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The map label for this gene is fbcH [H]

Identifier: 158425123

GI number: 158425123

Start: 4016026

End: 4016859

Strand: Reverse

Name: fbcH [H]

Synonym: AZC_3499

Alternate gene names: 158425123

Gene position: 4016859-4016026 (Counterclockwise)

Preceding gene: 158425124

Following gene: 158425120

Centisome position: 74.81

GC content: 65.11

Gene sequence:

>834_bases
ATGAAGAAGACGTTTCTCCTCGGCGCCGTCGCGCTGGCCCTCGCCTTCGCCGCGCCGGCCCGCGCGGCGGAAGGGGGGCA
TGACGACCTGCCGCACCGCGAAAGCTGGTCCTTCGCCGGGCCGTTCGGCATGTACGATCCGGCCCAGCTCCAGCGCGGTT
TCAAGGTGTTCCGCGAGGTCTGCGCCTCGTGCCACTCGGCCAATTACCTCTACTTCCGCAATCTGGCGCAGGAAGGCGGG
CCGCACTTCTCCGAAGCCCAGGCCAAAGCGGTGGCGTCCGAGTACCAGATTACCGATGGTCCGAACGATCAGGGCGAGAT
GTTCCAGCGCCCCGGCCGCCTCTCGGATCACTGGCCGGCGCCGTTCCCCAATGACCAGGCCGCGCGCGTCGCCAATGGCG
GCGCCCTGCCGCCGGATCTCTCGGTGATCGCCAAGGCCAGAGCCTCGCACGTGGGCTTCCCCGGCTTCATCCTCGACGCC
TTCACCCAGTATCAGGAAGGCGGCGTCGACTATATCCACGCGCTGCTCAACGGCTATGTGGAGCCGCCGGAAGGCGTGAC
CGTGCAGCCGGGCCTGCACTACAACAAGTATTTCCCCGGCCACCAGATCGCCATGCCCAAGCCGCTCAGCGACGGGCAGG
TGGAATATACGGACGGCACGCCCACGACCGTGGATCAATATTCCCGCGACGTGTCGGCCTACCTCATGTGGATGGCAGAG
CCGCACCTCGATGCCCGCAAGCGCATCGGCTTCCAGGTGTTCATCTTCCTCATCGTGCTGGGCGGTCTGCTCTATTTTAC
GAAGAAGAAGATCTGGAAGAACATCGCCCACTGA

Upstream 100 bases:

>100_bases
CTCCATCGCCGATGCGGTTCTGGCCAAGGGTGGCGCAACGGTCGTCGCCGGAGCCTCGGCTCCGCAGACCAAGGGCTGAG
CGAGCGGCGGAGACAGAGCC

Downstream 100 bases:

>100_bases
GGCGATCTCCGTTCCCGCTTCAGACAGGCCCCTTCGCGGGGCCTGTTTTCGTTTGAGAGATCAGAACCGGGTGGCGAGGC
TGACGAACCAGTCCGGCAAG

Product: cytochrome b/c1 precursor

Products: Q; ferrocytochrome c

Alternate protein names: NA

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MKKTFLLGAVALALAFAAPARAAEGGHDDLPHRESWSFAGPFGMYDPAQLQRGFKVFREVCASCHSANYLYFRNLAQEGG
PHFSEAQAKAVASEYQITDGPNDQGEMFQRPGRLSDHWPAPFPNDQAARVANGGALPPDLSVIAKARASHVGFPGFILDA
FTQYQEGGVDYIHALLNGYVEPPEGVTVQPGLHYNKYFPGHQIAMPKPLSDGQVEYTDGTPTTVDQYSRDVSAYLMWMAE
PHLDARKRIGFQVFIFLIVLGGLLYFTKKKIWKNIAH

Sequences:

>Translated_277_residues
MKKTFLLGAVALALAFAAPARAAEGGHDDLPHRESWSFAGPFGMYDPAQLQRGFKVFREVCASCHSANYLYFRNLAQEGG
PHFSEAQAKAVASEYQITDGPNDQGEMFQRPGRLSDHWPAPFPNDQAARVANGGALPPDLSVIAKARASHVGFPGFILDA
FTQYQEGGVDYIHALLNGYVEPPEGVTVQPGLHYNKYFPGHQIAMPKPLSDGQVEYTDGTPTTVDQYSRDVSAYLMWMAE
PHLDARKRIGFQVFIFLIVLGGLLYFTKKKIWKNIAH
>Mature_277_residues
MKKTFLLGAVALALAFAAPARAAEGGHDDLPHRESWSFAGPFGMYDPAQLQRGFKVFREVCASCHSANYLYFRNLAQEGG
PHFSEAQAKAVASEYQITDGPNDQGEMFQRPGRLSDHWPAPFPNDQAARVANGGALPPDLSVIAKARASHVGFPGFILDA
FTQYQEGGVDYIHALLNGYVEPPEGVTVQPGLHYNKYFPGHQIAMPKPLSDGQVEYTDGTPTTVDQYSRDVSAYLMWMAE
PHLDARKRIGFQVFIFLIVLGGLLYFTKKKIWKNIAH

Specific function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. c1 functions as an electron donor to cytochrome c [H]

COG id: COG2857

COG function: function code C; Cytochrome c1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cytochrome c domain [H]

Homologues:

Organism=Homo sapiens, GI21359867, Length=237, Percent_Identity=43.4599156118143, Blast_Score=206, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI17506225, Length=267, Percent_Identity=35.9550561797753, Blast_Score=163, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6324639, Length=242, Percent_Identity=46.6942148760331, Blast_Score=215, Evalue=5e-57,
Organism=Drosophila melanogaster, GI24658292, Length=253, Percent_Identity=39.9209486166008, Blast_Score=187, Evalue=8e-48,
Organism=Drosophila melanogaster, GI21358225, Length=246, Percent_Identity=38.2113821138211, Blast_Score=182, Evalue=2e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016175
- InterPro:   IPR005798
- InterPro:   IPR005797
- InterPro:   IPR002326
- InterPro:   IPR021157
- InterPro:   IPR009056
- InterPro:   IPR016174 [H]

Pfam domain/function: PF00032 Cytochrom_B_C; PF00033 Cytochrom_B_N; PF02167 Cytochrom_C1 [H]

EC number: 1.10.2.2

Molecular weight: Translated: 30589; Mature: 30589

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: PS51007 CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTFLLGAVALALAFAAPARAAEGGHDDLPHRESWSFAGPFGMYDPAQLQRGFKVFREV
CCCHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
CASCHSANYLYFRNLAQEGGPHFSEAQAKAVASEYQITDGPNDQGEMFQRPGRLSDHWPA
HHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCCCCC
PFPNDQAARVANGGALPPDLSVIAKARASHVGFPGFILDAFTQYQEGGVDYIHALLNGYV
CCCCCCHHHHCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCC
EPPEGVTVQPGLHYNKYFPGHQIAMPKPLSDGQVEYTDGTPTTVDQYSRDVSAYLMWMAE
CCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCC
PHLDARKRIGFQVFIFLIVLGGLLYFTKKKIWKNIAH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKTFLLGAVALALAFAAPARAAEGGHDDLPHRESWSFAGPFGMYDPAQLQRGFKVFREV
CCCHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
CASCHSANYLYFRNLAQEGGPHFSEAQAKAVASEYQITDGPNDQGEMFQRPGRLSDHWPA
HHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCCCCC
PFPNDQAARVANGGALPPDLSVIAKARASHVGFPGFILDAFTQYQEGGVDYIHALLNGYV
CCCCCCHHHHCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCC
EPPEGVTVQPGLHYNKYFPGHQIAMPKPLSDGQVEYTDGTPTTVDQYSRDVSAYLMWMAE
CCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCC
PHLDARKRIGFQVFIFLIVLGGLLYFTKKKIWKNIAH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: QH2; ferricytochrome c

Specific reaction: QH2 + 2 ferricytochrome c = Q + 2 ferrocytochrome c

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2541921; 12597275 [H]