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The map label for this gene is uxaB [H]

Identifier: 158424908

GI number: 158424908

Start: 3790511

End: 3791662

Strand: Reverse

Name: uxaB [H]

Synonym: AZC_3284

Alternate gene names: 158424908

Gene position: 3791662-3790511 (Counterclockwise)

Preceding gene: 158424910

Following gene: 158424907

Centisome position: 70.61

GC content: 70.49

Gene sequence:

>1152_bases
GTGACCGGCCGCATCATTCAGTTCGGAACCAGCCGCTTCCTGCAGGCACATGTGGACCTCTTCGTGCACGAGGCGCGCGA
GGCCGGCCAGGCCGTCAGCCCCATCGCCGTCGTGCAGGCTTCGGGTTCCGCCGACCGCGCCGGACGCGTCGCTGCCTTCG
GCCGTCCGGAGGGCTATCCCGTCATCATCCGCGGCCTTGAGAACGGCGCCCGGATCGAGCGCCGGATCGACGTGCGCAGC
GTGGATCGCGGCCTCTCCGCCGCCCGCGACTGGGAGGCCGTGTCCGAGCTCTTCGCAACGGAAGCGGACCTGATCGTTTC
CAACACGGCGGACGCTGGCTACGAGGTGGCGGCAGCCGATCGCGATCCCGCGCTGCTGGCCGGCGGCGTGCCCCAGTCCT
TCCCCGGCAAGCTCACCGCGCTCCTGCACCGCCGCTGGCGGCAGGGCGGTCGTCCGCTCACGGTGCTGCCGTGCGAGCTC
ATCAACGGCAACGGCCGCGTGCTGGCGCAGACCGTGCGCGCGCTCGCCACTGATGCGCAGGCGCCCGCCGCCTTCCTTGC
GTGGCTGGAGCGGGACGTGATCTTCGCCGACACGCTGGTGGACCGCATCGTCTCGCAGGCGCTCGATCCCGTGGGCGCGG
TGGCCGAGCCCTACGCGCTCTGGGCCATCGAACGCCGGCCGGGCCTTGTCGCGCCCTTCGATCATCCCTGCGTGGTGATG
GCGGATGATCTCGGTCCCTTCGAGCGGCTGAAGCTGCACATCCTCAATCTCGGCCACACCGTGCTCGCCGACATCTGGCG
CTCGGAAGGGCGTGATCCGGACGAGACCGTGAAGGCCATCCTTGCCGATGGCGCGGTGCGCGATCGCCTTGATGGCCTCT
ATCGCGCCGAAGTGCTGCCGGGCTTTGCCGCCCATGGCATGGGCGAGGAGGCGCAGGCCTATCTCGCCACCACCATGGAC
CGCTTCCTCAATCCGTTCCTCGATCATCGCATCTCGGACATCGCGCAGAACCACGCCACCAAGGTGGAGCGCCGCATCGC
CGCGTTCCTGAGCTGGTGGGGAGAGGCGGGGGGCGTGCCGGCCACCCCGCTGCTGGACGGCGTGATGGCCAGGCGTGCGT
CGCCGCCGAAAACCGCGCGGAGCGGCGCATGA

Upstream 100 bases:

>100_bases
AGAACGAAAATCAGGGAGAGCGCTCGATGAGCCAGGCTTGGGCTTGCCCGGCAGCCGTGTCTCGAATCCGTTTCGCCTTG
TGGGTGAAAGGCGTCTTCGC

Downstream 100 bases:

>100_bases
CCTATCAGTTCGACTTCGCGGTTCTTCTGCCCTTCTGGCGCGAGTTCGCCATGGGCGTGTGGCTCACGCTGCAACTGTCC
CTGATATCGACGGTGCTGGG

Product: altronate oxidoreductase

Products: NA

Alternate protein names: Tagaturonate dehydrogenase; Tagaturonate reductase [H]

Number of amino acids: Translated: 383; Mature: 382

Protein sequence:

>383_residues
MTGRIIQFGTSRFLQAHVDLFVHEAREAGQAVSPIAVVQASGSADRAGRVAAFGRPEGYPVIIRGLENGARIERRIDVRS
VDRGLSAARDWEAVSELFATEADLIVSNTADAGYEVAAADRDPALLAGGVPQSFPGKLTALLHRRWRQGGRPLTVLPCEL
INGNGRVLAQTVRALATDAQAPAAFLAWLERDVIFADTLVDRIVSQALDPVGAVAEPYALWAIERRPGLVAPFDHPCVVM
ADDLGPFERLKLHILNLGHTVLADIWRSEGRDPDETVKAILADGAVRDRLDGLYRAEVLPGFAAHGMGEEAQAYLATTMD
RFLNPFLDHRISDIAQNHATKVERRIAAFLSWWGEAGGVPATPLLDGVMARRASPPKTARSGA

Sequences:

>Translated_383_residues
MTGRIIQFGTSRFLQAHVDLFVHEAREAGQAVSPIAVVQASGSADRAGRVAAFGRPEGYPVIIRGLENGARIERRIDVRS
VDRGLSAARDWEAVSELFATEADLIVSNTADAGYEVAAADRDPALLAGGVPQSFPGKLTALLHRRWRQGGRPLTVLPCEL
INGNGRVLAQTVRALATDAQAPAAFLAWLERDVIFADTLVDRIVSQALDPVGAVAEPYALWAIERRPGLVAPFDHPCVVM
ADDLGPFERLKLHILNLGHTVLADIWRSEGRDPDETVKAILADGAVRDRLDGLYRAEVLPGFAAHGMGEEAQAYLATTMD
RFLNPFLDHRISDIAQNHATKVERRIAAFLSWWGEAGGVPATPLLDGVMARRASPPKTARSGA
>Mature_382_residues
TGRIIQFGTSRFLQAHVDLFVHEAREAGQAVSPIAVVQASGSADRAGRVAAFGRPEGYPVIIRGLENGARIERRIDVRSV
DRGLSAARDWEAVSELFATEADLIVSNTADAGYEVAAADRDPALLAGGVPQSFPGKLTALLHRRWRQGGRPLTVLPCELI
NGNGRVLAQTVRALATDAQAPAAFLAWLERDVIFADTLVDRIVSQALDPVGAVAEPYALWAIERRPGLVAPFDHPCVVMA
DDLGPFERLKLHILNLGHTVLADIWRSEGRDPDETVKAILADGAVRDRLDGLYRAEVLPGFAAHGMGEEAQAYLATTMDR
FLNPFLDHRISDIAQNHATKVERRIAAFLSWWGEAGGVPATPLLDGVMARRASPPKTARSGA

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG0246

COG function: function code G; Mannitol-1-phosphate/altronate dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannitol dehydrogenase family. UxaB subfamily [H]

Homologues:

Organism=Escherichia coli, GI48994885, Length=370, Percent_Identity=30, Blast_Score=121, Evalue=8e-29,
Organism=Escherichia coli, GI1790779, Length=376, Percent_Identity=28.1914893617021, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1788497, Length=386, Percent_Identity=27.720207253886, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787823, Length=238, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1790028, Length=237, Percent_Identity=26.1603375527426, Blast_Score=74, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6324401, Length=376, Percent_Identity=23.1382978723404, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6320765, Length=376, Percent_Identity=23.1382978723404, Blast_Score=78, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR013118
- InterPro:   IPR013131
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01232 Mannitol_dh; PF08125 Mannitol_dh_C [H]

EC number: =1.1.1.58 [H]

Molecular weight: Translated: 41359; Mature: 41228

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00974 MANNITOL_DHGENASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGRIIQFGTSRFLQAHVDLFVHEAREAGQAVSPIAVVQASGSADRAGRVAAFGRPEGYP
CCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCEEECCCCCCCE
VIIRGLENGARIERRIDVRSVDRGLSAARDWEAVSELFATEADLIVSNTADAGYEVAAAD
EEEEECCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEEECC
RDPALLAGGVPQSFPGKLTALLHRRWRQGGRPLTVLPCELINGNGRVLAQTVRALATDAQ
CCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEEHEEECCCCHHHHHHHHHHHHCCC
APAAFLAWLERDVIFADTLVDRIVSQALDPVGAVAEPYALWAIERRPGLVAPFDHPCVVM
CHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHHHHCCCCEEEEEECCCCCCCCCCCCEEEE
ADDLGPFERLKLHILNLGHTVLADIWRSEGRDPDETVKAILADGAVRDRLDGLYRAEVLP
ECCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCC
GFAAHGMGEEAQAYLATTMDRFLNPFLDHRISDIAQNHATKVERRIAAFLSWWGEAGGVP
CHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
ATPLLDGVMARRASPPKTARSGA
CHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TGRIIQFGTSRFLQAHVDLFVHEAREAGQAVSPIAVVQASGSADRAGRVAAFGRPEGYP
CCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCEEECCCCCCCE
VIIRGLENGARIERRIDVRSVDRGLSAARDWEAVSELFATEADLIVSNTADAGYEVAAAD
EEEEECCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEEECC
RDPALLAGGVPQSFPGKLTALLHRRWRQGGRPLTVLPCELINGNGRVLAQTVRALATDAQ
CCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEEHEEECCCCHHHHHHHHHHHHCCC
APAAFLAWLERDVIFADTLVDRIVSQALDPVGAVAEPYALWAIERRPGLVAPFDHPCVVM
CHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHHHHCCCCEEEEEECCCCCCCCCCCCEEEE
ADDLGPFERLKLHILNLGHTVLADIWRSEGRDPDETVKAILADGAVRDRLDGLYRAEVLP
ECCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCC
GFAAHGMGEEAQAYLATTMDRFLNPFLDHRISDIAQNHATKVERRIAAFLSWWGEAGGVP
CHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
ATPLLDGVMARRASPPKTARSGA
CHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]