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The map label for this gene is rsmB [H]

Identifier: 158424806

GI number: 158424806

Start: 3639688

End: 3641031

Strand: Reverse

Name: rsmB [H]

Synonym: AZC_3182

Alternate gene names: 158424806

Gene position: 3641031-3639688 (Counterclockwise)

Preceding gene: 158424807

Following gene: 158424804

Centisome position: 67.81

GC content: 70.68

Gene sequence:

>1344_bases
GTGCCGCATGTTTCTCAGCCTGATGTTCGCTCCGTGACCCCTGCCGCCCGCCTGCAAGCCATCCTCGATCTGATGCAAGA
GGTCGACAGCGTCGACCGACCCGCCGATGCCGTCATCTCCGCCTGGTTCCGCGCGCGGCGCGACGTGGGCGCCGAGGACC
GGGGTCCGATTTCCGAAACCTATTATGCCCTGCTGCGCGCCCATGCGCGGCTGGGCTGGTGGCTCGCCCGGCATGGGCGG
GAGGACACGCCGCGCAACCGGCTGCTGGCCTTCCTCGTGCTCGACGGCAAGAAGACGCGCGATGAGGTCGCGCGCCTGTT
CTCGGGCGGGATGTCCGCCCCCGCGCCGCTCACAGACAATGAACGGGCGCTGCTGGTGAAACTGCAGGGCGGCCGCATGG
ATAGTCCCTCCATGCCGGAGGAGGTGCGCCTCGAATGCCCCGCCTGGGCGCTGGAGCCCTTCCGGAACCGGTTCGGCGCG
GAGTTCGAGCGGGAAATGGCGGCGCTGCTGACGCCCGCACCCCTCGACCTGCGCGTCAATCCCATCAAGGCCAAGCGCGA
GGACATGGTGCAGGCCCTGCGCGAGCTGGGCCTGCCGGCCGAGCCGTCGGTGAGCGCGCCCTTTGGAATCCGCGTGCGTG
AGCGGCCGTCGCTGTCGCGCCTCACCATGCTGAAAAGCGGCGAGGTGGAAATCCAGGACGAGGGCTCGCAGCTCGTCGCC
TTGCTGATGGATGCCCGGCCCGGTGAGCGGGTGGTGGACTTCTGCGCCGGAGCCGGGGGCAAGACGCTGGCGATTGCCGC
CCAGATGGCCAACAGGGGCCATGTGATCGCCTGCGATGTCATGGAAGGGCGCCTGAAGCGCGGCGCCGAACGCTTCCGAC
GGGCCGGCCTGCACAATATCGAGACGCGGCTGCTGGCGAGCGAGACCGACCGCTGGGTGAAGCGCCACAAGGGCACGTTC
GACCGTGTGCTGGTGGATGCGCCGTGCAGCGGCACGGGCACGTGGCGGCGCAATCCCGATGCCCGCTGGCGCACGCTGGG
GGCGGGGCTGGAGACGCTGCTGCCGCAGCAGGCCCGCATTCTGGCGAGCGCGGCGCGGCTGGTGAAGCCCGGCGGGCGGC
TCGTCTATGCCACCTGCTCCATGCTGCCGGACGAGAATGAGGGGCAGGTGGCGAGCTTCCTTGCAGCGCATCCCGACTTC
CGCGTCCTGCCGCTCACCGAGGTGGCGCCGCAGCTGCCGCCCTCGGCCCATCCCGACTATCTCTCGCTCACGCCCGCGCG
GCACGATATGGACGGCTTCTTCGCCGCCGTCCTCCAGCGCGCGCCGCTGCCGCCGGCCGCCTGA

Upstream 100 bases:

>100_bases
GGTCGCCGGGGTCGTCCACGCCACGGAGGCGGACCGCTCCTGAGGACAGGGCGGAACAGCGGCCCGCAGCGGATCGTCAA
GGGGAGCGCCATCGGCTAAG

Downstream 100 bases:

>100_bases
TCGGGCGCCGGCCTAGCGGCGGGGCAGGGTCACGCCCTTGGTGGTGAAGCGCTGCGTGCCGCTGCCGGGGCGCACGGGGC
GCTTGGTGCCGGCGGCCTTG

Product: tRNA/rRNA cytosine-C5-methylase

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MPHVSQPDVRSVTPAARLQAILDLMQEVDSVDRPADAVISAWFRARRDVGAEDRGPISETYYALLRAHARLGWWLARHGR
EDTPRNRLLAFLVLDGKKTRDEVARLFSGGMSAPAPLTDNERALLVKLQGGRMDSPSMPEEVRLECPAWALEPFRNRFGA
EFEREMAALLTPAPLDLRVNPIKAKREDMVQALRELGLPAEPSVSAPFGIRVRERPSLSRLTMLKSGEVEIQDEGSQLVA
LLMDARPGERVVDFCAGAGGKTLAIAAQMANRGHVIACDVMEGRLKRGAERFRRAGLHNIETRLLASETDRWVKRHKGTF
DRVLVDAPCSGTGTWRRNPDARWRTLGAGLETLLPQQARILASAARLVKPGGRLVYATCSMLPDENEGQVASFLAAHPDF
RVLPLTEVAPQLPPSAHPDYLSLTPARHDMDGFFAAVLQRAPLPPAA

Sequences:

>Translated_447_residues
MPHVSQPDVRSVTPAARLQAILDLMQEVDSVDRPADAVISAWFRARRDVGAEDRGPISETYYALLRAHARLGWWLARHGR
EDTPRNRLLAFLVLDGKKTRDEVARLFSGGMSAPAPLTDNERALLVKLQGGRMDSPSMPEEVRLECPAWALEPFRNRFGA
EFEREMAALLTPAPLDLRVNPIKAKREDMVQALRELGLPAEPSVSAPFGIRVRERPSLSRLTMLKSGEVEIQDEGSQLVA
LLMDARPGERVVDFCAGAGGKTLAIAAQMANRGHVIACDVMEGRLKRGAERFRRAGLHNIETRLLASETDRWVKRHKGTF
DRVLVDAPCSGTGTWRRNPDARWRTLGAGLETLLPQQARILASAARLVKPGGRLVYATCSMLPDENEGQVASFLAAHPDF
RVLPLTEVAPQLPPSAHPDYLSLTPARHDMDGFFAAVLQRAPLPPAA
>Mature_446_residues
PHVSQPDVRSVTPAARLQAILDLMQEVDSVDRPADAVISAWFRARRDVGAEDRGPISETYYALLRAHARLGWWLARHGRE
DTPRNRLLAFLVLDGKKTRDEVARLFSGGMSAPAPLTDNERALLVKLQGGRMDSPSMPEEVRLECPAWALEPFRNRFGAE
FEREMAALLTPAPLDLRVNPIKAKREDMVQALRELGLPAEPSVSAPFGIRVRERPSLSRLTMLKSGEVEIQDEGSQLVAL
LMDARPGERVVDFCAGAGGKTLAIAAQMANRGHVIACDVMEGRLKRGAERFRRAGLHNIETRLLASETDRWVKRHKGTFD
RVLVDAPCSGTGTWRRNPDARWRTLGAGLETLLPQQARILASAARLVKPGGRLVYATCSMLPDENEGQVASFLAAHPDFR
VLPLTEVAPQLPPSAHPDYLSLTPARHDMDGFFAAVLQRAPLPPAA

Specific function: Unknown

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=296, Percent_Identity=30.0675675675676, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI76150623, Length=296, Percent_Identity=30.0675675675676, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI32698918, Length=186, Percent_Identity=34.4086021505376, Blast_Score=102, Evalue=9e-22,
Organism=Homo sapiens, GI8922322, Length=305, Percent_Identity=30.1639344262295, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI270288816, Length=305, Percent_Identity=30.1639344262295, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI270288818, Length=305, Percent_Identity=30.1639344262295, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI23199998, Length=305, Percent_Identity=30.1639344262295, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI301336155, Length=274, Percent_Identity=28.4671532846715, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI39995082, Length=297, Percent_Identity=26.2626262626263, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI11545785, Length=271, Percent_Identity=28.4132841328413, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI40316918, Length=169, Percent_Identity=30.1775147928994, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI2367212, Length=407, Percent_Identity=27.027027027027, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI87081985, Length=299, Percent_Identity=29.4314381270903, Blast_Score=110, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17536757, Length=298, Percent_Identity=30.5369127516779, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI25143471, Length=289, Percent_Identity=29.4117647058824, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17509941, Length=163, Percent_Identity=31.9018404907975, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6324268, Length=285, Percent_Identity=27.719298245614, Blast_Score=103, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6319447, Length=187, Percent_Identity=31.5508021390374, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI22024126, Length=285, Percent_Identity=30.1754385964912, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24668781, Length=241, Percent_Identity=31.5352697095436, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI19920494, Length=166, Percent_Identity=34.9397590361446, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21356513, Length=259, Percent_Identity=30.8880308880309, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21355201, Length=180, Percent_Identity=33.8888888888889, Blast_Score=82, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 49269; Mature: 49138

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: PS01153 NOL1_NOP2_SUN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHVSQPDVRSVTPAARLQAILDLMQEVDSVDRPADAVISAWFRARRDVGAEDRGPISET
CCCCCCCCCHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCHHHH
YYALLRAHARLGWWLARHGREDTPRNRLLAFLVLDGKKTRDEVARLFSGGMSAPAPLTDN
HHHHHHHHHHHHHHHHHCCCCCCCHHHEEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCC
ERALLVKLQGGRMDSPSMPEEVRLECPAWALEPFRNRFGAEFEREMAALLTPAPLDLRVN
CCEEEEEECCCCCCCCCCCHHHEECCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCEEEC
PIKAKREDMVQALRELGLPAEPSVSAPFGIRVRERPSLSRLTMLKSGEVEIQDEGSQLVA
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCHHHHHEEECCCEEEECCCHHHHH
LLMDARPGERVVDFCAGAGGKTLAIAAQMANRGHVIACDVMEGRLKRGAERFRRAGLHNI
HHHCCCCCHHHHHHHCCCCCCEEEEEEHHCCCCCEEEEHHHHHHHHHHHHHHHHCCCHHH
ETRLLASETDRWVKRHKGTFDRVLVDAPCSGTGTWRRNPDARWRTLGAGLETLLPQQARI
HHHHHHHHHHHHHHHHCCCHHHEEEECCCCCCCCCCCCCCHHHHHHHCCHHHHCHHHHHH
LASAARLVKPGGRLVYATCSMLPDENEGQVASFLAAHPDFRVLPLTEVAPQLPPSAHPDY
HHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHCCCCCEEEEHHHHCCCCCCCCCCCC
LSLTPARHDMDGFFAAVLQRAPLPPAA
EEECCCCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PHVSQPDVRSVTPAARLQAILDLMQEVDSVDRPADAVISAWFRARRDVGAEDRGPISET
CCCCCCCCHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCHHHH
YYALLRAHARLGWWLARHGREDTPRNRLLAFLVLDGKKTRDEVARLFSGGMSAPAPLTDN
HHHHHHHHHHHHHHHHHCCCCCCCHHHEEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCC
ERALLVKLQGGRMDSPSMPEEVRLECPAWALEPFRNRFGAEFEREMAALLTPAPLDLRVN
CCEEEEEECCCCCCCCCCCHHHEECCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCEEEC
PIKAKREDMVQALRELGLPAEPSVSAPFGIRVRERPSLSRLTMLKSGEVEIQDEGSQLVA
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCHHHHHEEECCCEEEECCCHHHHH
LLMDARPGERVVDFCAGAGGKTLAIAAQMANRGHVIACDVMEGRLKRGAERFRRAGLHNI
HHHCCCCCHHHHHHHCCCCCCEEEEEEHHCCCCCEEEEHHHHHHHHHHHHHHHHCCCHHH
ETRLLASETDRWVKRHKGTFDRVLVDAPCSGTGTWRRNPDARWRTLGAGLETLLPQQARI
HHHHHHHHHHHHHHHHCCCHHHEEEECCCCCCCCCCCCCCHHHHHHHCCHHHHCHHHHHH
LASAARLVKPGGRLVYATCSMLPDENEGQVASFLAAHPDFRVLPLTEVAPQLPPSAHPDY
HHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHCCCCCEEEEHHHHCCCCCCCCCCCC
LSLTPARHDMDGFFAAVLQRAPLPPAA
EEECCCCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]