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The map label for this gene is ygcA [C]

Identifier: 158424731

GI number: 158424731

Start: 3558748

End: 3559968

Strand: Reverse

Name: ygcA [C]

Synonym: AZC_3107

Alternate gene names: 158424731

Gene position: 3559968-3558748 (Counterclockwise)

Preceding gene: 158424732

Following gene: 158424725

Centisome position: 66.3

GC content: 71.01

Gene sequence:

>1221_bases
GTGAGCGAGATGGAAGTGGAAGTCCTGCGCGTCGGCGCGCAGGGAGATGGGCTCGCGGCCGGCGGCCTGTTCGTGCCTTA
TGGCCTGCCGGGGGAGATCATCGCCGGCCGGCGCGACAAGGACCGGCTGGTGGAGCCCCGCGTCCTCAAGGCGAGCCCGG
AGCGGGTGGCCCCCGCCTGCACGCATTTCGGCCTCTGCGGCGGCTGCCTGCTCCAGCATTGGGAGGCAGCGGCCTATCAG
GCGTGGAAGCGCGGCCTGGTGGTGGACGCGGTCTCCCGCGAACGGGTCGAGGTGGAGGTGGCGCCGCTGGTGGATGCCCA
TGGCGAGGGCCGCCGCCGCGCCATCTTCCATGCCCGGCAACTGGGCAGGCGCACCGTGGTCGGCTTTGCCGAGCGCAAGT
CGCACGCCATGGTGCCGGTCACGGAATGCCCGGTGCTCTCCCCCGCCCTCGATCAGGCCCTTCCCGTGGCGCGGGCGGTG
GCCGAAGCATTGGCGGAGATGAAGAAGCCCCTCGACCTGCATGTGACCGCCACCGAGAGCGGGCTTGATCTGGACGTGCG
CGGCTCGGGCCCGCTCTCGCCCATGATCCTCATGGACCTCGCCGCCCTCGCGGATCGCTTCGATCTTGCCCGTCTCACCC
GCCACGGCGAGATGGTGGTGCAGCGCCGCCTGCCGTTCCTGCCCATGGGCCTTGCGCGCGTGGAACTGCCGCCCGCCTCC
TTCCTTCAGGCCACCGCCGCCGGCGAGGCGCTGCTGGCGCAGGCGGTGGGAGAAGGGGTGGAGGGCGCCAGAAGCGTCGC
CGATCTCTTCTGCGGCGTCGGCACCTTCGCGCTGCGGCTCGCCAGCCACGCCCGCGTGCGCGGCTATGAGAGCAACGAGA
CTGCCATCACCGCCCTGCTCAAGGCCATCCGTGGCACGCAGGGCCTCAAGAGCGTGGAAGGCGAGGTGCGCGACCTCTTC
CGCCGGCCGCTGATGGCGCAGGAGCTGGAGAAGTTCGAGGCCGTGGTCATCGATCCGCCCCGCCAGGGGGCGGAGGCGCA
GGCACGCGAACTCGCCCGCTCGAAGGTGGAACGGCTCGTCTATGTGTCCTGCTCGGCCCAGACCTTCGCGCGCGACGCCC
GCCTGCTGATCGACGGCGGCTTCCGCCTTGAGCGCGTGACGCCCTATGACCAGTTCCGCTATTCGCCCCATGTGGAACTC
GTGGGCCACTTCCACCGCTAG

Upstream 100 bases:

>100_bases
GCGAAGTCGAGGGCCTCGGCTGGCGCGTGCTGGGCCTCGCGCCGTCGCCCATCGAGGGCGGGGACGGCAATCGGGAATTT
CTTTTGGGTGCGGTGCGACC

Downstream 100 bases:

>100_bases
GGGCCTCAGCCGAAGCGGCCGGTGATGTAGCGCTGGGTGCGGGCGTCCGCCGGTGCCGTGAACAGATGGCGTGTCGTGCC
GAACTCCAGGATTTCGCCCA

Product: RNA methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MSEMEVEVLRVGAQGDGLAAGGLFVPYGLPGEIIAGRRDKDRLVEPRVLKASPERVAPACTHFGLCGGCLLQHWEAAAYQ
AWKRGLVVDAVSRERVEVEVAPLVDAHGEGRRRAIFHARQLGRRTVVGFAERKSHAMVPVTECPVLSPALDQALPVARAV
AEALAEMKKPLDLHVTATESGLDLDVRGSGPLSPMILMDLAALADRFDLARLTRHGEMVVQRRLPFLPMGLARVELPPAS
FLQATAAGEALLAQAVGEGVEGARSVADLFCGVGTFALRLASHARVRGYESNETAITALLKAIRGTQGLKSVEGEVRDLF
RRPLMAQELEKFEAVVIDPPRQGAEAQARELARSKVERLVYVSCSAQTFARDARLLIDGGFRLERVTPYDQFRYSPHVEL
VGHFHR

Sequences:

>Translated_406_residues
MSEMEVEVLRVGAQGDGLAAGGLFVPYGLPGEIIAGRRDKDRLVEPRVLKASPERVAPACTHFGLCGGCLLQHWEAAAYQ
AWKRGLVVDAVSRERVEVEVAPLVDAHGEGRRRAIFHARQLGRRTVVGFAERKSHAMVPVTECPVLSPALDQALPVARAV
AEALAEMKKPLDLHVTATESGLDLDVRGSGPLSPMILMDLAALADRFDLARLTRHGEMVVQRRLPFLPMGLARVELPPAS
FLQATAAGEALLAQAVGEGVEGARSVADLFCGVGTFALRLASHARVRGYESNETAITALLKAIRGTQGLKSVEGEVRDLF
RRPLMAQELEKFEAVVIDPPRQGAEAQARELARSKVERLVYVSCSAQTFARDARLLIDGGFRLERVTPYDQFRYSPHVEL
VGHFHR
>Mature_405_residues
SEMEVEVLRVGAQGDGLAAGGLFVPYGLPGEIIAGRRDKDRLVEPRVLKASPERVAPACTHFGLCGGCLLQHWEAAAYQA
WKRGLVVDAVSRERVEVEVAPLVDAHGEGRRRAIFHARQLGRRTVVGFAERKSHAMVPVTECPVLSPALDQALPVARAVA
EALAEMKKPLDLHVTATESGLDLDVRGSGPLSPMILMDLAALADRFDLARLTRHGEMVVQRRLPFLPMGLARVELPPASF
LQATAAGEALLAQAVGEGVEGARSVADLFCGVGTFALRLASHARVRGYESNETAITALLKAIRGTQGLKSVEGEVRDLFR
RPLMAQELEKFEAVVIDPPRQGAEAQARELARSKVERLVYVSCSAQTFARDARLLIDGGFRLERVTPYDQFRYSPHVELV
GHFHR

Specific function: Could Be A 23s rRNA (Uracil-5-)-Methyltransferase. [C]

COG id: COG2265

COG function: function code J; SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RNA M5U methyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI269784680, Length=192, Percent_Identity=28.6458333333333, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI269784676, Length=192, Percent_Identity=28.6458333333333, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI20149688, Length=192, Percent_Identity=28.6458333333333, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI269784678, Length=192, Percent_Identity=28.6458333333333, Blast_Score=66, Evalue=7e-11,
Organism=Escherichia coli, GI1789148, Length=438, Percent_Identity=29.6803652968037, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1787083, Length=168, Percent_Identity=31.547619047619, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016027
- InterPro:   IPR007848
- InterPro:   IPR010280 [H]

Pfam domain/function: PF05175 MTS [H]

EC number: NA

Molecular weight: Translated: 44207; Mature: 44075

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEMEVEVLRVGAQGDGLAAGGLFVPYGLPGEIIAGRRDKDRLVEPRVLKASPERVAPAC
CCCCEEEEEEECCCCCCEEECCEEECCCCCCHHCCCCCCHHHCCCCHHCCCCCHHHHHHH
THFGLCGGCLLQHWEAAAYQAWKRGLVVDAVSRERVEVEVAPLVDAHGEGRRRAIFHARQ
HHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCEEEEEEEEECCCCCCCHHHHHHHHH
LGRRTVVGFAERKSHAMVPVTECPVLSPALDQALPVARAVAEALAEMKKPLDLHVTATES
HCCHHHEEHHHCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCC
GLDLDVRGSGPLSPMILMDLAALADRFDLARLTRHGEMVVQRRLPFLPMGLARVELPPAS
CCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCHH
FLQATAAGEALLAQAVGEGVEGARSVADLFCGVGTFALRLASHARVRGYESNETAITALL
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
KAIRGTQGLKSVEGEVRDLFRRPLMAQELEKFEAVVIDPPRQGAEAQARELARSKVERLV
HHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHEE
YVSCSAQTFARDARLLIDGGFRLERVTPYDQFRYSPHVELVGHFHR
EEECCHHHHHCCCEEEEECCEEEEECCCHHHHCCCCCHHHHCCCCC
>Mature Secondary Structure 
SEMEVEVLRVGAQGDGLAAGGLFVPYGLPGEIIAGRRDKDRLVEPRVLKASPERVAPAC
CCCEEEEEEECCCCCCEEECCEEECCCCCCHHCCCCCCHHHCCCCHHCCCCCHHHHHHH
THFGLCGGCLLQHWEAAAYQAWKRGLVVDAVSRERVEVEVAPLVDAHGEGRRRAIFHARQ
HHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCEEEEEEEEECCCCCCCHHHHHHHHH
LGRRTVVGFAERKSHAMVPVTECPVLSPALDQALPVARAVAEALAEMKKPLDLHVTATES
HCCHHHEEHHHCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCC
GLDLDVRGSGPLSPMILMDLAALADRFDLARLTRHGEMVVQRRLPFLPMGLARVELPPAS
CCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCHH
FLQATAAGEALLAQAVGEGVEGARSVADLFCGVGTFALRLASHARVRGYESNETAITALL
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
KAIRGTQGLKSVEGEVRDLFRRPLMAQELEKFEAVVIDPPRQGAEAQARELARSKVERLV
HHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHEE
YVSCSAQTFARDARLLIDGGFRLERVTPYDQFRYSPHVELVGHFHR
EEECCHHHHHCCCEEEEECCEEEEECCCHHHHCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]