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The map label for this gene is lgrC [H]

Identifier: 158424870

GI number: 158424870

Start: 3743511

End: 3747545

Strand: Direct

Name: lgrC [H]

Synonym: AZC_3246

Alternate gene names: 158424870

Gene position: 3743511-3747545 (Clockwise)

Preceding gene: 158424866

Following gene: 158424871

Centisome position: 69.71

GC content: 69.14

Gene sequence:

>4035_bases
ATGGGCGGATCTGCGCCCCAGCTCCAACCGGGAGGCCGCGCGATGACGCACGCCGATGCCGCCGTGGAGACAAAGGATCA
CGAACTCAAAGGCTATGATCTGACCCCGTCCCAGCGTCGCGTCTGGTCGCTGGAGCAGATCGGCAACAGCGCCGTCGCGG
GGCGTCCGCTGCTGGAGCTCGGCCTCTCCGGGCCGCTGGATGTCACGACGCTGCGAACCGCGCTTGACCGGCTTGCACTC
CGCCATCCCGCCCTGCGTCTGCGGTTCCGCGTTCATCCCGGTGGGCGCGTACTCCAGTTGCCCGACGATGCGGCGGCGCT
GCCGCTGTCCGTCTGCGACCTCTCCGCCCAGACCAGCGGCGACGCGGCGCACGCGTATCAGCGGATACGCAACGAGCTTG
CCGTTCCAGACATCGAGACCGGAGTGCCCGCGCAGGCGGTGCTCGTTCGCCTTTCGGCGCACGAGGCCCGTCTGCTGATC
GTGCTGCACCCGATCATCTGCGATACCGTCTCGCTCGACATTCTCGCCGACAGTTTCGCCCTGCTCTATGCGGATGCGGA
GGCAGGTTCAGCGGGCTTGTCGCTGGCCGGGGCGCCGCTGGCCTGGCTGGAGAGGCCCGAGGCCAGCCCCGAGACTCTGT
CGCAGTGGGAAACCCGCCTTGCGGACGACCACGCCGACGCGACGCTCCCCCTCGCCGGGCGACGCGAGACCCGGGTGGAT
GGCGCGCGCAGCGCACAGCTCCAGACGCTGGGCACGGCCGAGGCGGAAGCCGCCCGCGCGGCAGCCACGGCCTGCGGCAC
ATCGCTCGCGCTGTTTCTGTCTGCCGCATTCGGCGTCCTGTTGACCCGCTACAGCGGACAGACCCGGCTGAAGTACGGCG
TCGCGCTGGACGCCCCCCTCGGCGGCGAACGGCGGGAGATCGGGCGCGTGGCGGACGTGCTGCCGCTGCTGCTCGACCTC
TCCTCCGGCCTCTCGTTCAAGGACGCCCTCGGTCGCGTGGCGGAGGCGCTGGACGCGGCACGCAGCCATTACGTGCCGTT
CGAGACGCTGGCCCAGACCTTCTGGGTCAACAACGAGGACAACGGGCGCGGCTTCCTGCCCAGCGTGCACATGCACCGGC
CCTTGCCGCCGGCCGTCGTCATCACGCCCGGCGGACTGCGGATCACCGCCATCGCCCAGCCTCCTCTGCCATTGGATGCC
GATTTCCTCTTCATCTCCCGCGATCTTCCGGACGGCAGCATCGAACTCGTGCTGGACCATCCGGCGGGACTGTTCGACCC
GCGTCTCGTCGACCGCGCCCTGACCCATCTGGCGCGGATCATCGGTGCGGCATCTGCCGGCCCTGAAAAGAGCCTCAGGG
ACATCCAACTCGTCTCGCCGGCCGAGCTTGAGGCCCTGTCCCGGCCCTATCCCGATGGTGCCCGGGATGATCCCCGGCCG
GTCCATGCGCTGATCGCCGGGCACGTCCCGCGGGCGCCGGAAACACCCGCCATCTTTTTCGGCGACACGGTGTGGACCCG
CGCGGCACTTGATCGCTACGCCAACCGGATCGCCAATATGCTGCTCGCTGCCGGAGCCCGGCGCGAGAGCTGCGTGGCGG
TCGCCCTGCGGCGGTCGCCGGAAGCCATCGGCGCCATCCTCGGCGTTCTCAAGGCGGGCGCAGCCTTCATCCCCGTCGAA
CCGGACCACCCCGCCCAGCGCAACGACCATATTCTCGCCGATGCCGGTGTGGCCGTGATCCTGACCACGCGGGCGCTGCG
CGCCAAGCTGCGGCCCGCGCAGGGCACTACGGTCATAGAACTCGACGCCGTGAACCTTGCCGAGGTGCCCGACAGCGACC
CTCTGGTGACCATCACCGACCGGCAGCTGGCCTATGTGATCTACACCTCCGGCTCCACGGGCAAGCCCAAGGGCGTGGCG
GTGGAACACGGACCGCTGACCCGGCACCTGCAGGCGACCGCGCGGGTCTATGAGATGGACGAGACGTCACGGGAGCTGCC
GTTCCTGCCCTTCTCGTCCGACGGCGGGCACGAACGCTGGATGGTACCGCTCATGCTCGGCGGCAGCATCGTCCTGCCCG
ACAAACCGCTCTGGACGCCCGAGGAAACCTTCGCCGCCATGCGCCGCCATGGCGTCAACAATGCGAGCTTTCCAACCACC
TACGTCCAGCAGTTGGCCGAATGGGCCGAGGCGACGGGGGAAGCCCCGCCTGTGCGGCTCTATTCCTTCGGCGGCGAAGG
CATGGCGCAGGCCACCTTCGATCTCTTCTCCCGCGCCCTGAAGGCACAGACGCTGATCAACGGCTATGGTCCGACAGAGA
CCATCATGACGCCGATGGTGTGGAAGGTCCGGTCCGGCACCTCCTTCGAGGGCACGTACGCCCCCATCGGACGGGCGGTC
GGGCTCCGGCGCATCTACGTGCTCGATCCCGATCTCAACCCGGTGCCGATCGGGGTCACGGGGGAACTCTATATCGGCGG
CGACGGCGTTGCCCGCGGCTATGTTAACCGGCCCGGCGCCACCGCCGAGCGCTTCATTCCCGATCCCTTCGGCGGAGACG
GCGGGCGGCTTTACGCCTCAGGCGATCTGGCCCGCTGGCGCGAGGACGGAACGGTGGAGTTCGTCGGCCGCGTGGACCAT
CAGGTCAAGCTGCGCGGATACCGCATCGAACCCGGCGAGATCGAGGCCGCCCTGCGCACCCTGCCGGGTGTCAGTGAATG
CGCGGTCGTGTTGCGCCACGACGCCGGCCAGCCGGCGCTCGTGGCCTATGCGGTCCCGGCCCGCGGTGCCCGCCTCGATG
GAGCGGAGGTGCGCCGCGCCCTCGCCGGGCTCCTGCCCGAGCATATGGTGCCCTCCGCCGTCGTGGTGCTGGAGAAGATG
CCGCTCAACGCCAACAGCAAGCTCGATCGCGCCGCCCTGCCGGCGCCGGGCTTCGCGCTGCTGGAAGTGGTTCCGCCCTC
CACGCCGCTGGAGGCGGACATCTGCGCCATGTGGCGCGACACGCTGGGGCTGCCTGAGGTCGGGGTCACGCAGAACTTCT
TCGAGATGGGCGGCAACTCGATGGCCGCACTGCGAATCCTCGGCCGCATCCGGAAGCTCAAGCCGGAGGCGGACGTCGCC
ATCGCGGACCTCTTCAATCACCAGACCATCCGCGACCTGGCAACCGCCATCGAGCGCGGCCCGCGCCCGGGTGGCGGGCA
GCTCATTCACCTGCGCAGCACCGGCCGGCGGCCGATACTCTACTGCTTCCCCGGACTGCTGGTGAGCACCCGCGAATATG
TGAAGCTGGTGGACCACCTCGGGCCGGACCAGCCCGCCACCGGCTTCATCTGTTACTCGCTGGCCGAGGACAAGGGCCGC
GAAGCTTCCGTCACGGAGATCACCGCCCGCTATGCGGAACTGGTGCGGGCCCACTCGAAGGGCGAACCCTGCTTTTTCCT
TGGCTGGTCCTGGGGCGGTCTGCTCGCCTACGAGGCGGCGCGGATGCTCGGCAGCGACATCGACCTGAAGCTGATCGGCA
TGATCGACGTCTGCGACATGGACACGGAATTTGCCATCGGCGCCATTCCCCGCTTCGCGCCCGGCGAGCGCGAGGCGCTC
GCGGCACGCGTCGAGGCCTGGCTCGCGCGCACGCCGATGGCTGCGCGCTGGCATGACCTGATCGGCGCCATGGATGCGCT
CGCCTACGACCAGTTCCTGCGTTTCGTCGGCAACAGTCCGGAAGGGCTGCCGGAGGATGGGCCGGACATCGGCAGCCGCG
AGCACACGTTCTGGGTGCTGATCGACAACGCGCTGATCTTCCGCCGCCACAAGATGCTGCCCCACGACTGTCCCATCCAG
CCCTGGGCGGCGGCGGATTCGCTCAATCGCGGCCTCAACCTCATCGACTGGCGCCAGCTCTCACGCCGCGCCGCCCCCGC
CGAGATCATCGAGGGCACGACCCACCTCCACATCATCGGCGCGCCGGCCTTCCATGCCCGGTTCGCCCGCAAGCTCGACG
AAGCCATGACAGGCTTCGAACAGGCGGCCGAATGA

Upstream 100 bases:

>100_bases
GCCATGCCCTCTGGCCCGTCTGGCGGCCCGTTCCCAACGGATGGCAGGCCGTCGCCGTCACCGGAAGCGCTGCGCATTGC
CTCGCCTACGTGGACGCCAC

Downstream 100 bases:

>100_bases
ACGGCCGATCACCGTCGCAGACGCCGCGCATCCCGAGGCGCGGACTTGAGGAAGCCCGCCGCAGCTCGTGCGAACCCGAG
GGCCTGCGGCATCATGGAGC

Product: vicibactin biosynthesis non-ribosomal peptide synthase

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: ATP-dependent valine adenylase; ValA; Valine activase; ATP-dependent D-valine adenylase; D-ValA; D-valine activase; Valine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan/phenylalanine/tyrosine adenylase; Trp/Phe/TyrA; Tryptophan/phenylalanine/tyrosine activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing] [H]

Number of amino acids: Translated: 1344; Mature: 1343

Protein sequence:

>1344_residues
MGGSAPQLQPGGRAMTHADAAVETKDHELKGYDLTPSQRRVWSLEQIGNSAVAGRPLLELGLSGPLDVTTLRTALDRLAL
RHPALRLRFRVHPGGRVLQLPDDAAALPLSVCDLSAQTSGDAAHAYQRIRNELAVPDIETGVPAQAVLVRLSAHEARLLI
VLHPIICDTVSLDILADSFALLYADAEAGSAGLSLAGAPLAWLERPEASPETLSQWETRLADDHADATLPLAGRRETRVD
GARSAQLQTLGTAEAEAARAAATACGTSLALFLSAAFGVLLTRYSGQTRLKYGVALDAPLGGERREIGRVADVLPLLLDL
SSGLSFKDALGRVAEALDAARSHYVPFETLAQTFWVNNEDNGRGFLPSVHMHRPLPPAVVITPGGLRITAIAQPPLPLDA
DFLFISRDLPDGSIELVLDHPAGLFDPRLVDRALTHLARIIGAASAGPEKSLRDIQLVSPAELEALSRPYPDGARDDPRP
VHALIAGHVPRAPETPAIFFGDTVWTRAALDRYANRIANMLLAAGARRESCVAVALRRSPEAIGAILGVLKAGAAFIPVE
PDHPAQRNDHILADAGVAVILTTRALRAKLRPAQGTTVIELDAVNLAEVPDSDPLVTITDRQLAYVIYTSGSTGKPKGVA
VEHGPLTRHLQATARVYEMDETSRELPFLPFSSDGGHERWMVPLMLGGSIVLPDKPLWTPEETFAAMRRHGVNNASFPTT
YVQQLAEWAEATGEAPPVRLYSFGGEGMAQATFDLFSRALKAQTLINGYGPTETIMTPMVWKVRSGTSFEGTYAPIGRAV
GLRRIYVLDPDLNPVPIGVTGELYIGGDGVARGYVNRPGATAERFIPDPFGGDGGRLYASGDLARWREDGTVEFVGRVDH
QVKLRGYRIEPGEIEAALRTLPGVSECAVVLRHDAGQPALVAYAVPARGARLDGAEVRRALAGLLPEHMVPSAVVVLEKM
PLNANSKLDRAALPAPGFALLEVVPPSTPLEADICAMWRDTLGLPEVGVTQNFFEMGGNSMAALRILGRIRKLKPEADVA
IADLFNHQTIRDLATAIERGPRPGGGQLIHLRSTGRRPILYCFPGLLVSTREYVKLVDHLGPDQPATGFICYSLAEDKGR
EASVTEITARYAELVRAHSKGEPCFFLGWSWGGLLAYEAARMLGSDIDLKLIGMIDVCDMDTEFAIGAIPRFAPGEREAL
AARVEAWLARTPMAARWHDLIGAMDALAYDQFLRFVGNSPEGLPEDGPDIGSREHTFWVLIDNALIFRRHKMLPHDCPIQ
PWAAADSLNRGLNLIDWRQLSRRAAPAEIIEGTTHLHIIGAPAFHARFARKLDEAMTGFEQAAE

Sequences:

>Translated_1344_residues
MGGSAPQLQPGGRAMTHADAAVETKDHELKGYDLTPSQRRVWSLEQIGNSAVAGRPLLELGLSGPLDVTTLRTALDRLAL
RHPALRLRFRVHPGGRVLQLPDDAAALPLSVCDLSAQTSGDAAHAYQRIRNELAVPDIETGVPAQAVLVRLSAHEARLLI
VLHPIICDTVSLDILADSFALLYADAEAGSAGLSLAGAPLAWLERPEASPETLSQWETRLADDHADATLPLAGRRETRVD
GARSAQLQTLGTAEAEAARAAATACGTSLALFLSAAFGVLLTRYSGQTRLKYGVALDAPLGGERREIGRVADVLPLLLDL
SSGLSFKDALGRVAEALDAARSHYVPFETLAQTFWVNNEDNGRGFLPSVHMHRPLPPAVVITPGGLRITAIAQPPLPLDA
DFLFISRDLPDGSIELVLDHPAGLFDPRLVDRALTHLARIIGAASAGPEKSLRDIQLVSPAELEALSRPYPDGARDDPRP
VHALIAGHVPRAPETPAIFFGDTVWTRAALDRYANRIANMLLAAGARRESCVAVALRRSPEAIGAILGVLKAGAAFIPVE
PDHPAQRNDHILADAGVAVILTTRALRAKLRPAQGTTVIELDAVNLAEVPDSDPLVTITDRQLAYVIYTSGSTGKPKGVA
VEHGPLTRHLQATARVYEMDETSRELPFLPFSSDGGHERWMVPLMLGGSIVLPDKPLWTPEETFAAMRRHGVNNASFPTT
YVQQLAEWAEATGEAPPVRLYSFGGEGMAQATFDLFSRALKAQTLINGYGPTETIMTPMVWKVRSGTSFEGTYAPIGRAV
GLRRIYVLDPDLNPVPIGVTGELYIGGDGVARGYVNRPGATAERFIPDPFGGDGGRLYASGDLARWREDGTVEFVGRVDH
QVKLRGYRIEPGEIEAALRTLPGVSECAVVLRHDAGQPALVAYAVPARGARLDGAEVRRALAGLLPEHMVPSAVVVLEKM
PLNANSKLDRAALPAPGFALLEVVPPSTPLEADICAMWRDTLGLPEVGVTQNFFEMGGNSMAALRILGRIRKLKPEADVA
IADLFNHQTIRDLATAIERGPRPGGGQLIHLRSTGRRPILYCFPGLLVSTREYVKLVDHLGPDQPATGFICYSLAEDKGR
EASVTEITARYAELVRAHSKGEPCFFLGWSWGGLLAYEAARMLGSDIDLKLIGMIDVCDMDTEFAIGAIPRFAPGEREAL
AARVEAWLARTPMAARWHDLIGAMDALAYDQFLRFVGNSPEGLPEDGPDIGSREHTFWVLIDNALIFRRHKMLPHDCPIQ
PWAAADSLNRGLNLIDWRQLSRRAAPAEIIEGTTHLHIIGAPAFHARFARKLDEAMTGFEQAAE
>Mature_1343_residues
GGSAPQLQPGGRAMTHADAAVETKDHELKGYDLTPSQRRVWSLEQIGNSAVAGRPLLELGLSGPLDVTTLRTALDRLALR
HPALRLRFRVHPGGRVLQLPDDAAALPLSVCDLSAQTSGDAAHAYQRIRNELAVPDIETGVPAQAVLVRLSAHEARLLIV
LHPIICDTVSLDILADSFALLYADAEAGSAGLSLAGAPLAWLERPEASPETLSQWETRLADDHADATLPLAGRRETRVDG
ARSAQLQTLGTAEAEAARAAATACGTSLALFLSAAFGVLLTRYSGQTRLKYGVALDAPLGGERREIGRVADVLPLLLDLS
SGLSFKDALGRVAEALDAARSHYVPFETLAQTFWVNNEDNGRGFLPSVHMHRPLPPAVVITPGGLRITAIAQPPLPLDAD
FLFISRDLPDGSIELVLDHPAGLFDPRLVDRALTHLARIIGAASAGPEKSLRDIQLVSPAELEALSRPYPDGARDDPRPV
HALIAGHVPRAPETPAIFFGDTVWTRAALDRYANRIANMLLAAGARRESCVAVALRRSPEAIGAILGVLKAGAAFIPVEP
DHPAQRNDHILADAGVAVILTTRALRAKLRPAQGTTVIELDAVNLAEVPDSDPLVTITDRQLAYVIYTSGSTGKPKGVAV
EHGPLTRHLQATARVYEMDETSRELPFLPFSSDGGHERWMVPLMLGGSIVLPDKPLWTPEETFAAMRRHGVNNASFPTTY
VQQLAEWAEATGEAPPVRLYSFGGEGMAQATFDLFSRALKAQTLINGYGPTETIMTPMVWKVRSGTSFEGTYAPIGRAVG
LRRIYVLDPDLNPVPIGVTGELYIGGDGVARGYVNRPGATAERFIPDPFGGDGGRLYASGDLARWREDGTVEFVGRVDHQ
VKLRGYRIEPGEIEAALRTLPGVSECAVVLRHDAGQPALVAYAVPARGARLDGAEVRRALAGLLPEHMVPSAVVVLEKMP
LNANSKLDRAALPAPGFALLEVVPPSTPLEADICAMWRDTLGLPEVGVTQNFFEMGGNSMAALRILGRIRKLKPEADVAI
ADLFNHQTIRDLATAIERGPRPGGGQLIHLRSTGRRPILYCFPGLLVSTREYVKLVDHLGPDQPATGFICYSLAEDKGRE
ASVTEITARYAELVRAHSKGEPCFFLGWSWGGLLAYEAARMLGSDIDLKLIGMIDVCDMDTEFAIGAIPRFAPGEREALA
ARVEAWLARTPMAARWHDLIGAMDALAYDQFLRFVGNSPEGLPEDGPDIGSREHTFWVLIDNALIFRRHKMLPHDCPIQP
WAAADSLNRGLNLIDWRQLSRRAAPAEIIEGTTHLHIIGAPAFHARFARKLDEAMTGFEQAAE

Specific function: Activates the 7th to 12th amino acids (Val, D-Val, Trp, D-Leu, Xaa and D-Leu) in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 8th (D-Val), the 10th (D- Leu) an

COG id: COG1020

COG function: function code Q; Non-ribosomal peptide synthetase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 6 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=577, Percent_Identity=23.3968804159445, Blast_Score=103, Evalue=1e-21,
Organism=Homo sapiens, GI58082049, Length=523, Percent_Identity=23.7093690248566, Blast_Score=87, Evalue=1e-16,
Organism=Homo sapiens, GI157311624, Length=523, Percent_Identity=23.9005736137667, Blast_Score=84, Evalue=6e-16,
Organism=Homo sapiens, GI157311622, Length=523, Percent_Identity=23.9005736137667, Blast_Score=84, Evalue=6e-16,
Organism=Homo sapiens, GI187761345, Length=505, Percent_Identity=24.1584158415842, Blast_Score=84, Evalue=9e-16,
Organism=Homo sapiens, GI187761343, Length=505, Percent_Identity=24.1584158415842, Blast_Score=84, Evalue=9e-16,
Organism=Homo sapiens, GI42544132, Length=522, Percent_Identity=21.8390804597701, Blast_Score=80, Evalue=1e-14,
Organism=Homo sapiens, GI156151445, Length=584, Percent_Identity=21.4041095890411, Blast_Score=78, Evalue=7e-14,
Organism=Escherichia coli, GI1786801, Length=801, Percent_Identity=29.8377028714107, Blast_Score=237, Evalue=3e-63,
Organism=Escherichia coli, GI145693145, Length=508, Percent_Identity=24.4094488188976, Blast_Score=83, Evalue=1e-16,
Organism=Escherichia coli, GI1788107, Length=479, Percent_Identity=24.6346555323591, Blast_Score=74, Evalue=6e-14,
Organism=Escherichia coli, GI1790505, Length=528, Percent_Identity=25.1893939393939, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17556356, Length=678, Percent_Identity=24.9262536873156, Blast_Score=158, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI32563687, Length=461, Percent_Identity=25.8134490238612, Blast_Score=112, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17558820, Length=450, Percent_Identity=24.6666666666667, Blast_Score=97, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17550940, Length=574, Percent_Identity=22.4738675958188, Blast_Score=93, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17560140, Length=488, Percent_Identity=23.3606557377049, Blast_Score=83, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17559526, Length=362, Percent_Identity=24.3093922651934, Blast_Score=74, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17560308, Length=362, Percent_Identity=23.4806629834254, Blast_Score=69, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319591, Length=802, Percent_Identity=24.0648379052369, Blast_Score=180, Evalue=1e-45,
Organism=Saccharomyces cerevisiae, GI6319699, Length=494, Percent_Identity=21.8623481781377, Blast_Score=91, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24648676, Length=579, Percent_Identity=28.8428324697755, Blast_Score=166, Evalue=1e-40,
Organism=Drosophila melanogaster, GI18859661, Length=360, Percent_Identity=25.8333333333333, Blast_Score=85, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24653035, Length=481, Percent_Identity=22.8690228690229, Blast_Score=84, Evalue=9e-16,
Organism=Drosophila melanogaster, GI19922652, Length=496, Percent_Identity=24.3951612903226, Blast_Score=80, Evalue=8e-15,
Organism=Drosophila melanogaster, GI161076582, Length=488, Percent_Identity=22.5409836065574, Blast_Score=78, Evalue=4e-14,
Organism=Drosophila melanogaster, GI21355181, Length=510, Percent_Identity=22.3529411764706, Blast_Score=70, Evalue=7e-12,
Organism=Drosophila melanogaster, GI21356947, Length=484, Percent_Identity=22.1074380165289, Blast_Score=70, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR023213
- InterPro:   IPR001242
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 144935; Mature: 144804

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGSAPQLQPGGRAMTHADAAVETKDHELKGYDLTPSQRRVWSLEQIGNSAVAGRPLLEL
CCCCCCCCCCCCCEEECCCHHCCCCCCCCCCCCCCCCHHHEEEHHHHCCCCCCCCHHHHH
GLSGPLDVTTLRTALDRLALRHPALRLRFRVHPGGRVLQLPDDAAALPLSVCDLSAQTSG
CCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEECCCCCCCCCHHHCCCCCCCCC
DAAHAYQRIRNELAVPDIETGVPAQAVLVRLSAHEARLLIVLHPIICDTVSLDILADSFA
HHHHHHHHHHHHCCCCCCCCCCCHHHHEEEECCCCEEEEEEEECHHHHHHHHHHHHCCEE
LLYADAEAGSAGLSLAGAPLAWLERPEASPETLSQWETRLADDHADATLPLAGRRETRVD
EEEEECCCCCCCCEECCCCHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
GARSAQLQTLGTAEAEAARAAATACGTSLALFLSAAFGVLLTRYSGQTRLKYGVALDAPL
CCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCC
GGERREIGRVADVLPLLLDLSSGLSFKDALGRVAEALDAARSHYVPFETLAQTFWVNNED
CCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCC
NGRGFLPSVHMHRPLPPAVVITPGGLRITAIAQPPLPLDADFLFISRDLPDGSIELVLDH
CCCCCCCCCCCCCCCCCEEEECCCCEEEEEEECCCCCCCCCEEEEEECCCCCCEEEEEEC
PAGLFDPRLVDRALTHLARIIGAASAGPEKSLRDIQLVSPAELEALSRPYPDGARDDPRP
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCHHHHHHCCCCCCCCCCCCCH
VHALIAGHVPRAPETPAIFFGDTVWTRAALDRYANRIANMLLAAGARRESCVAVALRRSP
HHHHHHCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCH
EAIGAILGVLKAGAAFIPVEPDHPAQRNDHILADAGVAVILTTRALRAKLRPAQGTTVIE
HHHHHHHHHHHCCCEEEECCCCCCCCCCCEEEECCCEEEEEEHHHHHHHCCCCCCCEEEE
LDAVNLAEVPDSDPLVTITDRQLAYVIYTSGSTGKPKGVAVEHGPLTRHLQATARVYEMD
EECCCHHCCCCCCCEEEEECCEEEEEEEECCCCCCCCCEEEECCCCHHHHHHHHHHHCCC
ETSRELPFLPFSSDGGHERWMVPLMLGGSIVLPDKPLWTPEETFAAMRRHGVNNASFPTT
CCCCCCCEEECCCCCCCCEEEEEEEECCEEEECCCCCCCCHHHHHHHHHCCCCCCCCCHH
YVQQLAEWAEATGEAPPVRLYSFGGEGMAQATFDLFSRALKAQTLINGYGPTETIMTPMV
HHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCE
WKVRSGTSFEGTYAPIGRAVGLRRIYVLDPDLNPVPIGVTGELYIGGDGVARGYVNRPGA
EEECCCCCCCCCCCHHHHHCCEEEEEEECCCCCEEEEEEEEEEEECCCCCCCCCCCCCCC
TAERFIPDPFGGDGGRLYASGDLARWREDGTVEFVGRVDHQVKLRGYRIEPGEIEAALRT
CHHHCCCCCCCCCCCEEEECCCHHHHCCCCCEEEEECCCCEEEEEEEECCCHHHHHHHHH
LPGVSECAVVLRHDAGQPALVAYAVPARGARLDGAEVRRALAGLLPEHMVPSAVVVLEKM
CCCHHHHHHHEECCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCHHHHCCCEEEEEECC
PLNANSKLDRAALPAPGFALLEVVPPSTPLEADICAMWRDTLGLPEVGVTQNFFEMGGNS
CCCCCCCCCHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHCCCH
MAALRILGRIRKLKPEADVAIADLFNHQTIRDLATAIERGPRPGGGQLIHLRSTGRRPIL
HHHHHHHHHHHHCCCCCCCHHHHHHCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCEEE
YCFPGLLVSTREYVKLVDHLGPDQPATGFICYSLAEDKGREASVTEITARYAELVRAHSK
EECCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCC
GEPCFFLGWSWGGLLAYEAARMLGSDIDLKLIGMIDVCDMDTEFAIGAIPRFAPGEREAL
CCCEEEEECCCCHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCHHHCCCCCCCCCHHHHH
AARVEAWLARTPMAARWHDLIGAMDALAYDQFLRFVGNSPEGLPEDGPDIGSREHTFWVL
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEE
IDNALIFRRHKMLPHDCPIQPWAAADSLNRGLNLIDWRQLSRRAAPAEIIEGTTHLHIIG
ECCCHHHHHHCCCCCCCCCCCCCCHHHHHCCCCCHHHHHHHHCCCCHHHHCCCEEEEEEE
APAFHARFARKLDEAMTGFEQAAE
CCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GGSAPQLQPGGRAMTHADAAVETKDHELKGYDLTPSQRRVWSLEQIGNSAVAGRPLLEL
CCCCCCCCCCCCEEECCCHHCCCCCCCCCCCCCCCCHHHEEEHHHHCCCCCCCCHHHHH
GLSGPLDVTTLRTALDRLALRHPALRLRFRVHPGGRVLQLPDDAAALPLSVCDLSAQTSG
CCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEECCCCCCCCCHHHCCCCCCCCC
DAAHAYQRIRNELAVPDIETGVPAQAVLVRLSAHEARLLIVLHPIICDTVSLDILADSFA
HHHHHHHHHHHHCCCCCCCCCCCHHHHEEEECCCCEEEEEEEECHHHHHHHHHHHHCCEE
LLYADAEAGSAGLSLAGAPLAWLERPEASPETLSQWETRLADDHADATLPLAGRRETRVD
EEEEECCCCCCCCEECCCCHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
GARSAQLQTLGTAEAEAARAAATACGTSLALFLSAAFGVLLTRYSGQTRLKYGVALDAPL
CCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCC
GGERREIGRVADVLPLLLDLSSGLSFKDALGRVAEALDAARSHYVPFETLAQTFWVNNED
CCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCC
NGRGFLPSVHMHRPLPPAVVITPGGLRITAIAQPPLPLDADFLFISRDLPDGSIELVLDH
CCCCCCCCCCCCCCCCCEEEECCCCEEEEEEECCCCCCCCCEEEEEECCCCCCEEEEEEC
PAGLFDPRLVDRALTHLARIIGAASAGPEKSLRDIQLVSPAELEALSRPYPDGARDDPRP
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCHHHHHHCCCCCCCCCCCCCH
VHALIAGHVPRAPETPAIFFGDTVWTRAALDRYANRIANMLLAAGARRESCVAVALRRSP
HHHHHHCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCH
EAIGAILGVLKAGAAFIPVEPDHPAQRNDHILADAGVAVILTTRALRAKLRPAQGTTVIE
HHHHHHHHHHHCCCEEEECCCCCCCCCCCEEEECCCEEEEEEHHHHHHHCCCCCCCEEEE
LDAVNLAEVPDSDPLVTITDRQLAYVIYTSGSTGKPKGVAVEHGPLTRHLQATARVYEMD
EECCCHHCCCCCCCEEEEECCEEEEEEEECCCCCCCCCEEEECCCCHHHHHHHHHHHCCC
ETSRELPFLPFSSDGGHERWMVPLMLGGSIVLPDKPLWTPEETFAAMRRHGVNNASFPTT
CCCCCCCEEECCCCCCCCEEEEEEEECCEEEECCCCCCCCHHHHHHHHHCCCCCCCCCHH
YVQQLAEWAEATGEAPPVRLYSFGGEGMAQATFDLFSRALKAQTLINGYGPTETIMTPMV
HHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCE
WKVRSGTSFEGTYAPIGRAVGLRRIYVLDPDLNPVPIGVTGELYIGGDGVARGYVNRPGA
EEECCCCCCCCCCCHHHHHCCEEEEEEECCCCCEEEEEEEEEEEECCCCCCCCCCCCCCC
TAERFIPDPFGGDGGRLYASGDLARWREDGTVEFVGRVDHQVKLRGYRIEPGEIEAALRT
CHHHCCCCCCCCCCCEEEECCCHHHHCCCCCEEEEECCCCEEEEEEEECCCHHHHHHHHH
LPGVSECAVVLRHDAGQPALVAYAVPARGARLDGAEVRRALAGLLPEHMVPSAVVVLEKM
CCCHHHHHHHEECCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCHHHHCCCEEEEEECC
PLNANSKLDRAALPAPGFALLEVVPPSTPLEADICAMWRDTLGLPEVGVTQNFFEMGGNS
CCCCCCCCCHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHCCCH
MAALRILGRIRKLKPEADVAIADLFNHQTIRDLATAIERGPRPGGGQLIHLRSTGRRPIL
HHHHHHHHHHHHCCCCCCCHHHHHHCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCEEE
YCFPGLLVSTREYVKLVDHLGPDQPATGFICYSLAEDKGREASVTEITARYAELVRAHSK
EECCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCC
GEPCFFLGWSWGGLLAYEAARMLGSDIDLKLIGMIDVCDMDTEFAIGAIPRFAPGEREAL
CCCEEEEECCCCHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCHHHCCCCCCCCCHHHHH
AARVEAWLARTPMAARWHDLIGAMDALAYDQFLRFVGNSPEGLPEDGPDIGSREHTFWVL
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEE
IDNALIFRRHKMLPHDCPIQPWAAADSLNRGLNLIDWRQLSRRAAPAEIIEGTTHLHIIG
ECCCHHHHHHCCCCCCCCCCCCCCHHHHHCCCCCHHHHHHHHCCCCHHHHCCCEEEEEEE
APAFHARFARKLDEAMTGFEQAAE
CCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA