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The map label for this gene is iucD [H]

Identifier: 158424871

GI number: 158424871

Start: 3747613

End: 3748779

Strand: Direct

Name: iucD [H]

Synonym: AZC_3247

Alternate gene names: 158424871

Gene position: 3747613-3748779 (Clockwise)

Preceding gene: 158424870

Following gene: 158424872

Centisome position: 69.79

GC content: 65.98

Gene sequence:

>1167_bases
GTGCGAACCCGAGGGCCTGCGGCATCATGGAGCCTGGAAGCGATGACAGACCCTATTCTCGACCTCGCCGGAATCGGCAT
CGGCCCGTTCAACCTCAGCCTTGCCGCGCAGCTTGACGGCCTGCCGGACATGAACGCGCGCTTCTTCGAGCAGCGGCCAG
CCTTCTCCTGGCATCCCGGCATGATGCTGCCCGGTGCCGAACTCCAGACGTCCTGTCTGAAGGATCTCGTCACCGCCACC
AATCCGACCAGCCCCTGGTCCTTCATGGCCTATCTGGTGGCGCACAAGCGCTTCTATGACTTCATGAACGCCGAGTTCGA
CGCCCTGCCACGGCAGGAATTCGCCAACTATCTCGCCTGGGCCGCCAACGGCATCGAGAGCCTGCGCTTCGGCAAGCCTG
TGCGGGCCCTGGACTTCAGCCAGGGCCAGTTCGTGCTCGGTTTCGACGATGGCGAGGTAGCGGCGCGCAACGTCTGCCTG
GGCATCGGCCTCGTGCCGGACCTGCCGGCTTTCGCCATGCCGCTCGCCGGCGACACCTGCTTCCACGCCTCTGCCGCGAC
GGCGCGCCTCCCTCTGCTCAACGCGGGCCGCGTCGCCGTGGTGGGCGGCGGCCAGAGTGGTGCGGAGGTGTTTCTTTCGT
TGCTTTCGCAGGTCGGAACCGCGAGCGAGGTGTCGTGGATCAGCCGGCGGCCCAATTTCGAGCCGCTGGACGCCACGCCC
TTCACCAACGAGCTGTTCACGCCGGGCTATGTGACGGACTTCCATGGCATCGGGGAGGACGCGCGCAATGCCAGCCTGGC
CCGGCAGAAGCTCGCGAGCGACGGAGCATCGGCCTCGACCCTGAAGGCCATCTACCAGCGGCTCTATGCCCTGCGTCATC
TGGGCGAGGGTGCTCTCAACCCCACGCTGATGCCCGGTCGCGAAGTCATCCAGATGGAGCGCCAGCGCGGCGAATATCGC
CTGGTCATGCGCAACGGTTTCGATGGCGGCATCGAAATCGTGCATGCGGACGCAGTGGTGCTCGCGACCGGCTACGGCTT
CCGCGTGCCGGAATTCCTCGCGCCGCTGCGTGACCGGATCGCCTTCGACCGCAAGGGGTTGTTCCAGGTCAATCCGGACT
TCTCCCTCACCTGGGATGGACCGCGCCAGAATCGCATCTTCGCCTGA

Upstream 100 bases:

>100_bases
GCCATGACAGGCTTCGAACAGGCGGCCGAATGAACGGCCGATCACCGTCGCAGACGCCGCGCATCCCGAGGCGCGGACTT
GAGGAAGCCCGCCGCAGCTC

Downstream 100 bases:

>100_bases
ACGCCAGTCGCCACAGCCACGGCATCGCCGAACCCCAGCTCAGCCTCATGGCGTGGCGCAGTTCCGTGGTGGCGAACGCG
CTGACCGGGCGGTCGCATTT

Product: L-lysine 6-monooxygenase

Products: NA

Alternate protein names: Lysine 6-N-hydroxylase; Lysine N(6)-hydroxylase; Lysine-N-oxygenase [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MRTRGPAASWSLEAMTDPILDLAGIGIGPFNLSLAAQLDGLPDMNARFFEQRPAFSWHPGMMLPGAELQTSCLKDLVTAT
NPTSPWSFMAYLVAHKRFYDFMNAEFDALPRQEFANYLAWAANGIESLRFGKPVRALDFSQGQFVLGFDDGEVAARNVCL
GIGLVPDLPAFAMPLAGDTCFHASAATARLPLLNAGRVAVVGGGQSGAEVFLSLLSQVGTASEVSWISRRPNFEPLDATP
FTNELFTPGYVTDFHGIGEDARNASLARQKLASDGASASTLKAIYQRLYALRHLGEGALNPTLMPGREVIQMERQRGEYR
LVMRNGFDGGIEIVHADAVVLATGYGFRVPEFLAPLRDRIAFDRKGLFQVNPDFSLTWDGPRQNRIFA

Sequences:

>Translated_388_residues
MRTRGPAASWSLEAMTDPILDLAGIGIGPFNLSLAAQLDGLPDMNARFFEQRPAFSWHPGMMLPGAELQTSCLKDLVTAT
NPTSPWSFMAYLVAHKRFYDFMNAEFDALPRQEFANYLAWAANGIESLRFGKPVRALDFSQGQFVLGFDDGEVAARNVCL
GIGLVPDLPAFAMPLAGDTCFHASAATARLPLLNAGRVAVVGGGQSGAEVFLSLLSQVGTASEVSWISRRPNFEPLDATP
FTNELFTPGYVTDFHGIGEDARNASLARQKLASDGASASTLKAIYQRLYALRHLGEGALNPTLMPGREVIQMERQRGEYR
LVMRNGFDGGIEIVHADAVVLATGYGFRVPEFLAPLRDRIAFDRKGLFQVNPDFSLTWDGPRQNRIFA
>Mature_388_residues
MRTRGPAASWSLEAMTDPILDLAGIGIGPFNLSLAAQLDGLPDMNARFFEQRPAFSWHPGMMLPGAELQTSCLKDLVTAT
NPTSPWSFMAYLVAHKRFYDFMNAEFDALPRQEFANYLAWAANGIESLRFGKPVRALDFSQGQFVLGFDDGEVAARNVCL
GIGLVPDLPAFAMPLAGDTCFHASAATARLPLLNAGRVAVVGGGQSGAEVFLSLLSQVGTASEVSWISRRPNFEPLDATP
FTNELFTPGYVTDFHGIGEDARNASLARQKLASDGASASTLKAIYQRLYALRHLGEGALNPTLMPGREVIQMERQRGEYR
LVMRNGFDGGIEIVHADAVVLATGYGFRVPEFLAPLRDRIAFDRKGLFQVNPDFSLTWDGPRQNRIFA

Specific function: This is one of the proteins involved in the biosynthesis of siderophores (such as the dihydroxamate siderophore, aerobactin), which are chelators that mediate the high-affinity iron transport systems induced by the organism under iron-stressed conditions

COG id: COG3486

COG function: function code Q; Lysine/ornithine N-monooxygenase

Gene ontology:

Cell location: Cytoplasm. Cell membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027 [H]

Pfam domain/function: PF07992 Pyr_redox_2 [H]

EC number: =1.14.13.59 [H]

Molecular weight: Translated: 42354; Mature: 42354

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTRGPAASWSLEAMTDPILDLAGIGIGPFNLSLAAQLDGLPDMNARFFEQRPAFSWHPG
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHHHHCCCCCCCCCC
MMLPGAELQTSCLKDLVTATNPTSPWSFMAYLVAHKRFYDFMNAEFDALPRQEFANYLAW
CCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHH
AANGIESLRFGKPVRALDFSQGQFVLGFDDGEVAARNVCLGIGLVPDLPAFAMPLAGDTC
HHCCHHHHHCCCCCCEEECCCCCEEEEECCCCHHHHHEEEECCCCCCCCHHHCCCCCCCC
FHASAATARLPLLNAGRVAVVGGGQSGAEVFLSLLSQVGTASEVSWISRRPNFEPLDATP
CCCCCHHHCCCEECCCCEEEEECCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCC
FTNELFTPGYVTDFHGIGEDARNASLARQKLASDGASASTLKAIYQRLYALRHLGEGALN
CCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCC
PTLMPGREVIQMERQRGEYRLVMRNGFDGGIEIVHADAVVLATGYGFRVPEFLAPLRDRI
CCCCCCHHHHHHHHHCCCEEEEEECCCCCCEEEEEECEEEEECCCCCCCHHHHHHHHHHH
AFDRKGLFQVNPDFSLTWDGPRQNRIFA
HHCCCCCEEECCCEEEEECCCCCCCCCC
>Mature Secondary Structure
MRTRGPAASWSLEAMTDPILDLAGIGIGPFNLSLAAQLDGLPDMNARFFEQRPAFSWHPG
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHHHHCCCCCCCCCC
MMLPGAELQTSCLKDLVTATNPTSPWSFMAYLVAHKRFYDFMNAEFDALPRQEFANYLAW
CCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHH
AANGIESLRFGKPVRALDFSQGQFVLGFDDGEVAARNVCLGIGLVPDLPAFAMPLAGDTC
HHCCHHHHHCCCCCCEEECCCCCEEEEECCCCHHHHHEEEECCCCCCCCHHHCCCCCCCC
FHASAATARLPLLNAGRVAVVGGGQSGAEVFLSLLSQVGTASEVSWISRRPNFEPLDATP
CCCCCHHHCCCEECCCCEEEEECCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCC
FTNELFTPGYVTDFHGIGEDARNASLARQKLASDGASASTLKAIYQRLYALRHLGEGALN
CCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCC
PTLMPGREVIQMERQRGEYRLVMRNGFDGGIEIVHADAVVLATGYGFRVPEFLAPLRDRI
CCCCCCHHHHHHHHHCCCEEEEEECCCCCCEEEEEECEEEEECCCCCCCHHHHHHHHHHH
AFDRKGLFQVNPDFSLTWDGPRQNRIFA
HHCCCCCEEECCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3275632; 10064136 [H]