQGPVGGRWLQLLIGVVCMSMIANLQYGWTLFVEPINDKYHWGRPAI
CCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHH
QVAFTIFVLTETWLVPIEGWFVDKFGPRIVVFIGGILCAAAWAMNSVASSLALLYVSAAI
HHHHHHHHHHHHHEEEECCEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGIGAGAVYGTCVGAALKWFPDRRGLAAGLTAAGFGAGSAITIVPIADMIHNAGYEQTFL
CCCCCHHHHHHHHHHHHHHCCCCCCCHHCCHHHCCCCCCEEEEEEHHHHHHCCCCCHHHH
VFGLLQGGVVLLLSLLLQSPKEGQLPKTVSKGIVQSRRNYGPGEMAKAPVFWVMYLMFVL
HHHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHH
VAAGGLMATAQLGSIAKDFHIGDVPVSLMGITMPALTFALSIDRVLNGLTRPFFGWVSDN
HHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
IGRENTMFIAFALEAVGVLALAKFGSNPVAFVLLTGLVFFAWGEIYSLFPATCGDTFGSK
CCCCCCEEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHCCCHHCCC
FATTNAGLLYTAKGTASLVVPFASIAVAQMGNWDMVFLVTAAVNAIAALMALFVLKPMRS
CEECCCCEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RFVAQAKIESEEIGKVQAKIAN
HHHHHHHCCHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8636101; 9651403; 11919184; 11113128; 11274108; 11500368 [H]