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The map label for this gene is yjjN [H]

Identifier: 158424903

GI number: 158424903

Start: 3786492

End: 3787502

Strand: Reverse

Name: yjjN [H]

Synonym: AZC_3279

Alternate gene names: 158424903

Gene position: 3787502-3786492 (Counterclockwise)

Preceding gene: 158424904

Following gene: 158424902

Centisome position: 70.53

GC content: 67.16

Gene sequence:

>1011_bases
ATGAAGGCGTTACTCTGCGAAGAACCCGGCCGCCTGTCGGTGATCAGCCGTCCCGAGCCCGTTCCGGGTCCCGGCGAGGT
GCTGGTACGCATCCGGCGCGTGGGCATCTGCGGCACGGATTTCCATATCTTCCAGGGCAAGCATCCCTTCCTCGAATATC
CCCGCGTGATGGGCCACGAGCTCTCCGGCACGGTGGAGCAGGCGCCGGAAGGCAGCCGTCTCACCAGGGGGGAGAACGTC
TATATCGTGCCCTACCTCTCCTGCGGAAAGTGTGTGGCCTGCCGCAAGGGCGTGACCAATGCCTGTCAGAACATCGCCGT
GCTCGGCGTGCACAGGGATGGCGGCATGGCGGAGTTCCTCTGCGTGCCGGAGCAGAATGTCATTCCGGCGGGCTCGGCCT
CGCTCGATGACGCGGCGATGATCGAGTTCCTCGCCATCGGCGCCCATGGCGTGAAGCGCGGCAGCATCACGGCGCAGGAC
AAGGTCCTGGTGGTGGGCGCCGGGCCCATCGGCATGTCCGCCATCATCTTCGCCAAGGCGCGGGGCGCCGAGGTGTCCGT
GATGGACACCCGCGAGGATCGCCTGAACTTCACCAGGGACGCGCTGGGCGCGAACCATCTGCTCATCGCCGATGCGGGCG
CGGAAGACGTGGCGCGCGGCATCACGGGCGGCGATTTCTATGATGTGGTGATCGACGCCACCGGCCATGCGGGCGCCATG
CAGCGCGGCTTCGGCTTCGTCGCCCATGCGGGCCGCTATGTGCTGGTGAGCGTGGTGCGGCAGGACATCACCTTCTCCGA
TCCGGAGTTCCACAAGCGGGAAACCACGCTCTTCGCCAGCCGCAACGCCCAGCCTGACGATTTCGCCGAGGTGGTGCGCC
AGATGGAGGCGGGCAAGGTGCCCACCCGCGCGCTCAACACCCATCGCGGCGCGCTCTCCGACGCGCCCGCTTTGTTCCAG
GAGTGGCTGCGGCCGGAGGCCGGGGTCATCAAGGCGATCCTGGAAGTCTGA

Upstream 100 bases:

>100_bases
ACGGGACCTCGCTGCCGGAAGACATGTTGAAGTGATTTGACGAGGCGGCCCGGTCTCCACCGGGCCGCCGCCCTGTTCCA
TTTCAGGAAAGACCTGGACG

Downstream 100 bases:

>100_bases
GGTTTCTTCATGTCCAGCCCGCGCACGCTGCGTCTCCACGAGACGGACAATGTCGTCATCGTCCTCGATACCGTTGCTCG
GGGCGCGGCGCTGGCTGGCG

Product: zinc-binding dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MKALLCEEPGRLSVISRPEPVPGPGEVLVRIRRVGICGTDFHIFQGKHPFLEYPRVMGHELSGTVEQAPEGSRLTRGENV
YIVPYLSCGKCVACRKGVTNACQNIAVLGVHRDGGMAEFLCVPEQNVIPAGSASLDDAAMIEFLAIGAHGVKRGSITAQD
KVLVVGAGPIGMSAIIFAKARGAEVSVMDTREDRLNFTRDALGANHLLIADAGAEDVARGITGGDFYDVVIDATGHAGAM
QRGFGFVAHAGRYVLVSVVRQDITFSDPEFHKRETTLFASRNAQPDDFAEVVRQMEAGKVPTRALNTHRGALSDAPALFQ
EWLRPEAGVIKAILEV

Sequences:

>Translated_336_residues
MKALLCEEPGRLSVISRPEPVPGPGEVLVRIRRVGICGTDFHIFQGKHPFLEYPRVMGHELSGTVEQAPEGSRLTRGENV
YIVPYLSCGKCVACRKGVTNACQNIAVLGVHRDGGMAEFLCVPEQNVIPAGSASLDDAAMIEFLAIGAHGVKRGSITAQD
KVLVVGAGPIGMSAIIFAKARGAEVSVMDTREDRLNFTRDALGANHLLIADAGAEDVARGITGGDFYDVVIDATGHAGAM
QRGFGFVAHAGRYVLVSVVRQDITFSDPEFHKRETTLFASRNAQPDDFAEVVRQMEAGKVPTRALNTHRGALSDAPALFQ
EWLRPEAGVIKAILEV
>Mature_336_residues
MKALLCEEPGRLSVISRPEPVPGPGEVLVRIRRVGICGTDFHIFQGKHPFLEYPRVMGHELSGTVEQAPEGSRLTRGENV
YIVPYLSCGKCVACRKGVTNACQNIAVLGVHRDGGMAEFLCVPEQNVIPAGSASLDDAAMIEFLAIGAHGVKRGSITAQD
KVLVVGAGPIGMSAIIFAKARGAEVSVMDTREDRLNFTRDALGANHLLIADAGAEDVARGITGGDFYDVVIDATGHAGAM
QRGFGFVAHAGRYVLVSVVRQDITFSDPEFHKRETTLFASRNAQPDDFAEVVRQMEAGKVPTRALNTHRGALSDAPALFQ
EWLRPEAGVIKAILEV

Specific function: Putative L-galactonate oxidoreductase that is required for growth on L-galactonate as the sole carbon source [H]

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI156627571, Length=341, Percent_Identity=31.9648093841642, Blast_Score=123, Evalue=3e-28,
Organism=Escherichia coli, GI226510992, Length=313, Percent_Identity=44.408945686901, Blast_Score=258, Evalue=5e-70,
Organism=Escherichia coli, GI1787863, Length=338, Percent_Identity=34.3195266272189, Blast_Score=173, Evalue=1e-44,
Organism=Escherichia coli, GI1788073, Length=353, Percent_Identity=28.328611898017, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI87082125, Length=343, Percent_Identity=30.0291545189504, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1790045, Length=274, Percent_Identity=31.3868613138686, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1788407, Length=300, Percent_Identity=27.3333333333333, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1786825, Length=266, Percent_Identity=31.203007518797, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1788075, Length=332, Percent_Identity=24.3975903614458, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1790718, Length=225, Percent_Identity=28.8888888888889, Blast_Score=84, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17562876, Length=333, Percent_Identity=29.4294294294294, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17562878, Length=197, Percent_Identity=34.010152284264, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17562582, Length=332, Percent_Identity=27.1084337349398, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6319955, Length=349, Percent_Identity=27.7936962750716, Blast_Score=110, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6322619, Length=349, Percent_Identity=27.7936962750716, Blast_Score=109, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6323099, Length=351, Percent_Identity=26.7806267806268, Blast_Score=99, Evalue=9e-22,
Organism=Saccharomyces cerevisiae, GI6319258, Length=358, Percent_Identity=25.9776536312849, Blast_Score=94, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6319257, Length=319, Percent_Identity=28.2131661442006, Blast_Score=94, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6323729, Length=200, Percent_Identity=27.5, Blast_Score=69, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6324486, Length=205, Percent_Identity=27.3170731707317, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323961, Length=193, Percent_Identity=28.4974093264249, Blast_Score=64, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6320033, Length=213, Percent_Identity=27.2300469483568, Blast_Score=63, Evalue=7e-11,
Organism=Drosophila melanogaster, GI17137530, Length=342, Percent_Identity=28.9473684210526, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI17737897, Length=346, Percent_Identity=27.4566473988439, Blast_Score=100, Evalue=9e-22,
Organism=Drosophila melanogaster, GI45550770, Length=179, Percent_Identity=29.608938547486, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI45551930, Length=179, Percent_Identity=29.608938547486, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI221457811, Length=179, Percent_Identity=29.608938547486, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 36012; Mature: 36012

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALLCEEPGRLSVISRPEPVPGPGEVLVRIRRVGICGTDFHIFQGKHPFLEYPRVMGHE
CCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCHHHCHHHHCCC
LSGTVEQAPEGSRLTRGENVYIVPYLSCGKCVACRKGVTNACQNIAVLGVHRDGGMAEFL
CCCCHHCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCEEEEEEECCCCCEEEE
CVPEQNVIPAGSASLDDAAMIEFLAIGAHGVKRGSITAQDKVLVVGAGPIGMSAIIFAKA
ECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEEEC
RGAEVSVMDTREDRLNFTRDALGANHLLIADAGAEDVARGITGGDFYDVVIDATGHAGAM
CCCEEEEEECCHHHHHHHHHHCCCCEEEEEECCHHHHHHCCCCCCEEEEEEECCCCCCHH
QRGFGFVAHAGRYVLVSVVRQDITFSDPEFHKRETTLFASRNAQPDDFAEVVRQMEAGKV
HHCCHHHHHCCHHHHHHHHHHCCCCCCCCHHCHHEEEEECCCCCCHHHHHHHHHHHCCCC
PTRALNTHRGALSDAPALFQEWLRPEAGVIKAILEV
CHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHCC
>Mature Secondary Structure
MKALLCEEPGRLSVISRPEPVPGPGEVLVRIRRVGICGTDFHIFQGKHPFLEYPRVMGHE
CCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCHHHCHHHHCCC
LSGTVEQAPEGSRLTRGENVYIVPYLSCGKCVACRKGVTNACQNIAVLGVHRDGGMAEFL
CCCCHHCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCEEEEEEECCCCCEEEE
CVPEQNVIPAGSASLDDAAMIEFLAIGAHGVKRGSITAQDKVLVVGAGPIGMSAIIFAKA
ECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEEEC
RGAEVSVMDTREDRLNFTRDALGANHLLIADAGAEDVARGITGGDFYDVVIDATGHAGAM
CCCEEEEEECCHHHHHHHHHHCCCCEEEEEECCHHHHHHCCCCCCEEEEEEECCCCCCHH
QRGFGFVAHAGRYVLVSVVRQDITFSDPEFHKRETTLFASRNAQPDDFAEVVRQMEAGKV
HHCCHHHHHCCHHHHHHHHHHCCCCCCCCHHCHHEEEEECCCCCCHHHHHHHHHHHCCCC
PTRALNTHRGALSDAPALFQEWLRPEAGVIKAILEV
CHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]