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The map label for this gene is uvrB [H]

Identifier: 158424751

GI number: 158424751

Start: 3584290

End: 3586920

Strand: Reverse

Name: uvrB [H]

Synonym: AZC_3127

Alternate gene names: 158424751

Gene position: 3586920-3584290 (Counterclockwise)

Preceding gene: 158424752

Following gene: 158424750

Centisome position: 66.8

GC content: 67.12

Gene sequence:

>2631_bases
ATGGCCAAAGCATCCCGTCCCGGCAAGCTCGGTGAGCGCTCGCAGCGTCATTTCGAGCCCGCGCCCGCCCAGCCGCTCGA
TCCCGCGCTCGCGCAGTCTCTGGGGCTCAACCCCGGCGACCTCTCCGTCGATTTCGAATCGAGCGGCGCCTCCGCCACGG
TGCAGGCGCTCTCGCAACTGATCGAGAACGGGCGGCCGGAGGTGAACGGCCAAACCTGGGTGCCCCATCGCCCGCCGCGC
CCGGAGAAGAGCGAAGGCGGCATCCGCTTCGTGATGAAGAGCGACTTCCAGCCTTCGGGCGACCAGCCGCAGGCCATCAA
GGAACTGACGGAGGCTGCCCGGCAGGGCGAGCGCGATCAGGTGCTGCTGGGCGTCACCGGCTCGGGCAAGACCTTCACCA
TGGCCAAGGTGATCGAGACGCTTCAGCGCCCGGCCATCGTGCTGGCGCCCAACAAGACGCTGGCGGCGCAGCTCTATGGC
GAGTTCAAGAGCTTCTTCCCGGACAATGCCGTCGAGTACTTCGTCTCCTACTACGATTATTACCAGCCGGAAGCCTACGT
TCCGCGCACGGACACCTATATCGAGAAGGAATCCTCCATCAACGAGCAGATCGACCGCATGCGCCATGCGGCGACCCGCT
CGCTGCTGGAGCGTGACGACGTCATCATCGTTGCCTCGGTGTCCTGCATCTACGGTATCGGCTCGGTGGAGACCTACGCC
TCCATGACCTTCAAGCTGGAGGTGGGCGAGCGCATCGACCAGCGCCAGCTTCTGGCCGATCTCGTGGCCCTCCAGTACAA
GCGCATCCAGTCGGATTTCGCACGCGGCACCTTCCGGGTGCGCGGCGACGTGGTGGAAATCTTCCCCGCCCACTATGAGG
ATCGCGCCTGGCGCATCTCCCTCTTCGGTGACGAGGTGGAGAGCATCGTCGAGTTCGACCCGCTCACCGGCCACAAGACC
GGCGACATGAAGAGCGTGAAGGTCTACGCCTCCTCGCACTATGTGACGCCGCGCCCGACACTCATCCAGGCTATCACCGG
CATCAAGGCCGAGCTGAAGCACCGGCTGGACGAACTCTACAAGATGGGCCGCCTGCTGGAAGCGCAGCGGCTGGAGCAGC
GCACCCGCTACGACATCGAGATGATGGAGGCGACGGGCAGCTGCGCCGGCATCGAGAACTATTCGCGCTGGCTGACTGGC
CGCAAGCCGGGCGAGCCGCCGCCGACCCTGTTCGAATACGTGCCCGACGACGCCATGGTCTTCATCGACGAGAGCCATGT
GACCGTGCCGCAGATCGGCGCCATGTATCGCGGCGACTTCCGCCGCAAGGCGACGCTGGCGGAATACGGCTTCCGCCTGC
CGTCCTGCATGGACAACCGCCCGCTGCGTTTCGAGGAATGGGATGCCATGCGGCCGCAGACGGTGCATGTCTCGGCCACC
CCCGGTCCTTGGGAGATGGACCGCACCGGCGGTGTCTTTGTTGAGCAGGTGATCCGTCCCACCGGCCTCATCGACCCGCC
GGTGGACATCCGCCCCGCGCGCACGCAGGTGGACGACCTCTTGGGCGAGGTGCGGGCGACCGCTGCGAAGGGCTATCGCA
GCCTCGTGACCGTGCTCACCAAGCGCATGGCGGAAGACCTCACGGAATATCTGCATGAGAACGGCATCCGCGTGCGCTAC
ATGCACTCGGACATCGACACCATCGAGCGCATCGAGATCATCCGCGACCTGCGCCTCGGCGCCTTCGACGTGCTGATCGG
CATCAACCTGCTGCGCGAGGGCCTCGACATTCCCGAGTGCGGGCTGGTGGCCATTCTGGATGCGGACAAGGAAGGCTTCC
TGCGCTCGGAGACCTCGCTCATCCAGACCATCGGCCGGGCGGCGCGAAACGTGGACGGCCGGGTGATCCTCTATGCGGAT
CACGAGACGGGCTCCATGAAGCGGGCCATGGCCGAGACCGCCCGCCGCCGCGAGAAGCAGATCGCCTACAACACCGAGCA
CGGCATCACGCCCGAGAGCGTGAAGAAGGCCATCGGCGACATCCTGAACTCGGTCTATGAGCGCGACCACGTGGCCGTGG
ACTCCGGGCTCGCGGAGGAGGGGGCGGCCTTCGGACACAATCTCAAGGCGATCATGGCGGACCTTGAGAAGCGCATGCGT
GCCGCTGCCGCCGACCTCGATTTCGAGGAGGCCGCGCGCCTGCGGGACGAGATCAAGCGCCTCCAGGCCACCGAGCTTGC
CGTCTCGGATGATCCCATGGCGCGGCAGGAGGCGGTGGACGACCGGACCGGCGGCTTCCGTGGTCCGCGCAAATACGGCA
AGGCCGCGAACCTTCCGGCTGCGGCCGCCAAGGGCAAGGGGCGGGCCCGGGCCCCGGCCAAGCCAGCCGACGATGCGGGC
ATCGGCGAGGAACAGTCCCGATACGCGCCCGACACCGGAAGCCGTGCCGGCCCCCCCGAAATGCCGCTCTATGCGGCGCG
CCCTGCGGCGCGTGCGGCCAAGCCTTCGCTGGACGACATGGGACCGGGGACGGATCGGGCCGAGCCCCTCGGTGCCGCCG
ATTTCCGTCCGGGGCCCCGCCCGGATCCCGGCACGAAGGGGTACCGCAAGGGTGGGCGTCGCAAGGGCTGA

Upstream 100 bases:

>100_bases
CTGACACGCATCGCGCGGCCGCCCGGACATCCTCCGGGCGGTCCCCTTTTGTTCCGCGTGCCATCTTCCCACTGCGCGCC
GTCGCCCCCATATTGGCGCC

Downstream 100 bases:

>100_bases
ACGGCGCACCTGCTCCCGGTGGCCCCCGTGGGGCCGCTGGCCACTCCGGCGCGGATTGGACGGTTGCAGTGAGCATCCGC
TTCTTGTGACCCGGTGCGCC

Product: excinuclease ABC subunit B

Products: NA

Alternate protein names: Protein uvrB; Excinuclease ABC subunit B [H]

Number of amino acids: Translated: 876; Mature: 875

Protein sequence:

>876_residues
MAKASRPGKLGERSQRHFEPAPAQPLDPALAQSLGLNPGDLSVDFESSGASATVQALSQLIENGRPEVNGQTWVPHRPPR
PEKSEGGIRFVMKSDFQPSGDQPQAIKELTEAARQGERDQVLLGVTGSGKTFTMAKVIETLQRPAIVLAPNKTLAAQLYG
EFKSFFPDNAVEYFVSYYDYYQPEAYVPRTDTYIEKESSINEQIDRMRHAATRSLLERDDVIIVASVSCIYGIGSVETYA
SMTFKLEVGERIDQRQLLADLVALQYKRIQSDFARGTFRVRGDVVEIFPAHYEDRAWRISLFGDEVESIVEFDPLTGHKT
GDMKSVKVYASSHYVTPRPTLIQAITGIKAELKHRLDELYKMGRLLEAQRLEQRTRYDIEMMEATGSCAGIENYSRWLTG
RKPGEPPPTLFEYVPDDAMVFIDESHVTVPQIGAMYRGDFRRKATLAEYGFRLPSCMDNRPLRFEEWDAMRPQTVHVSAT
PGPWEMDRTGGVFVEQVIRPTGLIDPPVDIRPARTQVDDLLGEVRATAAKGYRSLVTVLTKRMAEDLTEYLHENGIRVRY
MHSDIDTIERIEIIRDLRLGAFDVLIGINLLREGLDIPECGLVAILDADKEGFLRSETSLIQTIGRAARNVDGRVILYAD
HETGSMKRAMAETARRREKQIAYNTEHGITPESVKKAIGDILNSVYERDHVAVDSGLAEEGAAFGHNLKAIMADLEKRMR
AAAADLDFEEAARLRDEIKRLQATELAVSDDPMARQEAVDDRTGGFRGPRKYGKAANLPAAAAKGKGRARAPAKPADDAG
IGEEQSRYAPDTGSRAGPPEMPLYAARPAARAAKPSLDDMGPGTDRAEPLGAADFRPGPRPDPGTKGYRKGGRRKG

Sequences:

>Translated_876_residues
MAKASRPGKLGERSQRHFEPAPAQPLDPALAQSLGLNPGDLSVDFESSGASATVQALSQLIENGRPEVNGQTWVPHRPPR
PEKSEGGIRFVMKSDFQPSGDQPQAIKELTEAARQGERDQVLLGVTGSGKTFTMAKVIETLQRPAIVLAPNKTLAAQLYG
EFKSFFPDNAVEYFVSYYDYYQPEAYVPRTDTYIEKESSINEQIDRMRHAATRSLLERDDVIIVASVSCIYGIGSVETYA
SMTFKLEVGERIDQRQLLADLVALQYKRIQSDFARGTFRVRGDVVEIFPAHYEDRAWRISLFGDEVESIVEFDPLTGHKT
GDMKSVKVYASSHYVTPRPTLIQAITGIKAELKHRLDELYKMGRLLEAQRLEQRTRYDIEMMEATGSCAGIENYSRWLTG
RKPGEPPPTLFEYVPDDAMVFIDESHVTVPQIGAMYRGDFRRKATLAEYGFRLPSCMDNRPLRFEEWDAMRPQTVHVSAT
PGPWEMDRTGGVFVEQVIRPTGLIDPPVDIRPARTQVDDLLGEVRATAAKGYRSLVTVLTKRMAEDLTEYLHENGIRVRY
MHSDIDTIERIEIIRDLRLGAFDVLIGINLLREGLDIPECGLVAILDADKEGFLRSETSLIQTIGRAARNVDGRVILYAD
HETGSMKRAMAETARRREKQIAYNTEHGITPESVKKAIGDILNSVYERDHVAVDSGLAEEGAAFGHNLKAIMADLEKRMR
AAAADLDFEEAARLRDEIKRLQATELAVSDDPMARQEAVDDRTGGFRGPRKYGKAANLPAAAAKGKGRARAPAKPADDAG
IGEEQSRYAPDTGSRAGPPEMPLYAARPAARAAKPSLDDMGPGTDRAEPLGAADFRPGPRPDPGTKGYRKGGRRKG
>Mature_875_residues
AKASRPGKLGERSQRHFEPAPAQPLDPALAQSLGLNPGDLSVDFESSGASATVQALSQLIENGRPEVNGQTWVPHRPPRP
EKSEGGIRFVMKSDFQPSGDQPQAIKELTEAARQGERDQVLLGVTGSGKTFTMAKVIETLQRPAIVLAPNKTLAAQLYGE
FKSFFPDNAVEYFVSYYDYYQPEAYVPRTDTYIEKESSINEQIDRMRHAATRSLLERDDVIIVASVSCIYGIGSVETYAS
MTFKLEVGERIDQRQLLADLVALQYKRIQSDFARGTFRVRGDVVEIFPAHYEDRAWRISLFGDEVESIVEFDPLTGHKTG
DMKSVKVYASSHYVTPRPTLIQAITGIKAELKHRLDELYKMGRLLEAQRLEQRTRYDIEMMEATGSCAGIENYSRWLTGR
KPGEPPPTLFEYVPDDAMVFIDESHVTVPQIGAMYRGDFRRKATLAEYGFRLPSCMDNRPLRFEEWDAMRPQTVHVSATP
GPWEMDRTGGVFVEQVIRPTGLIDPPVDIRPARTQVDDLLGEVRATAAKGYRSLVTVLTKRMAEDLTEYLHENGIRVRYM
HSDIDTIERIEIIRDLRLGAFDVLIGINLLREGLDIPECGLVAILDADKEGFLRSETSLIQTIGRAARNVDGRVILYADH
ETGSMKRAMAETARRREKQIAYNTEHGITPESVKKAIGDILNSVYERDHVAVDSGLAEEGAAFGHNLKAIMADLEKRMRA
AAADLDFEEAARLRDEIKRLQATELAVSDDPMARQEAVDDRTGGFRGPRKYGKAANLPAAAAKGKGRARAPAKPADDAGI
GEEQSRYAPDTGSRAGPPEMPLYAARPAARAAKPSLDDMGPGTDRAEPLGAADFRPGPRPDPGTKGYRKGGRRKG

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. Upon binding of the uvrA(2)B(2) complex to a putative damaged site, the DNA

COG id: COG0556

COG function: function code L; Helicase subunit of the DNA excision repair complex

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Escherichia coli, GI1786996, Length=677, Percent_Identity=59.0841949778434, Blast_Score=790, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR006935
- InterPro:   IPR001943
- InterPro:   IPR004807
- InterPro:   IPR009055 [H]

Pfam domain/function: PF00271 Helicase_C; PF04851 ResIII; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 97180; Mature: 97049

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS50151 UVR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKASRPGKLGERSQRHFEPAPAQPLDPALAQSLGLNPGDLSVDFESSGASATVQALSQL
CCCCCCCCCCCCHHHHCCCCCCCCCCCHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHH
IENGRPEVNGQTWVPHRPPRPEKSEGGIRFVMKSDFQPSGDQPQAIKELTEAARQGERDQ
HHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCE
VLLGVTGSGKTFTMAKVIETLQRPAIVLAPNKTLAAQLYGEFKSFFPDNAVEYFVSYYDY
EEEEECCCCCEEHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHH
YQPEAYVPRTDTYIEKESSINEQIDRMRHAATRSLLERDDVIIVASVSCIYGIGSVETYA
CCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHCCCCHHHHH
SMTFKLEVGERIDQRQLLADLVALQYKRIQSDFARGTFRVRGDVVEIFPAHYEDRAWRIS
EEEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCEEEECCCCCCCCEEEEE
LFGDEVESIVEFDPLTGHKTGDMKSVKVYASSHYVTPRPTLIQAITGIKAELKHRLDELY
ECHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
KMGRLLEAQRLEQRTRYDIEMMEATGSCAGIENYSRWLTGRKPGEPPPTLFEYVPDDAMV
HHHHHHHHHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCHHHHCCCCCEEE
FIDESHVTVPQIGAMYRGDFRRKATLAEYGFRLPSCMDNRPLRFEEWDAMRPQTVHVSAT
EEECCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEECC
PGPWEMDRTGGVFVEQVIRPTGLIDPPVDIRPARTQVDDLLGEVRATAAKGYRSLVTVLT
CCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRMAEDLTEYLHENGIRVRYMHSDIDTIERIEIIRDLRLGAFDVLIGINLLREGLDIPEC
HHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCC
GLVAILDADKEGFLRSETSLIQTIGRAARNVDGRVILYADHETGSMKRAMAETARRREKQ
CEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHH
IAYNTEHGITPESVKKAIGDILNSVYERDHVAVDSGLAEEGAAFGHNLKAIMADLEKRMR
HEECCCCCCCHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHCCHHHHHHHHHHHHHH
AAAADLDFEEAARLRDEIKRLQATELAVSDDPMARQEAVDDRTGGFRGPRKYGKAANLPA
HHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCHHHCCCCCCCC
AAAKGKGRARAPAKPADDAGIGEEQSRYAPDTGSRAGPPEMPLYAARPAARAAKPSLDDM
HHHCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCEEECCCHHHHCCCCCCCC
GPGTDRAEPLGAADFRPGPRPDPGTKGYRKGGRRKG
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCC
>Mature Secondary Structure 
AKASRPGKLGERSQRHFEPAPAQPLDPALAQSLGLNPGDLSVDFESSGASATVQALSQL
CCCCCCCCCCCHHHHCCCCCCCCCCCHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHH
IENGRPEVNGQTWVPHRPPRPEKSEGGIRFVMKSDFQPSGDQPQAIKELTEAARQGERDQ
HHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCE
VLLGVTGSGKTFTMAKVIETLQRPAIVLAPNKTLAAQLYGEFKSFFPDNAVEYFVSYYDY
EEEEECCCCCEEHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHH
YQPEAYVPRTDTYIEKESSINEQIDRMRHAATRSLLERDDVIIVASVSCIYGIGSVETYA
CCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHCCCCHHHHH
SMTFKLEVGERIDQRQLLADLVALQYKRIQSDFARGTFRVRGDVVEIFPAHYEDRAWRIS
EEEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCEEEECCCCCCCCEEEEE
LFGDEVESIVEFDPLTGHKTGDMKSVKVYASSHYVTPRPTLIQAITGIKAELKHRLDELY
ECHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
KMGRLLEAQRLEQRTRYDIEMMEATGSCAGIENYSRWLTGRKPGEPPPTLFEYVPDDAMV
HHHHHHHHHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCHHHHCCCCCEEE
FIDESHVTVPQIGAMYRGDFRRKATLAEYGFRLPSCMDNRPLRFEEWDAMRPQTVHVSAT
EEECCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEECC
PGPWEMDRTGGVFVEQVIRPTGLIDPPVDIRPARTQVDDLLGEVRATAAKGYRSLVTVLT
CCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRMAEDLTEYLHENGIRVRYMHSDIDTIERIEIIRDLRLGAFDVLIGINLLREGLDIPEC
HHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCC
GLVAILDADKEGFLRSETSLIQTIGRAARNVDGRVILYADHETGSMKRAMAETARRREKQ
CEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHH
IAYNTEHGITPESVKKAIGDILNSVYERDHVAVDSGLAEEGAAFGHNLKAIMADLEKRMR
HEECCCCCCCHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHCCHHHHHHHHHHHHHH
AAAADLDFEEAARLRDEIKRLQATELAVSDDPMARQEAVDDRTGGFRGPRKYGKAANLPA
HHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCHHHCCCCCCCC
AAAKGKGRARAPAKPADDAGIGEEQSRYAPDTGSRAGPPEMPLYAARPAARAAKPSLDDM
HHHCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCEEECCCHHHHCCCCCCCC
GPGTDRAEPLGAADFRPGPRPDPGTKGYRKGGRRKG
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]