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The map label for this gene is sufS [H]

Identifier: 158425236

GI number: 158425236

Start: 4140311

End: 4141603

Strand: Reverse

Name: sufS [H]

Synonym: AZC_3612

Alternate gene names: 158425236

Gene position: 4141603-4140311 (Counterclockwise)

Preceding gene: 158425237

Following gene: 158425235

Centisome position: 77.13

GC content: 66.36

Gene sequence:

>1293_bases
ATGGTCTCAAGCCCGGCGGGGCGGCTCCGGATAAGGACATTGCCGATGACCAAGGGCCATCCCGCCGTGTTGGACGGCGC
CTATGACGTGGAGAAGGTGCGCGCGGACTTTCCCGCGCTCGCCCTCGAAGTCCACGGCCACCCGCTCACCTATCTGGACA
ATGCGGCTTCCGCCCAGAAGCCGGTGCAGGTGCTGGAGCGCATGCGCCACGCCTATGAGGCGGAATATTCCAACGTCCAT
CGCGGCCTGCACTATCTCGCCAACGCCATGACGGAAGCCTTCGAGGGCGCCCGCGAGAGCGCCCGGCGCTTCCTCAATGC
GGCTTCGCAGGACGAGATCATCTTCACCCGCTCCGGCACCGGCTCCATCAATCTGGTGGCGAACTCGCTCGGGCAGTCCA
TCGGGGAGGGGGATGAGATCATCCTCTCCATCATGGAGCACCACTCCAACATCGTGCCCTGGCACTTCCTGCGCGAGCGC
AAGGGCGCGGTCATCAAGTGGGCGCCGGTGCGCGAGGACGGGTCGTTCGACTTCGAGGCGTTCGAGCAGTTGCTGACGCC
GCGCACCAAGATCGTCGCCATCACCCACATGTCCAACGTGCTCGGCACGGTGACGCCCATCAAGGAGATCGTCCGCGCCG
CCCATGCGGTGGGCGCAAAGGTGGTGGTGGACGGCTGCCAGGCCTCCGTGCACCTGCCCGTGGACGTGCGCGACCTCGAT
GTCGATTTCTATGCCGTCACCGGTCACAAGCTCTATGGCCCCACCGGCATCGGCCTGCTCTATGGCAAGCGGGCGCTGCT
GGCCGAAATGCCGCCCTATGAGGGCGGCGGCGAGATGATCCGCGAGGTGGAGGAAGGCCGCGTCACCTATGCCGAGCCGC
CCCACCGCTTCGAGGCGGGCACGCCGGCCATCGTGCAGGCCATCGGCCTCGGCGCGGCGCTGGACTATATGGACCTCATC
GGCCGCGAGGCGATTGCCGCCCATGAACATGACCTCTCGGTCTATGCCCACCAGCAGCTCGGCGCGCTGAACAGCCTGCG
CATCATCGGCACCGCGAAGGACAAGGGCGCCATCGTCGCCTTCGAGATGAAGGGCGCCCACCCCCACGATGTGGCGACCG
TCATCGACCGGTACGGTGTTGCCGTGCGCGCGGGCACCCATTGCGCTCAGCCGCTTTTGGCCCGATATGGCACCACAGCG
ACGTGCCGCGCATCCTTCGCGCTCTACAATACGCGCAGTGACGTGGACCGCCTCGTGGCGGCCCTCCTCAAGGCGCAGGA
TTTGTTCTCATGA

Upstream 100 bases:

>100_bases
GCTCGTGTCGCGGCCTGCGCAGGCGTTATCCCGCGCGGTGCTGCCATCTGGAACGTACCGCGTTCGTATTTCCTGAGCTA
AGGCGGAGTGGCCCGCTTCG

Downstream 100 bases:

>100_bases
CCGATACTGTGGCCAACGATACGCCCAACGCGCCCGCGATTTCCTCCGGGATCCCGGAGGCGGAACTGACGCGCCTGACC
GACGAGATCGTCGGCGCGCT

Product: cysteine desulphurase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MVSSPAGRLRIRTLPMTKGHPAVLDGAYDVEKVRADFPALALEVHGHPLTYLDNAASAQKPVQVLERMRHAYEAEYSNVH
RGLHYLANAMTEAFEGARESARRFLNAASQDEIIFTRSGTGSINLVANSLGQSIGEGDEIILSIMEHHSNIVPWHFLRER
KGAVIKWAPVREDGSFDFEAFEQLLTPRTKIVAITHMSNVLGTVTPIKEIVRAAHAVGAKVVVDGCQASVHLPVDVRDLD
VDFYAVTGHKLYGPTGIGLLYGKRALLAEMPPYEGGGEMIREVEEGRVTYAEPPHRFEAGTPAIVQAIGLGAALDYMDLI
GREAIAAHEHDLSVYAHQQLGALNSLRIIGTAKDKGAIVAFEMKGAHPHDVATVIDRYGVAVRAGTHCAQPLLARYGTTA
TCRASFALYNTRSDVDRLVAALLKAQDLFS

Sequences:

>Translated_430_residues
MVSSPAGRLRIRTLPMTKGHPAVLDGAYDVEKVRADFPALALEVHGHPLTYLDNAASAQKPVQVLERMRHAYEAEYSNVH
RGLHYLANAMTEAFEGARESARRFLNAASQDEIIFTRSGTGSINLVANSLGQSIGEGDEIILSIMEHHSNIVPWHFLRER
KGAVIKWAPVREDGSFDFEAFEQLLTPRTKIVAITHMSNVLGTVTPIKEIVRAAHAVGAKVVVDGCQASVHLPVDVRDLD
VDFYAVTGHKLYGPTGIGLLYGKRALLAEMPPYEGGGEMIREVEEGRVTYAEPPHRFEAGTPAIVQAIGLGAALDYMDLI
GREAIAAHEHDLSVYAHQQLGALNSLRIIGTAKDKGAIVAFEMKGAHPHDVATVIDRYGVAVRAGTHCAQPLLARYGTTA
TCRASFALYNTRSDVDRLVAALLKAQDLFS
>Mature_430_residues
MVSSPAGRLRIRTLPMTKGHPAVLDGAYDVEKVRADFPALALEVHGHPLTYLDNAASAQKPVQVLERMRHAYEAEYSNVH
RGLHYLANAMTEAFEGARESARRFLNAASQDEIIFTRSGTGSINLVANSLGQSIGEGDEIILSIMEHHSNIVPWHFLRER
KGAVIKWAPVREDGSFDFEAFEQLLTPRTKIVAITHMSNVLGTVTPIKEIVRAAHAVGAKVVVDGCQASVHLPVDVRDLD
VDFYAVTGHKLYGPTGIGLLYGKRALLAEMPPYEGGGEMIREVEEGRVTYAEPPHRFEAGTPAIVQAIGLGAALDYMDLI
GREAIAAHEHDLSVYAHQQLGALNSLRIIGTAKDKGAIVAFEMKGAHPHDVATVIDRYGVAVRAGTHCAQPLLARYGTTA
TCRASFALYNTRSDVDRLVAALLKAQDLFS

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=265, Percent_Identity=27.1698113207547, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI156713448, Length=427, Percent_Identity=27.4004683840749, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1787970, Length=405, Percent_Identity=50.8641975308642, Blast_Score=399, Evalue=1e-112,
Organism=Escherichia coli, GI1789175, Length=403, Percent_Identity=41.6873449131514, Blast_Score=310, Evalue=1e-85,
Organism=Escherichia coli, GI48994898, Length=217, Percent_Identity=30.8755760368664, Blast_Score=87, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI25143064, Length=276, Percent_Identity=30.4347826086957, Blast_Score=105, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI193211090, Length=400, Percent_Identity=26, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6319831, Length=243, Percent_Identity=27.9835390946502, Blast_Score=103, Evalue=4e-23,
Organism=Drosophila melanogaster, GI20129463, Length=301, Percent_Identity=28.2392026578073, Blast_Score=114, Evalue=9e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 46752; Mature: 46752

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSSPAGRLRIRTLPMTKGHPAVLDGAYDVEKVRADFPALALEVHGHPLTYLDNAASAQK
CCCCCCCCEEEEEECCCCCCCCEECCCHHHHHHHCCCCEEEEEECCCCEEECCCCCCHHH
PVQVLERMRHAYEAEYSNVHRGLHYLANAMTEAFEGARESARRFLNAASQDEIIFTRSGT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCC
GSINLVANSLGQSIGEGDEIILSIMEHHSNIVPWHFLRERKGAVIKWAPVREDGSFDFEA
CEEEHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHCCCCEEEEEECCCCCCCCHHH
FEQLLTPRTKIVAITHMSNVLGTVTPIKEIVRAAHAVGAKVVVDGCQASVHLPVDVRDLD
HHHHHCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEECCEEEEECC
VDFYAVTGHKLYGPTGIGLLYGKRALLAEMPPYEGGGEMIREVEEGRVTYAEPPHRFEAG
EEEEEEECCEEECCCCCHHHHCCHHHHHCCCCCCCCHHHHHHHHHCCEEECCCCCCCCCC
TPAIVQAIGLGAALDYMDLIGREAIAAHEHDLSVYAHQQLGALNSLRIIGTAKDKGAIVA
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHCCCCCEEEEEECCCCCCEEE
FEMKGAHPHDVATVIDRYGVAVRAGTHCAQPLLARYGTTATCRASFALYNTRSDVDRLVA
EEECCCCCHHHHHHHHHCCCEEECCCHHHHHHHHHCCCCCEEEEEEEEECCHHHHHHHHH
ALLKAQDLFS
HHHHHHHHCC
>Mature Secondary Structure
MVSSPAGRLRIRTLPMTKGHPAVLDGAYDVEKVRADFPALALEVHGHPLTYLDNAASAQK
CCCCCCCCEEEEEECCCCCCCCEECCCHHHHHHHCCCCEEEEEECCCCEEECCCCCCHHH
PVQVLERMRHAYEAEYSNVHRGLHYLANAMTEAFEGARESARRFLNAASQDEIIFTRSGT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCC
GSINLVANSLGQSIGEGDEIILSIMEHHSNIVPWHFLRERKGAVIKWAPVREDGSFDFEA
CEEEHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHCCCCEEEEEECCCCCCCCHHH
FEQLLTPRTKIVAITHMSNVLGTVTPIKEIVRAAHAVGAKVVVDGCQASVHLPVDVRDLD
HHHHHCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEECCEEEEECC
VDFYAVTGHKLYGPTGIGLLYGKRALLAEMPPYEGGGEMIREVEEGRVTYAEPPHRFEAG
EEEEEEECCEEECCCCCHHHHCCHHHHHCCCCCCCCHHHHHHHHHCCEEECCCCCCCCCC
TPAIVQAIGLGAALDYMDLIGREAIAAHEHDLSVYAHQQLGALNSLRIIGTAKDKGAIVA
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHCCCCCEEEEEECCCCCCEEE
FEMKGAHPHDVATVIDRYGVAVRAGTHCAQPLLARYGTTATCRASFALYNTRSDVDRLVA
EEECCCCCHHHHHHHHHCCCEEECCCHHHHHHHHHCCCCCEEEEEEEEECCHHHHHHHHH
ALLKAQDLFS
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA